首页 | 本学科首页   官方微博 | 高级检索  
相似文献
 共查询到20条相似文献,搜索用时 31 毫秒
1.
Abstract

The theme of the Twenty-Third Georgetown University Symposium on Family Theory and Family Psychotherapy, held November 8 and 9,1986, in Washington, DC, was Toward a Science of Human Behavior. The program included famed sociobiologist Edward O. Wilson as the Distinguished Guest Lecturer; a special panel discussion about what is involved in moving toward a science of human behavior; a presentation by Murray Bowen, Director of the Georgetown University Family Center; a presentation by Walter Toman, who is well-known for his research on sibling position; and 10 other presentations related to various aspects of family systems theory and therapy.  相似文献   

2.
Segmentation of target odorants from background odorants is a fundamental computational requirement for the olfactory system and is thought to be behaviorally mediated by olfactory habituation memory. Data from our laboratory have shown that odor-specific adaptation in piriform neurons, mediated at least partially by synaptic adaptation between the olfactory bulb outputs and piriform cortex pyramidal cells, is highly odor specific, while that observed at the synaptic level is specific only to certain odor features. Behavioral data show that odor habituation memory at short time constants corresponding to synaptic adaptation is also highly odor specific and is blocked by the same pharmacological agents as synaptic adaptation. Using previously developed computational models of the olfactory system we show here how synaptic adaptation and potentiation interact to create the observed specificity of response adaptation. The model analyzes the mechanisms underlying the odor specificity of habituation, the dependence on functioning cholinergic modulation, and makes predictions about connectivity to and within the piriform neural network. Predictions made by the model for the role of cholinergic modulation are supported by behavioral results.Filtering sensory input is critical for information processing tasks such as background segmentation, and shifting processing power away from redundant, stable, or repetitive stimuli toward dynamic, novel stimuli. A critical aspect of this filtering however, is stimulus specificity. Under most circumstances it may be most beneficial to selectively filter the redundant stimulus, while maintaining responsiveness to different, though perhaps highly similar stimuli.In the olfactory system, short-term habituation to stable or repeated odorants involves a metabotropic glutamate receptor (mGluR)-dependent depression of afferent synapses to the piriform cortex (Best and Wilson 2004). Blockade of group III mGluR receptors prevents cortical adaptation odors (Best and Wilson 2004), and reduces short-term habituation of odor-evoked reflexes (Best et al. 2005) and odor investigation (Yadon and Wilson 2005; Bell et al. 2008; McNamara et al. 2008). This short-term habituation is highly odor specific, with minimal cross-adaptation of piriform cortical single-unit responses or cross-habituation of behavioral responses to similar odors, including between mixtures and their components (Wilson 2000; Cleland et al. 2002). Interestingly, there is an experience-dependent component to short-term habituation odor specificity. The odor specificity is most pronounced for familiar odors, with very brief (<20 sec) exposure to odors producing more generalization, and longer exposures (>50 sec) sufficient to permit strong odor specificity in cortex adaptation (Wilson 2003).The homosynaptic nature of afferent synaptic depression underlying cortical adaptation (Wilson 1998; Best and Wilson 2004) may contribute to this odor specificity. However, the experience dependence suggests that there may be an additional process involved. In fact, theoretical views of piriform cortical function suggest that the cortex learns previous patterns of input via potentiation of intracortical association fiber synapses (Hasselmo et al. 1990; Barkai et al. 1994; Haberly 2001; Linster et al. 2003). This autoassociative process essentially creates a template of previous network activity, against which new input patterns can be compared, allowing enhanced discrimination between similar patterns, as well as completion of degraded patterns (Barkai et al. 1994; Barnes et al. 2008). In support of this hypothesis, previous work has demonstrated that disruption of normal synaptic potentiation in association fiber synapses through blockade of cholinergic muscarinic receptors (Patil et al. 1998; Linster et al. 2003), reduces odor specificity of cortical adaptation (Wilson 2001b), prevents the effects of odor experience on subsequent behavioral cross-habituation (Fletcher and Wilson 2002), and disrupts odor discrimination (Linster et al. 2001).The present series of studies further explored the role of combined afferent synaptic depression and intracortical association fiber synaptic potentiation on the specificity of cortical adaptation and odor habituation. Using a computational model of the olfactory system (Linster et al. 2007), the results suggest that activity-dependent association fiber plasticity is necessary to account for the specificity of odor habituation. Furthermore, in behavioral experiments blockade of cholinergic muscarinic receptors during habituation enhances generalization of odor habituation, consistent with the modeling and with previous electrophysiological results.  相似文献   

