"Frog, where are you?" Narratives in children with specific language impairment, early focal brain injury, and Williams syndrome

In this cross-population study, we use narratives as a context to investigate language development in children from 4 to 12 years of age from three experimental groups: children with early unilateral focal brain damage (FL; N=52); children with specific language impairment (SLI; N=44); children with Williams syndrome (WMS; N=36), and typically developing controls. We compare the developmental trajectories of these groups in the following domains: morphological errors, use of complex syntax, complexity of narrative structure, and types and frequency of evaluative devices. For the children with early unilateral brain damage, there is initial delay. However, by age 10, they are generally within the normal range of performance for all narrative measures. Interestingly, there are few, if any, side specific differences. Children with SLI, who have no frank neurological damage and show no cognitive impairment demonstrate significantly more delay on all morphosyntactic measures than the FL group. Quantitatively, on morphosyntactic measures, the SLI group clusters with those children with WMS who are moderately retarded. Together these data help us to understand the extent and nature of brain plasticity for language development and those aspects of language and discourse that are dissociable.     

The Relation between Motivation and Goal Attainment: A Correlational Meta-Analysis

This meta-analysis investigated the strengths of the relationship between various types of motivations and accompanying future outcomes that individuals intend to change, based upon 337 effect sizes from 62 studies. Considerable variation exists within and between the effect sizes of the 14 types of motivations, ranging from a small negative effect size, r = −.13, I² = 93.85% (k = 13), to a medium positive effect size, r = .38, I² = 0.0% (k = 3). The following factors moderated some of the 14 summary effect sizes: (a) the type of assessment data (self-report vs. physical data); (b) the type of future outcomes (physical behavior, psychological state, and intellectual ability); (c) the use of a motivational intervention; (d) the use of a longitudinal design; and (e) the time period between the point that measured motivation and future outcomes. The moderating effects suggest that the effect size of motivations may fluctuate across various domains, while future outcomes may be almost unaffected or even affected negatively by particular types of motivations, although certain other types of motivations play positive roles.     

Intelligence and regional brain volumes in normal controls

The relationship between brain size and intelligence was examined in a large sample of healthy normal volunteers (N = 90). In addition to confirmation of the small but significant relationship between IQ and whole brain volume (r = 0.25, p < .05) using magnetic resonance imaging, regional differences were examined using a completely automated procedure to generate lobar volumes to address questions related to regional specificity and its relationship to intelligence. A significant positive relationship was found between measures of full scale IQ and frontal (r = 0.25, p < .05) and temporal (r = 0.28, p < .01) regions, although when correlations across different brain regions were tested against each other, there was no evidence of regional specificity. In addition, no laterality effects were seen. Correlations between WAIS-R subtest scores and brain regions indicated few correlations between verbal subtest scores and brain size, but several significant correlations between the performance subtest scores and frontal, temporal, parietal, and cerebellar brain regions. These results support the notion of a modest relationship between brain size and measures of global intelligence and suggest diffuse brain involvement on performance tasks which require integration and use of multiple cognitive domains.     

Anterior cingulate cortex findings in child disruptive behavior disorders.: A meta-analysis

The brain imaging literature suggests that child disruptive behavior disorders (DBD) are associated with structural and functional abnormalities of the anterior cingulate cortex (ACC).However, there is a lot of heterogeneity in findings in terms of direction of modifications identified until this point. The present study used a meta-analytic design to aggregate the empirical findings from the literature on functional and structural abnormalities of the ACC in children with DBD. A total of eight structural and functional brain imaging (sMRI and fMRI) studies were included and results obtained from a sample of 266 children show a large effect size (D = ?.98 (95% CI [? 1.18, ? 0.77]) in terms of reduced activation of the ACC in children presenting with DBD. Effects of ACC abnormality were moderated by: 1) the type of imaging used in the study (i.e., functional vs. structural); 2) the presence or absence of co-morbid attention deficit hyperactivity disorder (ADHD); 3) the mean age of the samples of children presenting with DBD. Overall, findings confirm functional impairments of the ACC in children with DBD and highlight the importance of using such neurological information to design innovative treatments.     

