动态性对简笔画动物审美的影响及其神经机制

运用行为和fMRI技术, 通过比较动态刺激与静态刺激审美判断的行为和脑机制的异同探讨动态性对简笔画动物审美的影响, 包括两个实验。结果发现, 动态简笔画动物的美观程度评分和喜欢程度评分都显著高于静态简笔画动物。同时, 动态简笔画动物审美判断激活的区域基本涵盖了静态简笔画动物审美所激活的区域, 二者都激活了枕叶区等视觉加工区域、额叶区等认知加工区域、眶额叶皮层等奖赏区域以及海马、脑岛、扣带回、杏仁核等情绪加工区域。与静态简笔画动物的审美相比, 动态简笔画动物的审美显著激活了双侧舌回、双侧MT。本研究结果表明, 动态性影响了对简笔画动物的审美, 动态简笔画动物比静态简笔画动物被判断为更加美观。     

记忆汉字和英语单词的差异脑区研究

通过英文词和汉字的记忆实验,探讨储存和提取不同阶段汉字与英文的脑加工差异。采用经典的"学习-再认"实验范式,8名大学生进行英文与汉字记忆和再认测验,fMRI采集数据,AFNI软件进行预处理、多元回归及ANOVA组分析统计语言差异。结果显示:汉字记忆减英文记忆激活右扣带回;英文记忆减汉字记忆激活右颞上回(BA38)、左扣带回(BA31)、左小脑扁桃体。汉字再认减英文再认的差异脑区为小脑扁桃体、左颞上回。英文再认减汉字再认在0.05水平上没有脑区差异。汉字记忆激活左侧梭状回、右舌回、左顶上小叶、左额下回;英文记忆激活右舌回、左内侧前额叶、左中央前回、左额中回。汉字再认激活左枕下回、左顶下小叶、右额下回、左额中回、右豆状核、左小脑扁桃体、左颞上回、右内侧前额叶。英文再认激活右舌回、左额上回、左顶下小叶、额下回、左中央前回、右顶上小叶、豆状核、右侧尾状核、左中央后回、左侧丘脑。本研究发现:(1)记忆的差异性统计激活颞叶,表明颞叶是记忆存储脑区;(2)学习和记忆阶段有额叶、顶叶激活,表明这些脑区参与文字加工;(3)英文再认比汉字再认激活更多脑区,花费更多的脑资源。     

风险决策的神经机制:基于啮齿类动物研究

风险决策是在不同选项的结果确定、并且结果出现的概率已知情况下的决策。啮齿类风险决策模型研究发现前额皮层-杏仁核-伏隔核神经环路联系是决定风险决策的选择倾向的关键。前额皮层中的眶额皮层和内侧前额皮层参与风险决策的策略形成和策略转换有关;而皮层下核团中的杏仁核、腹侧纹状体的伏隔核等结构参与策略保持、价值判断,影响决策偏向和行动强度;眶额皮层、伏隔核神经元和多巴胺神经元编码风险决策过程中的概率、风险等因素;此外,多巴胺等单胺类神经递质及受体在风险决策中有复杂的作用。     

读写分离的脑神经机制：来自fMRI的证据

使用只读不写的繁体字和会读会写的简体字材料, 以默读为实验任务, 探讨“会读会写”与“只读不写”文字的加工脑区。8名在校大学生在磁共振扫描过程中默读呈现的繁体字或简体字, 采用ANOVA统计全脑激活图。与简体字相比, 繁体字额外激活了右额下回、左小脑。在功能连接性上, 简体字和繁体字相同的激活脑区有左楔前叶-左内侧前额叶, 左楔前叶-左中央前回, 右枕中回-左舌回; 不同的是, 繁体字左楔前叶与右额下回有高相关, 而简体字左楔前叶与右额中回有高相关。左内侧前额叶与中央前回只在繁体字中表现出高相关。繁体字和简体字任务的T检验差异脑区包括左颞中回和右顶下小叶。只读不写的文字具有加工的整体性和轮廓性特征, 它的读音与不规则简体字相似, 具有整字加工特点。繁体字和简体字加工具有相同的功能连接区, 但也存在差异。右脑表现为连接脑区不同, 左脑内侧前额叶与中央前回表现为相关性不同, 说明内侧前额叶-中央前回在繁体字加工中起着重要作用。实验结果还证明顶叶是记忆再认的主要脑区。     

