Cool and Hot Aspects of Executive Function in Childhood Obsessive-Compulsive Disorder

Aspects of executive functioning (EF) have been put forward as endophenotypes in obsessive- compulsive disorder (OCD) and meta-analyses support EF underperformance in adult samples. Childhood-onset OCD has been suggested to constitute a separate neurodevelopmental subtype of the disorder but studies on neuropsychological functioning in childhood OCD are limited. The aim of the present study was to investigate performance-based EF in pediatric OCD using observed and latent variable analyses. A case-control design was applied including 50 unmedicated children and adolescents with OCD aged 7–17 years of which 70% were female, 50 pairwise age and gender matched non-psychiatric controls (NP) and 38 children and adolescents with mixed anxiety disorders (MA). Participants underwent structured diagnostic interviews and assessment with a battery encompassing cool EF tasks of working memory, set shifting, inhibition, and planning, and hot EF tasks of decision making and dot probe paradigm affective interference. First, groups were compared on observed variables with multilevel mixed-effects linear regression and analysis of variance. Then the latent structure of cool EF was tested with confirmatory factor analysis (CFA) and groups were compared on the CFA scores. No significant differences between groups appeared on individual cool EF tasks. On the hot EF tasks the OCD group displayed significant interference effects on the dot probe paradigm OCD-specific stimuli relative to NP, but not compared to MA and no group differences emerged for decision making. In the CFA a one-factor solution showed best fit, but the groups did not differ significantly on the resulting latent variable. The present study does not support cool or hot EF impairments in childhood OCD.     

Cool and hot executive function as predictors of aggression in early childhood: Differentiating between the function and form of aggression

Executive function (EF) has been implicated in childhood aggression. Understanding of the role of EF in aggression has been hindered, however, by the lack of research taking into account the function and form of aggression and the almost exclusive focus on cool EF. This study examined the role of cool and hot EF in teacher reported aggression, differentiating between reactive and proactive as well as physical and relational aggression. Children (N = 106) completed laboratory tasks measuring cool (inhibition, planning, working memory) and hot EF (affective decision‐making, delay of gratification). Cool, but not hot, EF significantly contributed to understanding of childhood aggression. Inhibition was a central predictor of childhood aggression. Planning and working memory, in contrast, were significant independent predictors of proactive relational aggression only. Added to this, prosocial behaviour moderated the relationship between working memory and reactive relational aggression. This study therefore suggests that cool EF, particularly inhibition, is associated with childhood aggression across the different functions and forms.     

Hot and Cool Executive Function and its Relation to Theory of Mind in Children with and without Autism Spectrum Disorder

Previous research has clearly demonstrated that autism spectrum disorder (ASD) involves deficits in multiple neuropsychological functions, such as executive function (EF) and theory of mind (ToM). A conceptual distinction is commonly made between cool and hot EF. In ASD, continued attention has been paid to the cool areas of executive dysfunction. Cool EF has been strongly related to ToM, but research has not taken into account the association between hot EF and ToM in ASD. The present study investigated the associations between hot and cool EF and ToM in 56 school-aged children with ASD and 69 controls on tasks tapping cool EF (i.e., working memory, inhibition, planning), hot EF (i.e., affective decision making, delay discounting), and ToM (i.e., mental state/emotion recognition and false belief). Significant group differences in each EF measure support an executive dysfunction in both domains in ASD. Strong associations between delay discounting and ToM mental state/emotion recognition were found, suggesting that hot EF makes a unique contribution to ToM above and beyond cool EF in typical development and ASD. This study improves understanding of the profile of higher-order cognitive deficits in children with ASD, which may inform diagnosis and intervention.     

The effect of autonomous and controlled motives on eating dysregulation: Implications for individuals classified as underweight,overweight or obese

IntroductionControlled and autonomous motivational factors from self-determination theory have previously been highlighted as key factors in eating regulation. The present study examined controlled motives as an overarching motivational factor in eating dysregulation and examined its effects on dieting behaviour for those who are underweight, overweight or obese.ObjectiveTo examine whether the influence of controlled motives on dieting behaviour would be moderated by body mass index (BMI). Specifically, it was hypothesised that controlled motives would be associated with high levels of dieting behaviour in underweight individuals and low levels of dieting behaviour in individuals classified as overweight or obese.MethodOne hundred and thirty-seven participants completed the measures of height, weight, and motivation and intentions towards watching their diet and subsequently completed a measure of dieting behaviour two weeks later.ResultsModerated regression and simple slopes analyses provided support for the hypothesised effects at underweight, overweight, and obese range BMIs.ConclusionThe effect of controlled motives on dieting behaviour is dependent upon BMI and therefore varies across underweight, overweight, and obese individuals. The implications of controlled motives and external pressures to watch one's diet are discussed.     

