Body–Mind Integrality: Remarks on the Nature and Origin of Universe and Life

This article summarizes scientific knowledge in the fields of quantum physics and medical science regarding the origin and the nature of the universe and life. The recent discoveries in the fields of biophysics, genetics, epigenetics, neuroscience, and psychosomatics describe the universe and life as highly coherent systems where information is a key factor. In this concept living systems are cognitive networks in a dynamic relationship with their environment. Health in this context is a dynamic balance in a subject in which the information flows functionally. Disease is identified as a pathology of information that can be classified in a new way, considering two different codes of meaning—the semiotic and the symbolic.     

Symmetry-breaking dynamics in development

Recognition of the plasticity of development — from gene expression to neuroplasticity — is increasingly undermining the traditional distinction between structure and function, or anatomy and behavior. At the same time, dynamic systems theory — a set of tools and concepts drawn from the physical sciences — has emerged as a way of describing what Maurice Merleau-Ponty calls the “dynamic anatomy” of the living organism. This article surveys and synthesizes dynamic systems models of development from biology, neuroscience, and psychology in order to propose an integrated account of growth, learning, and behavior. Key to this account is the concept of self-differentiation or symmetry-breaking. I argue that development can be understood as a cascade of symmetry-breaking events brought about by the ongoing interactions of multiple, nested, nonlinear dynamic systems whose self-organizing behaviors gradually alter their own anatomical conditions. I begin by introducing the concept of symmetry-breaking as a way of understanding anatomical development. I then extend this approach to motor development by arguing that the organism’s behavior grows along with its body, like a new organ. Finally, I argue that the organism’s behavior and its world grow together dialectically, each driving the other to become more complex and asymmetrical through its own increasing asymmetry. Thus development turns out to be a form of cognition or sense-making, and cognition a form of development.     

Divine Action,Resurrection, and the Transformation of the Universe

Abstract

The article examines the notion of self-organization and explores the reality of biological processes from an epistemological point of view. First, I briefly analyze what is currently regarded as one of the most important discoveries not only in physics, but also in biology—namely, complex systems and deterministic chaos; secondly, I offer some reflections on the new frontiers of contemporary biology— namely, functional genomics and systems biology. The central part of the article focuses on the epistemological transition from genetic determinism to the new conception of “meaning” as emergence.     

Strategies of model-building in condensed matter physics: trade-offs as a demarcation criterion between physics and biology?

This paper contrasts and compares strategies of model-building in condensed matter physics and biology, with respect to their alleged unequal susceptibility to trade-offs between different theoretical desiderata. It challenges the view, often expressed in the philosophical literature on trade-offs in population biology, that the existence of systematic trade-offs is a feature that is specific to biological models, since unlike physics, biology studies evolved systems that exhibit considerable natural variability. By contrast, I argue that the development of ever more sophisticated experimental, theoretical, and computational methods in physics is beginning to erode this contrast, since condensed matter physics is now in a position to measure, describe, model, and manipulate sample-specific features of individual systems—for example at the mesoscopic level—in a way that accounts for their contingency and heterogeneity. Model-building in certain areas of physics thus turns out to be more akin to modeling in biology than has been supposed and, indeed, has traditionally been the case.     

THE FAULT IN US: ETHICS,INFINITY, AND CELESTIAL BODIES

Catherine Keller's Cloud of the Impossible knits together process theology and relational ontology with quantum mechanics. In quantum physics, she finds a new resource for undoing the architecture of classical metaphysics and its location of autonomous human subjects as the primary gears of ethical agency. Keller swarms theology with the quantum perspective, focusing in particular on the phenomenon of quantum entanglement, by which quantum particles are found to remain influential over each other long after they have been physically separated—what Albert Einstein and his collaborators recklessly dismissed as “spooky action at a distance.” This spooky action, Keller suggests, reroutes process thought—classically concerned with flux—to a new concern with intransigence—particularly the intransigence of the ethical relationship. Attending to the ethical urgency of the Other, she leaves process theology in a position of susceptibility to the moral imperative posed by the marginalized, the victimized, and the oppressed. This essay argues that although the ontological work of Keller's book productively integrates quantum physics into process theology, the ethical dimension of relationality is left cold in the quantum field. This is because, contra the ethical framework of contemporary deconstruction, which, following Emmanuel Levinas, sees ethical relationships as emerging out of a dynamic of infinite distance, moral connection has nothing to do with the remote reaches of the quantum scale or the macro‐scale limits of space—nothing to do with “infinity” at all. Ethics emerges out of a much messier landscape—the evolved dynamic of fleshy, finite, material bodies. Rather than seeing ethical labor as a matter of physics, my contention (and here I think I am arguing with, rather than against Keller) is that interdisciplinary undertakings like Cloud of the Impossible are ethical disciplinary practices, re‐acquainting us with the non‐sovereignty of the self in order to open up new habits of relating rather than spotlighting ethical imperatives.     