基于“心理痛苦”理论的眶额皮质介导抑郁症自杀机制

近年来,自杀的心理痛苦三因素模型(包括痛苦唤醒、痛苦体验和痛苦逃避)在临床抑郁症患者群体得到验证。痛苦逃避是该模型的核心成分。行为学研究证据显示,痛苦逃避维度得分对抑郁症患者自杀意念和自杀行为的预测力远高于Beck抑郁问卷得分和痛苦体验得分。由于眶额皮质是介导情绪反应和控制复杂行为的关键界面,主要参与负性情绪引发回避惩罚(痛苦)的动机控制,与动机、决策和行为监控密切相关。眶额皮质及其与前额叶、皮层下结构(扣带前回、杏仁核和下丘脑等)的异常激活模式可能是痛苦体验引发高逃避动机、进而产生自杀行为(风险决策)的重要神经基础。本文在综述以往研究的基础上,提出通过改编和发展情感激励延迟和金钱激励延迟的认知任务,对痛苦体验和痛苦逃避动机阶段进行时间上的分离,建立眶额皮质介导抑郁症自杀的脑功能病理模型的研究思路。     

积极情绪加速心血管反应恢复的自主神经活动机制

通过对不同情绪唤醒状态下的心率变异性（HRV）和呼吸性窦性心率不齐（RSA）分析,探讨了积极情绪加速高唤醒消极情绪引起的心血管反应向基线恢复的自主神经活动机制。实验表明：与在观看高唤醒恐惧影片结束后观看悲伤影片和中性视频比较,观看高唤醒恐惧影片结束后观看快乐影片加速了高唤醒恐惧影片引起的心率、指脉等心血管反应向基线的恢复;与在观看高唤醒恐惧影片结束后观看悲伤视频和中性视频材料比较,观看高唤醒恐惧影片结束观看快乐影片后的恢复期,被试的迷走神经激活水平迅速增强,迷走神经激活水平甚至超过基线期。因此,积极情绪加速高唤醒消极情绪刺激引起的心血管反应向基线恢复,其自主神经活动机制是在积极情绪状态下个体有更强的迷走神经激活。     

面孔审美加工的神经机制及个体差异

外显和内隐的面孔审美加工的脑成像研究表明,美的面孔比不美的面孔导致眶额皮层、伏隔核、杏仁核等奖赏脑区更大的激活。脑电研究则发现了与面孔审美加工有关的早期负波和晚期正成分。面孔审美加工有关的脑区活动也受到性别、生理周期等个体因素的调节。未来的研究需要比较美的面孔与其它奖赏刺激加工的神经机制,探讨面孔审美加工的不同阶段及时间进程,在面孔知觉的框架下形成合理的面孔审美加工的神经模型。     

中性抽象词和具体词情绪信息获得的差异

采用词汇迫选学习范式考察不同类型词汇获得情绪信息的认知机制。结果发现：（1）在迫选过程中与积极图片匹配的具体词汇喜好度显著高于与消极图片匹配的喜好度,而抽象词学习并未表现出这样的效应。（2）积极图片下被选择词汇的喜好度显著高于未被选择词汇的喜好度,而消极图片下被选择词汇与未被选择词汇的喜好度差异不显著。该结果表明具体词相较于抽象词更易获得相应情绪信息,积极情绪比消极情绪信息更易被习得。     

顿悟体验的特性、结构和功能基础

顿悟体验是伴随顿悟问题解决过程的心理和现象学体验,主要包含伴随题解闪现的啊哈体验和因思维定势自动激活而催生的僵局阶段体验。现有研究显示,顿悟体验可能是多类认知与情绪要素构成,兼具认知和情绪加工特性的多维复合体。加工流畅性可部分解释顿悟体验的产生机制,杏仁核、眶额区和脑岛等情绪和奖赏加工的脑区则可能是其脑功能基础。未来须用多元方法从新旧交替视角深化两阶段顿悟体验的研究。     

情绪唤起对执行功能的作用

执行功能是对基本认知加工进行有意心理控制的所有高级认知过程.最近10年,情绪唤起对执行功能的作用机制吸引愈来愈多的研究兴趣,其中,消极情绪(尤其焦虑、抑郁)已被普遍证实损害执行功能的运行效率;积极情绪如何作用执行功能尚不明确.鉴于后者研究中的理论假设匮乏,近年兴起的积极情绪的扩展建构理论以及动机维度模型,能为理解积极情绪如何作用执行功能提供线索与启发.未来研究应深入探讨不同动机强度的积极及消极情绪对执行功能的作用机制,在这之中也应细致区分情绪唤起与情绪刺激的不同效应.     

