From case management to prevention of scientific dishonesty in Denmark

In 1992, The Danish Medical Research Council established a national committee on scientific dishonesty with the twofold task of handling cases of scientific misconduct and taking preventive initiatives. Scientific dishonesty was proven in only five cases, but in another nine cases lesser degrees of deviations from good scientific practice were found. The experiences from a total of 24 treated cases indicated that three key areas were at the basis of most of the accusations and the deviations from good practice: uncertainty about 1) authorship, about 2) rights and duties to use scientific data and about 3) agreements at the initiation of joint studies. As a consequence guidelines on good practice have been issued on these key subjects. An earlier version of this paper was presented at a symposium, Scientific Misconduct. An International Perspective, organised by The Medical University of Warsaw, 16 November, 1998.     

Reviews

Books reviewed: Science and Theology: An Introduction, by JohnPolkinghorne Genesis, Genes, and God: Values and Their Origins in Naturaland Human History, by Holmes Rolston, III Playing God? Genetic Determinism and Human Freedom, by Ted Peters Green Space, Green Time: The Way of Science, by Connie Barlow Reconstructing Nature: The Engagement of Science and Religion , by John Brooke and GeoffreyCantor Whatever Happened to the Soul? Scientific and Theological Portraits ofHuman Nature, Edited by Warren S. Brown, Nancey Murphy, and H.Newton Malony The Turn of the Millennium: An Agenda for Christian Religion in an Age of Science, by Jeffrey G. Sobosan God without the Supernatural: A Defense of Scientific Theism, by Peter Forrest Religion and Creation, by Keith Ward     

Diabolic Debates: Replies to Stephen Kent

Steven F. Walker, Jung and the Jungians on Myth: An Introduction. Theorists of Myth Series 4. New York and London: Garland Publishing 1993. xiii+198 pp. $30.00 ISBN 0 8240 3443 0.

Thomas Ryba, The Essence of Phenomenology and its Meaning for the Scientific Study of Religion. New York: Peter Lang 1991. xvii +268 pp. $30.00 ISBN 0 8204 0742 9.     

The legal basis for the Danish committee on scientific dishonesty

The author, a High Court Judge, has chaired the Danish Committee on Scientific Dishonesty (DCSD) since its establishment in 1992. The Committee has worked in the health sector, but from 1999 the scope has been broadened to cover all fields of science. The article describes how the work is organised and the experiences gained. It is stressed, that the difficulty in connection with scientific dishonesty is, first and foremost, to organise a system suitable for investigating cases effectively, professionally, and with proper respect to the fundamental legal rights of the parties involved. The Committee has also spent much effort in determining what can be termed scientific dishonesty and what falls outside this category but which may, nevertheless, be characterised as breaching of good scientific practice. It is emphasised that these rules are not arbitrarily established by the Committee, but formulated in accordance with norms general accepted by opinion leaders in the scientific community. An carlier version of this paper was presented at a symposium, Scientific Misconduct. An International Perspective, organised by The Medical University of Warsaw, 16 November, 1998. The article is based on more comprehensive articles by the same author in DCSD’s Annual Reports for 1993 and 1995.     

Reviews

Book reviews in this article: The Survival of God in the Scientific Age. By Alan Isaacs Faith and the Physical World. By David L. Dye Prophecy in a Technocratic Era. By Arend Theodore van Leeuwen The Living Stream: Evolution and Man. By Alister C. Hardy The Divine Flame: An Essay Towards a Natural History of Religion. By Alister C. Hardy     

Ethical implications in the allocation of scarce medical resources in Poland

The health care system in Poland is undergoing major change and it is possible that these changes could affect clinical research. Therefore, the situation of funding of health care is important for the future of medical research in this country. Some questions relevant in this field will be addressed. Since funds for health care and scientific research remain inadequate, their allocation raises moral, economic, legal and organisational dilemmas. The clinical aspects of resource allocation also include physicians’ responsibilities towards their patients. Scientific research, clinical medicine, and clinical research have a common denominator: they rely on trust. The physician should be a fiduciary of the patient as well as being a researcher for the benefit of the patient and for society. Some physicians and researchers, despite unethical conduct, escape disclosure and punishment, but decision-makers who wrongly allocate funds for health care and research are never held accountable for their actions. An earlier version of this paper was presented at a symposium, Scientific Misconduct: An International Perspective, organised by The Medical University of Warsaw, 16 November, 1998.     

