Computational cognitive modeling of the temporal dynamics of fatigue from sleep loss

Computational models have become common tools in psychology. They provide quantitative instantiations of theories that seek to explain the functioning of the human mind. In this paper, we focus on identifying deep theoretical similarities between two very different models. Both models are concerned with how fatigue from sleep loss impacts cognitive processing. The first is based on the diffusion model and posits that fatigue decreases the drift rate of the diffusion process. The second is based on the Adaptive Control of Thought – Rational (ACT-R) cognitive architecture and posits that fatigue decreases the utility of candidate actions leading to microlapses in cognitive processing. A biomathematical model of fatigue is used to control drift rate in the first account and utility in the second. We investigated the predicted response time distributions of these two integrated computational cognitive models for performance on a psychomotor vigilance test under conditions of total sleep deprivation, simulated shift work, and sustained sleep restriction. The models generated equivalent predictions of response time distributions with excellent goodness-of-fit to the human data. More importantly, although the accounts involve different modeling approaches and levels of abstraction, they represent the effects of fatigue in a functionally equivalent way: in both, fatigue decreases the signal-to-noise ratio in decision processes and decreases response inhibition. This convergence suggests that sleep loss impairs psychomotor vigilance performance through degradation of the quality of cognitive processing, which provides a foundation for systematic investigation of the effects of sleep loss on other aspects of cognition. Our findings illustrate the value of treating different modeling formalisms as vehicles for discovery.     

The validity of psychomotor vigilance tasks of less than 10-minute duration.

The 10-min psychomotor vigilance task (PVT) has often been used to assess the impact of sleep loss on performance. Due to time constraints, however, regular testing may not be practical in field studies. The aim of the present study was to examine the suitability of tests shorter than 10 min. in duration. Changes in performance across a night of sustained wakefulness were compared during a standard 10-min PVT, the first 5 min of the PVT, and the first 2 min of the PVT. Four performance metrics were assessed: (1) mean reaction time (RT), (2) fastest 10% of RT, (3) lapse percentage, and (4) slowest 10% of RT. Performance during the 10-min PVT significantly deteriorated with increasing wakefulness for all metrics. Performance during the first 5 min and the first 2 min of the PVT deteriorated in a manner similar to that observed for the whole 10-min task, with all metrics except lapse percentage displaying significant impairment across the night. However, the shorter the task sampling time, the less sensitive the test is to sleepiness. Nevertheless, the 5-min PVT may provide a viable alternative to the 10-min PVT for some performance metrics.     

The validity of psychomotor vigilance tasks of less than 10-minute duration

The 10-min psychomotor vigilance task (PVT) has often been used to assess the impact of sleep loss on performance. Due to time constraints, however, regular testing may not be practical in field studies. The aim of the present study was to examine the suitability of tests shorter than 10 min. in duration. Changes in performance across a night of sustained wakefulness were compared during a standard 10-min PVT, the first 5 min of the PVT, and the first 2 min of the PVT. Four performance metrics were assessed: (1) mean reaction time (RT), (2) fastest 10% of RT, (3) lapse percentage, and (4) slowest 10% of RT. Performance during the 10-min PVT significantly deteriorated with increasing wakefulness for all metrics. Performance during the first 5 min and the first 2 min of the PVT deteriorated in a manner similar to that observed for the whole 10-min task, with all metrics except lapse percentage displaying significant impairment across the night. However, the shorter the task sampling time, the less sensitive the test is to sleepiness. Nevertheless, the 5-min PVT may provide a viable alternative to the 10-min PVT for some performance metrics.     

