重大交通肇事司机睡眠打鼾情况调查分析

调查重大肇事司机打鼾的患病率,打鼾和ESS评分的关系以及打鼾对交通事故的影响.对350例肇事司机进行现况问卷调查.结果重大肇事司机的打鼾患病率为44.9％,打鼾司机ESS评分≥9分者明显高于无打鼾司机(x2=13.64,P＜0.01),打鼾所致交通事故发生率和其他常见原因接近,肇事司机对打鼾的认知程度低,需引起临床医生和行政管理部门的重视.     

中年人睡眠相关行为与高血压关系的病例对照研究

为探讨中年人睡眠相关行为与高血压发病风险之间的关系。本研究采用1：1匹配的病例对照研究法;资料收集方法采用问卷调查法;资料处理分析采用t检验及多元条件Logistic回归模型分析法。结果显示中年人病例组与对照组睡眠质量存在显著性差异（t=6．19,P〈0．05）。（1）睡眠相关行为（每日睡眠不足、夜间睡眠不足、睡眠时点延迟、睡眠质量差、入睡困难、每周入睡困难次数增加及打鼾等因素）多元条件Logistic回归模型的OR值和95％CI分别为[（OR=5．07,95％CI：3．12～8．21）;（OR=5．57,95％CI：3．43～9．04）;（OR=2．27,95％CI：1．49～3．47）;（OR=2．17,95％CI：1．60～2．94）;（OR=3．36,95％CI：1．47～7．69）;（OR=1．55,95％CI：1．08～2．24）;（OR=2．69,95％CI：1．86～3．88）]。（2）适当午睡为（OR=0．85,95％CI：0．74～0．98）。（3）早起与否（OR=1．40,95％CI：0．87～2．20）。因此（1）中年人睡眠相关行为与高血压发病密切相关,每日睡眠不足、夜间睡眠不足、睡眠时点延迟、睡眠质量差、入睡困难、每周入睡困难次数增加及打鼾等因素可能为高血压发病的危险因素;（2）中年人适当午睡可能是高血压发病的保护性因素;（3）是否早起与高血压发病关系尚不清晰。     

重大交通肇事司机睡眠打鼾情况调查分析

调查重大肇事司机打鼾的患病率,打鼾和ESS评分的关系以及打鼾对交通事故的影响。对350例肇事司机进行现况问卷调查。结果重大肇事司机的打鼾患病率为44．9％,打鼾司机ESS评分≥9分者明显高于无打鼾司机（X^2=13．64,P〈0．01）,打鼾所致交通事故发生率和其他常见原因接近,肇事司机对打鼾的认知程度低,需引起临床医...     

生长抑素与其他药物治疗肝硬化食管静脉曲张破裂出血比较的Meta分析

探讨生长抑素治疗肝硬化食管静脉曲张破裂出血的安全性和有效性。对MEDLINE和CNKI中国期刊全文数据库中,2007年4月20日之前已发表的关于生长抑素治疗肝硬化食管静脉曲张破裂出血的随机对照临床试验进行Mere分析。与生长抑素相比,血管加压素副作用发生率高[OR=27．62,95％CI（8．30,91．90）],垂体后叶素止血率低[OR=0．27,95％CI（0．19,0．36）],副作用发生率高[OR=8．87,95％CI（5．74,13．72）],病死率高[OR=5．37,95％CI（2．73,10．57）]。生长抑素是一种安全有效的治疗肝硬化食管静脉曲张破裂出血的药物。     

非那雄胺与前列腺癌发病率及病理分级的Meta分析

应用Meta分析法对有关非那雄胺与前列腺癌发病率及病理分级关系的研究进行综合评价。符合标准的8篇文献进行Meta分析,计算比值比（OR）、95％可信区间（95％C1）。结果8篇文献,无异质性（Q=6．26,P=0．51）,非那雄胺治疗组降低前列腺癌发病风险高于对照组,合并OR值为0．68（95％CI：0．65～O．71...     

非那雄胺与前列腺癌发病率及病理分级的Meta分析

应用Meta分析法对有关非那雄胺与前列腺癌发病率及病理分级关系的研究进行综合评价.符合标准的8篇文献进行Meta分析,计算比值比(OR),95%可信区间(95%C1).结果8篇文献,无异质性(Q=6.26,P=0.51),非那雄胺治疗组降低前列腺癌发病风险高于对照组,合并OR值为0.68(95%CI:0.65～0.71,Z=17.16,P=0.00).Egge:检验提示无发表偏倚(P=O.21).对前列腺癌病理分级进行分组,非那雄胺治疗组前高于对照组.合并OR值为2.16(95%CI:1.97～2.36,Z=16.93,P=0.00).非那雄胺治疗前列腺增生能降低前列腺癌的发病风险,也能使发生的前列腺癌的病理级别增高.     

