Working memory outcomes following traumatic brain injury in children: A systematic review with meta-analysis

The aim of this review is to systematically examine the literature concerning multicomponent working memory (WM)—comprising a central executive (CE), two storage components (phonological loop, PL and visuo-spatial sketchpad, VSSP), and episodic buffer (EB)—in pediatric traumatic brain injury (TBI). Electronic searches were conducted of MEDLINE, PsychINFO and EMBASE up to October 2014 with the inclusion criteria of children and adolescents with TBI, and quantitative methods to assess at least one component of WM. Meta-analytic procedures calculated pooled effect sizes for WM outcomes. Of the studies examined, 27 met the inclusion criteria. Children with TBI exhibited deficits in the CE and PL, but not in the VSSP, and no study could be found which examined the EB. Qualitative analysis found that greater TBI severity was associated with poorer CE functioning in five out of nine studies. Differences in patterns of brain activation were evident in four out of five fMRI studies that examined WM in TBI children and controls. Deficits in CE were associated with poorer mathematical skills in the only study that examined relations between WM and academic deficits. Notwithstanding the heterogeneity of the studies reviewed, TBI places children at risk of WM deficits. Moreover, this meta-analysis suggests that various components of WM have differential vulnerability to pediatric TBI, with significant deficits found in the CE and PL, but not in the VSSP (although the VSSP has rarely been examined to date). Future studies should be theoretically driven, employ tasks assessing all components of the WM model and examine the functional ramifications (including academic outcomes) of WM deficits in this population.     

Time perception in severe traumatic brain injury patients: A study comparing different methodologies

In this study, we investigated time perception in patients with traumatic brain injury (TBI). Fifteen TBI patients and 15 matched healthy controls participated in the study. Participants were tested with durations above and below 1 s on three different temporal tasks that involved time reproduction, production, and discrimination tasks. Data variables analyzed included amount of errors, relative errors, and coefficient of variation. Both groups completed a neuropsychological battery that included measures of attention, working memory, and executive functions. Results revealed significant differences between groups on the time reproduction and discrimination tasks, whereas groups showed similar performance on the time production task. Correlation analyses showed involvement of attention, working memory and executive functions on the time reproduction and time discrimination tasks, but there was no involvement on the time production task. These findings suggest that TBI does not impact specific temporal function. Rather, impairments in attention, working memory and executive function abilities may explain lower temporal performance in people with TBI.     

Measuring post-traumatic stress: A psychometric evaluation of symptom- and coping questionnaires based on a Norwegian sample

The purpose of this study was to evaluate the psychometric characteristics of the Norweigian versions of the Impact of Event Scale, the Post Traumatic Stress Scale-10 item version and General Coping Questionnaire-30 item version. A group of 40 male and 56 female medical students was tested one week and four months after having started dissection of cadavers for the first time. The results showed that all scales had good internal consistency and test-retest reliability. The student sample scored lower on the IES and PTSS-10 than comparable groups of traumatized subjects. A gender difference emerged, with female subjects scoring higher than male subjects. The factor analysis of the instruments indicated good construct validity for the symptom scales. The analysis of content validity related to DSM IV criteria indicated that the IES and PTSS-10 may have some limitations in their predictive validity of PTSD. Taken together, the three scales have shown good psychometric properties and could be used in future research and clinical work.     

Impulsivity as a predictor of newly-diagnosed peptic ulcer disease: A prospective cohort study

We examined the role of impulsivity in the development of peptic ulcer disease (PUD). The subjects were initially healthy 4636 hospital employees aged 19–62 who responded to a questionnaire on personality, health habits, mental health, and PUD in 1998 and 2000. We used multivariate logistic analyses to determine the relationship between impulsivity and newly-diagnosed PUD among those employees who did not have PUD at baseline. Impulsivity was assessed with the Karolinska Scale of Personality. High level of impulsivity was associated with increased 2-year incidence of doctor-diagnosed PUD after adjustment of age, gender, education and shift work (odds ratio = 2.42, 95% confidence interval = 1.21–4.82). Additional adjustment for the effects of smoking, alcohol consumption, BMI, physical activity, minor psychiatric morbidity and diagnosed depression and other psychiatric disease had little effect on this relationship. The present study suggests that impulsivity may be a risk factor for the development of PUD.     

