发展性阅读障碍的ERP研究

发展性阅读障碍,ERP,语音缺陷假说,Oddball范式。行为实验已经发现,语音能力的缺损是拼音文字发展性阅读障碍的核心。然而近年来行为研究和神经生理学的研究也发现,发展性阅读障碍与基本知觉障碍有关。事件相关电位（event-related potentials ,简称ERP）作为一种独特的电生理学研究手段,从一个更为直观的角度验证了行为实验的结果,推动了发展性阅读障碍的进展。语言认知水平ERP研究表明,发展性阅读障碍者在存在语音加工和信息整合的缺陷。感知觉加工层次的ERP研究结果则不尽一致,有的研究发现,阅读障碍存在着基本的听觉加工缺陷;有的研究则发现发展性阅读障碍存在言语声音加工的缺陷,而对非言语声音的加工与正常读者没有显著差别;有的研究支持大细胞通路受损假说,发现阅读障碍在低对比度和低空间频率上存在视觉加工的缺陷,有的研究结果则没有发现发展性阅读障碍者与正常读者在不同对比度和空间频率上的差异。     

汉-英儿童双语者母语和二语加工的相互作用:来自神经机制方面的证据

双语者语言加工的神经机制一直是语言认知神经科学研究关注的热点问题之一。前人研究多关注二语加工过程,较少研究母语加工神经网络与二语加工神经网络之间的相互作用;并且前人研究多以成人为被试,研究结果可能会受到发展成熟因素的影响。本研究中,28名汉英儿童双语者进行了两种语言条件下的语音判断任务和字形判断任务,在进行任务的同时进行了磁共振扫描。通过全脑分析、感兴趣区分析和相关分析,结果显示:1)汉语语音、字形加工和英语语音、字形加工激活了类似的脑区网络,但也存在差异。汉语特异脑区(根据Tan等人对汉英跨语言比较的元分析进行定义)右侧枕下回、梭状回以及左侧扣带回在英语语音、字形任务中都显著激活,英语语音任务还额外激活了汉语特异的左脑额中回和中央前回;英语特异脑区(根据Tan等人对汉英进行跨语言比较的元分析进行定义)左脑额内侧、额下回以及梭状回在汉语语音、字形加工中显著激活。2)儿童的英语熟练度越低,左脑扣带回(汉语特异脑区)在汉语语音和汉语字形任务中的激活越强;汉语熟练度越高,左脑额下回(英语特异脑区)在英语字形任务中的激活越强,左脑颞上回(英语特异脑区)在英语语音任务中的激活越弱。两个任务的结果一致说明:汉英双语者母语加工的神经网络与二语加工的神经网络之间存在相互作用,并且受到双语熟练度的调制。     

发展性阅读障碍亚类型研究进展

发展性阅读障碍是一种特殊的学习障碍,伴有多种认知缺陷并且存在不同的亚类型。依据相关的阅读模型理论,阅读障碍可划分为语音型和表层型。从认知缺陷角度出发,语音加工缺陷是主要的缺陷表现,以此为特征形成一种主要的阅读障碍的亚类型,同时还有以正字法加工缺陷和快速命名缺陷为主的其他亚类型。而以基本感知觉缺陷为标准,主要有以视觉加工缺陷和以听觉加工缺陷为主的两种亚类型。在汉语条件下,依据同样的阅读模型理论,语音型阅读障碍亚类型比例明显低于拼音文字条件下的。汉语阅读障碍也具有分别以语音加工缺陷、快速命名缺陷和正字法加工缺陷为主要认知缺陷的亚类型。未来有必要从神经机制角度进一步明确不同亚类型的神经基础。     

发展性阅读障碍的理论及眼动研究

关于发展性阅读障碍,国外研究者,基于认知和生物因素,先后提出了语音缺陷论、小脑缺陷论、一般性大细胞功能障碍论等对发展性阅读障碍进行解释,并考察了患者的眼动特征,提出了有效的诊治方法。目前,汉语发展性阅读障碍研究主要局限在语音和正字法领域,也涉及局部脑区的功能缺陷,但还未从多角度测查其成因,如眼动。这里,在理论梳理的基础上,系统探讨了发展性阅读障碍者的眼动特征,如注视时间、注视次数、眼跳、回视等,及视觉加工的眼动机制     