Processing emotional pictures and words: Effects of valence and arousal

There is considerable debate regarding the extent to which limbic regions respond differentially to items with different valences (positive or negative) or to different stimulus types (pictures or words). In the present event-related fMRI study, 21 participants viewed words and pictures that were neutral, negative, or positive. Negative and positive items were equated on arousal. The participants rated each item for whether it depicted or described something animate or inanimate or something common or uncommon. For both pictures and words, the amygdala, dorsomedial prefrontal cortex (PFC), and ventromedial PFC responded equally to all high-arousal items, regardless of valence. Laterality effects in the amygdala were based on the stimulus type (word 5 left, picture 5 bilateral). Valence effects were most apparent when the individuals processed pictures, and the results revealed a lateral/medial distinction within the PFC: The lateral PFC responded differentially to negative items, whereas the medial PFC was more engaged during the processing of positive pictures.     

Amygdala responses to emotionally valenced stimuli in older and younger adults

Abstract— As they age, adults experience less negative emotion, come to pay less attention to negative than to positive emotional stimuli, and become less likely to remember negative than positive emotional materials. This profile of findings suggests that, with age, the amygdala may show decreased reactivity to negative information while maintaining or increasing its reactivity to positive information. We used event-related functional magnetic resonance imaging to assess whether amygdala activation in response to positive and negative emotional pictures changes with age. Both older and younger adults showed greater activation in the amygdala for emotional than for neutral pictures; however, for older adults, seeing positive pictures led to greater amygdala activation than seeing negative pictures, whereas this was not the case for younger adults.     

Mindful attention predicts greater recovery from negative emotions,but not reduced reactivity

This study investigated the role of dispositional mindful attention in immediate reactivity to, and subsequent recovery from, laboratory-induced negative emotion. One hundred and fourteen undergraduates viewed blocks of negative pictures followed by neutral pictures. Participants’ emotional responses to negative pictures and subsequent neutral pictures were assessed via self-reported ratings. Participants’ emotional response to negative pictures was used to index level of emotional reactivity to unpleasant stimuli; emotional response to neutral pictures presented immediately after the negative pictures was used to index level of emotional recovery from pre-induced negative emotion (residual negativity). Results indicated that mindful attention was not associated with the emotional response to negative pictures, but it was associated with reduced negative emotion in response to the neutral pictures presented immediately after the negative pictures, suggesting better recovery as opposed to reduced reactivity. This effect was especially pronounced in later experimental blocks when the accumulation of negative stimuli produced greater negative emotion from which participants had to recover. The current study extends previous findings on the relationship between dispositional mindfulness and reduced negative emotion by demonstrating that mindful attention may facilitate better recovery from negative emotion, possibly through more effective disengagement from previous stimuli.     

A misleading feeling of happiness: metamemory for positive emotional and neutral pictures

Emotional information is often remembered better than neutral information, but the emotional benefit for positive information is less consistently observed than the benefit for negative information. The current study examined whether positive emotional pictures are recognised better than neutral pictures, and further examined whether participants can predict how emotion affects picture recognition. In two experiments, participants studied a mixed list of positive and neutral pictures, and made immediate judgements of learning (JOLs). JOLs for positive pictures were consistently higher than for neutral pictures. However, recognition performance displayed an inconsistent pattern. In Experiment 1, neutral pictures were more discriminable than positive pictures, but Experiment 2 found no difference in recognition based on emotional content. Despite participants’ beliefs, positive emotional content does not appear to consistently benefit picture memory.     

Ecstasy and agony: activation of the human amygdala in positive and negative emotion

Considerable evidence indicates that the amygdala plays a critical role in negative, aversive human emotions. Although researchers have speculated that the amygdala plays a role in positive emotion, little relevant evidence exists. We examined the neural correlates of positive and negative emotion using positron emission tomography (PET), focusing on the amygdala. Participants viewed positive and negative photographs, as well as interesting and uninteresting neutral photographs, during PET scanning. The left amygdala and ventromedial prefrontal cortex were activated during positive emotion, and bilateral amygdala activation occurred during negative emotion. High-interest, unusual photographs also elicited left-amygdala activation, a finding consistent with suggestions that the amygdala is involved in vigilance reactions to associatively ambiguous stimuli. The current results constitute the first neuroimaging evidence for a role of the amygdala in positive emotional reactions elicited by visual stimuli. Although the amygdala appears to play a more extensive role in negative emotion, it is involved in positive emotion as well.     

