转化医学与肿瘤诊治

转化医学是促进基础研究成果向临床应用转化和根据临床医学的需求从事应用基础研究的桥梁。本文以转化医学在肿瘤防治研究的实例,分析转化医学的意义,以期为使大家重视转化医学,提高肿瘤诊治水平。     

转化医学的哲学认识

转化医学是将基础研究成果转化为实际应用的理念和方法,属于认识范畴,是医学实践发展的产物,其内涵随着医学实践的发展而发展;转化医学是对基础医学和临床医学之间分割局面的否定之否定;转化医学的具体实施过程体现了认识事物的一般规律,它的研究主体、客体和方法属于复杂系统,所以须以系统理论为指导才能得以顺利实现。     

转化医学体系下的学科服务模式探讨

转化医学的出现极大地推动了医学研究模式的变革,同时转化医学模式对服务于医学研究的图书馆也带来了机遇和挑战,通过对转化医学实现路径的分析,发掘出转化医学研究的实际需求,结合目前学科馆员服务面临的困境,从中寻找出适应转化医学模式的学科服务模式,从而为开展进一步的工作打下良好的基础.     

大数据时代背景下的医学思考*--转化医学新趋势前瞻

作为21世纪最具活力的医学发展模式,转化医学为基础和临床构建了交流沟通的高效平台,当前正朝着多学科、多领域、多系统的方向迈进。随着信息技术与生命科学的交叉融合,生物医学已经迈入大数据时代。大数据既保证了医学实践的深度,有深度才能洞悉本质;又保证了医学实践的高度,有高度才能总揽全局。因此,大数据的出现为深陷还原论泥潭的现代医学提供了有效的解决途径。大数据浪潮对医学基础研究和医疗实践的深远影响,必将为转化医学发展带来新的发展机遇。     

转化医学应用现状及其困境分析

转化医学的理念已经蓬勃发展起来,但对大多数处于临床一线的医生而言,却产生了较多困惑:基础医学与临床医学之间仍相互脱节,许多先进的基础医学研究难以为临床实践所用,基础医学的先进成果向临床的转化难以实现.因此,对于转化医学理念的提出,应有所反思,使转化医学的价值得以充分地发挥.     

我国转化医学发展现状的思考

转化医学在当今世界发展迅速,虽然在我国起步较晚,但取得了巨大的成就,建立了许多转化医学研究机构,积极开展合作交流,但不可避免地存在一些问题,诸如创新能力不足、顶层设计不够和人才缺乏等,为此提出相应对策和未来发展的前景,同时指出转化医学在我国不仅是学术问题,而且是社会问题.     

转化医学在外科腹腔镜训练中的应用

转化医学是国际医学领域近年来提出的一个新的理念,旨在基础医学与临床医学紧密结合,是一个与外科腹腔镜基础训练成果转化为临床腹腔镜手术的密切相关的概念,其核心理念在于“转化”,本文综述转化医学在国内外的发展,以及其理念在外科腹腔镜训练中的应用,以促进转化医学及外科腹腔镜训练在国内的发展.     

我国当代医学伦理话语体系建构初探

当前我国医学伦理某些基本话语使用存在问题,甚至已成严重的综合征。医学伦理话语体系是医德思想的载体,是医德生活和医学伦理学表达所必需的基本材料,必须精雕细刻。建构医学伦理话语体系必须直面现实话语问题,从语言哲学、医德生活现实、社会转型、医学伦理学使命担当等方面追寻病因,对症下药。目前,医学伦理话语体系构建的要务是亟需建构共识,着力解决医学伦理话语言与行的相互转化的实际运转机制问题。     

医学科研的可重复性与转化医学——从生命的复杂性谈起

转化医学为基础研究成果向临床转化提供了有效途径.转化医学的效率受多种因素影响,其中研究成果的可靠性是其基石.当前,简单思维模式指导下的基础研究往往忽视了生命现象的复杂性本质,导致基础研究的结果在一定程度上并不完全可靠,从而严重影响了转化医学的发展,这提示对于生命现象这类复杂系统科学研究需要复杂性思维.     

转化医学的伦理审查与管理实践

伦理审查委员会应以转化医学发展为契机,做好以下几方面工作:引入科学审查委员会审查机制,克服科学审查的不足;以新的标准建设伦理委员会,克服伦理自身的不足;引入伦理与行政部门沟通协作机制,克服持续监管的不足;拓展伦理教育咨询,克服研究者伦理方面的认识不足。伦理审查的规范化运行有利于保证患者利益的最大化。     

Together – apart: in touch in a time of separation

This paper explores the experience of working as a Jungian analyst through the various phases of the global COVID-19 pandemic, examining the importance of the physical containing space alongside the analyst’s internal mind and how technology can both help and hinder understanding. A number of clinical vignettes illustrate the challenge of communicating over a distance, paying particular attention to the way countertransference phenomena can become re-attuned. Reference is made to mythology and symbols of hope, and consideration given to the meaning and purpose of the pandemic.     