汉语阅读障碍的语音加工及正字法加工缺陷的实验研究

本研究对汉语阅读障碍的加工缺陷进行探讨,期望有助于揭示语言加工的普遍性与特殊性,以及阅读障碍的成因,并可为后期的干预提供帮助。研究采用改编的言语认知测验对阅读水平匹配组与阅读障碍组和生理年龄匹配组进行比较后发现,阅读障碍组在语音意识和正字法加工任务上的成绩均明显差于生理年龄控制组和阅读水平匹配组;阅读障碍组在快速命名和语音记忆任务上的成绩不如生理年龄匹配组,仅达到阅读水平匹配组水平。因此,汉语发展性阅读障碍儿童存在语音意识和正字法加工缺陷,这两种缺陷可能是阅读障碍儿童面临的最主要的两大缺陷;阅读障碍儿童在快速命名和语音记忆上的不足可能是发展迟滞所致。同时,大多数的汉语阅读障碍儿童存在不止一种的认知缺陷。阅读障碍儿童在语音意识和正字法加工上存在缺陷的比例最高。     

发展性阅读障碍的视觉拥挤效应

发展性阅读障碍的核心缺陷一直是研究者关注的焦点。近年来,国内外大量研究发现视觉加工缺陷可能是导致阅读障碍的一个重要原因,其中视觉拥挤效应与阅读障碍密切相关。本文将回顾视觉拥挤效应的概念及其理论基础、拼音文字和汉语阅读障碍者视觉拥挤效应的相关研究,提出汉语阅读障碍视觉拥挤效应研究的未来发展方向,以便更好地了解汉语阅读障碍与视觉拥挤效应之间的关系。     

发展性阅读障碍的视觉拥挤效应

发展性阅读障碍的核心缺陷一直是研究者关注的焦点。近年来,国内外大量研究发现视觉加工缺陷可能是导致阅读障碍的一个重要原因,其中视觉拥挤效应与阅读障碍密切相关。本文将回顾视觉拥挤效应的概念及其理论基础、拼音文字和汉语阅读障碍者视觉拥挤效应的相关研究,提出汉语阅读障碍视觉拥挤效应研究的未来发展方向,以便更好地了解汉语阅读障碍与视觉拥挤效应之间的关系。     

发展性阅读障碍书写加工缺陷及其神经机制

发展性阅读障碍是学习障碍的主要类型之一, 严重影响个体认知、情感与社会适应性的发展。书写与阅读关系密切, 阅读障碍者常常表现出书写加工缺陷。在行为层面, 阅读障碍者书写缺陷表现在书写质量差、速度慢和停顿多等多个方面。在脑机制层面, 脑成像研究发现, 阅读障碍者书写加工缺陷与字形加工脑区活动, 以及字形与运动区脑功能与结构连接异常有关。总体而言, 阅读障碍者书写过程中的字形通达缺陷的证据比较充分, 但字形与运动编码的衔接以及运动执行是否存在困难, 尚缺乏研究证据。相对于字母语言, 书写与阅读的关系在汉语中更为紧密, 汉语阅读障碍的书写研究将为开发汉语特色的诊治方案提供重要指导。     

发展性阅读障碍的注意缺陷研究现状

近年来,发展性阅读障碍的注意缺陷研究逐渐受到重视.行为实验发现,阅读障碍者有多种注意缺陷现象,主要表现为“视野不对称性”和“注意转换延迟”.脑电研究表明,阅读障碍的注意缺陷与大脑后顶叶皮层功能异常有关.大细胞通路假设认为,阅读障碍的视知觉缺陷来源于视觉大细胞受损,大细胞通路所加工的信息主要投射到靠近颞枕顶联合区的V5MT区,这个脑区为后顶叶皮层提供大量投射.因此,阅读障碍的注意缺陷与大细胞通路受损存在一定关系.     