3.
Nearly 70 years ago, eminent mathematician Edwin Bidwell Wilson attended a dinner at Harvard where visitor Charles Spearman discussed the "two-factor theory" of intelligence and his just-released book The Abilities of Man. Wilson, having just discovered factor indeterminacy, attempted to explain to Spearman and the assembled guests that Spearman's two-factor theory might have a non-uniqueness problem. Neither Spearman nor the guests could follow Wilson's argument, but Wilson persisted, first through correspondence, later through a series of publications that spanned more than a decade, involving Spearman and several other influential statisticians in an extended debate. Many years have passed since the Spearman-Wilson debates, yet the fascinating statistical, logical, and philosophical issues surrounding factor indeterminacy are very much alive. Equally fascinating are the sociological issues and historical questions surrounding the way indeterminacy has periodically vanished from basic textbooks on factor analysis. In this article, I delineate some of these historical-sociological issues, and respond to a critique from some recent commentators on the history of factor indeterminacy.  相似文献   

4.
5.
The goal of this paper is to make headway on a metaphysics of social construction. In recent work (forthcoming), I’ve argued that social construction should be understood in terms of metaphysical grounding. However, I agree with grounding skeptics like Wilson (Inquiry 1–45, 2014) that bare claims about what grounds what are insufficient for capturing, with fine enough grain, metaphysical dependence structures. To that end, I develop a view on which the social construction of human social kinds (e.g., race) is a kind of realization relation. Social kinds, I argue, are multiply realizable kinds. I depart from the Wilson by further arguing that an appeal to grounding is not otiose when it comes to social construction. Social construction, I claim, belongs to the “big-G” Grounding genus, but it is the specific “small-g” relation of realization at work in cases of human kind social construction.  相似文献   

6.
Two modifications to the Lewis and Wilson (1970) infant stabilimeter are described which will provide increased sensitivity and further reduce overall cost of manufacture.  相似文献   

7.
肝豆状核变性(wilson’s病)是一种铜代谢异常的遗传性疾病,肝移植是治疗Wilson’s病的良好方法。我院器官移植中心于2007年6月至2008年6月期间应用脾窝异位辅助性活体肝脏移植治疗肝豆状核变性4例,在评估治疗效果和总结经验的同时,我们对这一治疗方法进行了几点思考,并对其伦理学争议进行了讨论。脾窝异位辅助性活体肝移植为治疗Wilson’s提供一条有效的、安全的、简单的全新途径。  相似文献   

8.
The Practice of Argumentative Discussion   总被引:4,自引:0,他引:4  
I propose some changes to the conceptions of argument and of argumentative discussion in Ralph Johnson's Manifest Rationality (2000). An argument is a discourse whose author seeks to persuade an audience to accept a thesis by producing reasons in support of it and discharging his dialectical obligations. An argumentative discussion (what Johnson calls argumentation) is a sociocultural activity of constructing, presenting, interpreting, criticizing, and revising arguments for the purpose of reaching a shared rationally supported position on some issue. Johnson's theory of argumentative discussion, with occasional modifications, is derived from this definition as a sequence of 17 theorems. Argumentative discussion is a valuable cultural practice; it is the most secure route to correct views and wise policies.  相似文献   

9.
The conservatism construct has previously proved predictive of social and psychological dimensions having both practical and theoretical relavance. Its potential, however, has typically been limited by measurement imprecision due principally to the use of lengthy and potentially ambiguous verbal statements subject to either intentional or unintentional response bias. Wilson and Patterson's recently developed Conservatism Scale (C-scale) is intended to obviate the more critical sources of bias inherent in the traditional conservatism measures. In an extended test of the C-scale's validity, the present study finds 12 categories of "known groups" scoring as theoretically expected, and further shows C-scale scores consistently and significantly correlated with eight theoretically related dimensions.  相似文献   

