Automatic and effortful information processing in unipolar major depression

The present study investigated attentional dysfunction in patients with recurrent unipolar major depression in a visual search paradigm. The attentional aspects of automatic and effortful information processing were examined. The general hypothesis was that patients with unipolar major depression would have more problems with tasks that require effortful information processing than with tasks that require only automatic information processing. A task requiring effortful processing attracts attention, is more demanding, and is instruction-driven. A task that is automatically processed does not invoke attention, is less demanding, and is stimulus-driven. The results showed that the patient group needed significantly longer reaction times on the tasks requiring more effortful information processing than the control group, but there were no significant differences between groups on tasks requiring automatic information processing. Thus it seems as if the depressed patients show an impaired profile as a function of the degree of effort a task requires.     

Enduring cognitive dysfunction in unipolar major depression: A test–retest study using the Stroop paradigm

Hammar, Å., Sørensen, L., Årdal, G., Oedegaard, K.J., Kroken, R., Roness, A. & Lund, A. (2009). Enduring cognitive dysfunction in unipolar major depression: A test–retest study using the Stroop‐paradigm. Scandinavian Journal of Psychology. The aim of the study was to investigate automatic and effortful information processing with the Stroop paradigm in a long term perspective in patients with major depressive disorder (MDD). Patients were tested at two test occasions: at inclusion with a Hamilton Depression Rating Scale (HDRS) score >18, and after 6 months, when most patients had experienced symptom reduction. The Stroop paradigm is considered to measure aspects of attention and executive functioning and consists of three conditions/cards: naming the color of the patches (Color), reading of the color‐words (Word) and naming the ink color of color‐words (Color‐Word). The Color‐Word condition is proved to be the most cognitive demanding task and requires the proband to actively suppress interference and is therefore considered to require more effortful information processing, whereas naming the color of the patches and reading the color‐words are expected to be more automatic and less cognitive demanding. A homogenous group of 19 patients with unipolar recurrent MDD according to DSM‐IV and a HDRS score of >18 were included in the study. A control group was individually matched for age, gender and level of education. Depressed patients performed equal to the control group on the Color and Word cards at both test occasions. However, the patients were impaired compared with the control group on the Color‐Word card task at both test occasions. Thus, the depressed patients showed no improvement of effortful attention/executive performance as a function of symptom reduction. The results indicate that the depressed patients showed impaired cognitive performance on cognitive demanding tasks when symptomatic and that this impairment prevailed after 6 months, despite significant improvement in their depressive symptoms.     

Outwitting the rational mind: How effortful thinking influences price cognition

Prior research presents mixed findings on how people's degrees of effortful thinking influence their reliance on heuristics and biases. Although the tenets of dual process theory would argue that effortful thinking should attenuate people's reliance on heuristics, a number of contemporary findings suggest otherwise: Effortful thinking may, in fact, enhance biased processing of information in certain instances. This research shows how, in the context of pricing, people's degrees of effortful thinking can amplify their inclination towards biased processing of price information. In five studies (n = 1,339), we find that effortful thinking induces a greater preference for nine‐ending (vs. zero‐ending) prices, and the effect is mainly driven by people's greater propensity for argument‐based decision making. Such predilection to nine‐endings attenuates with lower cognitive effort in processing price information. Moreover, when locus of deliberation shifts from price to quality, consumers' preference for nine‐ending priced options is subdued.     

Automatic and effortful processing in Attention Deficit/Hyperactivity Disorder

Twenty-five boys with Attention Deficit/Hyperactivity Disorder and 23 age-matched controls were compared on verbal memory tasks differentiating automatic versus effortful information processing. Automatic processing tasks included the recognition of new or old words in a list and the recognition of frequency of occurrence of words in a list. Effortful tasks included free recall of lists of both related and unrelated words. Hyperactive boys did not differ from controls in automatic processing capabilities but demonstrated significantly poorer effortful processing. Intercorrelations of the variables revealed high correlations between scores on effortful measures and also raise questions about the purity of automaticity in some tasks employed. Stepwise discriminant analysis demonstrated that free recall of related words (an effortful task) best discriminated between groups. Effort-related processing in hyperactive and normal children is discussed in relation to variables of motivation, affect, arousal, and other higher-order cognitive processes.     

