儿科重症监护室中放弃治疗的相关问题研究

随着现代伦理学、生命质量和生命价值理论的发展,对于儿科重症监护室中部分病情危重且不可避免地将出现影响其远期生存质量的后遗症的患儿来说,选择放弃治疗可能更符合伦理学及患儿的最佳利益。对儿科重症监护室中部分患儿放弃治疗的实施过程、必备条件、常见原因、实施对象、相关伦理学及法律问题进行了探讨,以求为临床诊疗提供理论参考。     

新生儿重症监护室中放弃治疗的伦理问题

对于新生儿重症监护室中的一部分危重新生儿,虽然可以借助高新尖的医疗技术挽留他们的性命,但却不能避免其出现影响远期生存质量的后遗症。因此患儿家属和医务人员陷入了是否对这些危重新生儿实施放弃治疗的两难困境。对NICU中放弃治疗的对象、伦理学依据、伦理学意义以及如何实施放弃治疗的问题加以讨论,为NICU医务人员提供有益参考。     

ICU治疗实践的伦理问题辨析

从重症加强护理病房(intensive care unit, ICU)医生角度出发,通过工作中所接触的典型案例,提出患者入住ICU三个不同时间所产生的伦理问题,包括：患者入住ICU前,不同患者实际情况与ICU收治标准不符,作为ICU医生应在尊重患者自主意愿前提下,最大限度地完成治疗;患者于ICU治疗期间,ICU综合征及ICU后综合征产生原因及解决方案,家属代表患者做医疗决定时面临的两难抉择,ICU医生应该做好医患沟通工作,从多角度实施人文关怀;ICU治疗终末期患者生命尊严和短暂生存之间的选择,ICU医生应建议家属接受缓和医疗并介绍器官捐献参与过程中伦理原则。

     

With Hope and Imagination: Imaginative Moral Decision-Making in Neonatal Intensive Care Units

Although the role of imagination in moral reasoning is often neglected, recent literature, mostly of pragmatist signature, points to imagination as one of its central elements. In this article we develop some of their arguments by looking at the moral role of imagination in practice, in particular the practice of neonatal intensive care. Drawing on empirical research, we analyze a decision-making process in various stages: delivery, staff meeting, and reflection afterwards. We show how imagination aids medical practitioners demarcating moral categories, tuning their actions, and exploring long-range consequences of decisions. We argue that imagination helps to bring about at least four kinds of integration in the moral decision-making process: personal integration by creating a moral self-image in moments of reflection; social integration by aiding the conciliation of the diverging perspectives of the people involved; temporal integration by facilitating the parties to transcend the present moment and connect past, present, and future; and epistemological integration by helping to combine the various forms of knowledge and experience needed to make moral decisions. Furthermore, we argue that the role of imagination in these moral decision-processes is limited in several significant ways. Rather than being a solution itself, it is merely an aid and cannot replace the decision itself. Finally, there are also limits to the practical relevance of this theoretical reflection. In the end, it is up to care professionals as reflective practitioners to re-imagine the practice of intensive care and make the right decisions with hope and imagination.

ICU临终患者治疗抉择的伦理问题

医生面对ICU临终患者很难抉择是应该积极治疗到底还是提供舒适的保守治疗,目前相关的伦理及法律问题仍尚需完善,伦理指导是一项解决纠纷、政善沟通有效的工具,成立伦理委员会对医生进行合理的建议和指导是非常必要的。     

Nutrition and hydration: an analysis of the recent papal statement in the light of the Roman Catholic bioethical tradition.

This article discusses the unexpectedly firm stance professed by John Paul II on the provision of artificial nutrition and hydration to patients who are in a persistent vegetative state, and it implications on previously held standards of judging medical treatments. The traditional ordinary/extraordinary care distinction is assessed in light of complexities of the recent allocution as well as its impact on Catholic individuals and in Catholic health care facilities. Shannon concludes that the papal allocution infers that the average Catholic patient is incapable of making proper judgments about their own care. Shannon sees the preservation of life at all costs as at least highly troubling, if not as a radical move against the Catholic medical ethics tradition.     

