精浆果糖及抗精子抗体对不孕不育影响的探究

探讨精浆果糖及精浆抗精子抗体与精子参数关系对男性不育患者的影响情况,为临床诊断、治疗提供依据.使用SQA-V全自动精子质量分析仪对50例男性不育患者精液标本进行常规分析,精浆果糖采用间苯二酚比色法进行测定,抗精子抗体采用间接免疫荧光法进行测定.男性不育症患者中,精浆果糖浓度异常组精子浓度显著高于精浆果糖浓度正常组,两组比较差异有统计学意义(P<0.01);而精子总活力和前向运动精子率与精浆果糖浓度正常组相比,差异无统计学意义(P>0.05);精浆果糖浓度与精子活动力指数(SMI)呈现出负相关的关系(r=-0.372).抗精子抗体阴性组精子浓度、精子总活力、前向运动精子率及SIM均高于阳性组,两组比较差异有统计学意义(P<0.05).精浆果糖浓度与精子浓度关系密切,与SMI呈现出显著负相关的关系;抗精子抗体对精液浓度、精子总活力、前向运动精子率及SMI均有明显影响;检测精浆果糖及抗精子抗体对男性不孕不育患者有重要的参考价值.     

中国文化下伴侣身高偏好的性别二态性研究

本研究首次考察中国文化下伴侣身高性别二态性偏好,验证Pawlowski潜在伴侣身高偏好条件性假设,并探讨性别角色对身高偏好的影响。结果表明：（1）选择不同身高搭配组的男女身高均有显著差异,低个男性和高个女性会选择和自已身高接近的伴侣高度。（2）男性对伴侣身高要求比女性更宽容。（3）不同性别角色类型被试对身高偏好无显著差异。     

体外冲击波与传统方法治疗腰椎间盘突出症疗效比较

比较放散式体外冲击波与传统保守治疗腰椎间盘突出症的临床疗效及生命质量评价。对2010年6月至fi013年6月收治且获得随访的257例腰椎间盘突出症患者进行分析,其中男139例,女118例。根据治疗方式不同随机分为两组,并在治疗前后应用日本骨科学会（JOA）下腰痛评分法及视觉模拟评分（VAS）进行疗效评价,应用健康调查评分量表SF-36进行生活质量评价。对患者进行随访1周～12周,平均（10．0±3．4）周,治疗组治疗后2周和4周VAS评分低于对照组,治疗后1周、2周及4周JOA评分高于对照组,治疗后4周、8周和12周的生理机能、生理职能、总体健康、情感职能和躯体疼痛得分高于对照组,差异有统计学意义（P〈0．05）。放散式体外冲击波治疗腰椎间盘突出症疗效较好,并能够较好地提高患者的生活质量。     

代际团结潜在类别与关系质量对自陈健康及幸福感的影响

本研究考察了成年子女与其父母的代际关系中团结和关系质量对代际双方身体和心理结果的影响。研究1中,对中国成年子女（N=1283）的潜在类别分析结果显示是六种代际团结类别,多项逻辑回归表明两代人的特征会影响团结潜在类别和关系质量。研究2中,对367对中国成年子女-父母（N=734）的报告进行等级线性建模,行动者-搭档互依模型结果指出好的团结潜在类别（自我和搭档报告的）和好的关系质量（自我报告的）与两代人的高幸福感相关,好的团结潜在类别（自我和搭档报告的）和好的关系质量（自我和搭档报告的）预测了两代人的低心理苦恼;其中代际和性别调节了团结类别和关系质量对自我报告健康及幸福感的作用,同时,两代人团结类别的交互作用和评价的相似性也影响了幸福感和心理苦恼。     

肥胖男性血浆脂联素水平及影响因素

检测正常男性血浆脂联素水平,探讨其与各检测指标之间的相关性。选取正常男性96例,按体重指数（BMI）将上述两组分为2个亚组：肥胖（BMI≥25kg／m^2）组40例及体重正常（BMI〈25kg／m^2）组56例,测定空腹血浆脂联素浓度。肥胖组的血浆脂联素水平[（7．48±3．4）μg／m1]明显低于体重正常组[（10．57±4．73）μg／m1],差异有显著的统计学意义（P〈0．01）。相关分析显示血浆脂联素与体重指数（BMI）、腰围（WC）、血压（BP）、总胆固醇（TC）、血清胰岛素（FINs）、胰岛素抵抗指数（HOMA-IR）之间存在负相关,与高密度脂蛋白胆固醇（HDL-C）正相关。BMI、WC、HOMA-IR为影响血浆脂联素水平的独立因素。男性肥胖者血浆脂联素水平较体重正常者明显降低,血浆脂联素水平可能与肥胖及其相关疾病相关。     