Cognitive effects of hormone therapy in early postmenopausal women

Recent reports suggest that hormone therapy (HT) with estrogen may have a protective effect on the ageing brain and cognitive function. However, clinical evidence regarding the cognitive effects in menopausal women under HT has produced conflicting results. The purpose of the present study was to assess and compare the cognitive effects after 6 months of HT in 30 early postmenopausal women, who were divided into three groups as follows: group I, Therapy conjugated equine estrogen (ET) CEE 0.625 mg/day (n = 10); group II, Estrogen‐Progestin Therapy (EPT), CEE 0.625 mg/day plus, chlormadinone 1 mg/day (n = 10); and group III, the control group, who did not receive treatment (n = 10). The three groups were matched by age and years of education. Exclusion criteria were: central nervous system diseases, severe cardiac disease, and clinical history of cancer and depression. Subjects were tested using a comprehensive battery for the evaluation of attention, memory and executive functions, which was standardized and validated in Spanish‐speaking subjects. The rate of cognitive change was defined by the difference between the measurements at the sixth month minus the baseline score. Mean group differences were assessed with MANOVA, followed by one‐way ANOVA considering statistical significance when p < .05; the alpha significance level .05 was corrected using the Bonferroni procedure. The EPT group showed higher scores than the control group and ET group in the Total Attention Score and in the copy of the Rey‐Osterreith Complex Figure. The ET group showed significantly higher scores than the control group and the EPT group in the subtest of Spatial Backward Span and in the Immediate Face Codification. The short‐term positive effects observed with HT in this sample could be related to the stimulation of brain receptors and/or neurotrophic factors that are still present at this age.     

The long‐term effects of institutional rearing,foster care intervention and disruptions in care on brain electrical activity in adolescence

Exposure to early psychosocial deprivation as a result of institutional care disrupts typical brain development. The Bucharest Early Intervention Project (BEIP) is the first longitudinal study to investigate the neurodevelopment of institutionalized infants randomized to a foster care (FCG) intervention versus care as usual (CAUG). Here, we present findings from a follow‐up assessment of brain electrical activity as indexed by resting EEG at age 16 years. In addition, we examined the effects of disruption of foster care placement (e.g. the number of moves among foster care placements) on brain electrical activity. Resting‐state EEG was collected from 48 CAUG, 46 FCG and 48 never institutionalized (NIG) control participants. Absolute (µV²) and relative (proportion) power were computed from eyes closed, resting EEG data for theta, alpha and beta frequency bands. The CAUG displayed higher relative theta and lower relative alpha power compared to the FCG at 16 years of age. The FCG showed brain activity comparable to the NIG. The results further showed that disruptions following the original foster care placement had an adverse effect on brain electrical activity. Within the foster care group, there were no effects of age of placement on EEG power. Placement of children who have experienced early institutional rearing into stable foster care settings ensure long‐term improvement in brain functioning.     

Structural brain abnormalities in the major psychoses: a quantitative review of the evidence from computerized imaging

The neuroimaging literature on structural brain abnormalities in the major psychoses is quantitatively reviewed. The mean effect size for studies of lateral ventriculomegaly in schizophrenia (d = .70) corresponded to 43% nonoverlap between the distributions of schizophrenics and control Ss. Planimetry yielded larger effects than linear methods of ventricular size estimation. Although enlargement of the third ventricle was comparable to that of lateral ventriculomegaly (d = .66), it was found to be significantly greater after differences in measurement method were taken into account. The average cumulative length of hospitalization, adjusted for patients' age and duration of illness, predicted ventriculomegaly in schizophrenia. Studies on schizophrenia and affective disorder differed neither in the extent of reported ventriculomegaly nor in the amount of "cortical atrophy."     

Developmental associations between externalizing behaviors, peer delinquency, drug use, perceived neighborhood crime, and violent behavior in urban communities

This study examines the precursors of violent behavior among urban, racial/ethnic minority adults. Data are from an on-going study of male and female African Americans and Puerto Ricans, interviewed at four time waves, Time 1-Time 4 (T1-T4), from adolescence to adulthood. Structural Equation Modeling was used to analyze the developmental pathways, beginning in mid-adolescence (T1; age = 14.0 years), to violent behavior in adulthood (T4; age = 29.2 years). The variables assessed were: components of externalizing behaviors (i.e., rebelliousness, delinquency; T1, T3); illicit drug use (T2); peer delinquency (T2); perceived neighborhood crime (T4); and violent behavior (T3, T4). Results showed that the participants' externalizing behaviors (rebelliousness and delinquency) were relatively stable from mid-adolescence (T1; age = 14.0 years) to early adulthood (T3; age = 24.4 years). The participants' externalizing behaviors in mid-adolescence also had a direct pathway to peer delinquency in late adolescence (T2; age = 19.1 years). Peer delinquency, in turn, had a direct pathway to the participants' illicit drug use in late adolescence (T2), and to externalizing behaviors in early adulthood (T3). The participants' illicit drug use (T2; age = 19.1 years) had both direct and indirect paths to violent behavior in adulthood (T4). The participants' externalizing behaviors in early adulthood (T3) were linked with violent behavior at T3, and perceived neighborhood crime (T4), both of which had direct pathways to violent behavior in adulthood (T4). The findings suggest developmental periods during which externalizing behaviors, exposure to delinquent peers, illegal drug use, and neighborhood crime could be targeted by prevention and intervention programs in order to reduce violent behavior.     