Interrelations Between Executive Function and Symptoms of Hyperactivity/Impulsivity and Inattention in Preschoolers: A Two Year Longitudinal Study

The present study, including children at risk for developing Attention Deficit Hyperactivity Disorder (ADHD), examined the idea that complex executive functions (EFs) build upon more simple ones. This notion was applied in the study of longitudinal interrelations between core EF components — simple and complex inhibition, selective attention, and working memory (WM) — at age 5 and 6 as well as their predictive relations to ADHD symptoms at age 7. The results showed that simple inhibition and selective attention at age 5 independently predicted complex inhibition and WM at age 6. In addition, EFs primarily predicted symptoms of inattention rather than hyperactivity/impulsivity even at this young age. Finally, age 6 complex inhibition was shown to act as a mediator in the relations between simple inhibition and selective attention at age 5 and symptoms of inattention at age 7. These findings provide novel longitudinal support for the theory that fundamental EF components show a progression with age toward more complex executive control (see Garon et al. Psychological Bulletin 134(1):31–60 2008). Further, complex inhibition, implicating both inhibition and WM, seems to be a particularly strong correlate of ADHD symptoms in young children and should as such be the focus of future studies examining the relation between cognitive function and ADHD symptoms from a developmental perspective.     

Childhood Overweight and Obesity: Maternal and Family Factors

Treatment programs for childhood overweight and obesity have highlighted the importance of the family in treatment. Considering this, it is surprising that few studies have examined the role of family factors in the development of childhood overweight and obesity. The objective of this study was to examine which family and maternal factors predict increases in weight in boys and girls during middle to late childhood. This study used longitudinal data from the childhood growth and development (GAD) Study. The GAD Study involved 286 healthy weight, overweight and obese children, aged 6–13 years at baseline, who completed baseline, 1-year follow-up and 2-year follow-up assessments. Overweight/obese children were recruited from clinical and community settings. A broad range of maternal and family factors were assessed. Linear mixed models were used to identify which factors predicted child Body Mass Index (BMI) z-scores over time. For community-based children, maternal BMI and single-parent family structure were significant longitudinal predictors of child BMI z-scores. For the clinical participants, low family income was the only significant multivariate predictor of child BMI z-scores. The strong association between child BMI, maternal BMI and family structure confirms the need to target prevention and intervention efforts for childhood overweight and obesity towards families with overweight parents, particularly single-parent families.     

观点采择因素对3～4岁儿童延迟满足决策的影响

通过采用延迟满足决策任务,要求儿童分别为自己和他人做出决策,本研究考察了观点采择因素对儿童情感决策发展的影响。实验一选取3岁和4岁儿童各40名,结果发现3岁儿童和4岁儿童在为自己选和为他人选两种条件下的表现均无显著差异,都倾向于做出延迟选择。实验二选取3岁和4岁儿童各60名,在为他人的选择中进一步区分了不同的观点提示条件,并增加了观点采择测验任务。结果发现,4岁儿童的观点采择能力得到了初步的发展,在不同的观点提示条件下为他人选择时分别表现出了与为自己选择不同的决策趋势;3岁儿童尚未获得观点采择能力,在各种不同观点提示条件下为自己和为他人做选择时差异均不显著。本研究结果表明,观点采择能力对儿童情感决策的影响是发展性的。随着观点采择能力的发展,儿童逐渐能够确立正确的延迟动机,为他人做出有效的决策。     

Complementary assessments of executive function in preterm and full-term preschoolers

Executive functions (EFs) are interrelated cognitive processes that have been studied in relation to behavior, attention, academic achievement, and developmental disorders. Studies of EF skills assessed through parent report and performance-based measures show correlations between them ranging from none to modest. Few studies have examined the relationship between EF skills measured through parent report and performance-based measures in relation to adaptive function. The present study included preschool children born preterm as a population at high risk for EF impairments. Preschool children (N = 149) completed a battery of EF tasks that assess working memory, response inhibition, idea generation, and attention shifting or cognitive flexibility. Parents reported on children’s EF and adaptive skills. Preterm children showed more parent-rated and performance-based EF impairments than did full-term children. The combined use of either parent report or performance-based measures resulted in the identification of a large number of children at risk for EF impairment, especially in the preterm group. Both parent report and performance-based EF measures were associated with children’s adaptive function. EF skills are measurable in young child'ren, and we suggest that EF skills may serve as targets for intervention to improve functional outcomes. We recommend the use of both parent report and performance-based measures to characterize children’s EF profiles and to customize treatment.     