A human sound transducer/reproducer: Temporal capabilities of a profoundly echolalic child

Stimulus-echo latencies of a blind, severely echolalic child were measured to assess the capabilities of spontaneous transduction/reproduction of a verbal signal. Mean offset-to-onset latencies of 270 msec and onset-to-onset latencies of 792 msec are comparable to laboratory reaction times for syllable imitation. Results are considered within the theoretical context of physiological speech, i.e., externalized exposure of a psittacine level of verbal processing divorced from semantic, syntactic, lexical and, quite probably, phonological interference.     

Patterns of spontaneous recovery in aphasic groups: A study of adult stroke patients

The recovery of 31 aphasic stroke patients in the first three months postonset was investigated. Improvements on eight comprehension, repetition, and expression tasks were documented for four groups. These groups, retrospectively defined on the basis of initial scores on a fluency and a comprehension task, were: Low Fluency/Low Comprehension (LFLC), Low Fluency/High Comprehension (LFHC), High Fluency/Low Comprehension (HFLC), and High Fluency/High Comprehension (HFHC). Examination of each group's recovery revealed (1) equal improvement on nearly all language tasks for the two High Comprehension groups and (2) a more selective improvement largely in comprehension and imitation tasks for the two Low Comprehension groups. Implications of this selective improvement in initially low comprehending aphasics are discussed.     

Global self-evaluations and perceived instability of self in early adolescence: A cohort longitudinal study

A cohort longitudinal design with four adjacent cohorts of students ( n = 1689) followed over two years was used to study key issues identified in the research literature on the development of self-evaluations in early adolescence. There was no clear relationship between age/grade and self-evaluations. We found no support for a "stressful periods" hypothesis with respect to self: Possible changes were very gradual and quite small. However, there was a consistent "relative age" effect implying that younger students within a grade had more negative self-evaluations. There were small but consistent sex differences in self-evaluations in favor of the boys; more detailed analyses of very negative self-evaluations suggested that the early adolescent years are the period in which a sex difference in depression related symptomatology begins to emerge. Finally, the usefulness of some kind of effect size measure and advantages and problems associated with a cohort longitudinal design were discussed.     

Change and continuity in neurobehavioral development: lessons from the study of neurobiology and neural plasticity

The goal of this paper is to discuss our current understanding of change and continuity in neurobehavioral development. After describing the basic elements of neurobiological development, attention is focused on the myriad of ways experience influences the developing and developed brain. This literature is used to illustrate the complexity of both brain and behavioral development in the context of change and continuity. The implications of considering brain/behavior relations in the context of development comprise the final section of the paper.     

Weaning in Japan: A longitudinal study of mother and child behaviours during milk- and solid-feeding

Behaviours of seven Japanese mother-infant dyads during daytime feeding of both milk and solids were observed longitudinally to the middle of the second year. The first 3 months were a period of exclusive milk-feeding largely uninterrupted by mother-infant social interaction. In the following 6 months there was increasing mother-infant communicative interaction during milk-feeding and the mother began attempts to feed solids. After 8 months, weaning was promoted by reduction in some types of interaction during milk-feeding, and increased rejection by the infant of passive feeding as self-feeding of solids increased. Self-feeding was at first mainly by hand, and later with tools. A positive correlation was found between hand-feeding at 12-14 months and active physical stimulation of the infant by the mother during milk-feeding in the first year. Self-feeding of solids with tools increased significantly after 1 1/2 years, and the mother supported this development. The mother showed non-intentional eating-like mouth movement at the moment infants ate (empathetic behaviour), and this behaviour peaked in the latter half of the first year and decreased thereafter. The development of independence or autonomy in feeding was a mutual or cooperative process between mother and infant, and was initiated by the infant rather than imposed by the mother.     

Parents attributions of blame for the birth of a child with down syndrome: A pilot study

Abstract

Attributing blame to others for negative events is consistently associated with poor adjustment. We report here a study assessing whether failure to detect a problem on screening, in this case Down syndrome not detected during prenatal screening, is associated with blame and poor adjustment in parents. Twenty eight mothers and 23 fathers of children with Down syndrome were interviewed. Although no parent blamed themselves or their partner, eight fathers and five mothers blamed health professionals or the health care system in general for not preventing the birth of their children with Down syndrome prenatally. None of the parents who declined testing were blaming. Six of the 11 parents who received a negative test and seven of the 34 not offered a test blamed others. Both mothers and fathers who blamed others reported significantly higher parenting stress. Mothers, but not fathers, who blamed others were significantly more angry and depressed than those who did not.     

