The effects of muscle relaxation on blood pressure of essential hypertensives

Muscle relaxation and noncontinuous biofeedback were investigated as potential nonpharmaceutical treatments for essential hypertension. The two procedures were compared to a waiting list control group. Predictions were made regarding the overall treatment effect, sessions within treatment effect, and periods within session effect. The results of this experiment reveal that biofeedback significantly lowers diastolic blood pressure between premeasures and postmeasures. It was also shown that muscle relaxation has a significant effect upon lowering diastolic and systolic blood pressures between premeasures and postmeasures and has a significant effect upon lowering diastolic and systolic blood pressures as subjects progress from the first period of a treatment session to the last period of a treatment session.     

Chronic painless recording of intra-arterial blood pressure in unanesthetized dogs

A method for measuring intra-arterial blood pressure in unanesthetized dogs for as long as 12 months through the implantation of polyvinyl catheters in the abdominal aorta is described. Direct intra-aortic pressures ranged from 135 to 204 mm Hg for systolic blood pressures and 57 to 123 mm Hg for diastolic blood pressures over periods ranging from 8 to 12 months. This method provides a means for following blood pressure for a long period with minimal disturbance in the behavior of the animal. This also makes possible an additional cardiovascular measurement in the studies of the cardiac conditional reflexes.     

Voluntary Blood Pressure Control: Operant Conditioning by a Continuous Blood Pressure Feedback Technique

Abstract

The present study evaluated a single session operant conditioning of blood pressure in borderline hypertensives. A double blind randomized two period (each lasting for 20 minutes) cross over study consisting of a treatment (operant conditioning of mean arterial blood pressure) and a control condition (heart rate) was performed. Sequence of treatments was randomly assigned. Fourteen borderline hypertensive subjects participated and were trained to decrease their continuously measured blood pressure (Finapres) and heart rate. Subjects receiving blood pressure feedback during the first session showed a significant (4.3 mmHg) decrease in diastolic blood pressure. In contrast, subjects receiving blood pressure training during the second session showed a non-significant increase in diastolic blood pressure. Treatment consisting of more sessions is a promising adjunct to antihypertensive regimens.     

Anxiety management training in the treatment of essential hypertension

The study was conducted to assess the efficacy of Anxiety Management Training as an adjunctive treatment for essential hypertension. Twenty-one patients with essential hypertension, all but one of whom were on antihypertension medication, were randomly assigned either to an Anxiety Management Training condition or a waiting-list control condition. At the time of a posttest assessment session, compared to subjects in the control condition, subjects in the Anxiety Management Training condition manifested a decrease in resting systolic and diastolic blood pressure and a decrease in systolic and diastolic blood pressure following a stressful task. At the time of a follow-up assessment session, subjects in the Anxiety Management Training condition not only manifested good maintenance of reduced blood pressure but also exhibited a further decrease in resting systolic blood pressure and a decrease in systolic blood pressure during the stressful task.     

The effects of short term flotation REST on relaxation: a controlled study

The purpose of this study was to compare the effects of restricted environmental stimulation using a flotation tank (Flotation REST) to the effects of a normal sensory environment on relaxation. All of the subjects were first introduced to a simple relaxation program to be used during the experimental sessions. The program consisted of guided point-to-point relaxation, breathing techniques, and visual imagery techniques. Subjects were then pre-tested on measurements of electromyogram (EMG), galvanic skin response (GSR), peripheral skin temperature, and systolic and diastolic blood pressure. The experimental group experienced ten 45-minute sessions practicing the relaxation program in a Flotation REST environment. The control subjects practiced the same relaxation program in a similar body position for 45 minutes in a normal sensory environment. All subjects answered a five-question Subjective Relaxation Questionnaire on trials five through ten and were then post-tested on EMG, GSR, skin temperature, and blood pressure. The results indicated significant differences between groups from pre-test to post-test on systolic and diastolic blood pressure; the experimental group showed greater reductions. Significant differences also were observed on three of five questions on the Subjective Relaxation Questionnaire; the experimental group reported greater subjective relaxation and trends in a similar direction on the remaining two questions. The results of this study indicate that flotation REST enhances point-to-point relaxation, breathing techniques, and visual imagery techniques and, when combined with these techniques, can be an effective means of teaching normal subjects to lower systolic and diastolic pressure and heighten their subjective perception of relaxation.     