Dynamic states in working memory modulate guidance of visual attention: Evidence from an n-back paradigm

Items held in working memory (WM) can automatically bias attention when they reappear in visual displays. Recent evidence, however, suggests that WM biases of attention may be reduced under certain conditions, for example with increasing memory load. We employed a dual task paradigm to investigate how WM biases are affected by dynamic updating of memory contents. 1-back and 2-back versions of a memory task with colour stimuli were interrupted at intervals by an unrelated visual search task. Reappearance in the search display of the item that was currently active in WM guided attention, while suppressed or inactive items did not. We conclude that the rapid updating of memory contents facilitates the shifting of memory representations into different activity states on a moment-to-moment basis. The finding is consistent with models that propose that only one item can be “active” in WM at any one time to guide attention.     

Problematic eating behaviors and nutritional status in 7 to 12 year-old Chilean children

Overweight and obesity are medical conditions that require a multidisciplinary analysis of their causes and treatment. In Chile a sustained increase in the presence of obesity and excess weight has been observed in children. However, the amount and the dynamics of the aforementioned problematic eating behaviours in Chilean children are unknown. The aim of this study was to assess the relationship between restrained, external, and emotional eating, and variations in body mass index (BMI) in Chilean children. Consequently, 453 children from 7 to 12 years of age responded to the Children's Dutch Eating Behaviour Questionnaire, Spanish version. In addition, their anthropometric data were obtained. A positive association was found between restrained eating and BMI, and a negative correlation between external eating and BMI. Emotional eating demonstrated a modest inverse relationship with BMI. A significant interaction between problematic behaviour and nutritional status (normal-weight, overweight, obese) was revealed. Restrained eating was characteristic of obese children whereas external eating of normal-weight children. These results suggest that problematic eating behaviours and their relationship with body weight are similar to those described in studies in Europe.     

Hot and cool executive function in children and adolescents with autism spectrum disorder: Cross-sectional developmental trajectories

The development of executive function (EF) in autism spectrum disorder (ASD) has only been investigated using “cool”-cognitive-EF tasks. Little is known about the development of “hot”-affective-EF and whether it follows a similar developmental pathway. This study employed a cross-sectional developmental trajectories approach to examine the developmental changes in cool (working memory, inhibition, and planning) and hot EF (delay discounting and affective decision-making) of ASD participants (n = 79) and controls (n = 91) relative to age and IQ, shedding more light on the hot–cool EF organization. The developmental trajectories of some aspects of cool EF (working memory and planning) differed significantly as a function of age in ASD participants relative to controls. For both hot EFs, no significant age-related changes were found in either group. These findings extend our understanding regarding the maturation of EF from childhood through adolescence in ASD.     

Association Between Body Mass Index and Motor Competence in Santal Children of Purulia District,India

The purpose of this study was to evaluate the relationship between body mass index and motor competence in Santal children 5–12 years old. A total of 816 Santal children were studied. Children's adiposity status was assessed by body mass index (BMI) for age z-score based on World Health Organization reference data. Motor competence was measured using the Bruininks-Oseretsky Test of Motor Competence (BOT-2). There was no significant difference in mean BMI z-score between Santal boys (0.13 ± 0.07) and girls (?0.14 ± 0.07). Healthy weight (HW) children scored higher (p < .05) in some individual motor subtests (bilateral competence, balance, running speed and agility, upper limb competence, and strength) and in total BOT-2 score (p < .05) compared with scores for underweight (UW) and overweight (OW) children. Nonlinear regression analysis showed that BMI is a significant independent predictor of motor competence (p < .01). Motor competence showed a curvilinear relationship with BMI-z-score, with the lowest point motor scores in strength and upper limb competence (p < .05) for both UW and OW children compared to HW children who scored highest. The results also indicated that gross motor skills, but not fine motor skills, were poorer among children who were UW or OW compared with HW children.     