10.
This article examines the medical discourse that formed the foundations of what mental health professionals today call Attention Deficit Hyperactivity Disorder (ADHD). The article examines literature from two medical discussions: 1) the discussion of "imbecility" and "idiocy" in the late 19th and early 20th centuries in Western Europe and in the United States; and 2) the diagnosis of encephalitis lethargica in children during the 1920s. The diagnosis of encephalitis lethargica was heavily influenced by the previous discussion of imbecility and occupied a seminal place in the history of medicalizing child behavior. It served as a specific disease category for kids who demonstrated unconventional behavior in a variety of social contexts. It will be argued that the discussion of encephalitis lethargica began a research modality in psychiatry which sought to find neurological bases for childhood deviance, typified by the contemporary discussion of ADHD.  相似文献   

11.
Fifty-three tests designed to measure aspects of creative thinking were administered to 410 air cadets and student officers. The scores were intercorrelated and 16 factors were extracted. Orthogonal rotations resulted in 14 identifiable factors, a doublet, and a residual. Nine previously identified factors were:verbal comprehension, numerical facility, perceptual speed, visualization, general reasoning, word fluency, associational fluency, ideational fluency, and a factor combining Thurstone'sclosure I andII. Five new factors were identified asoriginality, redefinition, adaptive flexibility, spontaneous flexibility, andsensitivity to problems.Under Contract N6onr-23810 with the Office of Naval Research. The opinions expressed are our own and are not necessarily shared by the Office of Naval Research. These studies are under the direction of J. P. Guilford. Paul R. Christensen is assistant director. Robert C. Wilson has been principally responsible for the conduct of this particular study. Donald J. Lewis contributed to the development of hypotheses and tests. Raymond M. Berger made substantial contributions to the development of the tests.The authors are very much indebted to the Personnel Research Laboratory, Human Resources Research Center, Air Training Command, Lackland Air Force Base, Texas, for making the testing possible, and in particular to Dr. Lloyd G. Humphreys, Director, and to Mr. William B. Lecznar, Technical Aide.Acknowledgement is made to Gordon Taaffe for the supervision of much of the statistical work connected with this study and to Norman W. Kettner for carrying out the extractions of factors and for valuable assistance on the rotations of axes.A fuller discussion of this factor analysis is given by Wilson (16).  相似文献   

12.
I discuss an objection by Margaret Wilson against Robert Brandom's interpretation of Leibniz's account of perceptual distinctness. According to Brandom, Leibniz holds that (i) the relative distinctness of a perception is a function of its inferentially articulated content and (ii) apperception, or awareness, is explicable in terms of degrees of perceptual distinctness. Wilson alleges that Brandom confuses ‘external deducibility’ from a perceptual state of a monad to the existence of properties in the world, with ‘internally accessible content’ for the monad in that state. Drawing on Leibniz, I develop a response to Wilson on Brandom's behalf.  相似文献   

13.
The sensitive case presentation by Barbara Springer Edwards and Winston M. Ueno, concerning a patient's desire to be sedated and disconnected from a respirator, furnishes much material for discussion. One issue: When a patient refuses treatment, what are the limits of the health-care provider's obligation to persuade the patient to accept or continue with treatment? I say "limits" advisedly, for the obligation has both a floor (the least that one must attempt) and a ceiling (beyond which efforts to persuade become medical harassment).... Another point concerns the language we all use to describe the experiences of patients. My wife, Barbara, rails at how doctors use the terms "distress" and "discomfort" -- a usage that, she points out, has infected her husband as well. She is right to rail. Someone who calls the suffocation caused by disconnecting a respirator "distressing" or "uncomfortable" will call the Gulf War a "spat."... The main issue this discussion by Edwards and Ueno raises for me, though, is that of the manner and meaning of dying.  相似文献   

14.
The effect of the cultural values of rationalization and individualism upon the status of the parish minister is discussed. These values make the minister's status precarious because role behavior is difficult to interpret in terms of them. Some defenses against precariousness are outlined.This paper was read at the session, Ministry Studies: The Contribution of Samuel W. Blizzard, convened at the annual meeting of the Religious Research Association, Milwaukee, Wisconsin, October 1975. The late Samuel Wilson Blizzard was Maxwell M. Upson Professor of Christianity and Society at Princeton Theological Seminary.  相似文献   