Event-based prospective memory in depression: The impact of cue focality

This study is the first to compare event-based prospective memory performance in individuals with depression and healthy controls. The degree to which self-initiated processing is required to perform the prospective memory task was varied. Twenty-eight individuals with depression and 32 healthy controls worked on a computerised prospective memory task. Prospective cues were either presented focally or non-focally to the ongoing activity. Collapsing data across both conditions, controls outperformed individuals with depression in the prospective memory task. Overall, participants showed a poorer prospective memory performance in the non-focal condition that required self-initiated processing to a higher degree than the focal condition. Importantly, as revealed by a group by task condition interaction, groups did not differ in the focal condition, whereas, controls outperformed individuals with depression in the non-focal condition. The results are in line with the multiprocess framework of event-based prospective remembering and the cognitive-initiative account of depression-related cognitive deficits.     

The MMPI‐2 in chronic psychiatric illness

While previous studies on the MMPI‐2 in patients with schizophrenia and depression have used mixed samples of both early stage and chronic psychiatric patients. Here, it is investigated whether chronicity itself might have a differential effect on the MMPI‐2 profiles of these patients and whether demoralization ‘associated with long‐term illness’ affects the scales of the MMPI‐2. Thirty long‐term patients with schizophrenia, 30 long‐term patients with depression, and 30 healthy participants completed the MMPI‐2. Groups were compared on Clinical Scales and on the Restructured Clinical (RC) Scales. Patients with schizophrenia differed from patients with depression on 14 MMPI‐2 scales and from healthy controls on 10 scales, generally showing mean UT‐scores < 65, indicating a subjective experience of (near) normal functioning. Patients with depression differed from healthy controls on 17 scales mostly with UT‐scores > 65, indicating impaired functioning. Demoralization was higher in patients with depression than in patients with schizophrenia and both psychiatric groups differed from the healthy control group. It is concluded that long‐term patients with depression show impaired functioning and high demoralization, while long‐term patients with schizophrenia surprisingly show near normal functioning and less demoralization.     

Enhanced visual performance in obsessive compulsive personality disorder

Visual performance is considered as commanding modality in human perception. We tested whether Obsessive–compulsive personality disorder (OCPD) people do differently in visual performance tasks than people without OCPD. One hundred ten students of Ferdowsi University of Mashhad and non‐student participants were tested by Structured Clinical Interview for DSM‐IV Axis II Personality Disorders (SCID‐II), among whom 18 (mean age = 29.55; SD = 5.26; 84% female) met the criteria for OCPD classification; controls were 20 persons (mean age = 27.85; SD = 5.26; female = 84%), who did not met the OCPD criteria. Both groups were tested on a modified Flicker task for two dimensions of visual performance (i.e., visual acuity: detecting the location of change, complexity, and size; and visual contrast sensitivity). The OCPD group had responded more accurately on pairs related to size, complexity, and contrast, but spent more time to detect a change on pairs related to complexity and contrast. The OCPD individuals seem to have more accurate visual performance than non‐OCPD controls. The findings support the relationship between personality characteristics and visual performance within the framework of top‐down processing model.     

Holistic processing for faces and cars in preschool‐aged children and adults: evidence from the composite effect

The current study compared the development of holistic processing for faces and non‐face visual objects by testing for the composite effect for faces and frontal images of cars in 3‐ to 5‐year‐old children and adults in a series of four experiments using a two‐alternative forced‐choice recognition task. Results showed that a composite effect for faces was present as early as years, and none of the age groups tested showed signs of a composite effect for cars. These findings provide the first demonstration that holistic processing is already selective for faces in early childhood, and confirm existing evidence that sensitivity to holistic information in faces does not increase from 4 years to adulthood.     