Attaining “a Sophisticated Maturity:” A Brief History of the Journal for the Scientific Study of Religion

An historical overview of the Journal for the Scientific Study of Religion considers both the aspirations of the founders and the extent to which those aspirations have been realized, modified, or exceeded. Appropriate secondary sources are reviewed for an understanding of the intellectual and organizational contexts giving rise to the Journal and for a qualitative consideration of its earliest decades. Then we introduce quantitative data derived from tabulations of all articles and research notes that have appeared in the Journal beginning with its inception in 1961 through 1998. Major trends across time are identified in theories, methods, topics, author characteristics, editor characteristics, and other important traits. The article concludes with evidence of the Journal's premier and significant impact on the social‐scientific study of religion.     

The American experience: Lessons learned

This paper discusses ten lessons learned since 1989 about handling allegations of scientific misconduct involving biomedical and behavioral research supported by the U. S. Public Health Service. An earlier version of this paper was presented at a symposium, Scientific Misconduct: An International Perspective, organised by The Medical University of Warsaw, 16 November, 1998. The opinions expressed herein are those of the author and do not necessarily represent the views of the Office of Research Integrity, the U.S. Department of Health and Human Services, or any other federal agency.     

Principles of good clinical practice (GCP) in clinical research

Good Clinical Practice is an international quality standard for conducting trials that involve participation of human subjects. Currently, the most widely accepted international document forming the base for GCP is the ICH Harmonised Tripartite Guideline for GCP, which defines in detail the responsibilities and obligations of parties engaged in clinical research. The purpose of this paper is to analyse how compliance with GCP provides protection of the trial subjects and assures quality and credibility of the data obtained. An earlier version of this paper was presented at a symposium, Scientific Misconduct: An International Perspective, organised by The Medical University of Warsaw, 16 November, 1998.     

Misconduct in science and the german law

In the past, only norms and rules developed for other types of illegal activities could be applied to misconduct in science in Germany. But only particularly blatant cases of misconduct can be dealt with efficiently in this way. Nowadays, a couple of very important funding agencies and research institutions have enacted special procedures that apply in cases of suspected scientific misconduct. A strongly decentralised system of dealing with misconduct in science is being established in Germany. An earlier version of this paper was presented at a symposium, Scientific Misconduct. An International Perspective, organised by The Medical University of Warsaw, 16 November, 1998.     

Book Reviews

Book reviewed in this article: The Management of Intelligence: Scientific Problem Solving and Creativity by Carl E. Gregory. Creativity: Progress and Potential by Calvin W. Taylor, et al. The Act of Creation by Arthur Koestler. Setting Conditions for Creative Teaching in the Elementary School by James A. Smith. Cognition and Thought: An Information Processing Approach by Walter R. Reitman. Instructional Media and Creativity by Calvin W. Taylor and Frank E. Williams (Eds.). Creative Behavior Guidebook by Sidney J. Parnes.     

Responding to allegations of scientific misconduct

Institutions in France are not yet well prepared to respond to allegations of scientific misconduct. Following a serious allegation in late 1997. INSERM,* the primary organization for medical and health-related research in France, began to reflect on this subject, aided by scientists and jurists. The conclusions have resulted in establishing a procedure to be followed in cases of alleged misconduct, and also in reinforcing the application of good laboratory practices within each laboratory. Guidelines for authorship practices and scientific assessment must also be considered. Even though each institution must remain responsible for responding to allegations of scientific misconduct within its doors, INSERM would like to see national, European, and international co-ordination about the methods of such response. Institut National de la Santé et de la Recherche Médicale (eng. French National Medical Research Institute) is known as INSERM. An earlier version of this paper was presented at a symposium, Scientific Misconduct: An International Perspective, organised by The Medical University of Warsaw, 16 November, 1998.     

