Integrating Systems of Care in California for Youth with Severe Emotional Disturbance IV: Educational Attendance and Achievement

Empirical results are presented from school-based interventions in three California counties that are pioneering participants in a carefully evaluated effort to create an innovative system of care for youth with severe emotional disturbance. Data are presented about the educational attendance and achievement of youth enrolled in clinical and academic programs designed to provide collaborative mental health and education services. Attendance levels were uniformly high. The youth were below expected grade level as measured by standardized tests at program admission. Across programs, two counties demonstrated grade level increases of one year or more for one year in school on all subscales of established measures of educational achievement. The third county demonstrated increases of slightly less than one year on two of three subscales of the educational achievement measures. These results are the first from a multisite demonstration of integrated education and mental health programs embedded within a broader system of care for youth. The findings, combined with those from our prior studies, illustrate that is possible to reduce and control placements in restrictive levels of care while improving the academic performance of a vast majority of the youth enrolled in specialized programs within the care systems.     

BRCA1 testing and informed consent in a woman with mild retardation

Cancer predisposition testing can pose complex genetic counseling issues. This casereport discusses whether it is appropriate to provide BRCA1 testing to a woman withlimited intellectual capacity and documented psychological distress. This case is one ofseveral cancer counseling cases presented to our Genetic Counseling Supervision Groupover the past three and a half years. The Supervision Group provided valuable feedback and supportto proceed with this challenging case.     

An Extension of Multiple Correspondence Analysis for Identifying Heterogeneous Subgroups of Respondents

An extension of multiple correspondence analysis is proposed that takes into account cluster-level heterogeneity in respondents’ preferences/choices. The method involves combining multiple correspondence analysis and k-means in a unified framework. The former is used for uncovering a low-dimensional space of multivariate categorical variables while the latter is used for identifying relatively homogeneous clusters of respondents. The proposed method offers an integrated graphical display that provides information on cluster-based structures inherent in multivariate categorical data as well as the interdependencies among the data. An empirical application is presented which demonstrates the usefulness of the proposed method and how it compares to several extant approaches. The work reported in this paper was supported by Grant 290439 and Grant A6394 from the Natural Sciences and Engineering Research Council of Canada to the first and third authors, respectively. We wish to thank Ulf B?ckenholt, Paul Green, and Marc Tomiuk for their insightful comments on an earlier version of this paper. We also wish to thank Byunghwa Yang for generously providing us with his data.     

关于高校的实验与实践教学：基于教育心理学理论的思考

对于高校教育,运算学习方法多指实验、实践和学生科研活动,学生通过从事的实验、实践和科研活动来实现陈述性知识向程序性知识的转化,学习评价应着重考核学生对知识的理解和运用所学知识去解决问题的能力。本文阐述了突出实验／实践训练的高校教学设计的设想,并强调了应将各种教学实验类型有机地组合,给予学生先进、实用的实验技术的训练,以及在实验／实践教学中运用交互式的教学方法。     

Length, formats, neighbours, hemispheres, and the processing of words presented laterally or at fixation

It has long been known that the number of letters in a word has more of an effect on recognition speed and accuracy in the left visual field (LVF) than in the right visual field (RVF) provided that the word is presented in a standard, horizontal format. After considering the basis of the length by visual field interaction two further differences between the visual fields/hemispheres are discussed: (a) the greater impact of format distortion (including case alternation) in the RVF than in the LVF and (b) the greater facilitation of lexical decision by orthographic neighbourhood size (N) in the LVF than in the RVF. In the context of split fovea accounts of word recognition, evidence is summarised which indicates that the processing of words presented at fixation is affected by the number of letters to the left of fixation but not by the number of letters to the right and by the number of orthographic neighbours activated by letters to the left of fixation but not by the number of orthographic neighbours activated by letters to the right of fixation. A model of word recognition is presented which incorporates the notion that the left hemisphere has sole access to a mode of word recognition that involves parallel access from letter forms to the visual input lexicon, is disrupted by format distortion, and does not employ top-down support of the letter level by the word level.     

Improving the driving practices of pizza deliverers: Response generalization and moderating effects of driving history

A practical intervention program, targeting the safety belt use of pizza deliverers at two stores, increased significantly the use of both safety belts (143% above baseline) and turn signals (25% above baseline). Control subjects (i.e., pizza deliverers at a third no-intervention store and patrons driving to the pizza stores) showed no changes in belt or turn signal use over the course of 7-month study. The intervention program was staggered across two pizza stores and consisted of a group meeting wherein employees discussed the value of safety belts, received feedback regarding their low safety belt use, offered suggestions for increasing their belt use, and made a personal commitment to buckle up by signing buckle-up promise cards. Subsequently, employee-designed buckle-up reminder signs were placed in the pizza stores. By linking license plate numbers to individual driving records, we examined certain aspects of driving history as moderators of pre- and postintervention belt use. Although baseline belt use was significantly lower for drivers with one or more driving demerits or accidents in the previous 5 years, after the intervention these risk groups increased their belt use significantly and at the same rate as drivers with no demerits or accidents. Whereas baseline belt use was similar for younger (under 25) and older (25 or older) drivers, younger drivers were markedly more influenced by the intervention than were older drivers. Individual variation in belt use during baseline, intervention, and follow-up phases indicated that some drivers require more effective and costly intervention programs to motivate their safe driving practices.     

