Formal Schooling Influences Two- but Not Three-Dimensional Naming Skills

The modulatory influence of literacy on the cognitive system of the human brain has been indicated in behavioral, neuroanatomic, and functional neuroimaging studies. In this study we explored the functional consequences of formal education and the acquisition of an alphabetic written language on two- and three-dimensional visual naming. The results show that illiterate subjects perform significantly worse on immediate naming of two-dimensional representations of common everyday objects compared to literate subjects, both in terms of accuracy and reaction times. In contrast, there was no significant difference when the subjects named the corresponding real objects. The results suggest that formal education and learning to read and to write modulate the cognitive process involved in processing two- but not three-dimensional representations of common everyday objects. Both the results of the reaction time and the error pattern analyses can be interpreted as indicating that the major influence of literacy affects the visual system or the interaction between the visual and the language systems. We suggest that the visual system in a wide sense and/or the interface between the visual and the language system are differently formatted in literate and illiterate subjects. In other words, we hypothesize that the pattern of interactions in the functional-anatomical networks subserving visual naming, that is, the interactions within and between the visual and language processing networks, differ in literate and illiterate subjects.     

Semantic interference on a phonological task in illiterate subjects

Previous research suggests that learning an alphabetic written language influences aspects of the auditory-verbal language system. In this study, we examined whether literacy influences the notion of words as phonological units independent of lexical semantics in literate and illiterate subjects. Subjects had to decide which item in a word- or pseudoword pair was phonologically longest. By manipulating the relationship between referent size and phonological length in three word conditions (congruent, neutral, and incongruent) we could examine to what extent subjects focused on form rather than meaning of the stimulus material. Moreover, the pseudoword condition allowed us to examine global phonological awareness independent of lexical semantics. The results showed that literate performed significantly better than illiterate subjects in the neutral and incongruent word conditions as well as in the pseudoword condition. The illiterate group performed least well in the incongruent condition and significantly better in the pseudoword condition compared to the neutral and incongruent word conditions and suggest that performance on phonological word length comparisons is dependent on literacy. In addition, the results show that the illiterate participants are able to perceive and process phonological length, albeit less well than the literate subjects, when no semantic interference is present. In conclusion, the present results confirm and extend the finding that illiterate subjects are biased towards semantic-conceptual-pragmatic types of cognitive processing.     

Cognitive and psycholinguistic skills of adults who are functionally illiterate: Current state of research and implications for adult education

The purpose of this article is to review empirical studies that have investigated the cognitive and language skills of adults who are functionally illiterate (A‐IL), that is, individuals whose literacy skills are too low to meet the literacy demands of society, even though they have attended school and are not illiterate in the strictest sense of the term. Three questions are addressed: (1) What are the types of reading and spelling difficulties that characterize adults who are A‐IL? (2) Are their written language difficulties related to cognitive or language impairments which could explain their failure to learn? (3) What are the implications of these psychological findings for adult education? Copyright © 2010 John Wiley & Sons, Ltd.     

文盲与非文盲汉字字形和语音加工的脑机制

利用功能性磁共振成像(fMRI)技术探讨文盲和非文盲汉字字形和语音加工脑机制的差异。实验1使用汉字字形和图形比较了中国人文盲和非文盲字形加工过程脑机制的左侧差异。实验2使用汉字语音和纯音比较了文盲和非文盲语音加工过程脑机制的双侧差异。结果表明文盲与非文盲汉字字形和语音加工脑机制不同,且非文盲的脑活动强。     

Learning to read facilitates the retrieval of phonological representations in rapid automatized naming: Evidence from unschooled illiterate,ex‐illiterate,and schooled literate adults

Rapid automatized naming (RAN) of visual items is a powerful predictor of reading skills. However, the direction and locus of the association between RAN and reading is still largely unclear. Here, we investigated whether literacy acquisition directly bolsters RAN efficiency for objects, adopting a strong methodological design, by testing three groups of adults matched in age and socioeconomic variables, who differed only in literacy/schooling: unschooled illiterate and ex‐illiterate, and schooled literate adults. To investigate in a fine‐grained manner whether and how literacy facilitates lexical retrieval, we orthogonally manipulated the word‐form frequency (high vs. low) and phonological neighborhood density (dense vs. spare) of the objects' names. We observed that literacy experience enhances the automaticity with which visual stimuli (e.g., objects) can be retrieved and named: relative to readers (ex‐illiterate and literate), illiterate adults performed worse on RAN. Crucially, the group difference was exacerbated and significant only for those items that were of low frequency and from sparse neighborhoods. These results thus suggest that, regardless of schooling and age at which literacy was acquired, learning to read facilitates the access to and retrieval of phonological representations, especially of difficult lexical items.     