Protecting research integrity

It is not contoversial to state that acts of fraud do not belong in the academic world. What is debated is the best way to minimise the risk of fraudulent behaviour. Broadly speaking there are two different approaches to this problem. They differ with regard to whether the main focus is on internal or external control. In this article I argue that the main emphasis should be on internal structures in order to achieve the desired end. Only when the internal structures are in place is it meaningful to adopt external, supportive means to the same end. Invitation to the academic project as such, education and training in research ethics and good research practice, the implementation of good documentation procedures and the implementation of a procedure for investigation of suspicions of fraud which is characterised by efficiency, impartiality and competence are the four primary ingredients in the cure. The first three are suggested to build up the necessary foundation before a structure of investigation procedures are established. An earlier version of this paper was presented at a symposium, Scientific Misconduct: An International Perspective, organised by The Medical University of Warsaw, 16 November, 1998.     

Testing the Domain Specificity of Creativity with Kaufman Domains of Creativity Scale: A Meta-Analytic Confirmatory Factor Analysis

Domain-specificity is a topic of debate within the field of creativity. To shed light on this issue, we conducted a meta-analysis of cross-domain correlations based on the Kaufman Domains of Creativity Scale (K-DOCS). To evaluate the model fit of one general factor versus two factors that encompass the primary K-DOCS subscales (Scholarly, Everyday, Artistic, Scientific, and Performance), we employed the one-stage meta-analytic structural equation modeling (OSMASEM) approach. Poor fit of these models would provide evidence of domain-specificity, as the proposed models would not outperform the independence model. Our analysis included 45 correlation matrices from 30 studies, with a total sample size of 31,136 participants. The results provided support for a general domain of creativity, as well as a two-factor solution consisting of Arts and Sciences factors. Among the subscales, the highest correlation was found between the Artistic and Performance domains (r = .478), while the smallest correlation was observed between the Everyday and Scientific domains (r = .178). Furthermore, moderator analyses incorporating age and gender revealed that the Scientific and Everyday subscales exhibited a stronger factor load in older participants compared to younger participants. Implications are discussed for research and practice.     

Conflict of interest in biomedical research: a view from Europe

In this paper I address the conflict of interest (CoI) issue from a legal point of view at a European level. We will see that the regulatory framework that exists in Europe does state the need for the independence of ethics committee involved in authorisation of research and clinical trials. We will see that CoI is an element that has to be closely monitored at National and International level. Therefore, Member States and Newly Associated States do have to address CoI in the authorisation process of research and clinical protocols of biomedicine. The opinions here expressed are personal and do not commit the European Commission. An earlier version of this paper was delivered at a Conference on Conflict of Interest and Its Significance in Science and Medicine, 5–6 April, 2002, Warsaw, Poland. The author is a Scientific Officer in the Programme Science and Society dealing with ethics and science (Unit C.3).     

Mother,Melancholia, and Dreams in Erik H. Erikson’s <Emphasis Type="Italic">Insight and Responsibility</Emphasis>

In an earlier article (Capps, 2007a) on Erik H. Erikson’s earliest writings (1930–1931) I focused on the relationship between the child’s melancholia and conflict with maternal authority, and drew attention to the restorative role of humor. In a subsequent article (Capps, 2007b) on Erikson’s Childhood and Society (1950) I explored the same theme of the relationship of melancholia and the mother, but focused on the restorative role of play. In this article drawing from his Insight and Responsibility (1964) I continue this exploration of the relationship of melancholia and the mother, but focus on the restorative role of dreams. In support of this understanding of dreams, I focus on Erikson’s interpretation of one of Sigmund Freud’s dreams in light of the first two stages of the life cycle, and his view that the dream itself is inherently maternal. Donald Capps is Professor of Pastoral Psychology at Princeton Theological Seminary. His books include Men, Religion, and Melancholia (1997), Freud and Freudians on Religion (2001), and Men and Their Religion: Honor, Hope, and Humor (2002). He has served as editor of Journal for the Scientific Study of Religion and as President of the Society for the Scientific Study of Religion.     

