儿童受欺负与急性社会应激中应激反应的关系

研究旨在考察受欺负经历与儿童下丘脑-垂体-肾上腺轴系统应激功能的关系。根据受欺负得分挑选出52名受欺负和未受欺负儿童,考察两类儿童在特里尔社会应激测验(Trier Social Stress Test,TSST)中的皮质醇分泌及主观紧张度的特征差异。结果发现:(1)在TSST中,受欺负者的皮质醇浓度显著高于未受欺负者;(2)两类儿童在TSST中的主观紧张度不存在显著差异。研究结果与慢性应激破坏HPA轴应激功能的过程是从敏化到钝化的理论假说相一致。     

儿童版特里尔社会应激测试对儿童唾液皮质醇、唾液α-淀粉酶和情绪的影响

研究以150名五、六年级的学生为被试,考察儿童版特里尔社会应激测试（TSST-C）对儿童客观生理反应（唾液皮质醇和唾液α-淀粉酶）和主观情绪反应的影响。结果发现,TSST-C引起了儿童显著的应激反应,包括皮质醇和唾液α-淀粉酶水平的升高,以及主观消极情绪（如焦虑和紧张）的增加,这表明TSST-C在中国儿童中的适用情况良好,能够有效诱发儿童的应激反应。同时,研究也发现,皮质醇反应和唾液α-淀粉酶反应不存在相关,生理反应和情绪反应之间也不存在相关。     

特里尔社会应激测试(TSST)对唾液皮质醇分泌的影响

特里尔社会应激测试(Trier Social Stress Test: TSST)是国外应用广泛的社会心理应激测试手段, 然而还没有研究对其在中国的适用性进行报告。本研究以健康大学生为被试, 分别采用主观应激报告(简明心境量表和5点量表)和客观应激参数(心率和唾液皮质醇)为指标, 探讨TSST在中国的适用情况以及性别因素对个体在TSST应激情境中的影响。结果发现, TSST诱发了中国被试显著的应激反应, 在经历了TSST情境后, 被试主观报告紧张水平增加, 同时心跳加速, 唾液皮质醇水平增加。即使女性被试主观报告紧张与不安的程度显著高于男性, 但是男性和女性在TSST应激情境下的心跳和唾液皮质醇指标没有差异。研究结果提示, TSST在中国被试中具有良好的适用性, 可以利用其开展与社会心理应激相关的研究。男女被试在与成就动机相关的应激源(例如, TSST)中的客观应激参数差异不明显。     

自尊与心理性应激的关系初探

自尊水平影响着个体在应激情境中的内分泌反应,在以人个人主义文化下的研究发现,由于低自尊具有较低的内部控制力,因此在应激情境中的唾液皮质醇反应更强烈。但是在中国集体主义文化中,由于集体性自我的评价是自尊的一个重要组成部分,高自尊更加期望集体或社会的积极性评价,因此假设在心理性应激情境下（即个体的能力被否定的时候）,高自尊的应激反应会比低自尊更加强烈。本研究以健康大学生为被试,分别以Rosenberg自尊量表和特里尔社会应激测试（TSST）为实验手段,以自尊量表得分、主观应激报告（5点量表）和客观应激参数（心率和唾液皮质醇）为指标,在中国文化背景下探讨自尊与心理性应激的关系。结果发现,在TSST开始时（20分钟）自尊与心率呈正相关,自尊水平越高,心率越快;在TSST结束后（60分钟）自尊与唾液皮质醇水平呈正相关,自尊水平越高,唾液皮质醇水平越高。总体来说,相对于低自尊被试而言,高自尊被试在心理性应激情境中的反应更为强烈。     