Effects of sleep deprivation on executive functioning,cognitive abilities,metacognitive confidence,and decision making

Performance on many decision‐making tasks is underpinned by metacognitive monitoring, cognitive abilities, and executive functioning. Fatigue‐inducing conditions, such as sleep loss, compromise these factors, leading to decline in decision performance. Using a 40‐hr sleep deprivation protocol, we examined these factors and the resulting decision performance. Thirteen Australian Army male volunteers (aged 20–30 years) were tested at multiple time points on psychomotor vigilance, inhibitory control, task switching, working memory, short‐term memory, fluid intelligence, and decision accuracy and confidence in a medical diagnosis‐making test. Assessment took place in the morning and night over two consecutive days, during which participants were kept awake. Consistent with previous work, cognitive performance declined after a night without sleep. Extending previous findings, self‐regulation and self‐monitoring suffered significantly greater declines immediately after the sleepless night. These results indicate that the known decline in complex decision‐making performance under fatigue‐inducing conditions might be facilitated by metacognitive rather than cognitive mechanisms.     

Sleep deprivation and sustained attention performance: integrating mathematical and cognitive modeling

A long history of research has revealed many neurophysiological changes and concomitant behavioral impacts of sleep deprivation, sleep restriction, and circadian rhythms. Little research, however, has been conducted in the area of computational cognitive modeling to understand the information processing mechanisms through which neurobehavioral factors operate to produce degradations in human performance. Our approach to understanding this relationship is to link predictions of overall cognitive functioning, or alertness, from existing biomathematical models to information processing parameters in a cognitive architecture, leveraging the strengths from each to develop a more comprehensive explanation. The integration of these methodologies is used to account for changes in human performance on a sustained attention task across 88 h of total sleep deprivation. The integrated model captures changes due to time awake and circadian rhythms, and it also provides an account for underlying changes in the cognitive processes that give rise to those effects. The results show the potential for developing mechanistic accounts of how fatigue impacts cognition, and they illustrate the increased explanatory power that is possible by combining theoretical insights from multiple methodologies.     

The effects of changing the phase and duration of sleep.

The relative effects of extended sleep, reduced sleep, and shifts of habitual sleep time on subsequent performance and mood were studied. Ten healthy male university students who regularly sleep 9.5-10.5 hr were the subjects. Measurements were obtained from a 45-min auditory vigilance task, a 5-min experimenter-paced addition task and a mood adjective check list 30 min after awakening, at midday, and in the evening following five electroencephalographically recorded nights of sleep. The experimental treatments compromised at 9.5-10.5 hr habitual sleep condition and four conditions in which the regular sleep period was lengthened, reduced, delayed, and advanced by 3hr. Following each 3-hr altered condition of sleep there was an equivalent decline in vigilance performance and in subjective arousal as measured by the mood scales. Together with other recent evidence, the present results support the hypothesis that acute disruption of the 24-hr sleep-wakefulness cycle produces degradations in human performance largely independent of total sleep time.     

黎明模拟光照对晨起睡眠惰性的影响

本研究采用单因素被试内设计对清晨唤醒后睡眠惰性对个体主观情绪、警觉性和认知加工的影响，以及利用动态黎明模拟光照能否对睡眠惰性产生有效的对抗作用进行了考察。结果发现：（1）被试的积极情绪、主观警觉性在刚唤醒时显著低于基线水平，之后随时间推移逐渐提升。（2）被试醒后立即进行测试的认知加工成绩最差，随后逐渐提高，且主要表现在加工速度的回升上。（3）黎明模拟光照对被试醒后在积极情绪、主观警觉性、持续性注意和抑制功能的缓解上产生了明显的促进作用。这表明睡眠惰性会对个体的主客观活动产生显著的负性影响，而使用黎明模拟光照可在一定程度上对抗睡眠惰性带来的负性影响。     

The Effects of Eight-Month Physical Activity Intervention on Vigilance Performance in Adult Obese Population

We aim to analyze the effects of an 8-month physical activity intervention on cardiorespiratory fitness, body mass index (BMI), and vigilance performance in an adult obese population. We conducted an 8-month physical activity intervention based on dance and rhythmic activities. The weekly frequency was 2 sessions of 1 hr per day. Training sessions were divided into 3 phases: a 10-min warm-up, 40 min of dance and rhythmic activities, and 10 min to cool-down. To assess cardiorespiratory fitness, participants performed a modified version of the 6-min walk test from the Senior Fitness Test battery (Larsson & Mattsson, 2001; Rikli & Jones, 1999). Vigilance performance was measured by means of the psychomotor vigilance task (PVT). Two measurements were performed immediately before and after the intervention. The results revealed that participants improved their cardiorespiratory fitness, BMI, and vigilance performance after the intervention. All in all, findings contribute new empirical evidence to the field that investigates the benefits of physical activity intervention on cognitive processes in obese population.     

