动态面孔和语音情绪信息的整合加工及神经生理机制

面孔、语音情绪信息的整合加工是社会交往的重要技能, 近年来逐渐引起心理学、神经科学研究的关注。当前研究较为系统地考察了双通道情绪信息整合加工的行为表现和影响因素, 也很好地回答了“何时整合”与“在哪里整合”两个认知神经科学关注的问题, 但对“面孔、语音情绪信息能否整合为一致情绪客体？双通道情绪信息在大脑中如何整合为一？”两个关键问题都还缺乏系统研究。因此, 本项目拟系统操纵面孔、语音刺激的情绪凸显度和任务要求, 引入动态面孔-语音刺激以增加外部效度, 综合运用行为和电生理技术, 从多角度挖掘数据, 特别是引入神经振荡(时频、相干)分析, 系统考察动态性面孔和语音情绪信息是否能整合成一致情绪客体, 并在神经振荡层面探明双通道情绪信息整合的机制。     

创造力产生过程中的神经振荡机制

创造力究竟是怎么产生的, 目前尚未得出一致的结论。神经电生理技术因其高时间分辨率, 可以准确地揭示创造力产生进程中的神经振荡机制, 从而帮助人们更深刻地理解创造力的本质。近年来的研究发现, 单节律alpha神经振荡会随着创造力的增加而增强, 这反映了创造力产生过程中的内部信息加工需求增加、自上而下的抑制控制增强。同时, 多频段神经振荡交叉节律耦合体现了创造性产生过程中额叶、颞叶和顶叶等多脑区之间信息交流的动态变化。未来研究应该以整合理论框架为基础, 结合多层次多方法的研究工具, 引进更生态化的数理计算方法, 并利用计算神经科学建模来预测个体创造力发展趋势, 从而全面深刻地认识创造力的本质。     

面孔表情和声音情绪信息整合加工的脑机制

在现实生活中, 有效的情绪识别往往依赖于不同通道间的信息整合(如, 面孔、声音)。本文梳理相关研究认为, 面孔表情和声音情绪信息在早期知觉阶段即产生交互作用, 且初级感知觉皮层负责两者信息的编码; 而在晚期决策阶段, 杏仁核、颞叶等高级脑区完成对情绪信息内容的认知评估整合; 此外, 神经振荡活动在多个频段上的功能耦合促进了跨通道情绪信息整合。未来研究需要进一步探究两者整合是否与情绪冲突有关, 以及不一致的情绪信息在整合中是否有优势, 探明不同频段的神经振荡如何促进面孔表情和声音情绪信息整合, 以便更深入地了解面孔表情和声音情绪信息整合的神经动力学基础。     

工作记忆的神经振荡调控：基于神经振荡夹带现象

工作记忆的神经振荡机制研究是当前记忆领域的研究热点之一。那么, 神经振荡仅仅是工作记忆过程的伴随现象, 还是直接参与并调控了工作记忆的加工过程?已有研究发现, 大脑内部的神经振荡活动在外界节律性刺激的驱动下, 逐步与外界刺激节律相位同步化, 这一现象被称为“神经振荡夹带”。重复经颅磁刺激(repetitive Transcranial Magnetic Stimulation, rTMS)和经颅交流电刺激(transcranial Alternating Current Stimulation, tACS)干预研究基于此现象, 对大脑局部脑区施加节律性磁、电刺激, 进而调控工作记忆过程中特定频段的神经振荡活动、跨频段的神经振荡耦合或跨脑区的神经振荡相位同步, 为神经振荡参与工作记忆加工提供较为直接的因果证据。未来研究需考虑从脑网络的角度出发, 调控多个脑区之间的神经振荡活动, 进一步考察神经振荡对工作记忆的影响。此外, 还需注意探索和优化rTMS/tACS调控工作记忆的刺激方案, 并辅以客观的脑电记录, 提高该类研究的有效性和可重复性, 最终达到提高工作记忆能力的目的。     

视听跨通道信息的整合与冲突控制

多通道信息交互是指来自某个感觉通道的信息与另一感觉通道的信息相互作用、相互影响的一系列加工过程。主要包括两个方面：一是不同感觉通道的输入如何整合;二是跨通道信息的冲突控制。本文综述了视听跨通道信息整合与冲突控制的行为心理机制和神经机制,探讨了注意对视听信息整合与冲突控制的影响。未来需探究视听跨通道信息加工的脑网络机制,考察特殊群体的跨通道整合和冲突控制以帮助揭示其认知和社会功能障碍的机制。     

