Brouwer’s Notion of ‘Egoicity’

Axiomathes - According to Brouwer’s ‘theory of the exodus of consciousness’, our experience includes ‘egoicity’, a distinct kind of feeling. In this paper, we (i)...     

Ätiologie und Pathogenese der Migräne

Migräne ist eine weltweit sehr häufige Erkrankung, die zu einer erheblichen Beeinträchtigung der Lebensqualität Betroffener führen kann. Bereits zu Beginn der Migräneattacke konnte eine Aktivierung des Hypothalamus gezeigt werden. Ein wesentlicher Aspekt ist dann die nachfolgende Aktivierung des trigeminovaskulären Systems. Hier spielt das Neuropeptid Calcitonin Gene-Related Peptide (CGRP) eine tragende Rolle. Durch die Aktivierung nozizeptiver Fasern kommt es zur Reizweiterleitung nach zentral in den Hirnstamm und über periphere und zentrale Sensibilisierung zu den typischen migräneartigen Kopfschmerzen. Durch besseres Verständnis der Pathophysiologie der Migräne ist es zuletzt gelungen, eine medikamentöse Prophylaxe zu entwickeln, die spezifisch in die komplexe Abfolge der Migränekaskade eingreift, indem das CGRP bzw. sein Rezeptor durch spezifische monoklonale Antikörper blockiert werden.     

The Multidimensional Structure of ‘better than’

Axiomathes - According to the mixed lexicographic/additive account of ‘better than’ and similar aggregative value comparatives like ‘healthier than’, values are...     

It Just Doesn’t Feel Right: OCD and the ‘Scaling Up’ Problem

The ‘scaling up’ objection says non-representational ecological-enactive accounts will be unable to explain ‘representation hungry’     

Hermann levin goldschmidt. Contradiction set free. Translated by John Koster. London,UK: Bloomsbury Academic, 2020. 152 pp. + ix. ISBN: 978-1-350-077,979-3

Continental Philosophy Review - This review explores the complex and nuanced views of Hermann Levin Goldschmidt’s conception of “setting contradiction free” in order to allow for...     

Unser Leben mit Alzheimer – wie Angehörige Demenz erleben

psychopraxis. neuropraxis - Viele Demenzpatienten werden in der eigenen Familie, oft vom Partner betreut. Besonders die Verhaltensauffälligkeiten dementer Patienten belasten diese...     

Flow and structure of time experience – concept,empirical validation and implications for psychopathology

We present a conceptual framework on the experience of time and provide a coherent basis on which to base further inquiries into qualitative approaches concerning time experience. We propose two Time-Layers (Macro-Layer and Micro-Layer) and two Time-Formats (Flow and Structure) forming four Time-Domains. Micro-Flow and Micro-Structure represent the implicit phenomenal basis, from which the explicit experiences of Macro-Flow and Macro-Structure emerge. Complementary to this theoretical proposal, we present empirical results from qualitative content analysis obtained from 25 healthy participants. The data essentially corroborate the theoretical proposal. With respect to Flow, the phenomenally accessible time experience appeared as a continuous passage reaching from the past through the present into the future. With respect to Structure, the individual present was embedded in the individual biography, emerging from past experiences and comprising individual plans and goals. New or changing plans and goals were being integrated into the existing present, thus forming a new present. The future appeared as changeable within the present, by means from the past, and therefore as a space of potential opportunities. Exemplarily, we discuss these results in relation to previous empirical findings on deviant experiences of time in Autism Spectrum Disorder (ASD) that is presumably characterized by a breakdown of Flow and concomitant compensatory repetition resulting in an overly structured time. Finally, we speculate about possible implications of these findings both for psychopathological and neuroscientific research.