Early executive functioning in a global context: Developmental continuity and family protective factors

This study extends the methodological and theoretical understanding of executive functions (EFs) in preschoolers from low‐ and middle‐income countries (LMIC). First, the authors describe a rigorous process of adapting and evaluating six EF tasks to produce a culturally and developmentally appropriate measure of emerging EFs in a large sample of at‐risk children in rural Pakistan. Next, the authors identify critical developmental and family factors that relate to preschoolers’ EFs over the first 4 years of life. Direct assessment of children's general cognitive skills at age two showed developmental continuity with EFs at age four, and these early cognitive skills mediated the effect of an antecedent parenting intervention on EFs as well as associations of targeted individual and family factors with EFs. Furthermore, directly assessed maternal cognitive capacities and observed maternal scaffolding uniquely predicted EFs in preschoolers. This study is also the first to demonstrate a significant overlap between direct assessments of IQ and EFs in young children from LMIC. Children's general intelligence mediated the associations of EFs with antecedent physical growth and cognitive skills as well as concurrent family factors (maternal verbal intelligence, maternal scaffolding, and home stimulation). After controlling for shared variance between preschoolers’ general intelligence and EFs, three factors emerged as unique predictors of EFs: exposure to an early parenting intervention, physical growth status at age two, and number of older siblings. The findings have important implications for the design of interventions that aim to improve EFs in young children in LMIC. A video abstract of this article can be viewed at https://vimeo.com/316329544/5abde94cd7     

Executive function in paediatric medulloblastoma: The role of cerebrocerebellar connections

Executive functions (EFs) are involved in the attainment, maintenance, and integration of information; these functions may play a key role in cognitive and behavioural outcomes in children treated for medulloblastoma (MB). At present, it remains unclear which EFs are most sensitive to the treatment effects for MB and whether damage to cerebrocerebellar circuitry is associated with EF. We completed a comprehensive evaluation of EF in 24 children treated for MB and 20 age‐matched healthy children (HC) and distilled these measures into components. Six components (C1–C6) were extracted from our model, reflecting dissociable constructs of EF: C1 = cognitive efficiency; C2 = planning/problem‐solving; C3 = positive cognitive emotion regulation; C4 = working memory; C5 = negative cognitive emotion regulation; and C6 = mixed cognitive emotion regulation. Group differences were found for C1, C2, C3, and C4; the MB group showed poorer performance on EF tasks and made less use of positive cognitive emotion regulation strategies relative to HC. Compromise to cerebrocerebellar microstructure – cerebro‐ponto‐cerebellar and cerebello‐thalamo‐cerebral pathways – was evident in children treated for MB compared to HC. We found that cerebrocerebellar circuitry has a mediating effect on one component of EF following treatment for MB – working memory.     

Socioeconomic status and executive function: developmental trajectories and mediation

Childhood socioeconomic status (SES) predicts executive function (EF), but fundamental aspects of this relation remain unknown: the developmental course of the SES disparity, its continued sensitivity to SES changes during that course, and the features of childhood experience responsible for the SES–EF relation. Regarding course, early disparities would be expected to grow during development if caused by accumulating stressors at a given constant level of SES. Alternatively, they would narrow if schooling partly compensates for the effects of earlier deprivation, allowing lower‐SES children to ‘catch up’. The potential for later childhood SES change to affect EF is also unknown. Regarding mediating factors, previous analyses produced mixed answers, possibly due to correlation amongst candidate mediators. We address these issues with measures of SES, working memory and planning, along with multiple candidate mediators, from the NICHD Study of Early Childcare (n = 1009). Early family income‐to‐needs and maternal education predicted planning by first grade, and income‐to‐needs predicted working memory performance at 54 months. Effects of early SES remained consistent through middle childhood, indicating that the relation between early indicators of SES and EF emerges in childhood and persists without narrowing or widening across early and middle childhood. Changes in family income‐to‐needs were associated with significant changes in planning and trend‐level changes in working memory. Mediation analyses supported the role of early childhood home characteristics in explaining the association between SES and EF, while early childhood maternal sensitivity was specifically implicated in the association between maternal education and planning. Early emerging and persistent SES‐related differences in EF, partially explained by characteristics of the home and family environment, are thus a potential source of socioeconomic disparities in achievement and health across development.     