Children's academic attainment is linked to the global organization of the white matter connectome

Literacy and numeracy are important skills that are typically learned during childhood, a time that coincides with considerable shifts in large‐scale brain organization. However, most studies emphasize focal brain contributions to literacy and numeracy development by employing case‐control designs and voxel‐by‐voxel statistical comparisons. This approach has been valuable, but may underestimate the contribution of overall brain network organization. The current study includes children (N = 133 children; 86 male; mean age = 9.42, SD = 1.715; age range = 5.92–13.75y) with a broad range of abilities, and uses whole‐brain structural connectomics based on diffusion‐weighted MRI data. The results indicate that academic attainment is associated with differences in structural brain organization, something not seen when focusing on the integrity of specific regions. Furthermore, simulated disruption of highly‐connected brain regions known as hubs suggests that the role of these regions for maintaining the architecture of the network may be more important than specific aspects of processing. Our findings indicate that distributed brain systems contribute to the etiology of difficulties with academic learning, which cannot be captured using a more traditional voxel‐wise statistical approach.     

Relationships between factors of intelligence and brain volume

The recent explosion of studies aimed at determining the biological basis of intelligence has revealed that cognitive ability has a strong biological substrate. This study expands on this literature by examining the relation between cognitive ability and MRI-measured brain volume and head size in a sample of adult male siblings recruited from the London, Ontario community in Canada. It was found that brain volume correlated with IQ at 0.35 (P<0.01), thus replicating the results of past studies. Corrections for restriction of range and attenuation in both this and past studies suggest that the population value of the brain volume-IQ correlation is closer to 0.50. Head size variables, with one exception, also showed the expected positive correlations with IQ. The results of a vector analysis on factor scores indicated that the more highly g-loaded a test was the more highly it correlated with brain volume (r=0.59, P<0.01). The sum of the data suggested that although brain volume (and to a lesser extent, head size) is predictive of g, fluid ability, and memory, it does not predict crystallized ability. Unexpectedly, the higher the spatial imaging loading of a test, the less its correlation with brain volume (vector correlation=−0.84, P<0.001).     

Brain size and cognitive ability: Correlations with age,sex, social class,and race

Using data from magnetic resonance imaging (MRI), autopsy, endocranial measurements, and other techniques, we show that (1) brain size is correlated with cognitive ability about .44 using MRI; (2) brain size varies by age, sex, social class, and race; and (3) cognitive ability varies by age, sex, social class, and race. Brain size and cognitive ability show a curvilinear relation with age, increasing to young adulthood and then decreasing; increasing from women to men; increasing with socioeconomic status; and increasing from Africans to Europeans to Asians. Although only further research can determine if such correlations represent cause and effect, it is clear that the direction of the brain-size/cognitive-ability relationships described by Paul Broca (1824–1880), Francis Galton (1822–1911), and other nineteenth-century visionaries is true, and that the null hypothesis of no relation, strongly advocated over the last half century, is false.     

Does parochial cooperation exist in childhood and adolescence? A meta-analysis

Although previous meta-analytic evidence supports the existence of parochialism in cooperation among adults, the extent to which children and adolescents are more willing to incur a personal cost to benefit ingroups, compared to outgroups, is not yet clear. We provide the first meta-analysis on the existence and magnitude of parochialism in cooperation among pre-adults. Based on 20 experimental economics studies (k = 69, N = 5268, age = 3–19, 12 countries, published 2008–2019), a multilevel meta-analytic model revealed a small overall effect size indicating that children and adolescents were more cooperative towards ingroups (d = 0.22, 95% CI [0.07, 0.38]). A series of single-moderator analyses tested for the following conditions: participant age and sex; game type ([mini-]dictator game, prisoner's dilemma, public goods dilemma, trust game, ultimatum game); outcome interdependence; membership manipulation (between- vs. within-subjects); group type (natural vs. experimental); reward type (monetary vs. non-monetary); and country of the participant. Parochial cooperation did not vary with participants' age. Parochialism was larger in non-interdependent (dictator-type) compared to interdependent (bargaining and social dilemma) games. There were no moderating effects of group type, membership manipulation or reward type. To provide more data on how parochialism develops, primary studies should report age ranges more precisely and use more restricted age groups.     