A Conceptual Construction of Complexity Levels Theory in Spacetime Categorical Ontology: Non-Abelian Algebraic Topology, Many-Valued Logics and Dynamic Systems

A novel conceptual framework is introduced for the Complexity Levels Theory in a Categorical Ontology of Space and Time. This conceptual and formal construction is intended for ontological studies of Emergent Biosystems, Super-complex Dynamics, Evolution and Human Consciousness. A claim is defended concerning the universal representation of an item’s essence in categorical terms. As an essential example, relational structures of living organisms are well represented by applying the important categorical concept of natural transformations to biomolecular reactions and relational structures that emerge from the latter in living systems. Thus, several relational theories of living systems can be represented by natural transformations of organismic, relational structures. The ascent of man and other living organisms through adaptation, is viewed in novel categorical terms, such as variable biogroupoid representations of evolving species. Such precise but flexible evolutionary concepts will allow the further development of the unifying theme of local-to-global approaches to highly complex systems in order to represent novel patterns of relations that emerge in super- and ultra-complex systems in terms of compositions of local procedures. Solutions to such local-to-global problems in highly complex systems with ‘broken symmetry’ might be possible to be reached with the help of higher homotopy theorems in algebraic topology such as the generalized van Kampen theorems (HHvKT). Categories of many-valued, ?ukasiewicz-Moisil (LM) logic algebras provide useful concepts for representing the intrinsic dynamic ‘asymmetry’ of genetic networks in organismic development and evolution, as well as to derive novel results for (non-commutative) Quantum Logics. Furthermore, as recently pointed out by Baianu and Poli (Theory and applications of ontology, vol 1. Springer, Berlin, in press), LM-logic algebras may also provide the appropriate framework for future developments of the ontological theory of levels with its complex/entangled/intertwined ramifications in psychology, sociology and ecology. As shown in the preceding two papers in this issue, a paradigm shift towards non-commutative, or non-Abelian, theories of highly complex dynamics—which is presently unfolding in physics, mathematics, life and cognitive sciences—may be implemented through realizations of higher dimensional algebras in neurosciences and psychology, as well as in human genomics, bioinformatics and interactomics.     

The Principle of Necessity,and the Necessity of Principle: Commentary on Steven Stern’s Paper “Holistic Thinking and Therapeutic Action: Building on Louis Sander’s Contribution”

Steven Stern’s principle of necessity underscores the importance of being open to the emergence of something new, something therapeutically vital and alive to both patient and therapist, requiring a unique alertness to the unbidden, the previously not-thought-about, the on-the-edges-of-our-experience type impressions in the course of living through the otherwise familiar and the usual. This commentary addresses Stern’s principle of necessity and, equally so, the continuing necessity of principle in analytic work—a kind of ongoing sensibility that argues for placing aside theoretical knowledge and intervention categories in favor of striving to be open to the emergence of the unusual and the unexpected, to what ultimately proves therapeutic. We strive to work at and tolerate suspending our preconceptions, our theories, and our assumptions about how things should unfold in the clinical setting—what is referred to as analytic courage.     

THE CONSEQUENCES OF METAPHYSICS: OR,CAN CHARLES PEIRCE'S CONTINUITY THEORY MODEL STUART KAUFFMAN'S BIOLOGY?