Genetic and environmental influences on executive functions and intelligence in middle childhood

Executive functions (EFs) and intelligence (IQ) are phenotypically correlated. In twin studies, latent variables for EFs and IQ display moderate to high heritability estimates; however, they show variable genetic correlations in twin studies spanning childhood to middle age. We analyzed data from over 11,000 children (9- to 10-year-olds, including 749 twin pairs) in the Adolescent Brain Cognitive Development (ABCD) Study to examine the phenotypic and genetic relations between EFs and IQ in childhood. We identified two EF factors—Common EF and Updating-Specific—which were both related to IQ (rs = 0.64–0.81). Common EF and IQ were heritable (53%–67%), and their genetic correlation (rG = 0.86) was not significantly different than 1. These results suggest that EFs and IQ are phenotypically but not genetically separable in middle childhood, meaning that this phenotypic separability may be influenced by environmental factors.     

A longitudinal intergenerational analysis of executive functions during early childhood

Despite the importance of executive function (EF) in both clinical and educational contexts, the aetiology of individual differences in early childhood EF remains poorly understood. This study provides the first longitudinal intergenerational analysis of mother–child EF associations during early childhood. A group of children and their mothers (n = 62) completed age‐appropriate EF tasks. Mother and child EFs were modestly correlated by 24 months of age, and this association was stable through 48 months. Importantly, maternal–child EF associations were still robust after controlling for verbal ability (potential indicator of verbal/crystallized intelligence) and maternal education (correlate of socio‐economic status and verbal intelligence). Potential implications of these findings as well as underlying mechanisms of the maternal–child EF association (gene–environment interplay) are discussed.     

Dimensions of executive functioning: Evidence from children

This study investigated dimensions of executive functioning in 8‐ to 13‐year‐old children. Three tasks from the Cambridge Neuropsychological Test Automated Battery (CANTAB), two tasks from the NEPSY battery and some additional executive function (EF) tests were administered to 108 children. In line with earlier work, modest correlations among EF measures were obtained (r < .4). Both exploratory and confirmatory factor analyses yielded three interrelated factors, which resembled those obtained by Miyake et al. (2000) and which were—with some reservations—labelled Working Memory (WM), Inhibition and Shifting. Age correlated with performance on most individual EF measures as well as Shifting and WM. The present findings are in agreement with contemporary views as to the simultaneous unity and diversity of EFs.     

A meta‐analysis of the relationship between socioeconomic status and executive function performance among children

The relationship between childhood socioeconomic status (SES) and executive function (EF) has recently attracted attention within psychology, following reports of substantial SES disparities in children's EF. Adding to the importance of this relationship, EF has been proposed as a mediator of socioeconomic disparities in lifelong achievement and health. However, evidence about the relationship between childhood SES and EF is mixed, and there has been no systematic attempt to evaluate this relationship across studies. This meta‐analysis systematically reviewed the literature for studies in which samples of children varying in SES were evaluated on EF, including studies with and without primary hypotheses about SES. The analysis included 8760 children between the ages of 2 and 18 gathered from 25 independent samples. Analyses showed a small but statistically significant correlation between SES and EF across all studies (r_random = .16, 95% CI [.12, .21]) without correcting for attenuation owing to range restriction or measurement unreliability. Substantial heterogeneity was observed among studies, and a number of factors, including the amount of SES variability in the sample and the number of EF measures used, emerged as moderators. Using only the 15 studies with meaningful SES variability in the sample, the average correlation between SES and EF was small‐to‐medium in size (r_random = .22, 95% CI [.17, .27]). Using only the six studies with multiple measures of EF, the relationship was medium in size (r_random = .28, 95% CI [.18, .37]). In sum, this meta‐analysis supports the presence of SES disparities in EF and suggests that they are between small and medium in size, depending on the methods used to measure them.     