父子依恋、母子依恋与儿童应激下皮质醇反应的关系

本研究以北京115名五、六年级的学生为被试,采用儿童版特里尔社会应激测试(Trier Social Stress Test for Children,TSST-C),探究父子依恋、母子依恋与儿童应激下皮质醇反应的关系。研究分别在基线阶段、TSST-C开始前、TSST-C结束后、TSST-C结束后的10分钟、25分钟和50分钟收集儿童的唾液样本,并让儿童完成亲子依恋问卷。采用SPSS 20.0进行方差分析和回归分析。结果发现:(1)安全型父子依恋儿童的应激下皮质醇反应显著高于不安全型父子依恋儿童,反映在皮质醇值和皮质醇基于增加的曲线下面积(area under the curve with respect to increase,AUCI)两个指标上;(2)不同母子依恋类型儿童的应激下皮质醇反应(即皮质醇值和AUCI)不存在显著差异;(3)在控制了人口学变量之后,父子依恋依旧可以显著地正向预测儿童的皮质醇反应(皮质醇AUCI),但母子依恋对儿童皮质醇反应的预测作用不显著,且父子依恋对儿童皮质醇反应的预测作用边缘显著大于母子依恋对儿童皮质醇反应的预测作用。研究结果表明,安全型父子依恋与儿童应激下更高的皮质醇反应相关。     

不同心理刺激诱发的交感和副交感神经活动的比较

让24名女大学生被试完成划消测验、镜画测验、心算和准备演讲四种应激任务,目的在于探讨在不同心理刺激下交感和副交感神经系统的活动是否存在差异。记录HRV（Heart Rate Variability,心率变异性）的频域成分TP（Total Power,总功率）、HF（High Frequency,高频）、LF（Low Frequency,低频）、LF/HF（低频高频比）、平均R-R间期和血压等指标在基线和不同应激任务期间的变化。通过单因素重复测量方差分析和多重比较发现,准备演讲期间的TP、LF值显著地高于基线和其它三项任务, HF的值显著地高于划消测验和心算;镜画测验、划消测验和心算期间的LF值与基线比较显著下降,TP、LF和HF三项指标在这三项任务之间无显著差异;不同任务期间在LF/HF上无显著主效应。平均R-R间期基线水平与所有任务间的比较及各任务之间有显著差异。收缩压基线水平与划消、镜画任务间的比较有显著差异。结果表明,准备演讲期间的交感神经和副交感神经张力显著地大于其它任务,不同任务表现出的不同的自主神经张力变化说明交感神经与副交感神经活动不是一方活动增强、另一方活动减弱的单纯的活动方式,这一结果为Berntson提出的自主神经活动可能存在九种活动搭配模式的理论提供了实验证据     

社会支持缓解高互依自我个体的急性心理应激反应

高互依自我构念个体以社会角色来定义自己, 更看重自己的社会关系; 社会评价威胁是诱发个体社会心理应激反应的重要情境因素, 然而高互依自我构念个体在心理性应激情境中是否会表现出更高的应激反应, 以及社会支持是否会缓解高互依自我构念个体的急性心理应激反应还不可知。本研究以特里尔社会应激测试为范式, 以主观应激报告、心率和唾液皮质醇作为应激指标, 使用自我构念问卷测量个体互依自我构念水平, 将健康大学生被试随机分配到自我支持启动组和社会支持启动组。结果发现, 互依自我构念水平正向预测个体在应激情境中的皮质醇水平增加量; 同时, 相比于自我支持启动, 高互依自我构念的个体在经历社会支持后有更低的唾液皮质醇变化量。研究结果提示, 社会支持对高互依自我构念个体的急性心理应激反应起到了良好的缓解作用。     

认知抑制对科学创造力和艺术创造力的影响

研究通过2个实验,考察不同高低抑制水平对科学创造力和艺术创造力的影响。通过安排不同难度的Simon任务（不一致试次占70%或10%）来消耗被试的认知资源,达到操纵被试的抑制水平,以侧抑制任务的前后测来评估被试抑制水平的变化情况,实验1和实验2分别以科学创造力测验和粘贴画任务测量被试的科学创造力和艺术创造力。结果发现,在科学创造力测验上,高抑制水平组被试的流畅性和灵活性得分显著高于低抑制水平组;在粘贴画任务中,低抑制水平组被试的创造性、可爱程度、综合印象得分以及总分均显著高于高抑制水平组。表明高认知抑制水平有利于科学创造力,低认知抑制水平有利于艺术创造力,认知抑制对科学创造力和艺术创造力的影响存在分离效应。     