精原干细胞移植治疗男性不育症的伦理学问题

精原干细胞是精子发生的起始,精原干细胞既能分化产生成熟精子又具有自我更新能力以维持自身数量的恒定。精原干细胞移植技术应用于治疗男性不育症,只需将一定数量的供体干细胞植入到受体睾丸的精曲小管内,就能重新建立生精功能。显然,精原干细胞移植在治疗男性不育症有广阔的前景,同时使传统的道德伦理面临着前所未有的困惑。     

精原干细胞移植治疗男性不育症的伦理学问题

精原干细胞是精子发生的起始,精原干细胞既能分化产生成熟精子又具有自我更新能力以维持自身数量的恒定.精原干细胞移植技术应用于治疗男性不育症,只需将一定数量的供体干细胞植入到受体睾丸的精曲小管内,就能重新建立生精功能.显然,精原干细胞移植在治疗男性不育症有广阔的前景,同时使传统的道德伦理面临着前所未有的困惑.     

情绪对危机决策质量的影响

为探究情绪在危机情境下对决策质量的影响,研究通过影片诱发实验情绪,运用实验室实验考察了以情绪变量为主导、包括性别和任务难度等在内的相关因素对危机决策的作用机制。结果发现：（1）随着危机决策任务难度的增加,个体用于决策的时间显著增长,且性别与情绪类型间存在显著的二次交互作用;（2）在危机情境下,男性的产生新方案率明显高于女性;（3）男性被试对危机决策过程的自信程度显著高于女性,且情绪与难度变量之间交互作用显著;（4）个体对于自身危机决策结果的满意程度,在性别、情绪和难度变量之间存在显著的三次交互效应。     

双元孝道代际传递:亲子性别和子女年龄的调节作用

配对调查了591户家庭的亲子被试,考察了亲子女性别、子女年龄对双元孝道代际传递的影响。结果显示：（1）权威性孝道和互惠性孝道分别在父亲、母子与子女之间具有相似传递模式,但母亲互惠性孝道还能够预测子女权威性孝道;（2）子女性别能显著调节整个模型,母亲互惠性孝道能预测男性子女权威性孝道,但不能预测女性子女的权威性孝道,且母子之间互惠性孝道传递效应显著高于母女,并显著高于父子之间的同一路径系数;（3）子女年龄对模型的部分路径系数具有显著调节作用,母亲互惠性孝道仅能预测成年子女权威性孝道,母亲对成年子女的互惠性孝道代际传递效应显著高于父亲对成年子女,而父亲对青少年子女的互惠性孝道代际传递效应显著高于其对成年子女。据此研究结果,亲子性别和子女年龄是影响双元孝道代际传递的重要“传递带”。     

榄香烯联合替莫唑胺与单药替莫唑胺在 NSCLC 脑转移放疗后维持治疗中的比较研究

探讨榄香烯注射液联合替莫唑胺在非小细胞肺癌（NSCLC）脑转移患者放疗后维持治疗的疗效,将46例NSCLC脑转移放疗后患者,随机分为联合治疗组和对照组,分别采用榄香烯联合替莫唑胺和单药替莫唑胺维持化疗,观察两组疗效、免疫指标、不良反应及生存分析。结果显示两组无进展生存期（PFS）、总生存期（OS）差异无统计学意义（P＞0．05）。总缓解率及卡氏功能状态评分（KPS）两组比较差异有统计学意义（P＜0．05）。联合治疗组免疫功能提高,化疗不良反应减轻。榄香烯联合替莫唑胺维持治疗可以提高NSCLC脑转移患者放疗后的总缓解率,改善生活质量,减轻化疗的不良反应,应用安全。     

The role of semantic memory in short-term recall: effect of strategic retrieval ability in an elderly population

The present paper examines the relationship between two classic phenomena: semantic effects in short-term recall (STR) tasks, which are interpreted as indicating the involvement of long-term memory (LTM) in the functioning of short-term memory, on the one hand, and the existence of individual differences amongst elderly people in strategic retrieval ability (i.e., the ability to activate representations in LTM in a controlled way) on the other hand. Forty elderly participants completed a STR task under four different conditions which were thought to differentially involve LTM representations. Several executive functions, among which the strategic retrieval ability, were evaluated. The results showed that the participants who obtained the best performances in terms of strategic retrieval ability, and only in this executive ability, also exhibited better performances in the STR task, in particular when this task was performed under conditions which favored the use of LTM.     

