关于异种器官移植的问题

随着器官移植的广泛开展,器官短缺的问题日渐突出,８０年代末起异种器官移植的应用引起人们的重视,并形成热潮。但研究表明,克服异种移植排斥非易事,异种器官移植可能引起的病毒性疾病的传播,以及异种器官分子不相容性造成的种属屏障,都使异种器官移植的前景难料。     

国外有关异种移植与伦理学的讨论

今天,医学界的许多问题已经在公众调查方面很公开了。异种移植在成为一种临床治疗手段后,势必也将带来激烈的讨论。国外有关这一方面的讨论较多,主要集中在以下几个方面。在60年代早期,外科医生尝试了用黑猩猩和狒狒的肾、心及肝进行异种移植,早期的研究工作多集中在异种移植的技术可行性及操作过程。在当时,有关异种移植的伦理学问题尚未提出。1984年,在Ｂａｉｌｅｙ及其同事完成了一例狒狒心脏移植到一新生儿体内后,伦理学的问题如“一石激起千层浪”,顿时在美国医学界引起争论。在那时,由于缺少供体,所以在器官短缺的前提下,有关伦理学的…     

异种器官移植及其伦理问题

目前,开展的异种移植研究主要以猪为供体源,面临的主要障碍是宿主抗移植物的免疫排斥反应(超急性排斥、急性排斥和慢性排斥)和猪内源性反转录病毒感染,并已取得一定进展.但异种移植引发的伦理问题也不容忽视,主要有跨物种感染、卫生资源分配、动物的权利和人格同一性等问题.     

异种器官移植研究中的生命伦理学思考

异种器官移植作为解决移植器官严重短缺问题的潜在途径,引发了诸多争论和关注,因而提出运用生命伦理学的原则,重新认识和评价异种器官移植,旨在对其研究进行规范.     

关于异种移植研究的争论

异种移植一方面能为得不到同种供体器官的病人带来生的希望,另一方面又存在着给整个人类带来毁灭性疫病流行的潜在风险。因此,对异种移植研究一直存在许多争论。总结不同学者之间关于跨物种感染、合适的研究准尉等方面的争论,对比不同国家公众的态度,并进一步分析其中隐含的问题,具有十分重要的意义。     

器官移植伦理

正将具有活力的人体器官、组织或细胞用手术或其他方法移植于自体或他体所应遵循的伦理规范,亦称脏器移植伦理,是生命伦理学的分支。根据供者和受者遗传基因的差异,器官移植可分类为自体移植、同质移植、同种移植和异种移植。器官移植伦理是器官移植技术与社会文化、伦理观念的凝结,它以生命伦理的原则     

裸鼠肿瘤模型建立及应用中的几种辩证关系

裸鼠肿瘤模型建立及应用中的几种辩证关系北京医科大学人民医院（１０００３４）李文锦,吕文英人类肿瘤异种移植已有近百年的历史,然而只是在１９６９年Ｒｙｇａａｒｄ首次报道人癌在裸鼠上移植成功后,［１］肿瘤移植才有了突飞猛进的发展。由于遗传突变的先天性免疫缺...     

异种移植的伦理法律问题探析

从异种器官移植发展的现状和有利条件出发,分析社会各界在异种器官移植问题上形成的人体器官范围如何界定、安全性、社会伦理、动物权利保护等几大争论焦点;积极借鉴国外在异种器官移植方面关于安全性规范、动物权利保护等问题上先进的法律制度。最后,提出进一步发展我国异种器官移植的建议,一方面,要完善我国异种器官移植安全性法律规范,成立专门机构并健全器官准入制度和监督机制;另一方面,要明确相关的违约、侵权法律责任。     

异种移植技术的伦理问题研究综述

荷马史诗<奥德赛>中女巫瑟茜(Circe)给奥德修斯(Odysseus)手下的人喝了一种奶酪、蜂蜜和葡萄酒的混合物,他们长出了猪的脑袋和猪鬃.这里包含人类早期对异种移植的幻想.     

应用烧伤整形外科技术治疗大面积皮肤撕脱伤

探讨大面积皮肤撕脱伤的治疗方法。分析总结大面积皮肤撕脱伤及合并损伤17例,根据伤情综合应用清创撕脱皮肤缝合、带蒂真皮下血管网皮瓣回植、撕脱皮肤反取皮回植、组织瓣转移修复、游离皮片移植、头皮取皮术、异体／异种皮移植、创面持续负压吸引VSD等治疗方法,观察创面修复、肢体外观及功能恢复情况。结果17例患者经综合治疗后创面均愈合。功能部位均予全层皮片或皮瓣修复;19处创面有深部组织外露,予皮瓣或肌瓣修复;随访6个月～3年,所有肢体功能良好。根据皮肤软组织损伤情况而综合运用多种烧伤整形外科技术修复大面积撕脱伤可缩短疗程,并最大可能保留受伤区域的功能与外观,改善患者生活质量。     

中国本土化心理治疗的回顾与思考

心理治疗的理论建构、价值取向和具体操作,受到社会文化的深刻影响,而现代的心理治疗理论及操作技术多产生于西方,所以应该研究创立中国本土化的心理治疗理论及操作技术.通过对中国古代传统心理治疗和现代西方心理治疗中国化的回顾,分析中国文化和哲学对本土心理治疗的影响,探讨发展中国本土化心理治疗的途径.     