At the heart of the most radical proposals in Stuart Kauffman's Investigations is his attempt to show that we find in evolutionary biology some configuration spaces—the sets of possible developments for any given system—that (unlike those in traditional physics of Newtonian, relativistic, and quantum stripes) cannot be completely described in advance. We bring Charles Peirce's work on the philosophy of continuity to bear on the problem and discover, first, that Kauffman's arguments do not succeed; second, that Peirce's metaphysics provide new and sounder arguments for the same propositions; third, that Peirce's rigorous but nonstandard treatment of mathematical continuity shows great promise for modeling the unpredictability and growth we find in evolutionary biology; fourth, that it also strengthens a development only hinted at by biologists thus far—the inevitable involvement of the observer's mind in constituting the objects of science. We close with a logical argument for the surprising relevance of metaphysical hypotheses in the natural sciences and with suggestions for future work that will connect these questions to what Kauffman terms the “narrative stance” in biology.     

Louis Sander and Contemporary Psychoanalysis: Nonlinear Dynamic Systems,Developmental Research,Clinical Process and the Search for Core Principles

ABSTRACT

Louis Sander’s cutting-edge approach drew on infant observation research; nonlinear dynamic systems theories; and current biology, physics, and other hard sciences. From this vantage point, he rethought the psychoanalytic approach to psychic structure, motivation, and therapeutic action. He opened a window for a broad and inclusive relational metapsychology of the highest order, updating Freud’s project of linking psychoanalysis with scientific paradigms. Sander emphasized the dynamic relationships between elements in systems, innovating in both method and content. This article offers an account of Sander’s broad and deep integration of psychoanalysis and developmental research.     

Élan Vital Revisited: Bergson and the Thermodynamic Paradigm

The received view of Bergson's philosophy of life is that it advances some form of vitalism under the heading of an “élan vital.” This paper argues against the vitalistic interpretation of Bergson's élan vital as it appears in Creative Evolution (1907) in favor of an interpretation based on his overlooked reflections on entropy and energetics. Within the interpretation developed here, the élan vital is characterized not as a spiritualistic “vital force” but as a tendency of organization opposed to the tendency of entropic degradation. It is then shown how Bergson's view of evolution and living organization resonates with more contemporary scientific approaches belonging to a “thermodynamic paradigm” in theoretical biology in different respects, including the critique of neo‐Darwinism and the positing of a driving force behind evolution. Finally, the special interest that Bergson's philosophical biology bears today is considered in terms of the connection between the concepts of élan vital and duration.     

TELEOLOGY PAST AND PRESENT

Abstract. Current teleology in Western biology, philosophy, and theology draws on resources from four main Western philosophers. (1) Plato's Timaeus shows how to interpret the universe as the handiwork of a purposive Creator who subordinates secondary, necessary, causes to primary, intelligent, causes. (2) Aristotle's Physics sets forth purpose as implicit in the nature of things. Purposes of different sorts inhere in different types of being, and everything has a natural function. Living things grow to actualize the potentials of the goal whose principle they bear within themselves. (3) Kant's Critique of Judgment denies that purpose is anything that human beings can know, strictly speaking. Nevertheless, purpose is a concept we must use to make sense of biological systems. (4) Hegel's Philosophy of Nature articulates organic systems as dialectically including and transcending mechanical and chemical systems. Teleological themes persist, in different ways, in contemporary discussions; I consider two lines of criticism of traditional teleology—by Richard Dawkins and Stephen Jay Gould—and one line that continues traditional teleology in an updated way—by Holmes Rolston, III.     

The Relationality of Everyday Life: The Unfinished Journey of Relational Psychoanalysis

Building on the insights embodied in Stephen Mitchell’s critiques of the developmental tilt and the metaphor of the baby, this paper aims to further illuminate the limitations of theoretical models rooted in infantile prototypes and to point relational theory toward a more thoroughgoing understanding of the contextuality and relationality of every facet of our lives. In its examinations of both the mother–infant interaction and the intricacies of the analytic relationship, the relational turn has yielded deep insights into the reciprocal, two-person causal sequences that characterize the development and dynamics of personality. But in the massive zone of living that occurs outside the nursery or the consulting room—the countless interactions and experiences of everyday life—relational theory has made less of a contribution, implicitly relying on an older psychoanalytic model in which these events of daily life reflect or express inner dynamics, rather than highlighting how daily life experiences continue to shape the inner world even as the inner world gives meaning and shape to those ongoing experiences. Drawing on both parallels and differences between Mitchell’s seminal contributions and the theoretical perspective known as cyclical psychodynamics, the paper aims to extend relational advances in understanding the mother–infant matrix and the dynamic structure of the analytic relationship to the everyday events that constitute the vast majority of our waking hours. In doing so, it points to a consequentiality to everyday life that, when appreciated and taken seriously, opens new pathways for therapeutic advance and provides a more solid and comprehensive foundation for relational theory.     