Further Evidence That Sleep Deprivation Effects and the Vigilance Decrement Are Functionally Equivalent: Comment on Altmann (2018)

Veksler and Gunzelmann (2018) argue that the vigilance decrement and the deleterious effects of sleep loss reflect functionally equivalent degradations in cognitive processing and performance. Our account is implemented in a cognitive architecture, where these factors produce breakdowns in goal‐directed cognitive processing that we refer to as microlapses. Altmann (2018) raises a number of challenges to microlapses as a unified account of these deficits. Under scrutiny, however, the challenges do little to discredit the theory or conclusions in the original paper. In our response, we address the most serious challenges. In so doing, we provide additional support for the theory and mechanisms, and we highlight opportunities for extending their explanatory breadth.     

Effects of task duration on sensitivity to sleep deprivation using the multi-attribute task battery

Several factors affect the sensitivity to sleep deprivation in the performance of computerized tests. Two of these are task complexity and duration. Complexity can improve sensitivity by increasing the demands required to complete the task, but it can also decrease sensitivity by improving the subject’s motivation. The effects of task duration are more predictable in that longer tests generally are more susceptible to deprivation effects than shorter ones. The impact of task duration on an interesting, but complex, aviation simulation was examined here. By breaking down data from 30-min multi-attribute task battery administrations into the first, second, and third 10 min of performance, it was shown that tests shorter than 30 min underestimate the impact of sleep loss on performance. This was especially evident in measures of time-out and tracking errors.     

Towards a new approach to detect sleepiness: Validation of the objective sleepiness scale under simulated driving conditions

The Objective Sleepiness Scale (OSS) was developed to detect and quantify sleepiness on the basis of two direct and reliable sleepiness indicators: EEG and EOG. The present study aims to test whether the OSS can be used to detect sleepiness episodes that impair performance on driving and vigilance tasks accurately and with a good time synchronization. Forty-three healthy volunteers performed monotonous driving sessions on a simulator and the psychomotor vigilance task (PVT) in a normal sleep condition and after partial sleep deprivation. OSS reliability and time synchronization for sleepiness detection were tested on driving (standard deviation of vehicle lateral position and off-road duration) and PVT (reaction time and lapses). Inter-rater reliability of the scale was evaluated by two blinded scorers. Results show that the OSS score indicates higher sleepiness in sleep deprivation conditions (p < 0.001) and with time-on-task. Differences of performance between OSS score calculated with multiple pairwise comparisons, indicate OSS score increase when driving performance (SDLP and off-road duration) decreases (p < 0.001 for comparisons between OSS stages 0 vs 2, 0 vs 3, 1 vs 2 and p < 0.05 for 1 vs 3). Reaction time during PVT is also related to the OSS score (p < 0.05 for OSS values from 0 to 2, 0 to 3, 1 to 2 and 1 to 3). There is no proportional relation between OSS score and performance impairment, but a threshold effect between levels 1 and 2 of the scale is observed. Positive outcomes are also obtained for time synchronization of the OSS assessed on driving performance (p < 0.001 for both SDLP and off-road duration). Finally, inter-rater agreement is found to be considerable. The results allow us to consider using the Objective Sleepiness Scale as a tool for research on sleepiness.     