REALISM WITHOUT TRUTH: A REVIEW OF GIERE'S SCIENCE WITHOUT LAWS AND SCIENTIFIC PERSPECTIVISM

An increasingly popular view among philosophers of science is that of science as action—as the collective activity of scientists working in socially‐coordinated communities. Scientists are seen not as dispassionate pursuers of Truth, but as active participants in a social enterprise, and science is viewed on a continuum with other human activities. When taken to an extreme, the science‐as‐social‐process view can be taken to imply that science is no different from any other human activity, and therefore can make no privileged claims about its knowledge of the world. Such extreme views are normally contrasted with equally extreme views of classical science, as uncovering Universal Truth. In Science Without Laws and Scientific Perspectivism, Giere outlines an approach to understanding science that finds a middle ground between these extremes. He acknowledges that science occurs in a social and historical context, and that scientific models are constructions designed and created to serve human ends. At the same time, however, scientific models correspond to parts of the world in ways that can legitimately be termed objective. Giere's position, perspectival realism, shares important common ground with Skinner's writings on science, some of which are explored in this review. Perhaps most fundamentally, Giere shares with Skinner the view that science itself is amenable to scientific inquiry: scientific principles can and should be brought to bear on the process of science. The two approaches offer different but complementary perspectives on the nature of science, both of which are needed in a comprehensive understanding of science.     

Transcendental idealism among the Jersey metaphysicians

Some questions are posed for van Fraassen, concerning the role and status of metaphysics in his Scientific Representation.     

Promoting research integrity at the American Society for Microbiology

The American Society for Microbiology addresses issues of research integrity in several ways. There is a Code of Ethics for Society members and an Ethics Committee, a Publications Board has editorial oversight of ethical issues involved in Society journals and other publications, and the Public and Scientific Affairs Board is involved in ethical issues and scientific policies at the national level. In addition, the Society uses meetings and publications to inform and educate members about research integrity. An earlier version of this paper was presented at the AAAS-Office of Research Integrity (ORI) meeting in Washington DC on the theme: “The Role and Activities of Scientific Societies in Promoting Research Integrity” held on April 10–11, 2000.     

CLASSI: A classification model for the study of sequential processes and individual differences therein

In psychological research, one often aims at explaining individual differences in S-R profiles, that is, individual differences in the responses (R) with which people react to specific stimuli (S). To this end, researchers often postulate an underlying sequential process, which boils down to the specification of a set of mediating variables (M) and the processes that link these mediating variables to the stimuli and responses under study. Obviously, a crucial task is to chart how the individual differences in the S-R profiles are caused by individual differences in the S-M link and/or by individual differences in the M-R link. In this paper we propose a new model, called CLASSI, which was explicitly designed for this task. In particular, the key principle of CLASSI consists of reducing the S, M, and R nodes of a sequential process to a few mutually exclusive types and inducing an S-M and an M-R person typology from the data, with the S-M person types being characterized in terms of if S type then M type rules and the M-R person types in terms of if M type then R type rules. As such, the S-M and M-R person types and their associated if–then rules represent the important individual differences in the S-M and M-R links of the sequential process under study. An algorithm to fit the CLASSI model is described and evaluated in a simulation study. An application of CLASSI to data from the behavioral domain of anger and sadness is discussed. Finally, we relate CLASSI to other methods and discuss possible extensions. The first author is a post-doctoral fellow of the Fund for Scientific Research—Flanders (Belgium). The research reported in this paper was partially supported by the Research Council of K.U. Leuven (GOA/05/04).