Nature of spelling errors in transcortical sensory aphasia: A case study

The nature and extent of spelling errors in a patient with transcortical sensory aphasia were investigated. The two experimental conditions required the patient to spell monosyllabic and polysyllabic words both verbally and in written form. Analysis of the spelling errors revealed partially preserved knowledge of the visual image of a word as a whole, as well as preserved knowledge of temporal order. Our patient's error patterns in both conditions were more similar than dissimilar. These findings in conjunction with results reported in the literature indicate that patients exhibiting different aphasia syndromes use separate spelling strategies.     

The retrieval of sentences from memory: A speed-accuracy study

A speed-accuracy tradeoff method was used to study the retrieval dynamics for recognition memory of parts of sentences. All sentences contained a subject, verb, object, location, and time. Recognition accuracy increased from chance at a processing time of about 0.5 sec to asymptotic accuracy at about 3 sec. The asymptotic accuracy levels for subject-verb, subject-object or verb-object recognition probes exceeded those of pair probes containing times or locations. This result suggests that the former may be more closely associated in semantic memory. The only difference among speed-accuracy curves was in asymptotic accuracy. The chance intercept and the rate of increase in accuracy were similar for all pair probes. A second finding was that the speed-accuracy curves for triple probes (e.g., subject-verb-object) were virtually identical to those of the comparable pair probes. These results appear to contradict a serial search hypothesis for the access of information from semantic memory. They support a parallel, direct-access hypothesis.     

The association of childhood intelligence with mortality risk from adolescence to middle age: Findings from the Aberdeen Children of the 1950s cohort study

There is growing evidence that childhood IQ is inversely associated with mortality in later life. However, the specificity of this association in terms of causes of death, whether it is continuous over the whole range of IQ scores and whether it is the same according to age and sex is not clear. In a large cohort (N = 11,603) of a complete population of children born in one city in the UK in the early 1950s, IQ measured at age 7 years (using a routinely administered picture test) was found to be inversely associated with mortality between the ages of 15 and 57 years. For every 1 SD increase in IQ at 7, the all cause mortality hazard ratio was 0.79 (95% CI 0.73, 0.85). On adjustment for a range of perinatal factors, father's social class at birth, number of sibs in the household and childhood height and weight, this was attenuated slightly to 0.81 (0.74, 0.88). Almost identical associations of IQ with mortality were seen for men and women as well as at younger (15–39) and older (40+) ages. These associations were across the entire IQ range, although some of the high mortality in the lowest category of IQ (< 70) was accounted for by causes associated with congenital disorders. Overall, external causes of death showed the strongest association, with weaker associations being seen for cancer. Further work is required to understand the mechanisms whereby childhood IQ has such a robust association with mortality in later life.     

A search for predictive factors in institute supervised cases: a retrospective study of 183 cases from 1959-1966 at the Boston Psychoanalytic Society and Institute.

The purpose of this project was to determine if it is possible to predict from the information contained in the write-ups of the preliminary evaluations of patients accepted for Institute supervised analyses those patients who would successfully complete their analyses and those who would not. Three raters independently studied the write-ups of 183 cases treated at the Boston Institute during the period 1959-1966. Each rater filled out a questionnaire of 105 items which were thought to be of possible predictive value. Outcomes were sought from the analysts who treated the patients. 130 outcomes were obtained and revealed that the patients fell into 4 distinctly different outcome groups: (Group 1) those who completed analysis by mutual agreement between the analyst and patient; (Group 2) those who prematurely terminated their analyses against the advice of their analysts; (Group 3) those whose analyses were prematurely interrupted by their analysts; (Group 4) those whose analyses became interminable. Statistical analyses were done to see which of the 105 predictor items distinguished these four distinct outcome groups. Many of the predictor items were not useful because they either showed no variation among patients, or were too often left blank, or were rated with very low interrater agreement. Of the remaining items, we found ten items which did show a highly significant difference between Group 1 patients and those patients in at least one of the other three outcome groups. We found five other predictor items which showed large, although not quite statistically significant, differences between Group 1 and at least one of the other three groups. Of these 15 items, 7 dealt with family history. The others concerned the patient's past history (2), object relationships (2), patient's sex (1), symptomatic state (1), field of endeavour (1), and history of previous psychotherapy (1). We found it made no difference in terms of these 4 outcome groups what the patient's diagnosis was or whether he was a 1st, 2nd, 3rd or 4th supervised case. Among the other negative findings were patient's age and the ability to experience and tolerate felt anxiety. These did not distinguish any of the outcome groups. These findings show that additional predictively useful information is present in the preliminary evaluations of patients already screened and accepted for Institute analysis by trained evaluators. These results suggest that one particularly important area on which to focus future attention is family history.     