Animal spare parts? A Canadian public consultation on xenotransplantation

Xenotransplantation, or the use of animal cells, tissues and organs for humans, has been promoted as an important solution to the worldwide shortage of organs. While scientific studies continue to be done to address problems of rejection and the possibility of animal-to-human virus transfer, socio-ethical and legal questions have also been raised around informed consent, life-long monitoring, animal welfare and animal rights, and appropriate regulatory practices. Many calls have also been made to consult publics before policy decisions are made. This paper describes the Canadian public consultation process on xenotransplantation carried out by the Canadian Public Health Association in an arm’s length process from Health Canada, the ministry overseeing government health policy and regulation. Focusing on six citizen fora conducted around the country patterned after the citizen jury deliberative approach, the paper describes the citizen panelists’ recommendations to hold off on proceeding with clinical trials and the rationales behind this recommendation. The consultation process is discussed in the context of constructive technology assessment, a framework which argues for broader input into earlier stages of technology innovation, particularly at the technology design stage. This study was supported by a grant to the first author from the Social Sciences and Humanities Research Council in Canada.     

正确理解知情同意

知情同意最初由美国于18世纪末19世纪初提出,随着社会不断进步,医学科学的不断发展,人们权力意识的不断增强,知情同意作为患者享有的一项权力,医务人员在医疗过程中应遵循的一条原则已日益到人们的关注。然而在现实的医疗实践中人们对这一的理解和认识还存在一定的偏差。正确理解,践行知情同意既是尊重患者的权利,贯彻“以病人为中心”的原则的保证,也能有效地保护医务人员的合法权益。     

世界和谐:全球治理中国际组织的伦理诉求

世界和平与发展需要和谐的国际社会环境,世界和谐是构建性的。以世界和谐为伦理诉求的国际组织在全球治理中发挥着重要的作用,并遵循公正与共生的伦理原则。同时,在实践中正确处理有关主权、人权、国际责任、人道主义等方面的问题,才能真正实现世界和谐。     

The metaphysical basis of a liberal organ procurement policy

There remains a need to properly analyze the metaphysical assumptions underlying two organ procurement policies: presumed consent and organ sales. Our contention is that if one correctly understands the metaphysics of both the human body and material property, then it will turn out that while organ sales are illiberal, presumed consent is not. What we mean by illiberal includes violating rights of bodily integrity, property, or autonomy, as well as arguing for or against a policy in a manner that runs afoul of Rawlsian public reason.     

The Global Reach of Human Rights

We live in a world in which the idea of human rights is persistently invoked. However, despite the tremendous appeal of the idea of human rights, it is also seen by many as lacking in foundation. I have argued, particularly in my book The Idea of Justice, that human rights are best seen as articulations of commitments in social ethics, comparable to — but very different from — accepting utilitarian reasoning. Like other ethical tenets, human rights can, of course, be disputed, but the claim is that they will survive open and informed scrutiny. This view contrasts with seeing human rights in primarily legal terms, either as consequences of humane legislation, or as precursors of legal rights, or as pointing towards what should ideally be legal rights. Human rights may well be reflected in legislation, may inspire legislation, and may even serve, in many circumstances, as ideals that demand legislative attention. However, these are ‘further facts’— not the defining characteristics of human rights.     

Corporations,Rights, and Lobbying

While there may be several practical concerns regarding the practice of corporate lobbying of government officials, there is the more basic question of a corporation’s moral right to do so. I argue that group agents such as corporations have no moral rights, and thereby cannot have the right to lobby. There may be a basis for some legal rights for corporations, but I argue that lobbying cannot be one of the legal rights, even by reference to the rights of the individuals that make up the corporation. I end the paper by a discussion of how this argument applies to all private organizations, including public interest organizations.     

幼儿对所有权权利的理解

对物品的所有权意味着所有者对所有物具有多重权利, 如触碰、使用、更改、追踪和转移等。研究发现, 3岁幼儿就能理解, 所有者对自己的物品具有触碰权和使用权, 而他人不具有。但是, 他们理解所有物的更改权、追踪权和转移权, 却相对滞后。这提示对不同所有权权利表征的发展可能是分化的。此外, 3岁幼儿还理解所有者具有赋予他人使用所有物的权利, 还会积极维护这种权利, 并对阻止权利实施的行为表示抗议, 说明他们也能理解二级所有权权利。为什么幼儿对不同所有权权利的表征会出现分化, 其背后的机制需要未来研究的探索。此外, 某些公共物品(如公共汽车)本身存在着所有权权利相分离的情况, 幼儿是如何表征的, 也值得我们进行研究。不同文化对所有权权利的侧重不同, 提示我们有必要对所有权权利认知的发展进行跨文化检验。     

Subjective Well-Being and Policy

This paper analyses whether the aggregation of individual happiness scores to a National Happiness Index can still be trusted once governments have proclaimed their main objective to be the pursuit—or even maximization—of this National Happiness Index. The answer to this investigation is clear-cut: as soon as the National Happiness Index has become a policy goal, it can no longer be trusted to reflect people’s true happiness. Rather, the Index will be systematically distorted due to the incentive for citizens to answer strategically and the incentive for government to manipulate the Index in its favour. Such a distortion would arise even if the measurement of subjective well-being correctly reflected actual happiness before the intervention of government. Governments in a democracy should establish the conditions enabling individuals to become happy. The valuable and important results of happiness research should be introduced into the political process. Each person should be free to pursue happiness according to his or her preferences. This process is supported by obedience to the rule of law, human rights and free media, as well as by extended political participation rights, decentralized public decision-making, an open and effective education system fostering upward mobility and the possibility to find suitable employment.