Inhibitory control and set shifting describe different pathways from behavioral inhibition to socially anxious behavior

Individuals with a behaviorally inhibited (BI) temperament are more likely to develop social anxiety. However, the mechanisms by which socially anxious behavior emerges from BI are unclear. Variation in different forms of top‐down control, specifically executive functions (EF), may play distinct roles and characterize differential pathways to social anxiety. Here 291 children were assessed for BI in toddlerhood (ages 2 and 3), parent‐reported inhibitory control and set shifting during middle childhood (age 7), and multidimensional assessment of socially anxious behavior completed during late childhood and early adolescence (ages 9 and 12). Structural equation modeling revealed that early variation in BI predicted the development of socially anxious behavior through either higher levels of parent‐reported inhibitory control or lower levels of parent‐reported set shifting. These data reinforce the notion that top‐down control does not uniformly influence relations between temperament and socially anxious behavior. These data suggest novel approaches to thinking about the role of EFs and social anxiety outcomes as children approach adolescence.     

Family socioeconomic status and emotional adaptation among rural‐to‐urban migrant adolescents in China: The moderating roles of adolescent's resilience and parental positive emotion

Low family socioeconomic status (SES) is closely related to increased risk of emotional maladaptation among adolescents. Although previous studies have found that low family SES is a significant and common experience for most rural‐to‐urban migrant adolescents in China, little research has examined the association between family SES and emotional adaptation or identified the protective factors that may minimise emotional maladaptation among these adolescents. The present study examined the associations between family SES and three indices of emotional adaptation (emotion regulation, life satisfaction and depression) and the moderating effects of adolescents' resilience and parental positive emotion (PE) among 486 Chinese rural‐to‐urban migrant adolescents. The results suggest that family SES was significantly associated with migrant adolescents' emotional outcomes, to varying degrees. Moreover, both adolescents' resilience and PE moderated the associations between family SES and emotional outcomes, although the protective effects of the two moderators differed on the three emotional outcomes. These findings shed light into designing intervention and prevention programs to reduce emotional maladaptation among migrant adolescents.     

Hot executive function following moderate‐to‐late preterm birth: altered delay discounting at 4 years of age

Interest in monitoring long‐term neurodevelopmental outcomes of children born moderate‐to‐late preterm (32–36 weeks gestation) is increasing. Moderate‐to‐late preterm birth has a negative impact on academic achievement, which may relate to differential development of executive function (EF). Prior studies reporting deficits in EF in preterm children have almost exclusively assessed EF in affectively neutral contexts in high‐risk preterm children (< 32 weeks gestation). Disrupted function in motivational or emotionally charged contexts (hot EF) following preterm birth remains uninvestigated, despite evidence that preterm children show differential development of neural circuitry subserving hot EF, including reduced orbitofrontal cortex volume. The present study is the first to examine whether low‐risk, healthy children born moderate‐to‐late preterm exhibit impairments in the development of hot EF. Preterm children at age 4.5 years were less likely to choose larger, delayed rewards across all levels of reward magnitude on a delay discounting task using tangible rewards, but performed more similarly to their full‐term peers on a delay aversion task involving abstract rewards and on measures of cool EF. The relationship between gestational age at birth and selection of delayed rewards extended across the entire gestational age range of the sample (32–42 weeks), and remained significant after controlling for intelligence and processing speed. Results imply that there is not a finite cut‐off point at which children are spared from potential long‐term neurodevelopmental effects of PT birth. Further investigation of reward processing and hot EF in individuals with a history of PT birth is warranted given the susceptibility of prefrontal cortex development to early environmental variations.     