Does Absence of Hearing Ability Enhance Visual Vigilance? It Depends on Task Complexity

Successful performance of a vigilance task in a particular modality can be affected by the allocation of attentional resources to other cognitive processes using same or different modalities. The present study investigated whether loss of hearing affects visual vigilance task performance and also if it’s a function of increased task complexity. A sample of 30 adolescents ( 15 with hearing loss and 15 with normal hearing) were selected by matching them in pairs according to their working memory functioning and other relevant organismic variables. A software program measured the performance on vigilance task with varying task complexity levels. Analysis of the obtained data indicates that the effect of hearing impairment on visual vigilance is moderated by task complexity and that is contingent to attentional resources. Here, deprivation in hearing ability negatively affects functioning of visual vigilance significantly only when the task complexity increases. But no significant differences are observed in hearing and hearing impaired adolescents when the task demanded less attentional resources.     

Reversible Verbal Memory Integration Deficits in Obstructive Sleep Apnoea

When presented with novel but semantically related elements after learning verbal material, healthy participants tend to endorse these items as previously learned. This reflects the normal integration and association of novel verbal information into long-term memory. How obstructive sleep apnoea (OSA) negatively impacts verbal memory performance, and whether deficits are reversible following positive airway pressure (PAP) treatment, remain elusive. We investigated immediate and delayed OSA- and PAP treatment-related effects on verbal memory integration, using a false memory paradigm. Twenty-three patients with OSA learned lists of words semantically related to target non-presented words (1) at baseline after a polysomnography diagnosis night, (2) after a consecutive polysomnography night under PAP titration, and (3) after three months of compliant PAP treatment. At each session, participants learned 10 different lists of words, each list comprising 15 semantically related items. They had then to recognize 15 minutes later (after an intermediate vigilance task) previously learned words within a list including studied words (learned), unstudied but semantically related items (lures), and non-related unstudied items (controls). Sleep quality and fatigue questionnaires, and psychomotor vigilance tests (PVT) were administered at each session. PAP treatment led to OSA remission and improvement in objective and subjective sleep quality. Crucially, recognition of learned and lure words increased after the first night under treatment and remained stable three months later, suggesting successful memory integration and restoration of semantic processes. No treatment-related outcome was found on PVT performance. OSA exerts a detrimental but PAP-reversible effect on verbal learning and semantic memory integration mechanisms underlying the acquisition of novel memory representations.     

Comparing the Effects of Three Cognitive Tasks on Indicators of Mental Fatigue

Abstract

This investigation assessed the impact of three cognitively demanding tasks on cognitive performance, subjective, and physiological indicators of mental fatigue. Following familiarization, participants completed four testing sessions, separated by 48?h. During each session, participants watched a 45-min emotionally neutral documentary (control) or completed one of the following computer tasks: Psychomotor Vigilance Task (PVT); AX-Continuous Performance Test (AX-CPT); or Stroop Task. Mental fatigue was assessed before and at regular periods for 60?min following the 45-min treatments. Cognitive performance was assessed using 3-min PVT, and task performance. Subjective assessments were conducted using the Brunel Mood Scale, and visual analog scales (VAS). Physiological indicators of mental fatigue included electroencephalography (EEG), and heart rate variability (HRV). Subjective ratings of mental fatigue increased from pre to 0-min post in all-treatments, but not the documentary (p?p?相似文献   

No Evidence That Sleep Deprivation Effects and the Vigilance Decrement Are Functionally Equivalent: Comment on Veksler and Gunzelmann (2017)

Veksler and Gunzelmann (2017) make an extraordinary claim, which is that sleep deprivation effects and the vigilance decrement are functionally equivalent. Extraordinary claims require extraordinary evidence, which is missing from Veksler and Gunzelmann's study. Their behavioral data offer only weak theoretical constraint, and to the extent their modeling exercise supports any position, it is that these two performance impairments involve functionally distinct underlying mechanisms.     

