The role of controlled attention on recall in major depression

Information processing biases are hallmark features of major depressive disorder (MDD). Depressed individuals display biased memory and attention for negative material. Given that memory is highly dependent on attention for initial encoding, understanding the interplay of these processes may provide important insight into mechanisms that produce memory biases in depression. In particular, attentional control—the ability to selectively attend to task-relevant information by both inhibiting the processing of irrelevant information and disengaging attention from irrelevant material—may be one area of impairment in MDD. In the current study, clinically depressed (MDD: n = 15) and never depressed (non-MDD: n = 22) participants' line of visual gaze was assessed while participants viewed positive and negative word pairs. For each word pair, participants were instructed to attend to one word (target) and ignore one word (distracter). Free recall of study stimuli was then assessed. Depressed individuals displayed greater recall of negatively valenced target words following the task. Although there were no group differences in attentional control in the context of negative words, attention to negative targets mediated the relationship between depression status and recall of negative words. Results suggest a stronger link between attention and memory for negative material in MDD.     

阈下抑郁个体对负性情绪刺激的注意解脱困难

本研究拟采用点探测范式及不同情绪内容的面孔刺激（高兴、中性、悲伤和愤怒）考察阈下抑郁个体的负性注意偏向及其内在机制。点探测任务中情绪面孔配对呈现（负性-中性、正性-中性）,配对面孔中的情绪线索位置与靶刺激的位置构成负性一致/不一致和正性一致/不一致条件,同时实验中加入“中性-中性”面孔线索作为一致和不一致条件的对比基线来考察注意偏向的内在机制。结果发现,阈下抑郁个体在负性不一致条件下的反应时显著长于负性一致条件,表明阈下抑郁个体具有对负性刺激的注意偏向;进一步比较发现,阈下抑郁个体在负性不一致条件下的反应时显著的长于“中性-中性”基线条件,而负性一致条件与基线之间差异不显著,表明阈下抑郁个体的负性注意偏向为对负性刺激的注意解脱困难。结果另发现,阈下抑郁个体未能像无抑郁对照组个体表现出对正性刺激的注意偏向。结果表明,处于阈下抑郁状态的个体表现出对负性刺激的注意偏向,具体为对负性刺激的注意解脱困难,其原因可能是由于阈下抑郁个体在注意控制和情绪调节功能上的紊乱。     

Attentional Processing of Threat in Bipolar Disorder: Going Beyond Mood-Congruency

Emotional processing in bipolar disorder (BD) entails a complex attentional pattern not merely restricted to happy or sad biases, but also directed towards threatening information. This study examined threat-related bias on attentional orienting when participants were not instructed about the presentation of emotional stimuli (i.e., implicit instructions). An emotional dot-probe task in which an emotional face (i.e., threat, sad, happy) is simultaneously displayed with a neutral face was applied to BD individuals in their different episodes: mania (n?=?26), depression (n?=?24), and euthymia (n?=?28) as well as to a group of healthy controls (n?=?28). Symptomatic BD patients (i.e., in a manic or depressive episode) showed an attentional orienting bias toward threatening faces but not for happy or sad faces, while euthymic BD patients did not exhibit any attentional bias for emotional stimuli. A bias toward happy faces was found in the control group. Threat-related bias was not related to the severity of affective and anxiety symptoms in BD. When attention is not explicitly directed to emotional information, threat-related bias may characterize attentional orienting during mania and depression, but may be attenuated during euthymia.

     

Suppressing and attending to pain-related thoughts in chronic pain patients

Attempted suppression of pain-related thoughts was investigated in consecutive referrals for pain management (N = 39). Participants monitored their pain-related thoughts for three 5-min periods. In period 1, all participants were instructed to think about anything. For period 2, participants were instructed to either suppress pain-related thoughts, attend to pain-related thoughts, or to continue to think about anything. In period 3, all participants were again instructed to think about anything. Participants instructed to attend to their pain reported more pain-related thoughts than suppressors and controls in both periods 2 and 3. Suppressors experienced reduced pain-related thoughts during period 2. There was no immediate enhancement or delayed increase.     

The effects of attention retraining on depressive mood and cortisol responses to depression‐related stimuli1

Although it has been reported that attentional bias at an early stage is found in depression, no study has investigated the effects of modification of attentional bias at an early stage on depressive mood and cortisol response to a stressor. Therefore, this study tested the hypotheses that the modification of attentional bias at an early stage would reduce depressive mood and cortisol response. Fifty‐three participants were allocated alternately either to the training or the control group. They were administered attention retraining for modification of attentional bias or a sham attention task, and then underwent a stress task. With respect to depressive mood response, depressive mood increased in response to a stress task in the control group, while for high‐dysphoric participants in the training group, depressive mood response remained constant. These results indicate that attention retraining is efficacious for reducing depressive mood response. With respect to cortisol response, the percentage change in cortisol is associated with the amount of change in the attentional bias index scores. The results suggest the possibility that attention retraining could reduce cortisol response.     