新生儿语音感知的神经基础:元分析

语言习得能力是人类在进化中获得的重要能力之一。语言认知的核心功能是语音加工, 因此, 语音加工的脑机制是认知心理学研究的重要课题。我们采用元分析方法, 对使用近红外技术考察新生儿语音感知的结构检测、偏差检测和母语感知的研究进行系统的定量分析, 探究新生儿的典型语音感知脑机制以及这三类语音加工相关脑区的异同。结果显示, 左侧额下回是新生儿检测语音结构的关键脑区; 双侧颞叶在新生儿语音偏差刺激检测中发挥关键作用; 新生儿的母语语音加工存在左侧化优势。     

Temporal processing and phonological impairment in dyslexia: effect of phoneme lengthening on order judgment of two consonants

The evidence of supporting phonological deficit as a cause of developmental dyslexia has been accumulating rapidly over the past 2 decades, yet the exact mechanisms underlying this deficit remain controversial. Some authors assume that a temporal processing deficit is the source of the phonological disorder observed in dyslexic children. Others maintain that the phonological deficit in dyslexia is basically linguistic, not acoustic, in nature. Three experiments were conducted and tested the impact of the temporal alteration and the impact of complex syllabic structure on consonant order judgments. Thirteen phonological dyslexics (age 10-13) and 10 controls matched for chronologial age were compared on a Temporal Order Judgment (TOJ) task using the succession of two consonants (/p/ /s/) within a cluster. In order to test the possible relevance of the temporal deficit hypothesis, the task also included two additional conditions where either the two stimuli were artificially slowed or two phonological structures were opposed (CCV and CVCV). As expected, the TOJ performance was significantly poorer in dyslexics than in controls. Moreover, in the "slowed speech" condition dyslexics' performance improved to reach the normal controls' level, whereas manipulating the phonological structure complexity provided no significant improvement. Finally dyslexics' performances, especially on the slowed condition, were found correlated with several tests of phonological processing. These results lend support to the general temporal deficit theory of dyslexia.     

Dyslexia and dyscalculia: Two learning disorders with different cognitive profiles

This study tests the hypothesis that dyslexia and dyscalculia are associated with two largely independent cognitive deficits, namely a phonological deficit in the case of dyslexia and a deficit in the number module in the case of dyscalculia. In four groups of 8- to 10-year-olds (42 control, 21 dyslexic, 20 dyscalculic, and 26 dyslexic/dyscalculic), phonological awareness, phonological and visual-spatial short-term and working memory, naming speed, and basic number processing skills were assessed. A phonological deficit was found for both dyslexic groups, irrespective of additional arithmetic deficits, but not for the dyscalculia-only group. In contrast, deficits in processing of symbolic and nonsymbolic magnitudes were observed in both groups of dyscalculic children, irrespective of additional reading difficulties, but not in the dyslexia-only group. Cognitive deficits in the comorbid dyslexia/dyscalculia group were additive; that is, they resulted from the combination of two learning disorders. These findings suggest that dyslexia and dyscalculia have separable cognitive profiles, namely a phonological deficit in the case of dyslexia and a deficient number module in the case of dyscalculia.     

Naming problems do not reflect a second independent core deficit in dyslexia: Double deficits explored

The double deficit hypothesis states that naming speed problems represent a second core deficit in dyslexia independent from a phonological deficit. The current study investigated the main assumptions of this hypothesis in a large sample of well-diagnosed dyslexics. The three main findings were that (a) naming speed was consistently related only to reading speed; (b) phonological processing speed and naming speed loaded on the same factor, and this factor contributed strongly to reading speed; and (c) although general processing speed was involved in speeded naming of visual items, it did not explain the relationship between naming speed and reading speed. The results do not provide support for the existence of a second independent core naming deficit in dyslexia and indicate that speeded naming tasks are mainly phonological processing speed tasks with an important addition: fast cross-modal matching of visual symbols and phonological codes.     

What phonological deficit?

We review a series of experiments aimed at understanding the nature of the phonological deficit in developmental dyslexia. These experiments investigate input and output phonological representations, phonological grammar, foreign speech perception and production, and unconscious speech processing and lexical access. Our results converge on the observation that the phonological representations of people with dyslexia may be intact, and that the phonological deficit surfaces only as a function of certain task requirements, notably short-term memory, conscious awareness, and time constraints. In an attempt to reformulate those task requirements more economically, we propose that individuals with dyslexia have a deficit in access to phonological representations. We discuss the explanatory power of this concept and we speculate that a similar notion might also adequately describe the nature of other associated cognitive deficits when present.     