隐匿性高血压与脑卒中的相关性分析

探讨隐匿性高血压与脑卒中的相关性及其临床意义。纳入2017年1月～2018年6月就诊于郑州大学第一附属医院心内科行诊室血压及24小时动态血压监测的420例住院患者为研究对象,根据血压监测结果将其分为高血压组(HT组140例)、隐匿性高血压组(MH组140例)、正常对照组(NC组140例),对三组的临床资料与临床指标进行统计学分析,采用Logistic回归分析脑卒中的危险因素。与NC组比较,HT组及MH组糖尿病史[27(18.29%)、24(17.14%)比8(5.71%),均P0.05]、同型半胱氨酸(Hcy)水平[(15.03±6.77)μmol/L、(15.00±6.06)μmol/L比(13.64±5.02)μmol/L,均P0.05]、脑卒中人数[37(26.43%)、38(27.14%)比22(15.71%),均P0.05]均较高,差异均有统计学意义,HT组与MH组相比这三项指标相近,差异均无统计学意义(P0.05);以正常对照组为参照行多元Logistic回归分析,结果显示隐匿性高血压(OR=1.697,95%CI:0.901～3.129,P=0.013)、糖尿病(OR=2.327,95%CI:1.013～5.347,P=0.017)及同型半胱氨酸(OR=1.083,95%CI:1.030～1.138,P=0.002)为脑卒中的独立危险因素。隐匿性高血压患者发生脑卒中的风险增加。     

修复基因XRCC4启动子-1394多态性与胃癌关联性的研究

XRCC4基因是一个非常重要的DNA损伤修复基因,在维持基因组的完整性与稳定性方面起着重要的作用,有效预防肿瘤的发生。本研究选取了210例胃癌患者及254例性别、年龄相匹配的正常对照者进行研究,采用限制性片段长度多态性方法,明确胃癌患者及正常对照者基因型。XRCC4基因启动子-1394多态性两组间有显著差异。XRCC4基因启动子-1394多态性的G等位基因频率,胃癌组明显高于正常对照组（OR=2．35,95％CI=1．24～4．46,P=0．007）;基因型频率胃癌组与正常对照组有显著差异（P=0．008）：携带基因型TG的个体比TT的个体罹患胃癌的风险提高了2．46倍（95％CI=1．27—4．76）。总之,XRCC4基因启动子-1394位点的G等位基因在胃癌的发生过程中起着至关重要的作用。     

2010~2020中国内地小学生心理健康问题检出率的元分析

我国小学生心理健康问题的检出率莫衷一是, 为整合调查结果并分析其原因, 对2010~2020年来检索到的相关研究进行了元分析。结果显示：(1)小学生心理健康问题的检出率由高到低依次是睡眠问题(25.2%, 95% CI = [0.16, 0.37])、抑郁(14.6%, 95% CI = [0.12, 0.18])、焦虑(12.3%, 95% CI = [0.06, 0.23])、攻击行为(4.1%, 95% CI = [0.02, 0.10])、退缩(3.8%, 95% CI = [0.02, 0.06])、违纪行为(3.7%, 95% CI = [0.02, 0.07])、躯体化(3.6%, 95% CI = [0.02, 0.07])。(2)测量工具、检出标准、检出时间是导致小学生心理健康问题检出率不一致的关键因素。总体而言, 我国小学生除了睡眠问题、抑郁和焦虑检出率偏高外, 整体心理健康状况尚可。未来应开发适合中国小学生的心理健康状况测评工具及检出标准, 为心理健康问题的预防和精准干预提供支持。     

生长抑素与其他药物治疗肝硬化食管静脉曲张破裂出血比较的Meta分析

探讨生长抑素治疗肝硬化食管静脉曲张破裂出血的安全性和有效性.对MEDLINE和CNKI中国期刊全文数据库中,2007年4月20日之前已发表的关于生长抑素治疗肝硬化食管静脉曲张破裂出血的随机对照临床试验进行Meta分析.与生长抑素相比,血管加压素副作用发生率高[OR=27.62,95%CI(8.30,91.90)],垂体后叶素止血率低[OR=0.27,95%CI(0.19,0.36)],副作用发生率高[OR=8.87,95%CI(5.74,13.72)],病死率高[OR=5.37,95%CI(2.73,10.57)].生长抑素是一种安全有效的治疗肝硬化食管静脉曲张破裂出血的药物.     

Language,politics and dreams: the challenges of building resilience in refugees

This paper describes a case study of a 60-year-old Peruvian refugee in some detail, focusing on the importance of building emotional resilience in a patient in Spanish in order to create a space for learning the English language – the patient did not speak English after 20 years of living in Britain. The work was carried out with an interpreter and some of the literature on working with interpreters is referred to. The paper also briefly outlines the refugee journey in broad terms, which is a journey from the culturally known to the culturally unknown. The question of how well the literature on resilience, which sits firmly within a Western developmental perspective, can be applied to refugees, most of whom come from group and family-based cultures dominated by ideas of honour and shame, is discussed. The paper also touches on the importance of the receiving country enabling or not, as the case may be, a transitional space for refugees who have lost their home and are seeking to find a safe haven in a strange culture.     