负性事件引发情绪反应的性别特点及神经机制

选取45名大学本科生为被试,记录被试观看内容不同的刺激材料时主观情绪体验成绩,同时采集了心率变异性(HRV)的频域指标,探讨内容不同的负性事件引发情绪反应的性别特点及外周神经机制.结果:在主观报告上,女性所诱发的负性情绪显著高于男性.社会事件的情绪材料所引发的负性情绪显著高于家庭事件的情绪材料.在生理指标上,女性在负性事件中引起的LF/HF显著高于男性.因此,负性事件后男性和女性情绪反应在主观应激强度和生理反应模式上差异显著.     

动态测验对“数学学习困难”儿童的进一步甄别

本研究意在考查动态测验对数学学习困难儿童作进一步程度区分的有效性。以传统且常用的数学学习困难鉴别方式和标准选取30名四年级数学学习困难儿童为实验组,30名同年级智力匹配儿童为对照组,以Swanson认知加工测验(S-CPT)的4个子测验为测量工具对被试进行动态测验。结果发现：(1)在传统数学学习困难鉴别方式的基础上,动态测验的“潜在认知能力”指标可以对儿童数学成绩增加19%的预测力;(2)以“潜在认知能力”指标为依据能够将数学学习困难儿童进一步区分为“发展落后”和“发展缺陷”两个水平;(3)“发展落后”儿童一年内数学成绩发生了增长性变化,与正常儿童水平相当,而“发展缺陷”儿童的数学成绩没有变化。研究证实关注潜能指标的动态测验范式在快速、准确甄别数学学习困难儿童上具有独特效用。     

青少年应激下皮质醇应答与风险决策相关性的性别差异

本研究旨在探讨中国青少年应激下皮质醇应答和风险决策相关性的性别差异。本研究以健康初中生为被试者, 采用特里尔社会应激测试(Trier Social Stress Test, TSST)诱发机体应激反应, 测试唾液皮质醇在应激前后不同时间段的水平, 并要求被试者在应激状态下完成气球模拟风险决策任务(Balloon Analogue Risk Task, BART)。结果发现, 男性在TSST诱导下皮质醇反应度显著高于女性, 男性中高皮质醇应答者BART表现为更高程度的冒险行为和更低的总奖励金额, 而女性中高皮质醇应答者BART表现为更高的总奖励金额。研究结果提示,中国青少年应激条件下皮质醇应答与风险决策之间的联系存在性别差异, 尤其在男性, 高皮质醇应答者更具有冒险行为。     

Timing is everything: Anticipatory stress dynamics among cortisol and blood pressure reactivity and recovery in healthy adults

Psychological states of anticipation modulate biological stress responsivity. While researchers generally investigate how subjective distress corresponds to the magnitude of stress reactivity, physiological recovery after acute stressors must also be considered when investigating disease vulnerabilities. This study assessed whether anticipatory stress would correspond to stress reactivity and recovery of salivary cortisol and blood pressure levels in response to a well-validated psychosocial stressor. Thirty participants (63% female; mean?±?SEM age 45.4?±?2.12 years) were exposed to the Trier Social Stress Test (TSST) consisting of a public speech and mental arithmetic. Ten salivary cortisol samples and systolic and diastolic blood pressure recordings were collected at time points spanning 50?min before and up to 50?min after stress exposure. These data were transformed into parameters representing stress reactivity (area under the curve) and stress recovery (percent change). The Primary Appraisal Secondary Appraisal scale assessed anticipatory stress before exposure to the TSST. Our results revealed that increased anticipatory stress predicted increased stress reactivity for cortisol (p?=?0.009) but not blood pressure. For stress recovery, increased anticipatory stress predicted greater decrements of cortisol concentration (p?=?0.015) and blood pressure (p?=?0.039), even when controlling for total systemic "output" by incorporating baseline activity. This efficient shutdown of stress responses would have otherwise been ignored by solely investigating reactive increases. These findings underscore the importance of measuring multiple dynamic parameters such as recovery when investigating physiological stress response patterns as a function of psychosocial factors.     

