Acoustically evoked brain stem potentials in chronic alcoholism and withdrawal

BAEP studies hint at different neurophysiological findings between gamma and delta alcoholics. On the first day of withdrawal gamma alcoholics show slight vegetative withdrawal symptoms in the form of CNS hyperexitability trough the shortening of the early IPL. However delta alcoholics show prolongations of the late IPL which can be interpreted as a consequence of brain stem transmission disorders resulting from chronic intoxication. After four weeks the BAEP deviations found in both groups indicate a clear tendency of recovery which points to functional disorders.     

Acoustic evoked brain stem potentials in chronic alcoholic Korsakoff syndrome

29 patients with Korsakoff syndrome (KS) were examined by means of brainstem auditory evoked potentials. The interpeak-latencies were delayed cumulative with the most accentuation of IPL I-VI. BAEP are suitable for subdividing of KS. It is suggested that BAEP shall observed in alcoholics for detection of norm-deviations.     

Acoustically evoked brain stem potential in Wilson disease

By 48 patients with Wilson's disease the brainstem acoustic evoked potentials were stated. There were 35 pathological findings (73%), 13 were normal (27%). The waves, determined by the middle and upper brainstem (Pons and Mesencephalon) showed most of all pathological changes. Those patients with forms of Wilson's disease called Pseudoskelerose and Pseudoparkinson showed the most pathological findings. But one could watch these findings by about 30% of patients in preclinical stage. This method can possibly be used for early detection of disorders of brainstem functions and in the same way it can be used for control of treatment by patients in preclinical stage.     

The square search test in connection with acoustic evoked brain stem potentials

A random sample of 15 patients suffering from multiple sclerosis without acute episodes and at least partially able to work, shows to a high degree of statistical certainty that reduction in amplitude of acoustically evoked brain stem potentials (BAEP) is closely linked with beta-weighted performance value of the square search test (QSP).     

The diagnostic significance of auditory evoked brain stem potentials in multiple sclerosis

30 patients suffering from multiple sclerosis were examined by BERA among other audiological tests. In 47% we stated significant pathological BERA-latencies, in 53% pathological interpeak-intervals. The most patients have symptoms of brainstem, but 3 cases spinal symptoms. There are no constant correlations to subjective hearing threshold measurements. According to literature BERA, especially the measurement of interpeak-intervals, increases diagnostic security of the diagnosis multiple sclerosis.     

Effect of stimulus frequency on the latency of acoustically evoked brain stem potentials in children

Acoustically evoked brain stem potentials (HSP) are employed as an additional neurological investigation in child patients. A standardisation of the conditions of derivation would be desirable for the application of the method. In a pilot study, the influence of the excitation frequency on the latency of the HSP of 25 organically and neurologically healthy children was studied. Results show that absolute latencies are prolonged by increase of stimulus frequency, with the peripheral, cochleo-encephalic, and central traveling times remaining virtually unaffected.     

Auditory evoked potentials and sex-related differences in brain development

Auditory evoked potentials (AEPs) were obtained to probe tones which were delivered during the presentation of complex verbal and nonverbal auditory stimulation to 3-month-old infants. Significant sex-dependent AEP amplitude asymmetries were found. Females produced higher-amplitude responses from the left hemisphere and males produced higher-amplitude responses from the right hemisphere during both the verbal and nonverbal presentations. No significant AEP asymmetries were obtained in an independent group of infants that received only the probe tones. These findings are consistent with theories and behavioral data suggesting differences between males and females in the development of language and spatial functions.     

The value of auditory evoked brain stem potentials in the diagnosis of circulatory disorders in the area of vertebrobasilar circulation

The acoustically-evoked brain-stem potential in patients with vertebrobasilar insufficiency has enjoyed a varied diagnostic evaluation in the literature. Our own examinations reveal an advantage in subdividing AEBP changes into normal and marginal, slight and pronounced, within a group of patients with blood supply disorders in the vertebrobasilar region. AEBP permits inferences to be made on the extent of the damage. However, one should be chary of referring AEBP change of vascular origin to any particular section on the basis of these deductions alone. Only the comprehensive consideration of clinical symptoms, AEBP findings, and neuroradiological examination leads to a valid opinion on extent and location.     