ICU伦理问题的分析与对策

ICU伦理问题主要集中在：ICU的过度医疗现象;ICU忽视医学伦理的问题;ICU患者知情同意权的相关问题;长期入住ICU患者的经济伦理问题;ICU终末期患者治疗策略的伦理问题;ICU医护人员职业倦怠的相关伦理问题。通过对上述伦理问题的分析,提出了解决问题的伦理路径,主要包括以下几方面：加强医疗收费的合理性,防止出现过度医疗现象;加强ICU医护人员的责任感,提高医方的公信力;加强医患间的沟通,重视患方的知情权;对ICU临终患者坚持道义与功利相结合的原则;改善ICU进出标准,科学利用稀缺资源;加强ICU医学伦理知识的普及,缓解医患矛盾。     

医患双方对中晚期肺癌在EICU的治疗抉择

急诊重症监护室收治的肺癌中晚期患者往往因突发的危重并发症而打乱既往的抗肿瘤计划,因其病情特点呈现一定的可逆性,救治效果或好于传统终末期患者,家属对治疗的态度也更为积极,这些均不同于以往肿瘤自然进程发展下的终末期患者。从生存率及生存质量两个方面来着重探讨此类患者在急诊重症监护室中治疗能否获益,以及在救治患者的过程中,患者家属及医生对待放弃治疗时的矛盾心理及产生原因,并将就此问题提出尊严死教育的重要性,提出建立健全撤除生命支持系统的具体实施方案。

     

Adult Attachment Dimensions,World View Schemas,and the Psychological Health of Parents of Infants in a Neonatal Intensive Care Unit

This study reports the results of an exploration of the relationship of adult attachment dimensions (closeness, dependence, and anxiety) and world view assumptions (benevolence, meaningfulness, and worthiness) to psychological distress and psychological well-being in 142 parents (71 couples) of newborns recently hospitalized in a neonatal intensive care unit. The results of the Actor-Partner Interdependence Model, hierarchical multiple regression, and mediation analyses showed that parents who were more comfortable with attachment-dependence and parents who held more positive beliefs about benevolence and worthiness had less psychological distress and more well-being. In addition, parents with partners who were more comfortable with attachment-dependence had less psychological distress and more well-being. Attachment-dependence partially mediated the relationships of benevolence and worthiness with psychological distress and the relationship of benevolence with psychological well-being, whereas worthiness had a direct relationship with psychological well-being.     

ICU生命末期患者死亡质量量表的汉化及信效度评价

为了翻译并修订重症监护病房生命末期患者死亡质量量表(QODD-3.2A),形成中文版QODD-3.2A,并对其进行信效度检验,先采用Brislin翻译模式对QODD-3.2A进行翻译、回译、专家咨询、预调查后形成中文版QODD-3.2A,之后采用便利抽样方法,对湖北省两所综合医院182例死亡患者的死亡质量进行调查并评价其信效度。通过分析,中文版QODD-3.2A量表有6个维度,共24个条目,累计方差贡献率为67.47%,总量表的Cronbach'sα值为0.891,折半系数为0.801,量表水平的内容效度指数为0.94。中文版QODD-3.2A具有较好的信效度,可作为国内ICU生命末期患者死亡质量的评估工具。     

Traversing boundaries: clinical ethics,moral experience,and the withdrawal of life supports

While many have suggested that to withdraw medical interventions is ethically equivalent to withholding them, the moral complexity of actually withdrawing life supportive interventions from a patient cannot be ignored. Utilizing interplay between expository and narrative styles, and drawing upon our experiences with patients, families, nurses, and physicians when life supports have been withdrawn, we explore the changeable character of boundaries in end-of-life situations. We consider ways in which boundaries imply differences – for example, between cognition and performance – and how the encounter with boundaries can generate altered meanings important for understanding decisions and actions in these contexts. We conclude that the reliance on mere roles to support the moral weight of withdrawing medical interventions is inadequate. Roles that lead us to such moments are exceeded by the responsibility encountered in such moments. And here, we suggest, is the momentous character of withdrawal: it presents the grave astonishment, the trembling awe, in the not-being-there of the other in death.     