Developmental trajectories in toddlers' self-restraint predict individual differences in executive functions 14 years later: a behavioral genetic analysis

We examined whether self-restraint in early childhood predicted individual differences in 3 executive functions (EFs; inhibiting prepotent responses, updating working memory, and shifting task sets) in late adolescence in a sample of approximately 950 twins. At ages 14, 20, 24, and 36 months, the children were shown an attractive toy and told not to touch it for 30 s. Latency to touch the toy increased with age, and latent class growth modeling distinguished 2 groups of children that differed in their latencies to touch the toy at all 4 time points. Using confirmatory factor analysis, we decomposed the 3 EFs (measured with latent variables at age 17 years) into a Common EF factor (isomorphic to response inhibition ability) and 2 factors specific to updating and shifting. Less-restrained children had significantly lower scores on the Common EF factor, equivalent scores on the Updating-Specific factor, and higher scores on the Shifting-Specific factor than did the more-restrained children. The less-restrained group also had lower IQ scores, but this effect was entirely mediated by the EF components. Twin models indicated that the associations were primarily genetic in origin for the Common EF variable but split between genetics and nonshared environment for the Shifting-Specific variable. These results suggest a biological relation between individual differences in self-restraint and EFs, one that begins early in life and persists into late adolescence.     

Mental Set Shifting in Childhood: The Role of Working Memory and Inhibitory Control

The role of working memory (WM) and inhibition in mental set shifting was examined from an individual difference perspective in children aged 5–14 years (N = 117). Using the Hearts and Flowers task the rationale of the present study was to directly test the theoretical assumption that mental set shifiting in childhood primarily builds on WM and inhibitory processes. Theoretical predictions about WM and inhibitory demands in the congruent and incongruent conditions of the Hearts and Flowers task were also considered because these blocks underlie relevant measures of set shifting. The findings show that both WM and inhibition (extracted as factors in confirmatory factor analysis) are important for set shifting but that this general association is driven by the link between these executive functions (EFs) and the goal‐representation aspect (i.e. global switch costs) of shifting, rather than to the actual switch‐implementation process (i.e. local switch costs). In addition, our findings are novel in showing that, despite a substantial correlation between the two EF components, it was the variance specific to WM and inhibition that was important for mental set shifting. Copyright © 2014 John Wiley & Sons, Ltd.     

Somatic markers,working memory,and decision making

The somatic marker hypothesis formulated by Damasio (e.g., 1994; Damasio, Tranel, & Damasio, 1991) argues that affective reactions ordinarily guide and simplify decision making. Although originally intended to explain decision-making deficits in people with specific frontal lobe damage, the hypothesis also applies to decision-making problems in populations without brain injury. Subsequently, the gambling task was developed by Bechara (Bechara, Damasio, Damasio, & Anderson, 1994) as a diagnostic test of decision-making deficit in neurological populations. More recently, the gambling task has been used to explore implications of the somatic marker hypothesis, as well as to study suboptimal decision making in a variety of domains. We examined relations among gambling task decision making, working memory (WM) load, and somatic markers in a modified version of the gambling task. Increased WM load produced by secondary tasks led to poorer gambling performance. Declines in gambling performance were associated with the absence of the affective reactions that anticipate choice outcomes and guide future decision making. Our experiments provide evidence that WM processes contribute to the development of somatic markers. If WM functioning is taxed, somatic markers may not develop, and decision making may thereby suffer.     

Executive Functions in Preschool Children with Aggressive Behavior: Impairments in Inhibitory Control

The question whether executive function (EF) deficits in children are associated with conduct problems remains controversial. Although the origins of aggressive behavior are to be found in early childhood, findings from EF studies in preschool children with aggressive behavior are inconsistent. The current study aimed to investigate whether preschool children with aggressive behavior show impairments in EF. From a population-based sample, 82 preschool children who were showing aggressive behavior as indicated by scores at or above the 93rd percentile on the Aggressive Behavior Scale of the CBCL 1 1/2-5 were selected. These children with aggressive behavior were matched on IQ to a group of typically developing control children (N = 99). Six neuropsychological tasks were administered to assess set shifting, inhibition, working memory and verbal fluency. A factor analysis was conducted which yielded one clear factor: inhibition. Aggressive preschool children showed poorer performance on this inhibition factor than control children and boys performed worse on this factor than girls. This association between aggressive behavior and inhibition deficits was maintained after controlling for attention problems. In addition, gender differences in all EFs measured were found with boys exhibiting more impairment in EF than girls. These findings demonstrate that preschool children with aggressive behavior show impairments in inhibition, irrespective of attention problems.     