Acute psycho-social stress does not disrupt item-method directed forgetting, emotional stimulus content does

It has been shown that stress affects episodic memory in general, but knowledge about stress effects on memory control processes such as directed forgetting is sparse. Whereas in previous studies item-method directed forgetting was found to be altered in post-traumatic stress disorder patients and abolished for highly arousing negative pictorial stimuli in students, no study so far has investigated the effects of experimentally induced psycho-social stress on this task or examined the role of positive picture stimuli. In the present study, 41 participants performed an item-method directed forgetting experiment while being exposed either to a psychosocial laboratory stressor, the Trier Social Stress Test (TSST), or a cognitively challenging but non-stressful control condition. Neutral and positive pictures were presented as stimuli. As predicted, salivary cortisol level as a biological marker of the human stress response increased only in the TSST group. Still, both groups showed directed forgetting. However, emotional content of the employed stimuli affected memory control: Directed forgetting was intact for neutral pictures whereas it was attenuated for positive ones. This attenuation was primarily due to selective rehearsal improving discrimination accuracy for neutral, but not positive, to-be-remembered items. Results suggest that acute experimentally induced stress does not alter item-method directed forgetting while emotional stimulus content does.     

Parent support is less effective in buffering cortisol stress reactivity for adolescents compared to children

The goal of the present study was to investigate developmental differences in the effectiveness of parent support to alleviate hypothalamic‐pituitary‐adrenal (HPA) axis stress responses of children (ages 9–10, N = 40) and adolescents (ages 15–16, N = 41). We experimentally manipulated the provision of parent support during the speech preparation period before a modified Trier Social Stress Test (TSST) and examined its effect on levels of salivary cortisol secreted in response to this laboratory stressor. Analyses revealed a significant interaction of condition and age group such that social support from the parent (versus a stranger) significantly eliminated the cortisol stress response in children, but had no effect on the response among adolescents.     

自尊与心理性应激反应的关系：社会认可需求的中介作用

国外研究者认为高自尊个体的内控性高,因此其在心理性应激情境中的反应不那么强烈,而国内研究者从集体文化(中国)考虑,则认为高自尊个体的社会认可需求较高,因此在心理性应激情境中的反应更强烈.本研究采用特里尔社会应激测试作为应激情境,采集41名中国大学生被试在这一情境下的客观参数(心率)作为心理性应激反应的指标,通过问卷测量被试的自尊水平、内控性水平和社会认可需求水平,考察自尊影响心理性应激反应的机制.结果发现被试的自尊水平与应激情境下的心率呈正相关,并且社会认可需求在自尊与心理性应激的关系中起着显著的中介作用.本文从文化差异角度提出自尊预测心理性应激反应的模型可能需要在不同文化背景下来分别探讨.     

Stress impairs acquisition of delay eyeblink conditioning in men and women

In rodents stress impairs delay as well as trace eyelid conditioning in females, but enhances it in males. The present study tested the effects of acute psychosocial stress exposure on classical delay eyeblink conditioning in healthy men and women. In a between subject design, participants were exposed to psychosocial stress using the Trier Social Stress Test (TSST) or a control condition which was followed by a delay eyeblink classical conditioning procedure. Stress exposure led to a significant increase in salivary cortisol and impaired acquisition of conditioned eyeblink responses (CRs). This was evident by a later first CR and an overall lower CR rate of the stress group. The stress-induced acquisition impairment was observed in both women and men. Subjects failing to show a stress-induced cortisol increase (cortisol non-responder) were not impaired in acquisition. Our findings indicate that acute stress, possibly via activation of the hypothalamus–pituitary–adrenal (HPA) axis, reduces the ability to acquire a simple conditioned motor response in humans.