Putative sex differences in verbal abilities and language cortex: a critical review

This review brings together evidence from a diverse field of methods for investigating sex differences in language processing. Differences are found in certain language-related deficits, such as stuttering, dyslexia, autism and schizophrenia. Common to these is that language problems may follow from, rather than cause the deficit. Large studies have been conducted on sex differences in verbal abilities within the normal population, and a careful reading of the results suggests that differences in language proficiency do not exist. Early differences in language acquisition show a slight advantage for girls, but this gradually disappears. A difference in language lateralization of brain structure and function in adults has also been suggested, perhaps following size differences in the corpus callosum. Neither of these claims is substantiated by evidence. In addition, overall results from studies on regional grey matter distribution using voxel-based morphometry, indicate no consistent differences between males and females in language-related cortical regions. Language function in Wada tests, aphasia, and in normal ageing also fails to show sex differentiation.     

Neural evidence for the interplay between language, gesture, and action: a review

Co-speech gestures embody a form of manual action that is tightly coupled to the language system. As such, the co-occurrence of speech and co-speech gestures is an excellent example of the interplay between language and action. There are, however, other ways in which language and action can be thought of as closely related. In this paper we will give an overview of studies in cognitive neuroscience that examine the neural underpinnings of links between language and action. Topics include neurocognitive studies of motor representations of speech sounds, action-related language, sign language and co-speech gestures. It will be concluded that there is strong evidence on the interaction between speech and gestures in the brain. This interaction however shares general properties with other domains in which there is interplay between language and action.     

Cognitive and Behavioral Treatments for Anxiety and Depression in a Patient with an Implantable Cardioverter Defibrillator (ICD): A Case Report and Clinical Discussion

Implantable cardioverter-defibrillators (ICDs) are the treatment of choice for patients at risk for potentially life threatening arrhythmias. The associated stress of living with an implanted device and receiving ICD shock therapy has been noted to exert a psychological toll on the individual patient and family. Anxious and depressive symptomatology is frequently reported by these patients, thus creating a demand for tailored psychological interventions for this population. The current case report describes the components, delivery, and effectiveness of a targeted treatment approach for anxiety and depression in an individual with an ICD. Test results and interview data revealed significant improvements in multiple domains of cognitive, emotional, and behavioral functioning. Improvements in marital relations were also achieved. These treatment effects were maintained at follow-up and in the context of acute, medical stressors. Future clinical and research directions are also discussed.     

Synchrnoic consciousness from a neurological point of view: the philosophical foundations for neuroethics

Daniel Kolak’s theory of synchronic consciousness according to which the entire range of dissociative phenomena, from pathologies such as MPD and schizophrenia to normal dream states, are best explained in terms of consciousness becoming simultaneously identified as many selves, has revolutionary therapeutic implications for neurology and psychiatry. All these selves, according to Kolak—even the purely imaginary ones that exist as such only in our dreams—are not just conscious but also self-conscious, with beliefs, intentions, living lives informed by memories (confabulatory, in the case of the fictional ones) and personal histories. Kolak’s derivation of psychiatrically relevant aspects of his theory—a neurological rendition of a Kantian transcendental argument—can be given a straightforward neurological, and therefore open to scientific scrutiny, interpretation that would then more easily lend itself to the clinical setting in which these perplexing phenomena, along with their purveyors, must live and cope. This will be the main focus of this paper.     

Treating a Chronically Depressed Adolescent Female Using the Cognitive Behavioral Analysis System of Psychotherapy: A Case Study

A case is presented of an adolescent female with double depression who was treated using the Cognitive Behavioral Analysis System of Psychotherapy (CBASP). CBASP is designed to teach a social problem-solving procedure called Situational Analysis (SA). Generalized treatment effects were measured through monitoring of diagnostic status, two administrations of the Minnesota Multiphasic Personality Inventory-Adolescent, weekly administrations of the Child Depression Inventory, and acquisition performance ratings on the SA task. The results showed that CBASP appeared to be an effective treatment. The double depressive disorder remitted, and the patient learned to identify behavioral consequences as well as target and attain her interpersonal goals. CBASP can be effective for adolescents, although modifications of the adult form of the therapy may be necessary.     