γ节律神经振荡：反映自闭症多感觉整合失调的一项重要生物指标

多感觉整合是对不同感官信息进行选择、联系、统一乃至解释的加工过程, 它需要神经系统不同功能区域的共同投入与相互协调, 以实现多种感觉信息的时间捆绑以及全局性的预测编码。而γ神经振荡因具有反映神经皮层兴奋/抑制的平衡状况, 实现多感官信息的时间同步, 以及通过跨频耦合实现全局性预测编码的特点, 在多感觉整合的加工过程中发挥着重要作用。相比正常个体, 自闭症患者神经系统中的GABA中间神经元存在结构与功能异常, 导致γ神经振荡紊乱, 由此破坏了正常的时间同步以及预测编码加工, 并最终引发多感觉整合失调。基于上述因果关联, 未来研究可结合无创可逆性干预技术, 以γ节律神经振荡为生物反馈指标, 形成科学系统化的临床干预治疗方案。     

自我信息的反应抑制优势：来自神经振荡的证据

为探明个体对自我信息的反应抑制神经机制,记录了被试在完成面孔识别的停止信号任务时的脑电信号。神经振荡结果显示,反应任务中,加工自我面孔引发了更大的同步化δ节律和去同步化β节律;停止任务中,自我面孔引发了更大的去同步化β节律,特别在大脑前额区和中线上。表明,自我信息的反应抑制优势发生在抑制控制阶段,在于增强的β节律的去同步化促进了运动准备,提高了后续的动作抑制的速度。     

厌恶加工的神经基础

厌恶是由令人不愉悦、反感的事物诱发的情绪。根据刺激类型的不同, 厌恶可以分为不同的类型。脑岛和基底节是厌恶加工的主要脑区, 前扣带回、杏仁核、丘脑、内侧前额叶也参与厌恶加工。对已有研究的总结发现, 不同类型的厌恶、不同感觉通道的厌恶加工可能具有不同的神经基础。在未来的研究中, 应当注重研究厌恶加工的认知机制、神经基础以及与厌恶相关的神经递质等问题。     

前额叶神经振荡活动反映了稳固的刺激冲突和反应冲突

为考察典型Flanker任务中练习对刺激冲突和反应冲突的影响,本研究采用练习范式记录被试完成2:1字母Flanker任务时的行为和脑电数据。行为结果发现,练习对这两类冲突无显著影响。神经震荡能量结果发现,前额叶theta能量随练习而显著减弱,这暗示刺激-反应之间的联结因练习而提升;前额叶alpha能量差异不随练习而变化,这可能反映了Flanker任务中稳定的刺激冲突和反应冲突加工机制。因此,本研究揭示了典型Flanker任务中刺激冲突和反应冲突的稳定特征。     

神经振荡：窥探句法解析的时间进程

在语言表型与神经机制之间寻找对应关系,即所谓的映射问题(the mapping problem),是当前研究的一大热点。其中,句法解析的神经机制尤具挑战性,这涉及到如何在神经活动中识别出对应于句法结构构建的过程,是人类语言能力之谜破题的关键。近期神经振荡活动的相关研究不仅为句法解析过程中句法加工的心理现实性提供了有力证据,也展示了利用神经振荡来阐释句法解析过程的神经编码活动的可行性。而理论语言学最简方案有关句法计算的理论模型可以与神经科学中有关神经振荡的实验研究相互印证,通过此类研究可以窥探句法构建的时间进程。未来研究可集中于四方面：神经振荡与句法加工的更细粒度对齐;神经振荡的发生机制及其生物学意义;儿童语言发展过程中神经振荡的变化模式;语言障碍神经生理基础及其康复应用。     

视-听跨通道汉语词汇信息加工中的抑制机制

采用选择性再认的方法考察在汉语词汇加工过程中 ,视 -听跨通道信息与视觉单通道信息加工过程中的抑制机制。结果表明 :对于视觉词汇的总体再认“否”反应 ,单通道干扰条件下的成绩优于跨通道干扰条件下的成绩。在视觉词汇加工过程中 ,对外在干扰材料的抑制效率不受输入干扰刺激的通道的影响。抑制效率受干扰材料语义关系性的影响 ,与目标材料属于同一语义范畴的比异范畴的干扰材料更难以被抑制。     

Cross-modal working memory binding and word recognition skills: how specific is the link?