Depressive symptoms are associated with unrealistic negative predictions of future life events

This study examined the relationship between depressive symptoms and bias in the prediction of future life events. Responding to internet announcements, 153 participants varying widely in self-reported depression symptom severity estimated the probability of 40 events occurring over the succeeding 30 days. After the 30-day period, participants reported which events occurred. Optimistic/pessimistic biases were related to level of depressive symptoms. A non-significant optimistic bias characterized participants with low depressive symptoms whereas a significant pessimistic bias characterized participants with high depressive symptoms. Those reporting mild symptoms did not exhibit a systematic pessimistic or optimistic bias. General imprecision in predictions for undesirable events was associated with depressive symptoms. These findings suggest that depression is associated with pessimistic bias rather than accuracy in judgment.     

Brooding rumination and attentional biases in currently non-depressed individuals: an eye-tracking study

Both rumination and attentional biases have been proposed as key components of the RDoC Negative Valence Systems construct of Loss. Although theorists have proposed that rumination, particularly brooding rumination, should be associated with increased sustained attention to depression-relevant information, it is not clear whether this link would be observed in a non-depressed sample or whether it is specific to brooding versus reflective rumination. To address these questions, the current study examined the link between brooding rumination and attentional biases in a sample of non-depressed individuals (n?=?105). Attentional biases were assessed using eye tracking during a passive viewing task in which participants were presented with 2?×?2 arrays of angry, happy, sad, and neutral faces. In line with predictions, higher levels of brooding rumination were associated with greater sustained attention to sad faces and less sustained attention to happy faces. These results remained significant after controlling for participants’ prior history of major depression and current nonclinical level of depressive symptoms, suggesting that the link between brooding rumination and attentional biases is at least partially independent of current or past depression.     

How falsity dispels fallacies

From certain sorts of premise, individuals reliably infer invalid conclusions. Two Experiments investigated a possible cause for these illusory inference: Reasoners fail to think about what is false. In Experiment 1, 24 undergraduates drew illusory and control inferences from premises based on exclusive disjunctions (“or else”). In one block, participants were instructed to falsify the premises of each illusory and control inference before making the inference. In the other block, participants did not receive these instructions. There were more correct answers for illusory disjunctions whose premises had been falsified than there were for illusory disjunctions that had not been falsified. A second Experiment introduced illusory inferences in a real world context that accentuated falsification of premises. Accuracy also improved. Knowledge of how to falsify premises and to consider their implications for true premises transferred to a new problem introduced at the end of the Experiment without the falsification instruction. The participants' ratings of the difficulty of the inferences showed that they did not err simply because illusory inferences are perceived to be more difficult than control problems. The model theory predicts these results because it postulates that the limitations of working memory preclude the representation of false information.     

Depressive realism and attributional style: implications for individuals at risk for depression

Prior research has found that depressed individuals are more realistic in their interpretations of certain events than nondepressed individuals. However, the implications of this finding for the etiology of depressive disorders have never been clarified. The current investigation sought to remedy this situation by exploring realism in the context of a well-validated, cognitive diathesis-stress theory of the etiology of a subtype of depression: hopelessness theory (Abramson, L. Y., Metalsky, G. I., & Alloy, L. B. (1989). Hopelessness depression: A theory-based subtype of depression. Psychological Review, 96, 358-372). A sample of 239 college students, including groups of participants with depressogenic versus nondepressogenic attributional styles, recorded the causes they assigned to events; the extent to which their attributions were objectively realistic was evaluated. A comparison of the degree of objectivity was also made between dysphoric and nondysphoric individuals. Contrary to expectations derived from the depressive realism hypothesis, dysphoric individuals exhibited less realistic attributions as compared to nondysphoric individuals. Further, individuals at risk for depression evidenced a pessimistic bias, while individuals not at risk evidenced an optimistic bias.     

Judgement of control revisited: Are the depressed realistic or pessimistic?

The study, firstly, examined the depressive realism postulate in relation to control judgments. A group of depressed and nondepressed undergraduates were exposed to a total of six judgement of control tasks (from 0% control tio 100% control). Depressed and nondepressed subjects did not differ in their control judgements. Secondlym, an attempt is made to classify subjects on the basis of these six judgements of control tasks as optimisticm, realistic and pessimistic in perceived control judgements.It was found that pessimistic rather than realistic subjects, had higher depressive symptomatology. Lastly, pessimism about control predicted the depressive symptomatology as assessed three months later. The results are discussed in relation to the phenomenon of depressive realism and the hopelessness theory of depression.     