False memories in Lewy‐body disease

Recently, de Boysson, Belleville, Phillips et al. (2011) found that patients with Lewy‐body disease (LBD) showed significantly lower rates of false memories than healthy controls, using the Deese–Roediger–McDermott (DRM) experimental procedure. Given that this result could be explained by the practically null rate of true recognition in the LBD group (0.09), we decided to replicate the study by de Boysson et al. (2011), but including a new condition that would maximize the true recognition rate (and analyze its effect on the rate of false memories). Specifically, in a DRM experiment, we manipulated (within subjects) two study and recognition conditions: in the “immediate” condition, both the LBD patients and the control group of healthy older people received a different recognition test after each study list (containing twelve words associated with a non‐presented critical word), while in the “delayed” condition (similar to the one in de Boysson et al., 2011), the participants received the entire series of study lists and then took only one recognition test. The results showed that, in both samples, the “immediate” condition produced higher corrected rates of both true and false recognition than the “delayed” condition, although they were both lower in the LBD patients, which shows that these patients are capable of encoding and recognizing the general similitude underlying information (gist memory) in the right conditions.     

The impact of culture on physiological processes of emotion regulation: a comparison of US and Chinese preschoolers

Cognitive determinants of emotion regulation, such as effortful control, have been hypothesized to modulate young children's physiological response to emotional stress. It is unknown, however, whether this model of emotion regulation generalizes across Western and non‐Western cultures. The current study examined the relation between both behavioral and questionnaire measures of effortful control and densely sampled, stress‐induced cortisol trajectories in U.S. and Chinese preschoolers. Participants were 3‐ to 5‐ year‐old children recruited from the United States (N = 57) and Beijing, China (N = 60). Consistent with our hypothesis, U.S. children showed a significant negative relation between maternal‐rated inhibitory control and both cortisol reactivity and recovery. However, this was not replicated in the Chinese sample. Children in China showed a significant positive relation between maternal‐rated attentional focusing and cortisol reactivity that was not seen in the U.S. Results suggest that children who reside in Western and non‐Western cultures have different predictors of their emotion‐related stress response.     

Is there an optimal factor structure of the Positive and Negative Syndrome Scale in patients with first‐episode psychosis?

The Positive and Negative Syndrome Scale (PANSS) is the most widely used scale to assess a variety of symptoms in patients with schizophrenia and other psychoses. The factor structure of the PANSS has been examined with confirmatory factor analyses in several studies, but not in a well‐defined first‐episode psychosis sample. The aim of this paper is to examine the statistical fit of five different PANSS models in a first‐episode, non‐affective psychosis sample. Confirmatory factor analyses were performed on PANSS data (n = 588). A main criterion for best fit was defined as the Expected Cross Validation Index (ECVI). No tested model revealed an optimally satisfactory model fit index. The Wallwork/Fortgang five‐factor model demonstrated the most optimal psychometric properties. The corresponding subscales of all evaluated five‐factor models were strongly intercorrelated. The Wallwork/Fortgang five‐factor model was found to be statistically and clinically ideal among patients with first‐episode psychosis. Therefore, we recommend this model in forthcoming studies among patients with first‐episode psychosis. However, to prevent the loss of clinically valuable information on an item level, we do not recommend removing any items from the original form. Our study also implies that the specific choice of model will not have a substantial effect on outcome results in studies on the course and outcome in first‐episode psychosis.     

The structure of effortful control in preschoolers and its relation to externalizing problems

The first aim of the present study was to examine the structure of effortful control. The second aim was to determine whether components of effortful control relate to conduct problems and hyperactivity. Effortful control was measured in 3‐year‐old children (N= 89) with an observational measure, the effortful control battery (ECB), and a parent report, the Children's Behaviour Questionnaire (CBQ). Principal component analysis showed that the ECB measures five components, assessing two higher‐order constructs, which can be labelled as Self‐Control and Attention/Motor Control. The five scales of the CBQ appeared to measure one construct – a more general measure of effortful control. The components and constructs of the ECB as well as the scales of the CBQ were differently related to conduct problems and hyperactivity. Conduct problems were most strongly predicted by observed Delay of Gratification and parent‐reported Inhibitory Control, whereas Hyperactivity was most strongly predicted by observed Delay of Gratification, and the higher‐order construct Attention/Motor Control, as well as parent‐reported Attentional Focusing and Inhibitory Control. It is important to keep in mind that effortful control is composed of heterogeneous components, all having their own unique values.     

