大鼠大脑两半球机能不对称性个体发生的初步探讨——苯异丙胺诱发婴鼠旋转行为的实验研究

断奶前Wistar婴鼠168只,分为0、2、4、6……20日龄共11个日龄组。记录每只动物腹腔注射苯异丙胺(5毫克/公斤)所诱发的旋转行为,以研究大鼠大脑两半球机能不对称性的个体发生。本实验观察到0日龄(出生后0—12小时)婴鼠即可被苯异丙胺诱发低水平的旋转行为,其旋转行为水平随日龄的增长而提高。该实验结果表明大鼠在出生时大脑两半球机能已存在不对称性特征。     

雄性HSF1基因缺陷小鼠的行为改变

为研究HSF1基因缺陷小鼠的行为特征,探索HSF1基因在小鼠行为表现中的作用。选取6~7个月大雄性HSF1基因缺陷小鼠39只及野生型小鼠36只进行情绪性评分、旷场实验、高架十字迷宫实验、简易迷津实验、T-CAT实验、独木桥实验和悬挂实验以观察其情绪性唤醒水平、焦虑水平、探索行为、工作记忆能力和运动能力。结果表明HSF1基因缺陷小鼠的情绪唤醒水平和焦虑水平较低、探索行为减少、T-CAT中转换率较低,提示小鼠的情绪、探索动机和工作记忆受HSF1基因的调控     

6-羟基多巴胺所致旋转行为的动物模型

选用神经毒素(6-OHDA)造成动物大脑黑质纹状体的单侧性损伤,致使动物的大脑两半球机能显示不对称性。致伤后以可卡因诱发动物的旋转行为。 本实验共观察了成年的Holtzman种系雌性大白鼠43只。结果表明,有38例(88.37％)的多巴胺的耗竭率在85一100％,它们的伤情较为理想。但是,3只动物(6.98％)的多巴胺的耗竭率小于60％,2只动物(4.65％)的多巴胺的耗竭率在60—84％。 本文详细地介绍了如何制备和利用旋转仪自动记录动物的旋转行为,以及用高效液相色谱法测定大脑纹状体内多巴胺的含量。     

不同月龄小鼠行为训练与脑突触蛋白的相关性研究

不同年龄动物在各种行为实验中表现出学习记忆能力不同。一般地说,动物进入中年期以后,记忆保持力(retention)随年龄增长而下降。有关衰老性记忆障碍与脑内神经细胞变化的相关性已有大量观察记载,但中、幼年阶段的记忆力差异及其脑内突触机制     

领导者的人格特质和行为方式——企业和学校领导者的比较

本文运用了勒温的民主行为问卷、李克特的人—事行为问卷和Y—G 性格测验量表,调研了140名企业和学校领导者的人格特质、性格类型和行为方式.结果表明:(1)大多数企业领导者具有D 型性格和一般活动性、支配性、社会外向性的人格特质,大多数学校领导者具有C 型性格和客观性、合作性、非抑郁性的人格特质,没有一个领导者具有B 型和E 型性格;(2)具有放任型领导方式的人数最多,具有以人为中心的领导方式的领导者人数最少.     

语言符号与知觉符号表征对外语词汇习得的影响比较：来自行为与脑电的实验证据

通过行为与脑电实验技术,比较外语词汇学习过程中,语言符号与知觉符号表征对词汇记忆编码与再认的影响过程,从而考察语义表征对词汇习得的影响机制。行为结果表明,语言符号与知觉符号表征条件下被试对词汇学习效果的主观判断无显著差异,但后者比前者有更高的词汇再认正确率。脑电结果表明,对于词汇编码阶段,相较语言符号表征,知觉符号表征在编码晚期诱发更正的LPC成分;对于词汇再认阶段,知觉符号表征条件诱发更大N400成分,且脑电时频分析表明该条件下出现更为明显的μ波抑制及θ波功率增强现象。研究结果综合表明,与语言符号表征便捷但非模态化的语义加工相比,知觉符号表征加深了词汇晚期编码的深度,并通过知觉模拟,利用多模态信息提高了词汇的形象化再认,从而推动了再认阶段的语义检索,最终内隐性地提高了词汇学习效果。     

青少年与成年人情绪冲突控制的年龄差异：一项行为和ERP研究（英文）

青春期被喻为“狂风骤雨期”,青少年可能比年幼的儿童和年长的成年人有更大的情绪抑制和控制的需求。情绪抑制控制能力与冒险行为、异常的心理和行为发展有关。本研究采用事件相关电位（ERP）方法探讨青少年与成人之间的情绪冲突控制的差异。31名早期青少年（男生19名;M年龄=12.66岁）和33名成年人（男生16名;M年龄=20.15岁）完成了面孔-词Stroop任务。在该任务中,情绪词叠加在情绪面孔上构成一致和不一致条件,被试被要求判断面孔的效价（面孔任务）或词语的效价（词语任务）。分析两组被试在行为表现和与情绪信息加工相关的ERP成分上的年龄差异。结果表明：（1）青少年在面孔判断任务中存在Stroop效应（一致性条件下的反应时间比不一致条件下的反应时间短）,而对于成年人而言,在面孔和词语判断任务中均发现了Stroop效应;（2）在青少年中,不一致条件诱发的N450波幅显著大于一致条件;（3）N450成分的Stroop效应仅在词语判断任务中出现,而SP成分的Stroop效应仅在面孔判断任务中出现。研究结果提供了神经证据表明,与成人相比,青少年处理情绪冲突的能力较差,这可能与其情绪控制相关的前额叶...     