The Role of Psychological Characteristics in the Relation Between Socioeconomic Status and Perceived Health1

Separate analyses of United States and Finnish samples demonstrate a graded (almost linear) relation between socioeconomic status (SES) and risk of poor perceived health. In both studies, positive psychological factors (greater social support; less anger, depression, and perceived stress) and beneficial health practices (nonsmoking; drinking and exercising moderately) were associated with both higher levels of SES and better self-reported health. Psychological and health practice variables were both able to account for some of the SES and poor health gradient. However, contrary to expectations, these factors did not play a more important role in explaining decreased risk at the middle and highest levels of SES, and instead may be most important at lowest levels.     

Socioeconomic gradients predict individual differences in neurocognitive abilities

Socioeconomic status (SES) is associated with childhood cognitive achievement. In previous research we found that this association shows neural specificity; specifically we found that groups of low and middle SES children differed disproportionately in perisylvian/language and prefrontal/executive abilities relative to other neurocognitive abilities. Here we address several new questions: To what extent does this disparity between groups reflect a gradient of SES‐related individual differences in neurocognitive development, as opposed to a more categorical difference? What other neurocognitive systems differ across individuals as a function of SES? Does linguistic ability mediate SES differences in other systems? And how do specific prefrontal/executive subsystems vary with SES? One hundred and fifty healthy, socioeconomically diverse first‐graders were administered tasks tapping language, visuospatial skills, memory, working memory, cognitive control, and reward processing. SES explained over 30% of the variance in language, and a smaller but highly significant portion of the variance in most other systems. Statistically mediating factors and possible interventional approaches are discussed.     

Turkish Children's Expression of Negative Emotions: Intracultural Variations Related to Socioeconomic Status

The goal of the present study was to examine intracultural variations in Turkish children's emotion expression in relation to socioeconomic status (SES) characteristics, alone and in combination with child gender and their interaction partners. Children's expectations about outcomes from expressing and their reasons for hiding their felt emotion in situations that involved unfairness, disappointment, public failure and a mishap were also delineated. A total of 123 school‐aged Turkish children responded to hypothetical vignettes. Boys and girls from middle‐high SES families were equally likely to endorse shame expression. However, lower SES boys were more likely to endorse hiding shame than lower SES girls. Middle‐high SES children showed a tendency for expressing anger and sadness more than lower SES children. Turkish children primarily expected interpersonal support from emotion expression. Upon anger, disappointment and sadness expression, Turkish children expected instrumental support more from their parents than their peers. The intracultural differences are discussed in light of sociodemographic changes accompanied by cultural value shifts that differentially impact socialization goals and practices of families with different SES. Copyright © 2015 John Wiley & Sons, Ltd.     

Middle school students’ perceptions of quality of life

Data are reported on 2278 public middle school students in South Carolina, U.S.A. Levels and demographic effects on their satisfaction with their overall lives as well as five specific domains (family, friends, self, school, and living environment) were assessed. Similar to findings with adults and high school students, most middle schoolers reported positive levels of global and domain-specific life satisfaction. Although statistically significant in some cases, the practical significance of the demographic variables was limited. Many middle schoolers reported particular dissatisfaction with their school experiences.     

Pedagogical strategies for teaching literacy to ESL immigrant students: A meta‐analysis

Background. Many countries rely on immigrants for population growth and to maintain a skilled workforce. However, many such immigrants face literacy‐related barriers to success in education and in the labour force. Aims. This meta‐analysis reviews experimental and quasi‐experimental studies to examine strategies for teaching English literacy to immigrant students. Method. Following an exhaustive and systematic search for studies meeting pre‐determined inclusion criteria, two researchers independently extracted data from 26 English as a Second Language (ESL) studies involving 3,150 participants. These participants consisted of ESL immigrant students in kindergarten through grade 6 who were exposed to English literacy instructional interventions. Measured outcomes were reading and writing. Results and Conclusions. Mean effect sizes vary from small to large, depending on instructional interventions and outcome constructs. Across several different grade levels, settings, and methodological features, pedagogical strategies used in teaching ESL to immigrant students are associated with increased competence in reading and writing. Collaborative reading interventions, in which peers engage in oral interaction and cooperatively negotiate meaning and a shared understanding of texts, produced larger effects than systematic phonics instruction and multimedia‐assisted reading interventions. The results show that the pedagogical strategies examined in this meta‐analysis produced statistically significant benefits for students in all grade levels. The findings also show that students from low socio‐economic status (SES) background benefit from ESL literacy interventions. However, significant heterogeneity was found in each subset. Educators and policy makers are encouraged to consider specific school contexts when making decisions about optimal pedagogical strategies. It is possible that contextual factors as well as ESL learner characteristics may influence the effectiveness of these strategies. To ensure literacy acquisition for immigrant students whose primary language is not English, it is important to continue to research successful literacy practices in ways that better inform educators and policy makers.     