Information processing and aspects of visual attention in children with the DSM-III-R diagnosis “pervasive developmental disorder not otherwise specified” (PDDNOS): II. sustained attention

A group of 15 nonhyperactive children of normal intelligence with the DSM-III-R diagnosis “pervasive developmental disorder not otherwise specified” (PDDNOS) performed a sustained attention task. Adopting a cognitive-energetical linear stage model of human information processing, we investigated whether task performances deteriorated due to a diminishing level of arousal, activation, or by the active ‘effortful’ mode of information processing. In comparison to an age-matched group of normal children, the patients showed no sharper decrease in perceptual sensitivity (d'). D' is assumed to be a measure of arousal. However, the children with PDDNOS exhibited large fluctuations in their response bias beta (β), which is assumed to be a measure of activation. During the first part of the task, they shifted between under- and overestimating negative responses. In the latter part of the task this pattern altered to significantly overestimating the number of negative responses. This indicates that the patients were not able to appropriately tune to the task-inherent response probability. Moreover, as compared to the control children, the patients showed a significantly sharper decrease in hit rate with time on task, despite the fact that feedback was given on the errors. The findings are interpreted as an increasing loss of the ability to control the response bias due to difficulties in maintaining the voluntary effortful mode of processing information with prolonged time on task.     

Attentional Processing of Threat in Bipolar Disorder: Going Beyond Mood-Congruency

Emotional processing in bipolar disorder (BD) entails a complex attentional pattern not merely restricted to happy or sad biases, but also directed towards threatening information. This study examined threat-related bias on attentional orienting when participants were not instructed about the presentation of emotional stimuli (i.e., implicit instructions). An emotional dot-probe task in which an emotional face (i.e., threat, sad, happy) is simultaneously displayed with a neutral face was applied to BD individuals in their different episodes: mania (n?=?26), depression (n?=?24), and euthymia (n?=?28) as well as to a group of healthy controls (n?=?28). Symptomatic BD patients (i.e., in a manic or depressive episode) showed an attentional orienting bias toward threatening faces but not for happy or sad faces, while euthymic BD patients did not exhibit any attentional bias for emotional stimuli. A bias toward happy faces was found in the control group. Threat-related bias was not related to the severity of affective and anxiety symptoms in BD. When attention is not explicitly directed to emotional information, threat-related bias may characterize attentional orienting during mania and depression, but may be attenuated during euthymia.

     

Cognitive functioning and cortisol profiles in first episode major depression

Major Depressive Disorder (MDD) is often associated with high levels of stress and disturbances in the Hypothalamic Pituitary Adrenal (HPA) system, yielding high levels of cortisol, in addition to cognitive dysfunction. Previous studies have shown a relationship between cortisol profile and cognitive functioning in recurrent MDD in general. More specifically, the association between hypercortisolism and cognitive functioning, such as memory and Executive Functioning (EF), and also more recently cortisol suppression has been explored. However, no studies have investigated these relationships in patients diagnosed with first episode MDD. The aim of the present study was to examine the relationship between cortisol levels before and after the Dexamethasone suppression test (DST) and cognitive function in first episode MDD patients. Twenty‐one patients meeting the DSM‐IV criteria for a first episode of MDD diagnosis were included in the study. The control group was matched for age, gender and education level. Cortisol was measured in saliva collected with Salivette sampling devices. Saliva samples were collected 4 times during a 24 hours period over two consecutive days: at awakening, after 45 minutes, after 7 hours and at 11 pm. Dexamethasone (1.0 mg) was given orally on Day 1 at 11 pm. The neuropsychological test battery consisted of standardized tests measuring executive functioning (EF) and memory functioning. Cortisol levels did not differ significantly between patients and controls on Day 1, except for the last sample before Dexamethasone administration, where the control group showed higher levels. Both groups showed suppression after Dexamethasone. On Day 2 there was a significant difference between groups at the third sample, showing a significantly lower level in the control group, suggesting that the controls have a more effective suppression profile than the patients. There were no significant correlations between cortisol levels before or after Dexamethasone and cognitive measures. The results indicate impairment on HPA‐axis functioning in first episode MDD patients, with less suppression functioning compared to healthy controls, but no relationship between cortisol profile and cognitive functioning in EF or Memory.     