Assessing the Predictive Accuracy of hMLH1 and hMSH2 Mutation Probability Models

Hereditary nonpolyposis colorectal cancer (HNPCC) is characterized by a susceptibility to colorectal and extra-colonic cancers. Several guidelines exist for the identification of families suspected of having HNPCC, however these guidelines lack adequate sensitivity and specificity. In an attempt to improve accuracy for the detection of individuals with HNPCC, the Wijnen pre-test probability model (1998) and Myriad Genetics Laboratory prevalence table (2004) were developed. Here we evaluate the Wijnen model and Myriad table at predicting the presence of a mutation in individuals undergoing genetic testing for HNPCC. Forty-nine patients who had undergone genetic testing for germline mutations in hMLH1 and/or hMSH2 were part of our analysis. Our results revealed that the revised Bethesda guidelines performed with the highest sensitivity for germline mutations (94.4%), however the specificity was low (12.9%). Using a 10.0% mutation probability threshold, the Wijnen model and Myriad table had sensitivities of 55.6 and 60.0%, respectively and specificities of 54.8 and 23.8%, respectively. The Wijnen model and Myriad table were poor predictors of mutation prevalence, which is shown by the areas underneath their corresponding receiver operator characteristic curves (0.616 and 0.400, respectively). The results of this study demonsrate that neither the Wijnen model nor the Myriad table are sensitive or specific enough to be used as the only indication when to offer genetic testing for HNPCC.     

认知神经和神经心理角度的多重类别学习系统

归类是一项非常重要的认知技能,近十多年来归类的研究尤其关注类别学习的多重系统问题.本文回顾了近年来国外对类别学习的认知神经和神经心理研究,结果表明不同的类别学习任务下的学习机制和所依赖的神经生理基础是不同的,支持类别学习的多系统理论.     

老庄哲学与上博竹书《恒先》

The bamboo slip essay Hengxian 恒先is historically valuable because it serves to further the ontological understanding and comprehension of issues related to the existence of the universe from the perspective of Laozi’s Daoist thought. Hengxian explores important propositions such as how “Qi originated and activated itself” and “they came out of the same source but differed in nature” from several aspects. The idea that “Hengxian is ‘being’ without any definiteness” responds to the issue of the relationship of difference and identity of all things in the world, and thus examines the interdependent relationships between subjects and objects. It proposes that humans can further understand the existence of the universe through cognitive activities and practices such as “analysis and comparison” in which objective realities are checked. The issues discussed in Hengxian are consistent with Laozi’s Dao de jing, the works of Zhuangzi, Huangdi sijing 黄帝四经 (The Four Classics from the Emperor Yellow) and other Daoist works, and deserve significant attention. Translated by Huang Deyuan from Daojia wenhua yanjiu 道家文化研究 (Research of Daoist Culture), 2007, (22): 539–563     

Fruits of Health; Roots of Despair: William James, Medical Materialism and the Evaluation of Religious Experience

In The Varieties of Religious Experience, William James introduces the term “medical materialism” to describe the fallacious attempt by some scientists to argue against the value of spiritual ideas. Two literary case studies will be considered for purposes of better understanding James’ idea. What’s more, it will be shown that, in addition to James’ three criteria for the appropriate evaluation of religious experience, there is another factor not made explicit, namely that of hopefulness. This factor serves to distinguish ordinary from pathological morbid-mindedness, the latter of which has no religious significance.Tadd Ruetenik teaches philosophy at Penn State Altoona. He received his Ph.D. from the English and Philosophy program at Purdue University. Correspondence to Tadd Ruetenik, tlr18@psu.edu.     

Subregion-specific dendritic spine abnormalities in the hippocampus of Fmr1 KO mice

Fragile X syndrome (FXS) is the most common inherited form of mental retardation and is caused by the lack of fragile X mental retardation protein (FMRP). In the brain, spine abnormalities have been reported in both patients with FXS and Fmr1 knockout mice. This altered spine morphology has been linked to disturbed synaptic transmission related to altered signaling in the excitatory metabotropic glutamate receptor 5 (mGluR5) pathway. We investigated hippocampal protrusion morphology in adult Fmr1 knockout mice. Our results show a hippocampal CA1-specific altered protrusion phenotype, which was absent in the CA3 region of the hippocampus. This suggests a subregion-specific function of FMRP in synaptic plasticity in the brain.     