Job stressors, emotional exhaustion, and need for recovery: A multi-source study on the benefits of psychological detachment

This paper examines psychological detachment (i.e., mentally “switching off”) from work during non-work time as a partial mediator between job stressors and low work-home boundaries on the one hand and strain reactions (emotional exhaustion, need for recovery) on the other hand. Survey data were collected from a sample of protestant pastors (N = 136) and their spouses (N = 97). Analyses showed that high workload, emotional dissonance, and low spatial work-home boundaries were related to poor psychological detachment from work during non-work time. Poor psychological detachment in turn predicted high levels of emotional exhaustion and need for recovery. Psychological detachment was a partial mediator between job stressors and strain reactions. This study avoids same-source bias and demonstrates the importance of psychological detachment in the stressor–strain relationship.     

Effects of a self-regulation intervention on exercise are moderated by depressive symptoms: A quasi-experimental study

This study investigated whether a computer-based self-regulation intervention increases physical exercise in individuals with or without depressive symptoms. A total of 361 individuals in orthopedic rehabilitation, 36 of them with depressive symptoms, were recruited in Germany. In a quasi-experimental study, individuals were allocated to either a computer-based self-regulation intervention or an online questionnaire. Exercise was measured at the beginning of rehabilitation and six weeks after rehabilitation. Depressive symptoms were assessed at the end of rehabilitation. An analysis of covariance was conducted, controlling for exercise baseline, sex, and phase of assessment. A main effect for depressive symptoms (p = .005) and intervention group (p = .011), as well as a marginal interaction of intervention x depressive symptoms were found (p = .076). Results indicate that the self-regulation exercise intervention in an orthopedic rehabilitation setting seem to be only effective in non-depressed individuals. Future research should examine how health behavior change programs can be designed more effectively for individuals with depressive symptoms.     

Childhood antecedents of Agreeableness: A longitudinal study from preschool to late adolescence

Although the consensus view is that Agreeableness originates from childhood difficultness and regulatory deficits, few studies have investigated such assumptions longitudinally. In this study, we examined this issue by assessing enduring and mediating effects of self-regulation as well as the impact of parenting behaviors on the development of Agreeableness from preschool to late adolescence. Longitudinal data from 965 Norwegian families following children from 1.5 years to 16.5 years were used. Path analyses revealed childhood difficultness at age 4 to be related to Agreeableness at age 16.5; this effect was mediated through emotion regulation in late childhood. However, such mediation effects were primarily found when parents used punitive practices towards their children. Our findings point to personality coherence throughout development.     

Longitudinal study of quality of life in acquired brain injury: A self- and proxy-report evaluation

Background/ObjectiveAfter an acquired brain injury (ABI), the person remains with several impairments and disabilities that cause a decrease in his/her quality of life (QoL), which could change over time. The objective of the study was to analyse the evolution patterns of QoL in a sample of persons with ABI for one-year as well as the differences in proxy- and self-report versions of a QoL instrument. Method: The sample comprised 402 persons with ABI with ages ranging between 18 and 91 years, whom 36.20% had had the accident recently (i.e., three years or less). Patients, professionals and relatives responded at three evaluation points to the CAVIDACE scale, an ABI-specific QoL tool. Results: ANOVAs showed an improvement in QoL in the two follow-ups; the improvement was especially significant in the period between baseline and six months. The respondent factor did not interact with the evaluation time, but significant differences were found between respondents, with scores of patients higher than that for proxies. Finally, the QoL’s evolution interacts with the time elapsed since injury, showing significant improvements in the most recent group (i.e., three years or less). Conclusions: QoL must be considered from the earliest moments after ABI to obtain more significant improvements.