The effectiveness of a school mindfulness-based intervention on the neural correlates of inhibitory control in children at risk: A randomized control trial

Interest in the applications of mindfulness practice in education is growing in the scientific community. Recent research has shown that mindfulness practice in schools may be beneficial for executive functions (EFs) which are abilities crucial for healthy development. The study of the effects of mindfulness practices on children's neural correlates of EFs, particularly inhibitory control, may provide relevant information about the impact and mechanisms of mindfulness-based interventions (MBIs) in children. The aim of the present study was to investigate the effects of a MBI in elementary school children on the neural correlates of inhibitory control via a randomized controlled trial. Children from two 4th grade classrooms and two 5th grade classrooms located in a school identified as having low socioeconomic status in Santiago de Chile were randomly assigned to either receive a MBI or serve as active controls and receive a social skills program. Both before and after the interventions, electroencephalographic activity was recorded during a modified version of the Go/Nogo task in a subsample of children in each group. Additionally, teachers completed questionnaires of students’ EFs and students completed self-report measures. Results revealed increases in EFs assessed by questionnaires together with improved P3 amplitude associated with successful response inhibition in children who received the MBI compared to active controls. These results contribute to the understanding of the ways in which mindfulness practices can promote the development of inhibitory control together with EF improvement, factors identified as critical for children's social and emotional development and positive mental health.

Research Highlights

• This study investigated the effects of a mindfulness-based intervention in children from a low socioeconomic status school on neural correlates of EFs.
• Children performed a Go/Nogo task while electroencephalographic activity was recorded and completed questionnaires before and after a MBI or an active control program.
• Improvements in EFs assessed by questionnaires together with an increased Nogo-P3 activity associated with successful inhibition in children who received the MBI were found.
• The results could contribute to understand how mindfulness practice can promote the development of inhibitory control in children from vulnerable populations.

     

Contexts as moderators of observed interactions: a study of Costa Rican mothers and infants from differing socioeconomic backgrounds

20 first-born infants from low socioeconomic status (SES) families and 20 first-born infants from middle SES families in Costa Rica were observed for 12 hours when they were 14 weeks old. The goals of this study were the following: 1) to study the impact of length of observation and context on the authors measures of interactional engagement; 2) to compare the interactional experiences of the infants in the two groups in various functional (e.g. feeding, object play) and social (e.g. with mother, with mother and others) contexts. Attuned and disharmonious interactions, as well as the frequency of positive affect, soothing, and vocalization, varied considerably across the functional contexts. In addition, disharmonious interactions increased and interactional engagement decreased when mothers and infants were joined by others. Highly unstable measures of individual differences were obtained when observations were limited to 45-minute blocks, but stability increased considerably as the duration of the observations expanded. The groups did not differ with respect to amounts of time spent in various functional and social contexts, in attuned or disharmonious states, or in high levels of interactional engagement. Within some of the functional contexts, however, significant group differences in levels of attuned interactions, infant vocalization, and maternal response vocalization were found. Overall, functional and social contexts clearly moderated interactional experiences. SES effects on verbal and other interactional measures were limited to some contexts and may thus represent the infants' overall experiences quite poorly. Consequently, comparisons based on a single context may be inadequate for studies of subjects from differing socioeconomic backgrounds.     