Group life shapes the psychology and biology of health: The case for a sociopsychobio model

Engel presented a compelling case for a biopsychosocial model of health. This challenged a biomedical model that he saw as reductionistic, physicalistic, and exclusionist. Yet despite its laudable goals and popularity, the biopsychosocial model can be faulted for being incremental, imprecise, and individualistic. Ultimately, this means it is no less reductionist than the biomedical model which it sought to supplant. In this paper, we present a reformulation of this model that foregrounds the capacity for social groups—and the social contexts in which those groups are embedded—to structure psychology and, through this, biology and health. This sociopsychobio model argues that the three elements of Engel's framework are not fixed and immutable but rather dynamic and interdependent. The model is consistent with a range of recent approaches to health that have focused on the important role that social class, social inequality, social structure, and social networks play in shaping health outcomes. In this paper, though, the concrete value of this reformulation is illustrated through a discussion of recent research that focuses on the role of group memberships and associated social identities in shaping the psychology and biology of stress. This review underlines two key points that are central to the general case for a sociopsychobio model of health. First, that groups are a force in the world that shape the psychology and biology of their members (as well as members of other groups) in ways that cannot be reduced to those group members' functioning as individuals. Second, that groups provide their members with a basis for seeking to change the world rather than simply accepting it. In this, group life is not merely an appendage to psychology and biology but is instead a basis for collective experiences that have the potential to unleash new expressions of both.     

New Directions in the Conceptualization and Assessment of Personality—A Dynamic Systems Approach

In this paper, we demonstrate how an integrative approach to personality—one that combines within-person and between-person differences—can be achieved by drawing on the principles of dynamic systems theory. The dynamic systems perspective has the potential to reconcile both the stable and dynamic aspect of personality, it allows including different levels of analysis (i.e. traits and states), and it can account for regulatory mechanisms, as well as dynamic interactions between the elements of the system, and changes over time. While all of these features are obviously appealing, implementing a dynamic systems approach to personality is challenging. It requires new conceptual models, specific longitudinal research designs, and complex data analytical methods. In response to these issues, the first part of our paper discusses the Personality Dynamics model, a model that integrates the dynamic systems principles in a relatively straightforward way. Second, we review associated methodological and statistical tools that allow empirically testing the PersDyn model. Finally, the model and associated methodological and statistical tools are illustrated using an experience sampling methodology data set measuring Big Five personality states in 59 participants (N = 1916 repeated measurements). © 2020 The Authors. European Journal of Personality published by John Wiley & Sons Ltd on behalf of European Association of Personality Psychology     

The mereology of thermodynamic equilibrium

The special composition question (SCQ), which asks under which conditions objects compose a further object, establishes a central debate in modern metaphysics. Recent successes of inductive metaphysics, which studies the implications of the natural sciences for metaphysical problems, suggest that insights into the SCQ can be gained by investigating the physics of composite systems. In this work, I show that the minus first law of thermodynamics, which is concerned with the approach to equilibrium, leads to a new approach to the SCQ, the thermodynamic composition principle (TCP): Multiple systems in (generalized) thermal contact compose a single system. This principle, which is justified based on a systematic classification of possible mereological models for thermodynamic systems, might form the basis of an inductive argument for universalism. A formal analysis of the TCP is provided on the basis of mereotopology, which is a combination of mereology and topology. Here, “thermal contact” can be analyzed using the mereotopological predicate “self-connectedness”. Self-connectedness has to be defined in terms of mereological sums to ensure that scattered objects cannot be self-connected.

     

The Study of Socioethical Issues in Systems Biology

Systems biology is the rapidly growing and heavily funded successor science to genomics. Its mission is to integrate extensive bodies of molecular data into a detailed mathematical understanding of all life processes, with an ultimate view to their prediction and control. Despite its high profile and widespread practice, there has so far been almost no bioethical attention paid to systems biology and its potential social consequences. We outline some of systems biology's most important socioethical issues by contrasting the concept of systems as dynamic processes against the common static interpretation of genomes. New issues arise around systems biology's capacities for in silico testing, changing cultural understandings of life, synthetic biology, and commercialization. We advocate an interdisciplinary and interactive approach that integrates social and philosophical analysis and engages closely with the science. Overall, we argue that systems biology socioethics could stimulate new ways of thinking about socioethical studies of life sciences.     