15.
While some previous research has suggested that group discussion may facilitate eyewitness accuracy, other research has drawn attention to the potential dangers of such discussion. The present studies examine this controversy and the interaction between accuracy and agreement following group discussion. It was found that individuals tend to agree in their testimony following group discussion, and are liable to change their original replies to bring themselves into agreement with group leaders' recall. A second experiment focused upon the actual items which witnesses agreed on following discussion. Changing the mode of questioning from interrogative to narrative eliminated differences in magnitude of agreement between discussion and no-discussion groups. As narrative recall leads to reporting of "easy" items, it was suggested that only certain "difficult" items are susceptible to discussion effects. The need for caution regarding the reliance on testimony following witness discussion was stressed.  相似文献   

16.
S Breuer 《Psyche》1992,46(1):1-31
The author recapitulates various conceptions of narcissism that are in psychoanalytic discussion and attempts to set up a new theoretical frame for the socio-psychological topoi "authoritarian character" and "narcissistic personality" by means of Kohut's conceptions of the "grandiose self" and the "idealized parental imago". Based on M. Mahler's observations, Kernberg's critique of Kohut is rejected.  相似文献   

17.
Traditionally, constitutionalists have offered just one notion of constitution to analyse the relation that an object, such as a statue or a chain, bears to the object/s from which it is made: let us say, a piece of marble in the first case or a piece of metal in the second. Robert Wilson proposes to differentiate two notions of constitution and, in this way, to offer constitutionalists a more varied range of metaphysical tools. To justify the introduction of the difference, he presents several phenomena and problems, the explanation of which would justify the distinction he makes. In this paper I argue that Wilson’s proposal would not increase the explanatory power of a theory of constitution as it has traditionally been understood, only its complexity. Increasing the complexity without increasing the explanatory power of a theory, I defend, goes against one, at least prima facie, basic theoretical virtue: parsimony. In my argumentation I crucially use, for the case of Wilson’s first three arguments, the existence of principles of existence?persistence, which constitutionalists, Wilson among them, usually accept. In arguing against Wilson’s fourth argument I use a slightly modified version of Lynne Rudder Baker’s theory of constitution.  相似文献   

18.
The purpose of this paper is to show that conscientious objection (henceforth CO) to military service is essentially not a dilemma of freedom of conscience versus the duty to obey the law, but above all a dilemma between two conflicting patriotic moral obligations. Furthermore, the paper demonstrates that CO is justifiable on the basis of what is known as moderate patriotism, that is, out of a patriotism which is committed simultaneously to universal and particular values. The paper begins with a critical discussion of theoretical weaknesses in liberal thought of CO. Then, the concept of moderate patriotism is presented, followed by a discussion of the notion of patriotic CO (PCO). The next stage presents a step Towards A Theory of PCO to Military Service and shows how it differs from other liberal theories of disobedience. The conclusion is that if CO on patriotic grounds is morally justifiable, it follows that this is an act committed within the framework of legitimate political discourse. Therefore, PCO is politically legitimate even if it is not always legal. In other words, the discussion of PCO offers a theoretical distinction between political legitimacy and legality.  相似文献   

19.
The conventional account of American diplomacy in the modern era is marked by a cultural tension between realist and idealist themes symbolized by the statecraft of Theodore Roosevelt and Woodrow Wilson. However, a revisionist account has emerged to challenge and even reverse the conventional account of Roosevelt and Wilson. This poses an intriguing empirical puzzle that is essentially psychological, as it pertains to the belief systems of these two presidents. In order to investigate this puzzle and its implications for U.S. strategic culture, we employ an automated content analysis of the public statements by the two leaders regarding their operational code beliefs about the nature of the political universe and the best approach to effective political action. The results reveal similarities and differences in their belief systems and illustrate how psychological models can provide insights into the psychocultural origins of U.S. diplomacy that remain relevant to the present day.  相似文献   

20.
This paper is a presentation and discussion of Spinoza's view on the knower, or the mind, as an agent. The knower is on his view to be regarded as an active or generative complex cognitive experience. Imagination, reason and intuition are the cognitive principles. On account of their intrinsic relation to the first law of nature, that of selfpreservation, together with the thesis of the mind as constituted by ideas or knowledge, these principles function at the same time as moral principles. Consequently, it makes sense to speak of an individual's moral attitude toward everything be knows. A discussion of imagination, reason and intuition mainly as cognitive principles is followed by some concluding remarks on the cognitive and moral relation between human beings: To know another human being is to know his knowledge. The moral attitude of individuals to each other is a function of their mutual knowledge of knowledge.  相似文献   

设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号