Children with Specific Language Impairment are not impaired in the acquisition and retention of Pavlovian delay and trace conditioning of the eyeblink response

Three converging lines of evidence have suggested that cerebellar abnormality is implicated in developmental language and literacy problems. First, some brain imaging studies have linked abnormalities in cerebellar grey matter to dyslexia and specific language impairment (SLI). Second, theoretical accounts of both dyslexia and SLI have postulated impairments of procedural learning and automatisation of skills, functions that are known to be mediated by the cerebellum. Third, motor learning has been shown to be abnormal in some studies of both disorders. We assessed the integrity of face related regions of the cerebellum using Pavlovian eyeblink conditioning in 7–11 year-old children with SLI. We found no relationship between oral language skills or literacy skills with either delay or trace conditioning in the children. We conclude that this elementary form of associative learning is intact in children with impaired language or literacy development.     

Home literacy experiences and literacy acquisition among children in Guangzhou, south China

Sénéchal's research in the West with English- and French-speaking children included positive relations of the development of literacy skills with home literacy experiences. There is a need to extend this research to other countries, especially in China where few studies have been done. This study examined relations of parental reports of formal and informal home literacy variables with Chinese children's vocabulary and written language development. Consistent with previous studies in the West, informal home literacy experiences were associated with Chinese children's vocabulary knowledge, and formal literacy experiences with reading skills. These findings fit previous research which distinguishes formal and informal literacy experiences in relation to children's performance on reading and language skills, and indicates reading to children is less effective for acquisition of print-specific skills.     

Singaporean kindergartners' phonological awareness and English writing skills

This article describes the phonological awareness and English writing skills among a sample of 297 Singaporean kindergarten children, stratified by ethnicity (Chinese, Malay, and Indian), and examines the relationship between oral language and writing skills in this multilingual population. Overall, Singaporean kindergartners, nearly all of whom were bilingual, scored higher on English writing but lower on English oral language skills than U.S. norms. Despite literacy instruction that emphasized whole-word memorization, phonological awareness statistically significantly predicted English writing scores, controlling for English vocabulary, ethnicity, sex, and an interaction between English vocabulary and sex. The current study's findings highlight the possibility of developing high literacy skills among bilingual learners with low oral language skills. In addition, the study demonstrates children's development of phonological awareness in the absence of phonological awareness or phonics instruction and supports the theory that both alphabetic (phonological) processes and logographic (whole-word) processes contribute to successful English literacy achievement.     

Brain activation on pre-reading tasks reveals at-risk status for dyslexia in 6-year-old children

In this fMRI-study, 6-year-old children considered at risk for dyslexia were compared with an age-/gender-matched control group for differences in brain activation when presented with visual stimuli differing in demands for literacy processing. Stimuli were nameable pictures, brand logos familiar to children, and written words - these were either regularly spelled using early-acquired rules ("alphabetic") or more complex ("orthographic"). Brain responses distinguished between the presentation conditions, as a function of group, within many cortical areas. Activation in the alphabetic and orthographic conditions in the left angular gyrus correlated with individual at-risk index scores, and activation in inferior occipito-temporal regions further indicated differential activation for the two groups related to orthographic processing, especially. Since similar patterns are reported in adult dyslexics when processing written words, it appears that sensitivity to the cortical differentiation of reading networks is established prior to formal literacy training.     