3-minute smartphone-based and tablet-based psychomotor vigilance tests for the assessment of reduced alertness due to sleep deprivation

The psychomotor vigilance test (PVT) is widely used to measure reduced alertness due to sleep loss. Here, two newly developed, 3-min versions of the psychomotor vigilance test, one smartphone-based and the other tablet-based, were validated against a conventional 10-min laptop-based PVT. Sixteen healthy participants (ages 22–40; seven males, nine females) completed a laboratory study, which included a practice and a baseline day, a 38-h total sleep deprivation (TSD) period, and a recovery day, during which they performed the three different versions of the PVT every 3 h. For each version of the PVT, the number of lapses, mean response time (RT), and number of false starts showed statistically significant changes across the sleep deprivation and recovery days. The number of lapses on the laptop was significantly correlated with the numbers of lapses on the smartphone and tablet. The mean RTs were generally faster on the smartphone and tablet than on the laptop. All three versions of the PVT exhibited a time-on-task effect in RTs, modulated by time awake and time of day. False starts were relatively rare on all three PVTs. For the number of lapses, the effect sizes across 38 h of TSD were large for the laptop PVT and medium for the smartphone and tablet PVTs. These results indicate that the 3-min smartphone and tablet PVTs are valid instruments for measuring reduced alertness due to sleep deprivation and restored alertness following recovery sleep. The results also indicate that the loss of sensitivity on the 3-min PVTs may be mitigated by modifying the threshold defining lapses.     

Effects of test anxiety, tests, and sleep on children''s performance

This study examined the interrelationship between children's test anxiety, sleep, and performance. The subjects, 239 sixth and seventh graders, responded to questionnaires examining sleep behavior and test anxiety on a day when they had a major exam in school, and on a day when they did not. They also completed a vigilance task on both days. The results showed that partial sleep loss (i.e., under 3 hr) did not adversely influence subjects' performance on the vigilance task or on the actual class exam. However, the results did reveal that test anxiety was negatively related to performance on the class exam.     

在不同事件率条件下人格倾向类型对认知性警戒的影响

本研究采用两种事件率 ,考察了人格倾向类型对认知性警戒的影响。实验结果表明 :(1 )事件率是影响作业绩效的一个重要因素。事件率与人格倾向存在着交互作用。 (2 )认知性警戒作业的应激效应与事件率有关 ,随着事件率的上升 ,受试者在作业过程中的应激水平明显增高。 (3 )根据对被试自觉疲劳的测量结果 ,在认知性警戒作业中 ,内倾者与外倾者间应激水平存在差异。     

Lack of degradation in visuospatial perception of line orientation after one night of sleep loss

Sleep deprivation impairs a variety of cognitive abilities including vigilance, attention, and executive function. Although sleep loss has been shown to impair tasks requiring visual attention and spatial perception, it is not clear whether these deficits are exclusively a function of reduced attention and vigilance or if there are also alterations in visuospatial perception. Visuospatial perception and sustained vigilance performance were therefore examined in 54 healthy volunteers at rested baseline and again after one night of sleep deprivation using the Judgment of Line Orientation Test and a computerized test of psychomotor vigilance. Whereas psychomotor vigilance declined significantly from baseline to sleep-deprived testing, scores on the Judgment of Line Orientation did not change significantly. Results suggest that documented performance deficits associated with sleep loss are unlikely to be the result of dysfunction within systems of the brain responsible for simple visuospatial perception and processing of line angles.     

The impact of cognitive interference on performance during prolonged sleep loss

Summary A study was conducted on the effects of off-task cognitions on performance during sleep deprivation. Subjects answered the Thought Occurrence Questionnaire, assessing their proneness to engage in off-task cognitions, and were deprived of sleep for 72 hours, during which they performed a variety of tasks including visual discrimination and three versions of a logical reasoning task in which cognitive load was varied systematically. In addition, every day subjects answered the Cognitive Interference Questionnaire, which taps off-task cognitions during the experiment. Results indicated that subjects who habitually engage in off-task cognitions performed worse during 72 hours of sleep loss than subjects who do not engage in such distracting activities. In addition, it was found that the engagement in off-task cognitions increased during the 72 hours of sleep loss and such an engagement was related to deficits in performance accuracy. The mechanisms of off-task cognitions and sleep loss underlying these effects are discussed.