Dementia and Suffering in Nursing Homes

SUMMARY

This paper uses case studies of challenging behaviour associated with dementia to demonstrate, firstly, that disturbed behaviour is often a manifestation of suffering caused by multiple phenomena such as medical problems or the care environment. Addressing these causes instead of simplistically ‘treating the behaviour’ usually reduces the behaviour. Secondly, staff distress with a particular difficult resident is often caused by more general fundamental problems such as a lack of support or knowledge. Addressing these problems reduces staff distress. Finally, results from a Swedish intervention study are presented. They show that suffering for both staff and residents can be reduced, and quality of life improved, by providing increased autonomy for hands-on staff, systematic emotional support, and collaboratively developing care plans based on each resident's emotional and physical needs, rather than the problems they present.     

Dental pain related to quality of life and mental health in South Korean adults

High levels of stress, anxiety and depression have been reported in patients with orofacial pain. Dental pain has the potential to reduce quality of life (QOL), and pain relief is important aspect of QOL. The purpose of this study was to assess the relationships of dental pain with QOL and mental health using a nationally representative, population-based study. This study analyzed data from the 2012 Korea National Health and Nutrition Examination Survey (N = 5469). Oral health status was assessed using the oral health questionnaire, and oral examination was performed by trained dentists. Health-related QOL (HRQOL) was evaluated using EQ-5D and EQ-VAS, and mental health was evaluated by questionnaires. Logistic regression was applied to estimate adjusted odds ratios (AOR) and 95% confidence intervals (CI). Among 5469 adults, 1992 (36.42%) presented self-reported dental pain. Participants with anxiety/depression or pain/discomfort, and participants with stress, melancholy, suicidal thought or depression showed significantly higher prevalence of dental pain. After adjusting for covariates, five aspects of QOL and five aspects of mental health were related with dental pain. The AORs (95% CI) for dental pain were 1.39 (1.06–1.81) for mobility, 1.77 (1.19–2.63) for self-care, 1.38 (1.02–1.85) for usual activities, 1.73 (1.43–2.09) for pain/discomfort and 1.50 (1.13–1.98) for anxiety/depression. For mental health status factors, the AORs (95% CI) for dental pain were 1.29 (1.11–1.51) for stress, 1.37 (1.09–1.74) for melancholy, 1.26 (1.01–1.58) for suicidal thoughts, 1.43 (.93–2.19) for consultation to psychiatrist and 1.53 (1.07–2.19) for depression. This study showed that dental pain has an association with lower HRQOL and worse mental health status in South Korean adults.     

非医疗卫生机构医学伦理委员会现状及挑战

我国非医疗卫生机构正处于建立健全伦理委员会的阶段,其伦理委员会常见问题包括无针对性的伦理审查规范,审查能力无法匹配需求,伦理监管难以护航创新,可参考的指南和标准操作规程有限,研究者伦理知识有待提高,跟踪审查落实困难。鉴于此,建议落实法规基本规定,建立健全伦理委员会,人财物支持,提升委员审查能力,实行研究者准入制,建立伦理委员会认证制度和借鉴国外高等院校经验,以期加快非医疗卫生机构伦理委员会建设。

     

Infant illness severity and family adjustment in the aftermath of NICU hospitalization

Up to 15% of parents have an infant who will spend time in a neonatal intensive care unit (NICU). After discharge, parents may care for a medically fragile infant and worry about their development. The current study examined how infant illness severity is associated with family adjustment. Participants included parents with infants who had been discharged from the NICU 6 months to 3 years prior to study participation (N = 199). Via a Qualtrics online survey, parents reported their infants’ medical history, parenting stress, family burden, couple functioning, and access to resources. Multivariable regression analyses revealed that more severe infant medical issues during hospitalization (e.g., longer length of stay and more medical devices) were associated with greater family burden, but not stress or couple functioning. Infant health issues following hospitalization (i.e., medical diagnosis and more medical specialists) were associated with greater stress, poorer couple functioning, and greater family burden. Less time for parents was associated with increased stress and poorer couple functioning. Surprisingly, parents of infants who were rehospitalized reported less stress and better couple functioning, but greater family burden. Family-focused interventions that incorporate psychoeducation about provider−patient communication, partner support, and self-care may be effective to prevent negative psychosocial sequelae among families.