Operant conditioning permits voluntary,noninvasive measurement of blood pressure in conscious,unrestrained baboons (Papio cynocephalus)

This report describes a computerized apparatus and procedure for completely automated noninvasive measurement of systolic, diastolic, and mean arterial blood pressure in conscious, unrestrained nonhuman primates. We used a specially constructed, cage-mounted oscillometric blood pressure instrument and operant reward conditioning methods to train adult baboons(Papio cynocephalus) to submit voluntarily to frequent self-initiated determinations of their blood pressures in the absence of a human operator/observer. Details concerning the operant training procedure and illustrative blood pressure data are presented. The accuracy of the method was evaluated by comparing the noninvasive blood pressure readings with simultaneously taken direct measurements obtained by means of chronically indwelling arterial catheters.     

Caffeine enhances the physiological response to occupational stress in medical students

Caffeine (3.3 mg/kg) was tested against a placebo in 20 male medical students during periods of low (no exams) versus high (final exams) work stress. On each of 8 test days, heart rate and blood pressure were measured at baseline and over a 40-min postdrug interval; immediately afterward, blood was drawn to test plasma cortisol and serum lipid concentrations. Exams increased heart rate (p less than .005) and systolic blood pressure (p less than .02). Caffeine decreased heart rate (p less than .0001) and increased systolic blood pressure (p less than .005), diastolic blood pressure (p less than .0001), plasma cortisol levels (p less than .01), and serum cholesterol levels (p less than .02). Caffeine effects were additive with those of exams, and together they increased the number of men showing systolic blood pressures in the borderline hypertensive range. Thus, caffeine use during periods of increased occupational stress may enhance the cumulative stress response.     

Effects of discrimination training on reading improvement among adults

This study examined the effects of discrimination training on improving reading skills for young adults. 90 college students (M age = 26.2 yr.), who were identified as low achievers with below average reading skills, were randomly assigned to one of three training conditions: the General Discrimination Group, the Reading Discrimination Group, and the Study Skills Group. Following 10 days of training, the subjects were tested on a standard reading achievement test, a problem-solving test, and a measure of cognitive style. Minimal differences between the pre- and posttraining scores for all three training conditions were noted. These findings contrast with developmental research that has indicated the importance of discrimination ability and suggest distinctive problems of adults with poor reading skills.     

Reliability and validity of portable blood pressure/pulse units during a competitive challenge

The aim of the present study was to determine the reliability and validity of recordings from three portable blood pressure/pulse units compared with simultaneous recordings from a polygraph used as the standard for these comparisons. The units tested included the Sears Digital Z153, Industrial Biomedical Sensor (IBS) Digital SD-700, and the Sphygmostat B-350/PU-102 (analog scale). Thirty healthy subjects were exposed to Pac-Man video game and mental arithmetic stressors. Each stressor was preceded by relaxation and followed by recovery periods. During each period, systolic/diastolic blood pressure and pulse were taken from one of the three portable units and the polygraph. The three units were reliable in recording systolic and diastolic blood pressure and heart rate across baseline, stressor, and recovery periods. The blood pressure/pulse readings from the digital units by Sears and IBS corresponded more closely to simultaneous polygraph recordings than did the analog scale device by Sphygmostat. These results suggest that the digital blood pressure/pulse units employed in this investigation are reliable and valid measurement devices suitable for field research with clinical populations.     

Familial similarity in Type A behaviour and physiological measurements as related to sex

Thirty-one families with pre-school children were examined with regard to Type A behaviour and cardiovascular and neuroendocrine measurements. Type A scores (MYTH) of the children from the ages of three to six were positively correlated with independent Type A measurements (Jenkins Activity Survey, Bortner Type A scale) of the parents (significant for fathers but not for mothers). The children's resting systolic blood pressures were significantly correlated with maternal and paternal values, while no significant familial aggregation was found for diastolic blood pressure, heart rate, catecholamine or cortisol excretion. The children's systolic and diastolic blood pressures and adrenaline excretion were significantly correlated between ages three and six. The results are consistent with the assumption that genetic as well as environmental factors contribute to the development of Type A behaviour. No significant association was found between Type A scores and physiological measurements during routine activities in the children or the adults.     