个体神经质水平对情绪加工的影响 ——事件相关电位研究

采用事件相关电位方法探讨个体神经质水平对情绪加工的影响,测量并比较了神经质高水平个体和神经质低水平个体观看三类图片（积极、中性和消极）时的事件相关电位。结果发现,P120、N130、P230和N250成分的刺激效价主效应显著,积极、消极情绪刺激与中性刺激诱发的ERP差异最早开始于刺激呈现后的120ms左右。其次,在额叶和额中央部位的晚正电位上,神经质水平与刺激效价交互作用显著,神经质高分组与低分组对消极情绪刺激的反应有明显差异,而两组被试对积极、中性刺激的反应没有表现出差异。结果支持神经质与消极情绪相关,个体的神经质水平主要影响额叶和额中央叶的晚期负性情绪加工     

特质焦虑个体在高难度Stroop任务下的情绪启动效应

通过问卷法,选取特质焦虑和非特质焦虑被试作为本实验的研究对象,考察了正性、负性、中性三种不同的情绪对不同特质焦虑个体认知抑制的影响。在Stroop任务之前呈现三种情绪图片,结果发现,相比非特质焦虑被试,特质焦虑被试的Stroop效应量更大;特质焦虑被试和非特质焦虑被试在正性和负性情绪条件下的Stroop效应量均更大。说明特质焦虑被试的认知抑制功能存在不足,正性和负性情绪对特质焦虑和非特质焦虑被试的认知抑制均存在阻碍作用。     

情绪大脑机制研究的进展

文章综述情绪大脑机制研究的最新进展。情绪的脑机制——大脑回路,包括前额皮层、杏仁核、海马、前部扣带回、腹侧纹状体等。前额皮层中的不对称性与趋近和退缩系统有关,左前额皮层与趋近系统和积极感情有关,右前额皮层与消极感情和退缩有关。杏仁核易被消极的感情刺激所激活,尤其是恐惧。海马在情绪的背景调节中起着重要作用。前额皮层和杏仁核激活不对称性的个体差异是情绪个体差异的生理基础。情绪的中枢回路有可塑性。     

负性情绪刺激对大学生多目标追踪能力的影响

探讨了负性情绪对大学生多目标追踪能力的影响以及其影响机制。实验要求被试在观看国际情绪图库中的负性或中性图片后,完成多目标追踪和点探测任务,同时设置基线条件作为对照。采用状态-特质焦虑量表和贝克抑郁自评量表考察不同情绪图片条件下被试的诱发情绪状态。研究结果发现：（1）被试观看负性情绪图片后状态焦虑程度和抑郁量表评分显著提高,观看情绪图片有效诱发了被试的负性情绪;（2）基线条件下的被试追踪正确率显著低于中性条件,基线条件和负性图片条件下的追踪正确率无差异,说明训练可以提高被试的多目标追踪能力,但负性情绪抑制了被试在基线追踪任务中的训练效果;（3）负性图片条件下的点探测觉察率显著低于中性图片条件,说明负性情绪影响了被试的注意资源分配。研究结果表明：负性情绪可能干扰了被试目标导向的注意系统,使得个体更易受刺激驱动的注意系统影响,并且在追踪过程中影响被试中央执行系统的抑制和转移功能。     

Effects of incidental positive emotion and cognitive reappraisal on affective responses to negative stimuli

Previous studies have identified two powerful ways to regulate emotional responses to a stressor: experiencing incidental positive emotions and using cognitive reappraisal to reframe the stressor. Several cognitive and motivational theories of positive emotion support the formulation that incidental positive emotions may facilitate cognitive reappraisal. To test the separate and interacting effects of positive emotions and cognitive reappraisal, we first adapted an established picture-based reappraisal paradigm by interspersing blocks of positive emotion inducing and neutral pictures. Across two pre-registered studies (Studies 1, 2), reappraisal effectively decreased self-reported negative emotions and increased self-reported positive emotions; however, experiencing incidental positive emotions did not facilitate reappraisal success. In another preregistered study (Study 3), we employed a more powerful positive emotion induction via virtual reality (VR), used a social stress anticipation task, and instructed participants to reappraise the anticipated stressor positively. Although there was a robust effect of the positive emotion induction (relative to the neutral induction) on feeling more positive emotions throughout stress anticipation, the results again indicated that incidental positive emotions did not facilitate cognitive reappraisal. We propose that incidental positive emotions and cognitive reappraisal may constitute separate pathways of influence when regulating one's responses to negative events.