The Possibility of Meaning in Human Evolution

Science undermines the certitude of non-naturalistic answers to the question of whether human life has meaning. I explore whether evolution can provide a naturalistic basis for existential meaning. Using the work of philosopher Daniel Dennett and scientist Ursula Goodenough, I argue that evolution is the locus of the possibility of meaning because it has produced intentionality, the matrix of consciousness. I conclude that the question of the meaning of human life is an existentialist one: existential meaning is a product of the individual and collective tasks human beings undertake.     

Phenotypic plasticity and archetype: a response to common objections to the biological theory of archetype and instinct

Since Jung’s death in 1961, scholars have attempted to integrate growing biological science data into Jungian concepts such as the collective unconscious, instincts and the archetypes. This enterprise has been challenging due to persistent false dichotomies of gene and environment occasionally arising. Recent works by Roesler (2022a, 2022b) for example, have raised objections to the biological theory of archetypes, but the objections are plagued by such dichotomies. The concept of phenotypic plasticity, however, helps to both avoid this problem as well as bridge the gap between competing theories into a more integrated model with solid biological foundations.     

When is it time to stop? When good enough becomes bad enough

This article draws on Winnicott’s concept of the good enough mother to discuss how to know whether a therapeutic situation is good enough to continue or bad enough to end. This dilemma is explored in terms of clinical syndromes, such as anorexia and pathological gambling, but focuses mainly on analyst-initiated endings, which are termed the ‘Casablanca dilemma’, based on an amplification of the ending of the film Casablanca. The author goes on to discuss such one-sided endings, drawing on interviews with 40 analysts and therapists about their clinical experience. A typology of bad enough endings is presented. The psychological differences between a good enough analysis as opposed to a bad enough one are explored through the ideas of Winnicott and Neumann.     

Kann Es Ein Argument Für Den Skeptizismus Geben? Das Epistemische Problem Der Irrtumsmöglichkeit

Summary  Is there any argument for scepticism? The epistemic problem of the possibility of error. Arguments for scepticism rest on the assumption that knowledge claims are fallible. For this reason the concept of knowledge appears to be questionable. Since it is necessary to distinguish doubts from possible doubts, the arguments for scepticism appear to be unconvincing. If we take it into account that we know something that is immune to doubt, we should draw the conclusion that, contrary to scepticism, knowledge claims have to be compatible with being fallible. Thus any knowledge claim is capable of being doubted.     

The transcendent function in Spitteler’s Prometheus and Epimetheus

In August 2020, John Beebe and Steve Myers met via Zoom to discuss their differing interpretations of psychological typology and the different sources within Jung’s writings that influenced their books: Integrity in Depth: Energies and Patterns in Psychological Type (Beebe), and Myers-Briggs Typology vs Jungian Individuation (Myers). The discussion centred on Spitteler’s epic poem Prometheus und Epimetheus, which forms the basis of chapter V of Psychological Types. This is both the largest chapter and one of two chapters that Jung highlighted in the Argentine foreword as containing the essence of the book. Jung’s book is primarily about the transformation of personality rather than the categorization of people. Although it contains a critical psychology that deconstructs the nature of consciousness, that is only one half of the book and a stepping-stone to the other half, which is the reconciliation of opposites with particular emphasis on the relation of consciousness and the unconscious. Jung assumed that readers were already familiar with Prometheus und Epimetheus, an understanding of which sheds light on the nature of the transformation that Jung described – the development of a new attitude towards attitude itself.     

Chapter 6: Biblical Foundations for a Practical Theology of Aging

SUMMARY

This article reviews Biblical sources pertaining to the elderly, particularly the frail elderly. Founded on these sources, implications for elderly with Alzheimer's Disease and other forms of dementia are addressed through a personal perspective informed by writings of Christian mystics.     

Seeing in the Dark: A View into Dissociation and Healing

In this paper, I will explore the role of art-making, the experience of trauma and dissociation, and the process of working with self-states from an analytic and creative frame. Relevant literature on dissociation, trauma, and the use of art will be discussed. A case involving my work with an adolescent girl who had experienced sexual abuse from a family member will be shared, with an emphasis on the meaningful role images played during the therapeutic process. Both Jungian and psychoanalytic models of conceptualizing and working with dissociation are included, following Donald Kalsched’s (2013) recommendation for a “binocular stance” to treatment, including both a focus on the inner, intrapsychic world and the interpersonal, relational realm, and how art images both illuminated and expressed these realms. Within the therapeutic process, art images allowed the therapist a view into the client’s unconscious process, and created a meeting ground for dissociative barriers to be gradually seen, felt and known, by both therapist and client. The experience of dissociation, in images and in session, provided a reference point for myself and my client, Taylor, to develop a shared understanding and a framework for growth.