The perception of biological and mechanical motion in female fragile X premutation carriers

Previous studies reported impaired visual information processing in patients with fragile X syndrome and in premutation carriers. In this study, we assessed the perception of biological motion (a walking point-light character) and mechanical motion (a rotating shape) in 25 female fragile X premutation carriers and in 20 healthy non-carrier controls. Stimuli were moving stimulus dots embedded among a cloud of noise dots. Sensitivity (d′) for motion detection was determined. Emotional symptoms were assessed by Hamilton’s depression and anxiety rating scales. Results revealed that the premutation carriers displayed lower sensitivities for biological and mechanical motion relative to the non-carriers. This deficit was more pronounced in the case of biological stimuli. The premutation carriers displayed higher depression and anxiety scores relative to the non-carriers. Higher depression, but not anxiety, scores were associated with decreased sensitivity for biological, but not mechanical, motion in the carrier group. These results suggest that motion perception deficits are detectable in fragile X premutation carriers, and that the impairment of biological motion perception is associated with depressive symptoms.     

Reasoning and dyslexia: A spatial strategy may impede reasoning with visually rich information

Bacon, Handley and Newstead (2003, 2004) , have presented evidence for individual differences in reasoning strategies, with most people seeming to represent and manipulate problem information using either a verbal or a spatial strategy. There is also evidence that individuals with dyslexia are inclined to conceptualise information in a visuo‐spatial, rather than a verbal, way (e.g. von Károlyi et al., 2003 ). If so, we might expect a higher proportion of individuals with dyslexia to be spatial reasoners, compared with individuals who do not have dyslexia. The study reported here directly compared strategies reported by these two groups of participants on a syllogistic reasoning task. Moreover, problem content was manipulated so that reasoning across concrete and abstract materials could be compared. The findings suggest that whilst most individuals without dyslexia use a verbal strategy, reasoners with dyslexia do tend to adopt a spatial approach, though their performance is impaired with visually concrete materials. However, when reasoning with more abstract content, they perform comparably with non‐dyslexic controls. The paper discusses these results in the light of recent research which has suggested that visual images may impede reasoning, and considers how individuals with dyslexia may differ from other reasoners.     

Elaborative processing in the Korsakoff syndrome: context versus habit

Using a procedure of Hay and Jacoby [Hay, J. F., & Jacoby, L. L. (1999). Separating habit and recollection in young and older adults: Effects of elaborative processing and distinctiveness. Psychology and Aging, 14, 122–134], Korsakoff patients’ capacity to encode and retrieve elaborative, semantic information was investigated. Habits were created during initial training, whereupon cued-recall memory performance was examined, with habit opposing as well as facilitating recollection of earlier studied words. A first group of patients was instructed and tested in the same way as healthy controls and showed poor test performance. Nevertheless, when given more processing and response time, additional explanation, and explicit encouragement, a second group of patients performed similarly to healthy controls. The results suggest that, when given adequate support, Korsakoff patients are able to encode and make use of semantic, contextual, and sequential information. Word distinctiveness, however, only influenced performance of controls.     

Mood-induced changes on the Implicit Association Test in recovered depressed patients

A mood induction paradigm was used to examine dysphoria-related changes in two types of cognitive processing in individuals who had previously experienced depression. Formerly depressed patients (n = 23) and never-depressed controls (n = 27) completed the Dysfunctional Attitudes Scale, a self-report measure of effortful processing, and performed the Implicit Association Test, an automatic-reaction time task that measures evaluative bias, before and after a negative-mood induction. The formerly depressed group showed both an increase in endorsement of dysfunctional attitudes and a more negative evaluative bias for self-relevant information after the induction, relative to controls--however, there was no association between the mood-linked changes observed on these two measures. The shift in evaluative bias shown by the formerly depressed group was similar to that seen in a group of 32 currently depressed individuals. These findings suggest that even a mild negative mood in formerly depressed individuals can reinstate some of the cognitive features observed in depression itself.