Negative thoughts in depression: A study in Iran

The cognitive theory of depression proposes significant relations between negative thoughts and depression. Evidence for the model has been widely observed in Western countries. However, despite the high prevalence of depression in the Middle East (ME), there has been limited research that has evaluated the cognitive profiles of people living in this region, and especially in non-Arab countries like Iran. The current research examined these relationships in Iran. Convenience sampling was used to recruit 80 depressed and 80 non-depressed individuals via advertising in clinics and public areas, respectively. Depression status was checked with a structured interview, the Major Depressive Disorder subscale of the Psychiatric Diagnostic Screening Questionnaire, and the Beck Depression Inventory-II. All participants completed the Automatic Thoughts Questionnaire-Negative to examine the frequency of negative automatic thoughts. Unlike other results from Arab countries, depressed participants indicated significantly more negative thoughts towards self and future compared with the non-depressed group. The results of the present study are consistent with the negativity hypothesis of the cognitive theory of depression. Further research is needed in the in ME, to investigate other hypotheses of this theory in this region. Strengths and limitations of the present study are discussed.     

Cognitive control of obsessional thoughts

A defining characteristic of obsessive-compulsive disorder (OCD) is unsuccessful suppression of unwanted thoughts. Recent evidence of individual differences in ability to control intrusive thoughts may inform our understanding of failures of cognitive control associated with OCD symptomatology. The current study investigated characteristics of cognitive style that are potentially associated with OCD symptoms and may influence response to unwanted thoughts, including perceived ability to control thoughts and tendency to ruminate. Undergraduate students (N = 166) completed self-report measures of OCD symptoms, perceived thought control, and ruminative thinking. They were then presented with a distressing target thought and completed a standard thought suppression paradigm. Correlational results indicated that, controlling for anxiety and depression, OCD symptoms were positively associated with rumination and inversely associated with perceived thought control ability. In addition, OCD symptoms were associated with higher levels of distress and greater spontaneous efforts to suppress the target thought during a baseline period, while perceived thought control ability predicted frequency of target thoughts during suppression. Finally, results of the experimental manipulation confirmed that participants instructed to suppress experienced more intrusions during the recovery period. Clinical implications and future directions are discussed.     

Illusion of control and behavioral control attempts in obsessive-compulsive disorder

The present research used the illusion-of-control paradigm to examine the relationships among obsessive-compulsive disorder (OCD) symptoms, behavioral control attempts, and illusory sense of control. Participants were presented with a preprogrammed sequence of aversive and neutral visual stimuli and were encouraged to attempt to control the sequence with keyboard presses. Participants rated their perceived level of control 3 times during the task. In addition, the authors used the repetitiveness of keyboard presses as a measure of rigid, compulsive-like behavior. In Study 1, this procedure was administered to a sample of 55 students who also completed measures of OCD and depression. In Study 2, the task was administered to 22 participants with OCD and 22 matched participants without OCD. In line with predictions, OCD symptoms were correlated with higher illusory sense of control and with more repetitive behavioral control attempts. The authors discuss the central role of control in OCD and specifically the relationships between need for control and compulsive rituals, which may be conceptualized as means for achieving an illusory sense of control over stressful life events.     

Understanding perfectionism and depression in an adult clinical population: Is outcome expectancy relevant to psychological functioning?

Perfectionism is a personality trait defined by high standards of performance, which has been identified as a risk factor for major depressive disorder (MDD). The present study examined if outcome expectancy involved in perfectionism differs for individuals with depression compared to non-depressed controls, and how outcome expectancy relates to depression symptoms. This study included 49 depressed and 42 non-depressed participants. Perfectionism and depression severity were measured via self-report instruments. This study is the first to provide preliminary evidence that outcome expectancies involved in perfectionism may be related to psychological functioning in depression. Individuals with depression demonstrated higher negative and lower positive outcome expectancies associated with perfectionism compared to non-depressed participants. Perfectionism outcome expectancies are also related to depression severity and symptoms. Future research should prospectively investigate relationships of outcome expectancy involved in perfectionism in individuals at risk for depression.     