Brain-behavior relationships in reading acquisition are modulated by socioeconomic factors

Functional neuroimaging may provide insights into the achievement gap in reading skill commonly observed across socioeconomic status (SES). Brain activation during reading tasks is known to be associated with individual differences in children's phonological language skills. By selecting children of equivalent phonological skill, yet diverse socioeconomic backgrounds, we use functional magnetic resonance imaging (fMRI) to demonstrate that a child's experience, as operationalized by SES, can systematically modulate the relationship between phonological language skills and reading-related brain activity in left fusiform and perisylvian regions. Specifically, at lower socioeconomic levels, individual differences in skill result in large differences in brain activation. In contrast, as SES increases, this relationship between phonological language skill and activation is attenuated. Socioeconomic background factors are thus found to modulate brain-behavior relationships in reading, indicating that cognitive, social, and neurobiological influences on reading development are fundamentally intertwined.     

The neural bases of complex tool use in humans

The behaviors involved in complex human tool use cut across boundaries traditionally drawn between social, cognitive, perceptual and motor processes. Longstanding neuropsychological evidence suggests a distinction between brain systems responsible for representing: (1) semantic knowledge about familiar tools and their uses, and (2) the acquired skills necessary for performing these actions. Contemporary findings in functional neuroimaging support and refine this distinction by revealing the distributed neural systems that support these processes and the conditions under which they interact. Together, these findings indicate that behaviors associated with complex tool use arise from functionally specialized networks involving temporal, parietal and frontal areas within the left cerebral hemisphere.     

Executive control emerging from dynamic interactions between brain systems mediating language, working memory and attentional processes

In this theoretical paper, we review findings from a series of recent behavioral and functional neuroimaging studies of working memory and executive control which provide evidence for the following theses: 1. Working memory in humans is represented by two brain systems which differ from each other with respect to their functional-neuroanatomical organization and probably also with respect to their evolutionary origin. 2. One of these brain systems relies on prefronto-parietal and prefronto-temporal cortical networks that presumably also mediate attentional selection by the top-down modulation of domain-specific sensory association areas towards behaviorally relevant information. 3. The other system is implemented by mainly left-hemispheric premotor and parietal brain regions which to a greater part also underlie language functions and which may also be involved in the retrieval and maintenance of verbal goal representations during advance preparation for task switches. 4. Context-sensitive behavioral adaptation is supported by a complementary mechanism for the detection of conflicts and for the triggering of cognitive control processes that relies on parts of the medial frontal cortex. Based on these empirical results reported in the literature we propose a neurocognitive model of executive control according to which the human ability to flexibly adapt to changing behavioral requirements, i.e. executive control, depends on dynamic and context-sensitive interactions between these brain systems.     

Combined functional and causal connectivity analyses of language networks in children: a feasibility study

Instead of assessing activation in distinct brain regions, approaches to investigating the networks underlying distinct brain functions have come into the focus of neuroscience research. Here, we provide a completely data-driven framework for assessing functional and causal connectivity in functional magnetic resonance imaging (fMRI) data, employing Granger's causality. We investigate the networks underlying story processing in 17 healthy children (8f, 9m, 10.4+/-2.8 years, 6.5-15.4 years). Extensive functional connectivity exists between brain regions, including some not detected in standard random effects analyses. Causal connectivity analyses demonstrate a clear dominance of left-sided language regions for both forward and backward interactions with other network nodes. We believe our approach to be useful in helping to assess language networks in the normal or pathological setting; it may also aid in providing better starting estimates for the more hypothesis-driven approaches like structural equation or dynamic causal modeling.     

Alphabet knowledge and early literacy skills in French beginning readers

Numerous studies in various alphabetic languages have shown that letter knowledge is a strong predictor of reading and spelling achievement. However, this issue has rarely been addressed in French. Three studies are reported in order to examine the question of the development of letter knowledge in connection with literacy skills in French beginning readers before and during formal instruction. The level of the different alphabet-related skills was studied in kindergarten and two short longitudinal studies were conducted while the children were receiving formal instruction. In Study 1, upper-case letters resulted in higher scores. In Study 2, in the case of consonants, no significant advantage of phoneme position in letter names was found. In Study 3 children with good letter-name knowledge in kindergarten performed better in reading and spelling tasks in first grade. Finally, alphabet knowledge is viewed as a multi-faceted type of knowledge, which includes different skills such as alphabet reciting, letter naming and letter-sound knowledge. An early ability in this domain could be highly predictive of subsequent literacy development.     