State dependent modification of auditory brain stem potentials

It is well known, amplitudes and latencies of auditory brain stem potentials are almost independent of viligance state. Contrary to that, simple cognitive requirements effect amplitude changes (enhancement of variance, amplitude reduction) in a part 2/3) of the subjects.     

Reaction time,evoked brain potentials,and psychometric g in the severely retarded

Measurements derived from reaction time (RT), movement time (MT), and an index of neural adaptability (NA) derived from averaged evoked potentials are significantly related to each other as well as to g factor scores extracted from a battery of 15 psychometric tests in a sample of 54 severely retarded adults. The RT-MT and NA variables show a shrunken multiple R of .64 (p < .001) with psychometric g.     

Self-focused attention and the experience of alcoholic intoxication

The present study investigates the relationship between self-focused attention and the experience of emotional and bodily concomitants of alcoholic intoxication. It was hypothesized that self-focused attention would amplify salient mood and bodily concomitants of intoxication after alcohol intake and counteract these concomitants after placebo treatment. Self-focused attention was assessed by measures of private body consciousness, private self-consciousness, and of self-awareness. Since alcohol intake did not influence mood, it was not possible to test our main-hypothesis linking self-focused attention with the experience of mood concomitants of intoxication. As to bodily concomitants of intoxication a strong effect of alcohol intake was disclosed. Further analysis revealed the predicted relationship between self-awareness and private body consciousness on one hand and the experience of bodily concomitants of intoxication, on the other. The relationship between private body consciousness and experience of bodily concomitants of intoxication was moderated by the amount of experience with alcohol. No significant relationship between private self-consciousness and experience of bodily concomitants of intoxication was found.     

Long latency auditory evoked potentials

Experiment 1 elicited the P1, N1, P2, and N2 components of the long latency auditory evoked potential (AEP) using a 1000 Hz tone presented at 30, 50, or 70 dB SPL and 1-, 3-, or 5- second inter-stimulus intervals to assess the relative effects of the combination of these variables on component amplitude and latency. Four blocks of 16 tone presentations each were recorded from each subject to determine if changes in the AEP would occur because of short-term habituation. Both stimulus factors interacted significantly in a systematic fashion for the amplitude measures, with increases in latency also associated with increases in intensity and inter-stimulus interval. Only minor changes across the four trial blocks for either the amplitude or latency measures were observed over the various stimulus presentation conditions. Experiment 2 employed the same tone stimulus presented at 50 dB SPL and a 3-second inter-stimulus interval. Eight blocks of 64 trials were recorded from each subject on each day for four days to investigate long-term habituation effects. No substantial changes in any of the component amplitudes or latencies were obtained across the 32 trial blocks. It was concluded that intensity and inter-stimulus interval interact to determine AEP amplitude as well as latency values and that the constituent components do not change appreciably with repeated stimulus presentations, even after several days.     

Visual evoked potentials basic references

A list is given of 60 basic references (monographs and general reviews) in the field of evoked potentials and event-related brain potentials applied to vision research in man.     

The psychophysiology of the visual thought perception of visually evoked brain potentials and recognition mechanisms

The study tries to demonstrate, that the combination of the actualgenetic method (Sander, Froehlich), and the VEP, allows a systematic and differentiated analysis of the psychophysiological process of visual thinking. A student group was compared with mental retardates in VEP and EOG, watching actualgenetically manipulated picture series. Phasic EEG-changes are significantly related to the identification process. Most sensitive are amplitude changes about 120 to 270 msec. The mental retardates had significant VEP changes 180--270 msec, the students 128--192 msec after picture presentation. The process factor analysis (Pawlik) elaborated an illumination factor and two factors being labelled general reaction set. VEP averaging over the persons revealed different attention and/or discrimination behavior for the student group and the mental retardates, identifying the picture objects.     

Lateral dominance and visual evoked potentials in albinos

Lateral preferences for the use of eye, hand, and foot were assessed in 17 male and female albino subjects, aged 15 to 52 yr. Visual evoked potential (VEP) recordings suggested that optic fibres were abnormally decussated in these subjects, as others have shown. Fewer albino subjects showed the lateral preference for the use of hand/eye and foot/eye similar to that of normals. It is postulated that the abnormal decussation of optic fibres may underlie the reduced preference for the use of the same hand and eye, and foot and eye, in albinos.