不同抑郁症状青少年调节不同强度情绪时策略选择的差异

最新研究发现,情绪强度会影响健康个体的情绪调节策略选择。然而,至今尚未有研究考察情绪强度对不同抑郁症状青少年策略选择的影响。对此,本研究通过流调中心用抑郁量表划分出无抑郁、阈下抑郁和抑郁症青少年,进而考察其在面对高-低强度积极-消极日常情绪事件时选择认知重评和认知沉浸的差异。结果发现：当面对高强度积极情绪、低强度积极情绪和低强度消极情绪时,三组被试的策略选择均无显著差异;当面对高强度消极情绪时,无抑郁青少年比阈下抑郁和抑郁症青少年更多选择认知重评而更少选择认知沉浸,但阈下抑郁和抑郁症青少年之间无显著差异。结果表明：不同抑郁症状青少年在面对不同强度和效价情绪时的情绪调节策略选择存在差异,表现为高强度消极情绪下抑郁症状越多的青少年越少选择认知重评而越多选择认知沉浸。这一发现有助于识别和干预青少年的抑郁症状。     

Biased attention retraining in dysphoria: a failure to replicate

The present study replicated Wells and Beevers [(2010). Biased attention and dysphoria: Manipulating selective attention reduces subsequent depressive symptoms. Cognition &; Emotion, 24, 719–728] and examined the longitudinal effects of attentional retraining on symptoms of depression. Dysphoric undergraduate psychology students were randomly assigned into either a neutral or control training condition. Training was administered using a dot-probe task that presented participants with pairs of pictures (of sad and neutral content) that were followed by a probe that participants had to respond to. Training took place over four sessions during a two-week period, followed by a final follow-up session two weeks later. Mood was measured at baseline, post-training, and at follow-up. All participants showed a significant reduction in depressive symptoms throughout the study, F(1.7, 73.55)?=?21.19, p?Cognition &; Emotion, 24, 719–728]. Implications of the findings on research on attentional retraining in the context of depression are discussed.     

The attribution of value-based attentional priority in individuals with depressive symptoms

The capture of attention by stimuli previously associated with reward has been demonstrated across a wide range of studies. Such value-based attentional priority appears to be robust, and cases where reward feedback fails to modulate subsequent attention have not been reported. However, individuals differ in their sensitivity to external rewards, and such sensitivity is abnormally blunted in depression. Here, we show that depressive symptomology is accompanied by insensitivity to value-based attentional bias. We replicate attentional capture by stimuli previously associated with reward in a control sample and show that these same reward-related stimuli do not capture attention in individuals experiencing symptoms of depression. This sharp contrast in performance indicates that value-based attentional biases depend on the normal functioning of the brain's reward system and suggests that a failure to preferentially attend to reward-related information may play a role in the experience of depression.     

Implicit memory and depression: preserved conceptual priming in subclinical depression

Depression impairs explicit memory but research on implicit memory is equivocal. Initial studies indicated preserved implicit memory, implying a depressive deficit in intentional but not unintentional forms of memory. Subsequent research indicated that conceptual priming is reduced in depression, implying a deficit in conceptual memory processes be they implicit or explicit. However, the findings with conceptual priming may be compromised by explicit contamination. The present study compared subclinically depressed and non-depressed participants on matched conceptual tests of explicit memory (category-cued recall) and implicit memory (category production). The implicit test was followed by a post-test questionnaire used to categorise participants as test-aware or test-unaware. On the explicit test, the subclinically depressed participants recalled less than the non-depressed participants. The results on the implicit test depended on test-awareness. Among test-unaware participants, conceptual priming was equivalent across the two groups, whereas for the test-aware, non-depressed participants produced significantly more priming than the subclinically depressed. This indicates that when explicit contamination is controlled, depression does not impair conceptual priming. The depressive dissociation between implicit and explicit memory is better accounted for by the difference between intentional and unintentional forms of memory rather than by the difference between conceptual and perceptual memory processes.     

Feelings of control restore distorted time perception of emotionally charged events

Humans perceive time with millisecond precision. However, when experiencing negative or fearful events, time appears to slow down and aversive events are judged to last longer than neutral or positive events of equal duration. Feelings of control have been shown to attenuate increases in arousal triggered by anxiety-provoking events. Here, we tested whether feelings of control can go as far as influencing people’s perception of the world, by modulating the perceived duration of aversive events. Observers judged the duration of images depicting positive or negative content, and we manipulated the amount of control experienced by participants. Crucially, participants never had any real control over events. All control was illusory. Results showed that when participants experienced low levels of control, negative images were judged as lasting longer than positive images. However, when participants illusorily experienced high levels of control, they no longer experienced aversive negative images as lasting longer than positive images.     

对条件化恐惧反应的抑制效应:指导性与习惯性情绪调节的作用

为了考察实验室指导性与个体习惯性情绪调控策略对恐惧反应的影响,先使用问卷调查了81名大学生的习惯性重评与抑制水平,随后将被试分为两组,指导其在条件化恐惧习得过程中进行主动的情绪调节或自然观看,24h后进行恐惧的表达测试。结果发现,习惯性抑制水平与恐惧习得及表达水平呈显著负相关,且指导性情绪调节与习惯性抑制均显著降低了恐惧习得及表达水平。这提示指导性与习惯性情绪调节策略均能够削弱应激的伤害以保护个体。