Relations between a laboratory-based sustained attention task and traffic violations in an Iranian sample of drivers

The role of cognitive abilities regarding driver behavior is crucially important in the occurrence of traffic violations and preventing tragic motor vehicle collisions. Sustained attention is one cognitive ability that may contribute to safe driving behavior. The present study investigated the relation between sustained attention and traffic violations. One hundred and one Iranian male drivers (age: M = 37.17, SD = 8.37) with at least 2 years driving experience voluntarily participated in the study. Participants were categorized into two groups based on the number of driving rule violations they committed over the last 2 years (n = 48 clean record, n = 53 violators). Sustained attention was measured by performance on the Conjunctive Continuous Performance Task (CCPT). Four CCPT performance measures were computed: (1) Mean reaction time for correct responses (M-RT); (2) standard deviation of reaction times for correct responses (SD-RT); (3) percent of omission errors (failure to respond to target stimulus); (4) percent of commission errors (identification of a non-target stimulus as target). Results showed after controlling for age and education, there was a significant group difference on M-RT, indicating that individuals with no traffic violations had faster reaction times as compared to those who had 1 or more traffic violations. No effect of group on any of the other outcomes was present after correcting for alpha inflation. When assessing the effect of age and education, education was significantly related to average reaction time and percent of omission errors. No significant effect of age was apparent. Findings suggest cognitive function, specifically sustained attention measured with a laboratory-based measure, may be associated with safe driving behavior.     

Cross-cultural effects of parent warmth and control on aggression and rule-breaking from ages 8 to 13

We investigated whether bidirectional associations between parental warmth and behavioral control and child aggression and rule-breaking behavior emerged in 12 cultural groups. Study participants included 1,298 children (M = 8.29 years, standard deviation [SD] = 0.66, 51% girls) from Shanghai, China (n = 121); Medellín, Colombia (n = 108); Naples (n = 100) and Rome (n = 103), Italy; Zarqa, Jordan (n = 114); Kisumu, Kenya (n = 100); Manila, Philippines (n = 120); Trollhättan/Vänersborg, Sweden (n = 101); Chiang Mai, Thailand (n = 120); and Durham, NC, United States (n = 111 White, n = 103 Black, n = 97 Latino) followed over 5 years (i.e., ages 8–13). Warmth and control were measured using the Parental Acceptance-Rejection/Control Questionnaire, child aggression and rule-breaking were measured using the Achenbach System of Empirically-Based Assessment. Multiple-group structural equation modeling was conducted. Associations between parent warmth and subsequent rule-breaking behavior were found to be more common across ontogeny and demonstrate greater variability across different cultures than associations between warmth and subsequent aggressive behavior. In contrast, the evocative effects of child aggressive behavior on subsequent parent warmth and behavioral control were more common, especially before age 10, than those of rule-breaking behavior. Considering the type of externalizing behavior, developmental time point, and cultural context is essential to understanding how parenting and child behavior reciprocally affect one another.     

Erotophobia and contraception among Zimbabwean students

Unplanned pregnancies are of great concern to the government of Zimbabwe. In Zimbabwe, at least 1/3rd of the women (15-19 years) had been pregnant at least once; and only 27% of married Zimbabwe women use some form of contraception. Various North American researchers believe that erotophobia (negative feelings about sex) is in some way responsible for increase sexual relations and lack of concern over contraception. A study was conducted on 178 Zimbabwean students (104 males, 74 females), with a mean age of 22.03 to discover attitudes about sex. The alpha coefficient reliability of the Sexual Opinion Survey was .40. The results of the findings are as follows: extremely religious (r = .18, p .05); frequency of reading erotica; (r = .41, p .01); occurrence of sexual dreams (r = .39, p .01); and disapproval of premarital sex (r = .38, p .02). Signs of erotophobia could also be found in reporting the chance of sex in the future (r = -.41, p .01); the belief that contraception leads to sexual promiscuity (r = -.17, p .05); the belief that the use of contraception leads to feelings of guilt (r = -13, p .05); reported likelihood of engaging in public actions to obtain contraceptives (r = .29, p .01); and the reported continued use of contraception (r = .14, p .05). The reliability of the Sexual Opinion Survey was moderate; however, it would be best if a survey, taking into account the Zimbabwean culture and attitudes towards sex, is developed.     