Quintilian and the Pedagogy of Argument

Originating in the Sophistic pedagogy of Protagoras and reflecting the sceptical practice of the New Academy, Quintilian's rhetorical pedagogy places a special emphasis on the juxtaposition of multiple, competing claims. This inherently dialogical approach to argumentation is referred to here as controversia and is on full display in Quintilian's own argumentative practice. More important to this paper, however, is the role of controversia as an organizing principle for Quintilian's rhetorical curriculum. In particular, Quintilian introduces the protocols of controversia through a series of progressively more complex exercises in imitation, role-playing, and declamation (now referred to as situational games). All of these exercises are open for adaptation by contemporary teachers who would promote a dialogical approach to argument, i.e. argument with its methods of inquiry, invention, and judgment based on direct interaction with opposing parties.     

Open questions related to the problem of Birkhoff and Maltsev

The Birkhoff-Maltsev problem asks for a characterization of those lattices each of which is isomorphic to the lattice L(K) of all subquasivarieties for some quasivariety K of algebraic systems. The current status of this problem, which is still open, is discussed. Various unsolved questions that are related to the Birkhoff-Maltsev problem are also considered, including ones that stem from the theory of propositional logics.Special issue of Studia Logica: Algebraic Theory of Quasivarieties Presented by Ryszard Wójcicki     

The ontology of intentionality I: the dependence ontological account of order: mediate and immediate moments and pieces of dependent and independent objects

This is the first of three essays which use Edmund Husserl's dependence ontology to formulate a non-Diodorean and non-Kantian temporal semantics for two-valued, first-order predicate modal languages suitable for expressing ontologies of experience (like physics and cognitive science). This essay's primary desideratum is to formulate an adequate dependence-ontological account of order. To do so it uses primitive (proper) part and (weak) foundation relations to formulate seven axioms and 28 definitions as a basis for Husserl's dependence ontological theory of relating moments. The essay distinguishes between dependence v. independence, pieces v. moments, mediate v. immediate pieces and moments, maximal v. non-maximal pieces, founded v. unfounded qualities, integrative v. disintegrative dependence, and defines the concepts of the completion of an object, the adumbrational equivalence relation of objects, moments of unity which unify objects, and relating moments which relate objects. The eight theorems [CUT90]-[CUT97] show that relating moments of unity provide an adequate account of order in terms of primitive (proper) part and (weak) foundation relations.     

Mirror neurons and the phenomenology of intersubjectivity

The neurological discovery of mirror neurons is of eminent importance for the phenomenological theory of intersubjectivity. G. Rizzolatti and V. Gallese found in experiments with primates that a set of neurons in the premotor cortex represents the visually registered movements of another animal. The activity of these mirror neurons presents exactly the same pattern of activity as appears in the movement of one's own body. These findings may be extended to other cognitive and emotive functions in humans. I show how these neurological findings might be “translated” phenomenologically into our own experienced sensations, feelings and volitions.     

"以生言性"的传统与孟子性善论

This article analyses the tradition of “articulating xing in terms of sheng” and related other expressions, and also examines the debate between Mencius and Gaozi concerning “xing is known by sheng.” It claims that while Mencius’ “human nature is good” discourse is influenced by the interpretive tradition of “articulating xing in terms of sheng”, Mencius also transcends and develops this tradition. Therefore it is only when Mencius’ views about the goodness of human nature are understood in the context of this interpretive tradition that his ideas can be fully understood. Utilizing this framework, the Confucian understanding of rights is then explored. Translated by Andrew Lambert from Zhexue yanjiu 哲学研究 (Philosophical Researches), 2007, (7): 36–42     

Closed systems,explanations, and the cosmological argument

Examples involving infinite suspended chains or infinite trains are sometimes used to defend perceived weaknesses in traditional cosmological arguments. In this article, we distinguish two versions of the cosmological argument, suggest that such examples can only be relevant if it is one specific type of cosmological argument that is being considered, and then criticize the use of such examples in this particular type of cosmological argument. Our criticism revolves around a discussion of what it means to call a system closed, and what it means to call an explanation complete. Our analysis makes no suppositions about the nature of the infinite, and is therefore independent of many of the issues around which contemporary discussions of the cosmological argument have tended to revolve.     

Externalism and the Content of Moral Motivation

In his fetishist argument, Michael Smith raises an important question: What is the content of the motivational states that constitute moral motivation? Although the argument has been widely discussed, this question has not received the attention it deserves. In the present paper, I use Smith’s argument as a point of departure for a discussion of how advocates of externalism as regards moral judgements can account for moral motivation. More precisely, I explore various explanations of moral motivation that externalists can employ to answer the question Smith poses.