Instrumental conditioning of blood pressure elevations in the baboon

Two adult male baboons were surgically prepared with arterial catheters which provided a continuous measure of blood pressure and heart rate. Environmental consequences (food and electric shock) were made contingent upon prespecified increases in diastolic blood pressure levels. Continued exposure to these contingencies resulted in substantial increases in both diastolic and systolic pressures. The results demonstrated that blood pressure changes are highly susceptible to both operant“shaping” and stimulus control procedures and extend the range of instrumental conditioning effects upon the cardiovascular system.     

ACQUISITION,DISCRIMINATIVE STIMULUS CONTROL,AND RETENTION OF INCREASES/DECREASES IN BLOOD PRESSURE OF NORMOTENSIVE HUMAN SUBJECTS1

The aims of this study of 24 normotensive subjects were: to compare a free-operant with a discrete-trials training format; to determine the most effective training procedure by comparing instrumental conditioning with instructional set and a control; to see if both increases and decreases in blood pressure could be brought under discriminative control, and to examine the maintenance of acquired self-control of blood pressure. A 2 × 3 design was employed in which two trial formats (free operant and discrete trials) were factorially compared with three training conditions (instrumental conditioning, instructional set, and control). Instrumental conditioning was found superior to both the instructional set and control conditions in producing increases and decreases in mean diastolic blood pressure. The free-operant format led to a greater degree of learned BP control in that subjects were able to increase and decrease their blood pressure by 10% to 15% of basal value and to maintain the blood-pressure operant after contingent auditory feedback/reinforcement was removed. Training was discontinued when subjects in the other five groups failed to reach criterion after 10 consecutive acquisition sessions.     

Selective autonomic blockade of conditioned and unconditioned cardiovascular changes in rhesus monkeys (Macaca mulatta).

Changes in heart rate and in systolic and diastolic blood pressures were examined in eight rhesus monkeys during six sessions of differential classical conditioning. The conditioned stimuli consisted of tones differing in frequency and the unconditioned stimuli consisted of tail shock. Both the conditioned responses (CRS) and unconditioned responses (UCRs) consisted of increases in heart rate and in systolic and diastolic pressures, but blood pressure CRs sometimes occurred in the absence of heart rate CRs. Graded doses of the selective blocking agents propranolol, phentolamine, and atropine methylnitrate were systemically administered to four of the monkeys prior to additional conditioning sessions. The results suggested that the CRs and UCRs were mediated by both sympathetic and parasympathetic influences.     

Task-related arousal of type A and type B persons: level of challenge and response specificity

To determine whether different levels of challenge had differential effects on the arousal levels of Type A and Type B persons, 30 Type A and 30 Type B male subjects worked on an intelligence test task (digits backwards recall) that was easy, moderately difficult, or extremely difficult. Arousal was measured in terms of systolic blood pressure, diastolic blood pressure, pulse rate, pulse volume, skin resistance, and subjective arousal. Results indicated that while working on the extremely difficult task, the Type A subjects evidenced reliably higher systolic blood pressure than did the Type B subjects (p = 0.1; difference = 7.52 mm of Hg) and that there were not reliable differences between the subjects in systolic blood pressure at other levels of challenge or on other measures of arousal.     

An effect of linguistic experience: The discrimination of [r] and [l] by native speakers of Japanese and English

To test the effect of linguistic experience on the perception of a cue that is known to be effective in distinguishing between [r] and [l] in English, 21 Japanese and 39 American adults were tested on discrimination of a set of synthetic speech-like stimuli. The 13 “speech” stimuli in this set varied in the initial stationary frequency of the third formant (F3) and its subsequent transition into the vowel over a range sufficient to produce the perception of [r a] and [l a] for American subjects and to produce [r a] (which is not in phonemic contrast to [l a ]) for Japanese subjects. Discrimination tests of a comparable set of stimuli consisting of the isolated F3 components provided a “nonspeech” control. For Americans, the discrimination of the speech stimuli was nearly categorical, i.e., comparison pairs which were identified as different phonemes were discriminated with high accuracy, while pairs which were identified as the same phoneme were discriminated relatively poorly. In comparison, discrimination of speech stimuli by Japanese subjects was only slightly better than chance for all comparison pairs. Performance on nonspeech stimuli, however, was virtually identical for Japanese and American subjects; both groups showed highly accurate discrimination of all comparison pairs. These results suggest that the effect of linguistic experience is specific to perception in the “speech mode.”     