社会支持与成年早期孤独感：有调节的中介模型

为探讨社会支持与成年早期孤独的关系,调查了556名大学生,运用SEM法、Bootstrap法、多组分析法考察社交自我效能与负性情绪在其中的影响机制及留守经历的调节。结果表明：社交自我效能、负性情绪在社会支持和孤独感之间的中介效应显著;社交自我效能和负性情绪在社会支持对孤独感的影响中起链式中介作用;留守经历对社会支持和孤独感关系存在调节作用。研究结果证实了社会支持影响孤独感及社交自我效能和负性情绪在其中的内在机制。     

Preferences for ‘Gender‐typed’ Toys in Boys and Girls Aged 9 to 32 Months

Many studies have found that a majority of boys and girls prefer to play with toys that are typed to their own gender but there is still uncertainty about the age at which such sex differences first appear, and under what conditions. Applying a standardized research protocol and using a selection of gender‐typed toys, we observed the toy preferences of boys and girls engaged in independent play in UK nurseries, without the presence of a parent. The 101 boys and girls fell into three age groups: 9 to 17 months, when infants can first demonstrate toy preferences in independent play (N = 40); 18 to 23 months, when critical advances in gender knowledge occur (N = 29); and 24 to 32 months, when knowledge becomes further established (N = 32). Stereotypical toy preferences were found for boys and girls in each of the age groups, demonstrating that sex differences in toy preference appear early in development. Both boys and girls showed a trend for an increasing preference with age for toys stereotyped for boys. Theoretical implications of the findings are discussed with regard to biological predispositions, cognitive development and environmental influences on toy preference. Copyright © 2016 John Wiley & Sons, Ltd.     

Betrayed? That’s Me: Implicit and Explicit Betrayed Self-Concept in Young Adults Abused as Children

Attenuated awareness of betrayal, or “betrayal blindness,” is a proposed survival mechanism in relationships where awareness of betrayal will mobilize confront-or-withdraw responses that jeopardize a needed relationship. Empirical tests of betrayal blindness and its effects are hampered by the methodological conundrum of how to measure an absence of awareness. The purpose of this study was to evaluate the validity of a novel empirical method to measure implicit betrayed self-concept, the first step in a long-term research aim to operationalize “betrayal blindness.” Informed by betrayal trauma theory, we hypothesized that a history of betrayal within close childhood relationships (but not recent close relationships or “not-close” relationships) would predict implicit betrayed-self associations in young adulthood. An adaptation of the Implicit Association Test (IAT) and measured implicit and explicit betrayed-self associations and self-reported history of physical, sexual, and psychological abuse in 529 university undergraduates was designed. Internal consistency reliability of the betrayed self IAT was low but adequate. Hierarchical regression modeling revealed that history of abuse within close childhood relationships (but not recent close relationships or “not-close” relationships) predicted betrayed-self IAT scores. The effect size was small, β = .12, p < .05, 95% CI [.01, .07], R² = .12. In addition, history of betrayal by someone close (but not someone “not close”) at any age predicted increased explicit evaluations of the self as betrayed versus respected, a small effect size, R² = .16. Findings indicate that implicit betrayed self-concept can be measured empirically.     

Sex differences in human brain size and the general meaning of differences in brain size.

Contrary to commonly held convictions, there is no clear association between brain size and body parameters in humans. Within sexes, once age and health status are controlled for, there is no significant association between brain size and body height for females. For males, body height accounts for no more than .04% of the variance in brain size. The relation between brain weight and body weight is even less clearly defined. Nevertheless, there are large and significant differences in brain size between the sexes. If no adequate body parameters can be found that scale to brain size within the sexes, the marked dimorphism between males and females makes it even more difficult to find a common set of parameters that allow evaluation of brain size differences between sexes. Within and across sexes, there is no convincing link between a limited measure of behavioural capacity (IQ) and brain size. This leads to the more general question: Why would one expect such a link, and, if it is not found, what does this mean in the context of general theories of cortical function?