基于成本最小化信息的社会性意图识别：来自脑电和行为的证据

与已有研究着重考察如何识别客体导向性意图(动作以物理对象为目标, 而不涉及其他人)不同, 本研究对人们如何识别社会性意图(动作以指向社会主体为目标以影响对方的交互行为)进行了探讨。基于两交互主体在整体层面应遵循效用最大化的分析, 提出当A协助B达成目标状态所需要的成本小于B单独实现该目标状态所需要的成本时(简称为成本最小化信息), 其可被识别为具有社会性意图。通过在B面前设置栅栏的方法操纵成本最小化信息, 以指示不同意图类型的脑电μ抑制程度、对不同变化的敏感性(辨别力)为指标, 对该假设进行了检验。结果显示, 相比客体导向性意图的控制条件(即A将目标物苹果放置在石头前), 当A将目标物苹果放置在被栅栏挡住的B前, 其动作可减少B单独获取该苹果的动作成本, 即符合成本最小化条件时, μ的抑制程度更高(实验1), 且对结构改变(某两个动画中充当相同角色的智能体互换)的辨别力更强, 但对角色交换(某个动画中两个智能体的角色交换)的辨别力更弱(实验3a); 而当栅栏不存在时, 虽然A的运动路径与实验1相同, 但A将苹果放置在B前的成本大于B自身获取苹果的成本, 即不符合成本最小化条件, 条件间μ抑制的差异消失(实验2), 且对不同动作模式中变化的辨别相当(实验3b)。鉴于已有研究表明社会性意图所诱发的μ抑制强于客体导向性意图, 且人们对存在社会性意图的两个智能体间的结构改变更容易辨别, 而对角色交换不敏感, 故上述结果揭示, 两个个体的行为是否满足成本最小化影响人们对动作意图的识别, 支持成本最小化信息是社会性意图识别线索的观点。     

LOSS OF SELF AS ETHICAL LIMIT

This Comment argues that Stephen Bush's critique of Georges Bataille's meditative practice fails to recognize how the disruption of the self, and the challenge to goal‐oriented activity that comprise the heart of that practice, serve as an ethical limit that protects against sadistic and violent engagement with the world. The ethical disposition fostered by Bataille's practice is a dissolution of the self.     

AN INVESTIGATION OF COMPLIANCE-GAINING AS POLITENESS

This study considers an alternative perspective on the compliance-gaining phenomenon, specifically the theory of politeness articulated by Brown and Levinson (1978). They posit that all interaction is characterized by concern over the other person's autonomy needs and his or her desire to be liked, manifested in message behavior that addresses these needs (i.e., politeness). Brown and Levinson's typology of politeness strategies was translated into 32 items to which 155 respondents indicated likelihood of use and perceived politeness. Respondents assessed the items while imagining themselves in one of eight hypothetical scenarios created to manipulate the three situational factors posited as significant by Brown and Levinson: relationship distance, relationship power, and the magnitude of the request. A factor analysis reduced the 32 tactics to four underlying factors, which in turn served as one variable set for a canonical correlation whose second variable set was the situational factors and the agent's gender. Results indicated that females and persons in close relationships use more polite tactics than males and persons in more distant relationships. Secondarily, results also indicated that persons with power use less politeness than less powerful persons.     

PHILOSOPHY AS EMPIRICAL EXPLORATION OF LIVING

This essay describes an approach to designing a course in philosophy as a way of life (PWOL) around a set of immersive “spiritual exercises” through which students might examine their desires, engaging students in a process of testing their own experience against philosophical theories and theories against their own experience. These are used to tie together the units of a course covering classical Western and Eastern philosophical traditions, and to supplement traditional philosophical analysis of texts and arguments with ways of exploring what it might be like to live as a Platonist, Stoic, or Confucian. The essay details several exercises, engages perspectives on PWOL from Pierre Hadot and John Cooper, and addresses the question of how to assess immersive exercises.     

PREDICTIVE EFFICIENCY AS A FUNCTION OF AMOUNT OF INFORMATION

The effect of changing the amount of information on judges' predictive efficiency in a clinical prediction task was studied. Thirty judges predicted 30 students' average achievement scores on the basis of different amount of test data. One group of judges had information about the intercorrelations among the tests and the ecologkal validity of the tests. Another group of judges had only informahion about which tests were used. The predictive efficiency was not a monotonically increasing function of amount of test data. The most marked result was that the relative predictive efficiency decreased from four to six tests in both groups.