双语Stroop效应的性别差异研究

虽然许多研究发现男性和女性在语言能力上存在显著差异,但性别差异是否影响第二语言的水平和学习能力尚存在争议,相关研究较少。Stroop范式是语言研究的经典方法,它利用颜色信息和语义信息的相互干扰推论被试心理词典的表征结构。本研究利用此范式探讨不同性别的第二语言学习者在言语表征上的差异。结果显示被试性别与文字材料、性别与刺激类型均存在显著的交互作用,表明不同性别被试在第二语言表征上存在显著差异。     

夫妻依恋风格、婚姻归因与婚姻质量的关系

本研究采用主—客体互倚模型(actor-partner interdependence model,APIM)的方法深入探讨夫妻的依恋风格、婚姻归因与自身及配偶感知到的婚姻质量之间的关系。以方便取样的方式在北京地区选取155对夫妻,采用Brennan等(1998)编制的亲密关系经历量表(ECR),Stander编制的婚姻归因量表(MAQ)和Spanier编制的婚姻质量问卷(DAS),要求夫妻双方分别报告其依恋风格、婚姻归因方式和感知到的婚姻质量。通过配对t检验、相关分析和结构方程模型分析发现:(1)夫妻对婚姻质量的总体知觉较为一致,但丈夫的婚姻满意度显著高于妻子;(2)夫妻双方在回避依恋和焦虑依恋两个分量表上不存在显著差异,但在婚姻归因上,妻子比丈夫表现出了更多的消极归因;(3)妻子的消极依恋显著地负向预测自身感知到的婚姻质量,而丈夫的消极依恋对自身感知到的婚姻质量没有显著影响;(4)在控制了丈夫、妻子的依恋风格、归因方式对其自身婚姻质量的主体效应之后,丈夫的依恋风格不能显著预测妻子感受到的婚姻质量,但其归因方式可以显著地预测妻子感受到的婚姻质量;然而妻子的归因方式并不能显著预测丈夫的婚姻质量。     

Differential testosterone secretory capacity of the testes of aggressive and nonaggressive house mice during ontogeny

In this study, testosterone secretory capacity of testicular Leydig cells during ontogeny was determined in males of an aggressive and a nonaggressive genetic selection line of wild house mice. Neonates, 23-day-old prepubertals, and adult male mice were studied. A morphometric method was used to quantify 3β-hydroxy steroid dehydrogenase (3β-3HSD)-stained Leydig cells in testicular sections to determine testosterone secretory capacity. We consider this parameter to reflect circulating testosterone in the plasma. The results of this study show that the testosterone secretory capacity of Leydig cells in the testis changes differentially during development in males of the aggressive and nonaggressive selection lines. This capacity is highest in the aggressive selection line males at adulthood and at the prepubertal age of 23 days. Surprisingly, at birth, the highest T-secretory capacity was observed in the males of the nonaggressive selection line. The significance of an interaction between genetic factors and differences in perinatal testosterone for the individual variation in adult aggressive behavior is discussed.     

Long‐term memory effects on verbal short‐term memory: A replication study

The influence of lexico‐semantic language representations stored in long‐term memory (LTM) on short‐term memory (STM) performance has been studied extensively in adults. However, there are relatively few data on lexico‐semantic LTM effects on STM in children. On the other hand, the influence of phonological LTM effects on STM has been studied more extensively in children than in adults. In this study, we explored whether these different LTM effects on verbal STM could be replicated in both adults and children by administering immediate serial recall tasks (ISR) for high‐ and lowfrequency words, for high‐ and low‐imageability words, for words and non‐words, and for high and low phonotactic frequency non‐words to 6‐, 8‐, and 10‐year‐old children, to adolescents and to adults. Significant word frequency, lexicality and phonotactic frequency effects were observed in all age groups, as well as a word imageability effect which was, however, weaker than the other three effects. Our data suggest that LTM effects on STM are equivalent in both children and adults.     

重症免疫性血小板减少性紫癜紧急救治方案的探讨

为了探讨重症免疫性血小板减少性紫癜(ITP)的治疗方案,回顾性分析118例接受激素(92例)或丙种球蛋白(16例)或rhTPO(10例)治疗患者的临床资料,分析疗效及不良反应。结果显示:(1)激素组、丙种球蛋白组和rhTPO组总有效率分别为76.1%、81.3%和70%,组间差异无统计学意义。复发组有效率(67.3%)明显低于初治组(83.3%,P0.05),PAIgG伴PAIgM升高组有效率明显低于不伴PAIgM升高组(P0.05);(2)血小板达峰时间:激素组为(5.70±3.68)d,丙种球蛋白组为(4.31±0.75)d,rhTPO组为(5.00±1.63)d,激素组与丙种球蛋白组间差异有统计学意义(P0.05);(3)不良反应:激素组均出现类库欣综合征表现,丙种球蛋白组未见不良反应,1例(10%)rhTPO组患者出现轻度转氨酶增高。总之,丙种球蛋白和rhTPO治疗成人重症ITP疗效好,不良反应轻微。     

Interference with prior knowledge while writing from sources: Effects of working memory capacity

Writing from sources requires the processing of both external (documentary) and internal (long-term memory; LTM) sources of information, which can sometimes interfere with each other. We hypothesised that writers with high working memory (WM) capacity would resolve interference faster than those with low-capacity WM. However, results showed that writing pause duration was shorter for low-capacity writers. This result suggests that when WM resources are limited, access to domain knowledge in LTM is restricted, thereby avoiding interference between the two sources. Results are discussed within the broader context of text composition from sources and individual differences.