英语发展性阅读障碍的训练程序

英语发展性阅读障碍的成因解释有三种倾向：基于语言的,非语言的,以及二者兼有的。语言学取向者认为障碍发生在语言学层次上,尤其是语音障碍;非语言学取向者认为有着更基本的视听知觉障碍,尤其是听觉时间加工缺陷;基于流畅性的双重障碍假说则认为二者兼有。根据这三类假设,研究者们开发了与之相应的基于语音意识缺陷、听觉时间加工缺陷和双重障碍的训练方案,其设计思路、材料选择和程序安排,对中文发展性阅读障碍的训练研究,有一定参考价值     

汉语发展性阅读障碍亚类型的初步探讨

以阅读水平匹配组为参照对29名汉语发展性阅读障碍儿童的认知缺陷模式进行了分析,并考察了不同亚类型阅读障碍儿童的汉字识别模式。结果表明汉语发展性阅读障碍存在不同的亚类型,以语音缺陷型、快速命名缺陷型及两者结合的双重缺陷型为主,与英语国家研究中的双重缺陷假设一致。语音缺陷型儿童汉字识别时有更多的语义错误,对声旁中的部分语音线索不敏感;快速命名缺陷型儿童汉字识别时依赖声旁语音线索,表现出阅读发展的一般延迟;双重或多重认知缺陷型是阅读损伤最严重的亚类型     

Spanish developmental dyslexia: Prevalence, cognitive profile, and home literacy experiences

This study was designed to examine the prevalence, cognitive profile, and home literacy experiences in subtypes of Spanish developmental dyslexia. The subtyping procedure used comparison with chronological-age-matched and reading-level controls on reaction times and accuracy responses to high-frequency words and pseudowords. Using regression-based procedures, 8 phonological dyslexics and 16 surface dyslexics were identified from a sample of 35 dyslexic fourth graders by comparing them with chronological-age-matched controls on reaction times to high-frequency word and pseudoword reading. However, when the dyslexic subtypes were defined by reference to reading-level controls, 12 phonological dyslexics were defined but only 5 surface dyslexics were identified. Both dyslexic subtypes showed a deficit in phonological awareness, but children with surface dyslexia also showed a deficit in orthographical processing assessed by a homophone comprehension task. This deficit was associated with poor home literacy experiences, with the group of parents with children matched in reading age, in comparison with the group of parents with children with surface dyslexia, reporting more literacy home experiences.     

Phonological dyslexia: a test case for reading models

Following brain damage, skilled readers may encounter more severe problems in reading nonwords than familiar words, a type of deficit referred to as phonological dyslexia. We report on 2 individuals with Alzheimer's disease who show phonological dyslexia. Although highly accurate in reading familiar words aloud (even those with irregular spelling, such as sew), they were quite impaired in nonword reading. Both patients performed well in phonological tasks involving the repetition, identification, and manipulation of phonemes of orally presented words and nonwords. These results challenge the idea, proposed in the context of connectionist and evolutionary theories, that phonological dyslexia originates from a phonological deficit. However, the results are consistent with reading models, such as the dual-route model, that attribute phonological dyslexia to a deficit that selectively affects the reading mechanisms responsible for deriving the sounds of nonwords. According to these models, such a deficit is not necessarily accompanied by a more general phonological impairment.     

Speech prosody and developmental dyslexia: Reduced phonological awareness in the context of intact phonological representations

Recent research indicates that awareness of the rhythmic patterns present in spoken language (i.e., prosody) may be an important and relatively overlooked predictor of reading ability. Two studies investigated the prosodic processing abilities of skilled adult readers and adults with developmental dyslexia. Participants with dyslexia showed reduced awareness of lexical and metrical stress and these skills were found to be significantly associated with, and predictive of, phonological decoding ability. In contrast, the same individuals showed normal patterns of stress based priming at magnitudes similar to controls. These results—suggesting reduced phonological awareness in the context of intact phonological representations—are consistent with recent findings reported in the domain of phonemic processing. Implications for the phonological deficit theory of dyslexia are discussed.