Together – apart: in touch in a time of separation

This paper explores the experience of working as a Jungian analyst through the various phases of the global COVID-19 pandemic, examining the importance of the physical containing space alongside the analyst’s internal mind and how technology can both help and hinder understanding. A number of clinical vignettes illustrate the challenge of communicating over a distance, paying particular attention to the way countertransference phenomena can become re-attuned. Reference is made to mythology and symbols of hope, and consideration given to the meaning and purpose of the pandemic.     

Phenotypic plasticity and archetype: a response to common objections to the biological theory of archetype and instinct

Since Jung’s death in 1961, scholars have attempted to integrate growing biological science data into Jungian concepts such as the collective unconscious, instincts and the archetypes. This enterprise has been challenging due to persistent false dichotomies of gene and environment occasionally arising. Recent works by Roesler (2022a, 2022b) for example, have raised objections to the biological theory of archetypes, but the objections are plagued by such dichotomies. The concept of phenotypic plasticity, however, helps to both avoid this problem as well as bridge the gap between competing theories into a more integrated model with solid biological foundations.     

The Possibility of Meaning in Human Evolution

Science undermines the certitude of non-naturalistic answers to the question of whether human life has meaning. I explore whether evolution can provide a naturalistic basis for existential meaning. Using the work of philosopher Daniel Dennett and scientist Ursula Goodenough, I argue that evolution is the locus of the possibility of meaning because it has produced intentionality, the matrix of consciousness. I conclude that the question of the meaning of human life is an existentialist one: existential meaning is a product of the individual and collective tasks human beings undertake.     

When is it time to stop? When good enough becomes bad enough

This article draws on Winnicott’s concept of the good enough mother to discuss how to know whether a therapeutic situation is good enough to continue or bad enough to end. This dilemma is explored in terms of clinical syndromes, such as anorexia and pathological gambling, but focuses mainly on analyst-initiated endings, which are termed the ‘Casablanca dilemma’, based on an amplification of the ending of the film Casablanca. The author goes on to discuss such one-sided endings, drawing on interviews with 40 analysts and therapists about their clinical experience. A typology of bad enough endings is presented. The psychological differences between a good enough analysis as opposed to a bad enough one are explored through the ideas of Winnicott and Neumann.     

Seeing in the Dark: A View into Dissociation and Healing

In this paper, I will explore the role of art-making, the experience of trauma and dissociation, and the process of working with self-states from an analytic and creative frame. Relevant literature on dissociation, trauma, and the use of art will be discussed. A case involving my work with an adolescent girl who had experienced sexual abuse from a family member will be shared, with an emphasis on the meaningful role images played during the therapeutic process. Both Jungian and psychoanalytic models of conceptualizing and working with dissociation are included, following Donald Kalsched’s (2013) recommendation for a “binocular stance” to treatment, including both a focus on the inner, intrapsychic world and the interpersonal, relational realm, and how art images both illuminated and expressed these realms. Within the therapeutic process, art images allowed the therapist a view into the client’s unconscious process, and created a meeting ground for dissociative barriers to be gradually seen, felt and known, by both therapist and client. The experience of dissociation, in images and in session, provided a reference point for myself and my client, Taylor, to develop a shared understanding and a framework for growth.     

Order,disorder, and the absolute: An experiment in dialogue

The first section of this dialogue is excerpted from an edited conversation between Sean Kelly and the late David Bohm, and focuses on the concepts of order, disorder, and the Absolute. The second section explores these concepts in greater depth, with Bohm maintaining the impossibility of absolute knowledge and the fundamental unintelligibility of the concept of disorder, preferring instead to speak of “orders of infinite degree” which emerge out of an “unknown ground.” Kelly responds by proposing the concept of “absolute knowing” as the cognitive process within which the concepts of order and disorder, the known and the Unknown are seen as dialectically related moments of the Absolute as complex whole. The third section is Edgar Morin's response to the preceding dialogue. He begins by outlining his views on the nature and limits of rationality, maintaining, with Bohm, the superiority of the “negative modality” of speaking about “being” or “reality.” In the second part, however, he proposes the notion of nature as “chaosmos,” which he understands as a creative “dialogic” of order, disorder, and organization.     

Countering Cultural Metaphors of Aging

SUMMARY

This article examines three clusters of metaphors or cultural images of aging which function to marginalize older adults: metaphors which focus on aging as physical decline, on aging as aesthetic distance from youth, and on aging as failure of productivity. It then sketches out two ways to counter the marginalizing power of these cultural images of aging, to shape new metaphors or images of aging within a community of meaning, and to help make new sense of growing old, namely the formation of face-to-face groups of older adults and the creation of rituals in worship which name publicly the realities and experiences of aging.