Recent research has suggested that the creation of temporary bound representations of information from different sources within working memory uniquely relates to word recognition abilities in school-age children. However, it is unclear to what extent this link is attributable specifically to the binding ability for cross-modal information. This study examined the performance of Grade 3 (8–9 years old) children on binding tasks requiring either temporary association formation of two visual items (i.e., within-modal binding) or pairs of visually presented abstract shapes and auditorily presented nonwords (i.e., cross-modal binding). Children’s word recognition skills were related to performance on the cross-modal binding task but not on the within-modal binding task. Further regression models showed that cross-modal binding memory was a significant predictor of word recognition when memory for its constituent elements, general abilities, and crucially, within-modal binding memory were taken into account. These findings may suggest a specific link between the ability to bind information across modalities within working memory and word recognition skills.     

Sub-centimeter language organization in the human temporal lobe

The human temporal lobe is well known to be critical for language comprehension. Previous physiological research has focused mainly on non-invasive neuroimaging and electrophysiological techniques with each approach requiring averaging across many trials and subjects. The results of these studies have implicated extended anatomical regions in peri-sylvian cortex in speech perception. These non-invasive studies typically report a spatially homogenous functional pattern of activity across several centimeters of cortex. We examined the spatiotemporal dynamics of word processing using electrophysiological signals acquired from high-density electrode arrays (4 mm spacing) placed directly on the human temporal lobe. Electrocorticographic (ECoG) activity revealed a rich mosaic of language activity, which was functionally distinct at four mm separation. Cortical sites responding specifically to word and not phoneme stimuli were surrounded by sites that responded to both words and phonemes. Other sub-regions of the temporal lobe responded robustly to self-produced speech and minimally to external stimuli while surrounding sites at 4 mm distance exhibited an inverse pattern of activation. These data provide evidence for temporal lobe specificity to words as well as self-produced speech. Furthermore, the results provide evidence that cortical processing in the temporal lobe is not spatially homogenous over centimeters of cortex. Rather, language processing is supported by independent and spatially distinct functional sub-regions of cortex at a resolution of at least 4 mm.     

梦中脑内信息加工的讨论

用信息加工的观点讨论梦中脑内信息加工的特点 ,认为梦中脑内信息加工多数是浅的自动加工 ,既有串行加工又有并行加工 ,而进入梦境的信息是串行加工的。     

信息加工阶段独立资源的新证据

本研究对与加工阶段有关的独立资源问题进行了研究。实验采用双任务测定方法 ,分别设计了模拟追踪、记忆搜寻和模拟监控等三种主作业 ,以及简单反应时、复杂反应时和手指节奏敲击等三种次作业。这些作业分别动用了与三维度资源理论加工阶段维度的视觉编码、中枢加工和运动输出相对应的三类独立资源。将这六种作业进行匹配 ,共组合成 3× 3种双任务作业情境。实验以次作业绩效为分析指标。结果发现 ,以往对信息加工独立资源的分类过于粗略。另外 ,研究还发现 ,除独立资源外 ,还存在某些通用资源。     

A new look at the syntax-discourse interface: the use of binding principles in sentence processing

Within Generative Grammar, binding constraints on co-reference are usually defined in syntactic terms. However, some researchers have pointed out examples in which syntactically defined binding constraints do not seem to apply, proposing instead that a complete account of linguistic co-reference needs to consider notions of discourse structure. There have been several proposals in the literature for the division of labor between syntax and discourse in the definition of binding constraints. In this paper, we review these proposals in the context of recent work that applies on-line techniques to explore the roles of syntactic and discourse preferences in terms of the time course with which they become active during sentence comprehension. Some of this research suggests that (syntactic) binding principles may be momentarily applied during processing, even in cases in which the final interpretation suggests otherwise. We end the paper by considering the theoretical and methodological implications of this view.     

Spatial co-location and infants'' learning of auditory-visual associations

The role of spatial co-location between sight and sound in infants' cross-modal learning was examined in three experiments. Four-and 6-month-old infants were familiarized with a toy and an accompanying soundtrack. Across conditions, spatial congruity between sight and sound was varied. Following familiarization, infants were tested to determine under which conditions they learned to associate the toy with the sound. Results indicated age-related differences in how discrepant in location a sight and sound could be for infants to form a cross-modal association based on the amodal invariant of co-location. Specifically, 4-month-olds formed cross-modal associations under conditions of less precise co-location than did 6-month-olds. Parallel improvements in infants' sound localization abilities across this age span are likely a contributing factor to the observed developmental trend in cross-modal learning.