Syntactic processing in the human brain: what we know, what we don't know, and a suggestion for how to proceed

For every claim in the neuroimaging literature about a particular brain region supporting syntactic processing, there exist other claims implicating the target region in different linguistic processes, and, in many cases, in non-linguistic cognitive processes (e.g., Blumstein, 2009). We argue that traditional group analysis methods in neuroimaging may obscure functional specificity because of inter-subject anatomical variability (Fedorenko & Kanwisher, 2009). In Fedorenko, Hsieh, Nieto-Castanon, Whitfield-Gabrieli, and Kanwisher (2010) we presented a functional localizer that allows quick and reliable identification of key language-sensitive regions in each individual brain. This approach enables pooling data from corresponding functional regions across subjects rather than from the same locations in stereotaxic space that may differ functionally due to inter-subject anatomical variability. In the current paper we demonstrate that the individual-subjects functional localization approach is superior to the traditional methods in its ability to distinguish among conditions in a brain region’s response. This ability is at the core of all neuroimaging research and is critical for answering questions of functional specialization (e.g., does a brain region specialize for processing syntactic aspects of the linguistic signal), which is in turn essential for making inferences about the precise computations conducted in each brain region. Based on our results, we argue that supplementing existing methods with an individual-subjects functional localization approach may lead to a clearer picture of the neural basis of syntactic processing, as it has in some other domains, such as high-level vision (e.g., Kanwisher, 2010) and social cognition (e.g., Saxe & Kanwisher, 2003).     

Class size effects on literacy skills and literacy interest in first grade: A large-scale investigation

This article examines the impact of class size on literacy skills and on literacy interest in beginning readers from zones with specific educational needs in France. The data came from an experiment involving first graders in which teachers and pupils were randomly assigned to the different class types (small classes of 10-12 pupils vs. regular classes of 20-25 pupils).Globally, the findings reveal that class size has a (small) impact on the two basic literacy skills, reading (word recognition task) and spelling (word production task). Children with high literacy interest made more progress than children with low literacy interest. The analysis also explores the effect of four factors - early schooling, age, first language and socio-economic status - on the same type of literacy skills as above. Smaller classes most specifically improved performances in two types of population: children whose first language is French and children from intermediate and average socio-economic brackets. This means, in contrast, that neither the children from the most disadvantaged backgrounds nor the children whose first language was not French benefited from the use of smaller first grade classes. Data in this experiment are examined in the light of studies on the connections between class size, classroom procedures and pupils' engagement.     

语言功能偏侧化及其与利手、功能连接的关系

对大脑语言功能偏侧化的探索起始于早期对脑损伤病人的研究。现代脑影像学研究发现, 语言功能偏侧化涉及额叶、颞叶、扣带回、梭状回和辅助运动区等脑区。语言偏侧化与利手和静息态功能连接之间的关系表现为：右利手的语言优势位于左半球, 而左利手的则分布在左半球、右半球或两个半球; 语言功能偏侧化与利手系数、静息态半球内功能连接之间具有正相关关系, 与半球间功能连接呈负相关, 并且语言功能偏侧化与静息态功能连接之间的关系在左右利手个体之间存在差异。总之, 大脑语言功能偏侧化、利手和静息态功能连接三者之间存在相互影响, 基于脑连接和遗传机制的研究将有望揭示出其底层的神经生理机制。     

发展性阅读障碍书写加工缺陷及其神经机制

发展性阅读障碍是学习障碍的主要类型之一, 严重影响个体认知、情感与社会适应性的发展。书写与阅读关系密切, 阅读障碍者常常表现出书写加工缺陷。在行为层面, 阅读障碍者书写缺陷表现在书写质量差、速度慢和停顿多等多个方面。在脑机制层面, 脑成像研究发现, 阅读障碍者书写加工缺陷与字形加工脑区活动, 以及字形与运动区脑功能与结构连接异常有关。总体而言, 阅读障碍者书写过程中的字形通达缺陷的证据比较充分, 但字形与运动编码的衔接以及运动执行是否存在困难, 尚缺乏研究证据。相对于字母语言, 书写与阅读的关系在汉语中更为紧密, 汉语阅读障碍的书写研究将为开发汉语特色的诊治方案提供重要指导。