Cardiovascular generalization and differentiation: The relationship between heart rate and blood pressure

The present study was designed to study generalization and differentiation and to check the relation between heart rate and blood pressure in cardiovascular conditioning. Five naive mongrel dogs were presented with 10 sec 1000 cps tone regularly reinforced with 0.5-sec shock to a left foreleg. Four other 10-sec tones (600, 800, 1200, 1400 cps), never reinforced, were administered in a randomized and counterbalanced fashion using a differential reinforcing technique. The response measures were heart rate and three indices of blood pressure,i.e., systolic, diastolic, and pulse pressures.“Initial response” of heart rate showed rapid tachycardia to all tones, with no generalization and differentiation among five tones.“Terminal response” clearly indicated generalization gradients that tachycardia to 800 and 1200 cps tones were higher than those to 600 and 1400 cps tones, respectively. Some differences were noted among systolic, diastolic, and pulse pressures, with pulse pressure showing a trend of generalization and differentiation in the“initial response.” No statistical difference, however, was obtained in blood pressure scores. Beat-by-beat analyses of correlations between heart rate and diastolic blood pressure showed that the correlations successively decreased during the“terminal response.” Overall correlations between heart rate and three indices of blood pressure were obtained, with the highest correlation between heart rate and pulse pressure. Considering the above results in relation to the classical conditioning theory, it was tentatively concluded that“initial response” includes non-conditional factors, while“terminal response” reflects mainly a true conditional response, particularly, at a long CS-US interval. This interpretation leads to the hypothesis that conditional response with a short CS-US interval may attain better conditioning scores in terms of the summation effect between a non-conditional factor and a true conditional factor.     

Effect of Relaxation Therapy in Reducing Blood Pressure of Essential Hypertension Patients

The study investigated the effect of relaxation therapy on arterial blood pressure of Patients with essential hypertension. Ten known essential hypertension patients (males = 3; females = 7, age range 41–70, mean age 57.2 years, SD = 9.93 years) were sampled randomly from Medical outpatient department of the State owned University teaching Hospital in Ebonyi State South East, Nigeria. These Participants were exposed to 30 minutes relaxation therapy and their blood pressures were taken before and after the treatment. Using matched t test to compare baseline and post treatment scores, result showed that relaxation therapy progressively decreased both diastolic and systolic blood pressure readings of the Participants. The study concluded that Relaxation therapy can transiently lower the systolic and diastolic blood pressure.     

Blood pressure responses to hypnotic and nonhypnotic suggestions in normotensive subjects

Forty normotensive subjects participated on a voluntary basis in a study designed to compare the effect of suggestions on blood pressure (BP). Two experimental groups received suggestions presumed to be specific in lowering or raising BP after simple relaxation (relaxation group) or hypnotic induction (hypnotic group). A control group was used to record the BP changes over time. The time variable was significant for both systolic (SBP) and diastolic blood pressure (DBP). Induction procedures (hypnosis or relaxation) resulted in significant decreases in DBP in both experimental groups. In the control group there was a significant decrease in SBP. A specific suggestion to increase the BP resulted only in DBP increase in the hypnotic group. This group also gave an increase of both SBP and DBP over the entire experiment, whereas the relaxation group resulted in a significant decrease in SBP. There was no significant group variable, indicating no differences between the groups. Further research is needed to enable firm conclusions of the effect of suggestions on BP.     

Differentiation of fear, anger, and joy.

The purpose of the present study was to identify the physiological characteristics corresponding to three affects (fear, anger, and joy), which were elicited through real situations in a laboratory. The subjects were asked to rate their psychological responses using the Affect Rating Scales for each affective situation. Physiological indices (diastolic and systolic blood pressures, heart rate, respiration rate and frequency of galvanic skin response) were measured. The subjects' affects can be characterized by two functions obtained through discriminant analysis. One discriminant function separated positive from negative affects; the other set apart anger from the remaining affects.     

Are changes in blood pressure and total cholesterol related to changes in mood? An 18-month study of men and women.

The authors investigated the within-person association of reported mood with blood pressure and total cholesterol (TC) levels, each assessed 4 times over an 18-month period in 128 men and 154 women. Change over time in tense arousal was significantly positively associated with changes over time in systolic blood pressure (SBP) and diastolic blood pressure (DBP) but not TC. A change in hedonic tone was significantly associated with SBP (an increase in negative affect was associated with an increase in SBP) but not with DBP or TC. There were no sex differences in associations of mood with SBP or TC. However, increases in tense arousal and negative affect were significantly associated with an increase in DBP for women but not men.