Interplay between acoustic/phonetic and semantic processes during spoken sentence comprehension: an ERP study

When listening to speech in everyday-life situations, our cognitive system must often cope with signal instabilities such as sudden breaks, mispronunciations, interfering noises or reverberations potentially causing disruptions at the acoustic/phonetic interface and preventing efficient lexical access and semantic integration. The physiological mechanisms allowing listeners to react instantaneously to such fast and unexpected perturbations in order to maintain intelligibility of the delivered message are still partly unknown. The present electroencephalography (EEG) study aimed at investigating the cortical responses to real-time detection of a sudden acoustic/phonetic change occurring in connected speech and how these mechanisms interfere with semantic integration. Participants listened to sentences in which final words could contain signal reversals along the temporal dimension (time-reversed speech) of varying durations and could have either a low- or high-cloze probability within sentence context. Results revealed that early detection of the acoustic/phonetic change elicited a fronto-central negativity shortly after the onset of the manipulation that matched the spatio-temporal features of the Mismatch Negativity (MMN) recorded in the same participants during an oddball paradigm. Time reversal also affected late event-related potentials (ERPs) reflecting semantic expectancies (N400) differently when words were predictable or not from the sentence context. These findings are discussed in the context of brain signatures to transient acoustic/phonetic variations in speech. They contribute to a better understanding of natural speech comprehension as they show that acoustic/phonetic information and semantic knowledge strongly interact under adverse conditions.     

Learning to control brain activity: a review of the production and control of EEG components for driving brain-computer interface (BCI) systems

Brain-computer interface (BCI) technology relies on the ability of individuals to voluntarily and reliably produce changes in their electroencephalographic (EEG) activity. The present paper reviews research on cognitive tasks and other methods of generating and controlling specific changes in EEG activity that can be used to drive BCI systems. To date, motor imagery has been the most commonly used task. This paper explores the possibility that other cognitive tasks, including those used in imaging studies, may prove to be more effective. Other factors which influence performance are also considered in relation to selection of tasks, as well as training of subjects.     

Acute stress disorder among civilians during a war and post-traumatic growth six years later: the impact of personal and social resources

Background and Objectives: Various studies suggest a link between stress response to a traumatic event and post-traumatic growth (PTG), but little is known about their long-term relationship. In this study, the relationship between acute stress disorder (ASD) among civilians during a war on the home front and PTG six years later was examined for the first time. Based on the conservation of resources (COR) theory, the role of personal and social resource loss and gain as moderating factors was investigated. Design and Methods: At Time 1 of the research (the Second Lebanon War in 2006), a structured questionnaire was administered to 370 civilians living within rocket range. At Time 2, 6 years later, 301 participants from Time 1 were again examined. The data analysis refers to the 301 respondents who participated at Time 2. Results: The findings indicate a significant relationship between ASD and PTG. Examination of the interaction revealed that resource gain (but not resource loss) moderates (strengthens) the relationship between the two. Conclusions: These findings are not consistent with the COR view that resource loss has a greater effect on stress responses than resource gain.     

The effects of music exposure and own genre preference on conscious and unconscious cognitive processes: a pilot ERP study

Did Beethoven and Mozart have more in common with each other than Clapton and Hendrix? The current research demonstrated the widely reported Mozart Effect as only partly significant. Event-related brain potentials (ERPs) were recorded from 16 professional classical and rock musicians during a standard 2 stimulus visual oddball task, while listening to classical and rock music. During the oddball task participants were required to discriminate between an infrequent target stimulus randomly embedded in a train of repetitive background or standard stimuli. Consistent with previous research, the P3 and N2 ERPs were elicited in response to the infrequent target stimuli. Own genre preference resulted in a reduction in amplitude of the P3 for classical musicians exposed to classical music and rock musicians exposed to rock music. Notably, at the pre-attentive stage of processing (N2) beneficial effects of exposure to classical music were observed for both groups of musicians. These data are discussed in terms of short and long-term music benefits on both conscious and unconscious cognitive processes.     

Cognitive control of language production in bilinguals involves a partly independent process within the domain-general cognitive control network: evidence from task-switching and electrical brain activity

In highly proficient, early bilinguals, behavioural studies of the cost of switching language or task suggest qualitative differences between language control and domain-general cognitive control. By contrast, several neuroimaging studies have shown an overlap of the brain areas involved in language control and domain-general cognitive control. The current study measured both behavioural responses and event-related potentials (ERPs) from bilinguals who performed picture naming in single- or mixed-language contexts, as well as an alphanumeric categorisation task in single- or mixed-task context. Analysis of switch costs during the mixed-context conditions showed qualitative differences between language control and domain-general cognitive control. A 2 × 2 ANOVA of the ERPs, with domain (linguistic, alphanumeric) and context (single, mixed) as within-participant factors, revealed a significant interaction, which also suggests a partly independent language-control mechanism. Source estimations revealed the neural basis of this mechanism to be in bilateral frontal-temporal areas.