From Validating to Verifying: Public Appeals in Synthetic Biology

Synthetic biology provides a vivid and richly entangled contemporary example of a science being made public. A science, however, can be made public in different ways. A public could validate, legitimate, de-legimate, object to, verify, confirm or dissent from science. Practically, scientists could publicise science—in the mass media—or they could make science public. The contrast between high-profile, media scientists such as J. Craig Venter, and community-based participatory mechanisms such as OpenWetWare allows us to see how these alternatives play out in practice. While it is easy to criticise and dismiss the public-relations oriented promotion of synthetic biology by figures such as Venter, how should we evaluate the open participatory mechanisms of a social media effort such as OpenWetWare? I suggest, drawing on the work of Isabelle Stengers and Michael Warner, that the case of synthetic biology is interesting because many synthetic biologists commit themselves to making it public, and making its public-ness part of how it is done. They place hope in publics to make the science viable. At the same time, however, the publics who are welcomed into OpenWetWare are largely confined to validating the coordination mechanisms on which the claim to public-ness rests. Whether publics can do more than validate synthetic biology, then, remains a question both for publics outside and inside this emerging scientific field. And whether the alternatives of validation or participation themselves adequately frame what is at stake in the emergence of fields such as synthetic biology remains debatable.     

Consciousness and Science: an Advaita-Vedantic Perspective on the Theology – Science Dialogue

In modern science, the synthesis of “nature/mind” in observation, experiment, and explanation, especially in physics and biology increasingly reveal a “non-linear” totality in which subject, object, and situation have become inseparable. This raises the interesting ontological question of the true nature of reality. Western science as seen in its evolution from Socratic Greece has tried to understand the world by “objectifying” it, resulting in dualistic dilemmas. Indian “Science,” as seen in its evolution from the Vedic times (1500—500 BCE) has tried to understand the world by “subjectifying” our consciousness of reality. Within the Hindu tradition, the Advaita-Vedanta school of philosophy offers possibilities for resolving not only the Cartesian dilemma but also a solution to the nature of difference in a non-dualistic totality. We also present the Advaita-Vedanta principle of superimposition as a useful approach to modern physical and social science, which have been increasingly forced to reject the absolute reductionism and dualism of classical differences between subject and object.     

Cosmic Mind?

This article explores the remote scientific possibility of something like “cosmic mind” or “cosmic minds.” Descartes proposed his famous dualism, res cogitans (mental reality) plus res extensa (physical reality). With Isaac Newton and classical physics, res extensa won in Western science and with it, we lost our minds; we lost our subjective pole. Quantum mechanics has seemed to many, since its formulation in the Schrödinger equation in 1926, to hint beyond physics to a role for the human conscious observer in quantum measurement. At least two interpretations of quantum mechanics, or its extension—the latter by Penrose and Hameroff, and the former by myself—suggest a new panpsychism where conscious awareness and possibly free will occur at quantum measurements anywhere in the universe. If so, then we live in a vastly participatory universe. More: entangled quantum variables may conceivably share some form of consciousness and free will, whether embodied in us, or living forms elsewhere in the universe, or disembodied; hence, something like cosmic mind or minds are not ruled out. If true, life anywhere in the universe will have evolved with mind and free will. Souls are not impossible.     

The Ontology of Mutualism

Abstract

The homeokinetic approach to behavior (applied to humans, the approach is described in Iberall & McCulloch, 1969; and more generally in Soodak & Iberall, 1978) is extended in this article to argue that free will is exercised at a temporal scale of approximately 6 s. The homeokinetic theory of complex physical systems, including living systems, analyzes activity into component sets of oscillators, action modes, each with a characteristic time scale. A full set of nested time scales involved can be thought of as a spectrum. In this article, I argue that a survey of human action modes, as a spectral analysis, allows for the free election of acts only at the 6-s scale.

Intention (per Hebb, see Wolman, 1973, p. 437): central guidance of behavior by an enduring system that maintains its independence despite sensory input. Volition: act of willing or choosing.

This article is concerned with establishing a physical foundation for such actions in mammals, particularly human.