Parents Taking Action: A Psycho‐Educational Intervention for Latino Parents of Children With Autism Spectrum Disorder

The increased prevalence of autism spectrum disorder (ASD) among Latino children, later diagnosis, limited access to bicultural specialist support, and worsened health outcomes when compared to non‐Latinos points to the need for a culturally relevant parent education intervention. This pilot study examined the feasibility, acceptability, and preliminary outcomes of a culturally derived intervention, Parents Taking Action, for 19 Spanish‐speaking mothers of children with ASD. This study introduces the Promotora de Salud Model of intervention delivery to the autism field. A mixed‐methods design including one group pre‐ and posttest design and focus groups was used to evaluate the outcomes of PTA. We found that the intervention was both feasible to implement and acceptable to participants. We also found significant increases in empowerment oriented outcomes for parents between pre‐ and posttest suggesting that the intervention is promising. Suggestions for future research and practice are offered.     

Performance on Stroop‐like assessments of inhibitory control by 4‐ and 5‐year‐old children

The rapid development of an aspect of executive functioning (EF), inhibitory control (IC), between the ages of 3‐ and 5‐years, leads to an increase in a child's capacity to suppress inappropriate responding and therefore activate the necessary resources to carry‐out goal‐directed activity (Psychological Bulletin, 1997, 121 , 65–94). To measure EF in children, tasks administered clinically to adults are adapted. The Day–Night Stroop (DNS) is a pictorial modification of the Stroop Test (Journal of Experimental Psychology, 1935, 18 , 642–662), developed for pre‐literate children. Although suitable as a measure of IC in 3‐ to 4‐year‐old children, ceiling effects have been reported on the DNS in slightly older preschoolers. The present study attempted to overcome this limitation by examining the suitability of two modified versions of the DNS in 4‐ to 5‐year‐old preschoolers. To investigate the executive demands made by both Stroop‐like tasks, their associations with another measure of IC (stop‐signal task) and a measure of working memory were examined. Counter to expectations, no significant association was found in performance between the two Stroop‐like tasks; however, the modified DNS developed in this study showed significant relationships with the other executive tasks. The results are discussed in relation to the different methodologies used by these Stroop measures. Implications of this study suggest that researchers should consider more test‐specific factors when assessing EF in young children. Copyright © 2010 John Wiley & Sons, Ltd.     

Effectiveness of an ACT‐based rehabilitation program for the treatment of chronic fatigue: Results from a 12‐months longitudinal study

Acceptance and Commitment Therapy (ACT) is potentially effective for treating chronic fatigue. Given the paucity of studies on this topic, we aimed to assess long‐term trajectories of primary (fatigue, quality of life and functional abilities) and secondary outcomes (anxious and depressive symptoms) of an ACT‐based rehabilitation program for patients with chronic fatigue. Further, we examined if changes in potential process variables (psychological inflexibility, metacognitive beliefs, and cognitive and behavioral responses to symptoms) during ACT predicted change in all outcomes across follow‐up. One‐hundred ninety‐five workers on sick leave (mean age: 43.61 ± 9.33 years; 80.5% females) with a diagnosis of chronic fatigue were enrolled in a manualized, 3.5‐week intensive return‐to‐work rehabilitation program based on ACT. All completed a battery of questionnaires at pre‐, post‐treatment, 6 and 12 months follow‐up. We found significant longitudinal changes in most primary and secondary outcomes from pre‐ up to 12 months follow‐up. All process variables significantly decreased from pre‐ up to 12 months follow‐up, and pre‐to‐post changes in fear avoidance beliefs were most often associated with a greater change in outcomes across follow‐up. Depressive symptomatology showed a similar trajectory of change to fatigue, meaning that scores were correlated at each time point and tended to converge over time. This suggests that both symptoms influence each other substantially over a year following the treatment. Concluding, results lend support to the effectiveness of an ACT‐based rehabilitation program for patients with chronic fatigue and provide preliminary evidence for the role of process variables and depressive symptomatology on subsequent change in outcomes.