中国儿童青少年跨期决策的发展与脑发育机制

跨期决策是指人们对时间成本与收益进行权衡, 进而做出评价与选择, 其研究主要围绕时间折扣, 是指与当前或近期的损益相比, 人们赋予未来损益更小的权重。虽然有争议, 但Mischel等人很早就通过著名的“棉花糖实验”证明了延迟满足能力越强的儿童有着更高的学业成就。延迟满足与跨期决策都是在时间维度上进行的决策。研究者通过脑成像技术发现了成人大脑内支持跨期决策的三个神经网络系统, 但关于儿童的研究鲜有报道。这三大脑网络系统都位于额叶皮层, 该皮层在儿童青少年时期快速发育。通过采用横断研究和纵向研究相结合的实验设计, 对处于跨期决策发展关键期的中国儿童青少年人群进行测查和追踪; 借助神经影像技术, 考察跨期决策发展与脑发育的关系; 整合多模态神经影像技术, 构建可以预测跨期决策能力的脑影像指标。     

母亲敏感性与婴儿气质、注意对学步儿执行功能影响的交互作用：一项两年的追踪研究

为同时探究外部因素与内部因素对学步儿执行功能的影响, 对163对母婴进行追踪测量。婴儿6个月时根据母婴自由互动录像编码母亲敏感性; 使用最长注视时长范式测量婴儿注意特征; 使用母亲报告的《婴儿行为问卷—修订短版》测量婴儿气质; 24个月时使用多位置寻找任务、形状Stroop任务、逆转分类任务、延迟满足任务测量学步儿执行功能。结果发现：(1)婴儿6个月最长注视时长能够显著正向预测24个月的多位置寻找与延迟满足任务得分。(2)母亲敏感性能够正向预测气质外向性低的婴儿24个月时的逆转分类任务表现, 对气质外向性高的婴儿24个月时的逆转分类任务表现的预测不显著。(3)母亲敏感性能够正向预测最长注视时长更长的婴儿24个月时的形状Stroop任务得分; 负向预测最长注视时长更短的婴儿24个月时的形状Stroop任务得分。研究发现了针对不同特征的婴儿, 母亲的养育敏感性对学步儿执行功能影响的差异, 这对早期教育应该如何“因材施教”有所启示。     

Are sluggish cognitive tempo symptoms associated with executive functioning in preschoolers?

The aim of this study is to investigate whether sluggish cognitive tempo (SCT) symptoms are associated with neurocognitive task performance and ratings of real-world executive functioning (EF) in preschoolers at risk for attention-deficit/hyperactivity disorder (ADHD). The associations between parent- and teacher-rated SCT symptoms and neuropsychological task performance and ratings of EF in 61 4-year-old preschool children (51 boys, 10 girls) with self-regulation difficulties were examined, with regression analyses controlling for the effects of ADHD inattention symptoms. In the study sample, higher teacher-rated SCT symptoms are significantly associated with poorer performance on tasks of visual-perceptual abilities, auditory and visual attention, sustained and selective attention, inhibitory control, pre-numerical/numerical concepts, and slower processing speed, but SCT symptoms are not significantly associated with working memory, attention shifting or cognitive flexibility when controlling for ADHD inattention. Higher parent-rated SCT symptoms are significantly associated with visual-perceptual abilities. ADHD inattention symptoms are more strongly associated than SCT with daily life EF ratings; neither parent- nor teacher-rated SCT symptoms are significantly associated with daily life ratings of inhibition, working memory, or planning/organization after controlling for ADHD inattention. This study suggests that SCT symptoms contribute to EF deficits at least on neurocognitive tasks assessing visual-perceptual/spatial abilities, attention to detail and processing speed, as observed in this sample of young children at risk for ADHD, and may be an important intervention target.     

Gender differences in the accuracy of self-reported weight

To investigate gender as a possible moderator of the validity of self-reported weight data in studies of body image and eating disorders, the discrepancies between reported weights and actual weights were examined in a sample of 186 college students, 90 males and 96 females. Ninety-four percent of the students were Anglo-American, and 6% were African-American, Asian-American, or Hispanic. In comparison to male students, female students underreported their weight to a significantly greater degree. Generally, use of self-reported weight, rather than actual weight, would result in more subjects classified as normal weight or underweight and fewer classified as overweight, using standard methods of classifying individuals into weight categories. And consistent with previous research, normal-weight females perceived themselves as overweight while normal-weight males were more likely to perceive themselves as underweight. Implications for further research on gender differences in eating problems and body image are discussed.To whom reprint requests should be addressed at Department of Psychology, 210 McAlester Hall, University of Missouri, Columbia, MO 65211.