“What is this Genetics,Anyway?” Understandings of Genetics,Illness Causality and Inheritance Among British Pakistani Users of Genetic Services

Misconceptions about basic genetic concepts and inheritance patterns may be widespread in the general population. This paper investigates understandings of genetics, illness causality and inheritance among British Pakistanis referred to a UK genetics clinic. During participant observation of genetics clinic consultations and semi-structured interviews in Urdu or English in respondents’ homes, we identified an array of environmental, behavioral and spiritual understandings of the causes of medical and intellectual problems. Misconceptions about the location of genetic information in the body and of genetic mechanisms of inheritance were common, reflected the range of everyday theories observed for White British patients and included the belief that a child receives more genetic material from the father than the mother. Despite some participants’ conversational use of genetic terminology, some patients had assimilated genetic information in ways that conflict with genetic theory with potentially serious clinical consequences. Additionally, skepticism of genetic theories of illness reflected a rejection of a dominant discourse of genetic risk that stigmatizes cousin marriages. Patients referred to genetics clinics may not easily surrender their lay or personal theories about the causes of their own or their child’s condition and their understandings of genetic risk. Genetic counselors may need to identify, work with and at times challenge patients’ understandings of illness causality and inheritance.     

The Role of Domain-Specific Knowledge in Generative Reasoning About Complicated Multileveled Phenomena

Promoting the ability to reason generatively about novel phenomena and problems students may encounter in their everyday lives is a major goal of science education. This goal proves to be a formidable challenge in domains, such as molecular genetics, for which the accumulated scientific understandings are daunting in both amount and complexity. To develop effective instruction that fosters generative reasoning we need to have a sound understanding of the types of knowledge in the domain that are critical for such reasoning. In this study I examined the ensemble of knowledge, both general and domain-specific, undergraduate students employed in reasoning about problems in genetics. I found that students initially formulate a solution in terms that are not domain specific and that serve as a frame–solution frame–that outlines and constrains a more specific and domain-appropriate explanation. This solution frame is then filled in with two powerful forms of domain-specific knowledge I term: domain-specific heuristics and domain-specific explanatory schemas. These knowledge forms embody understandings of central mechanisms and entities in molecular genetics. By invoking these domain-specific knowledge forms, students were able to reason about a variety of both familiar and novel genetics problems. I present a cognitive model that highlights the role of these powerful conceptual understandings in promoting generative reasoning in genetics.     

Sex Differences and/in the Self: Classic Themes, Feminist Variations, Postmodern Challenges

This article examines perspectives on and intersections between two recurrent themes in the history of American psychology: sex differences and theories of self. These themes and certain connections between them are considered in three eras: early American psychology, feminist psychology coincident with the second wave of feminism, and the recent postmodern turn in psychology. A contextual analysis of parallels and contrasts among theories of sex differences and of the self in these three eras highlights problems with modernist understandings, especially with essentialist construals of gender and individualistic understandings of self. The article presents relationally defined postmodern views of gender and self, and comments on their promise for the present era of globalization and the consequent increasing attention to interconnections among people.     

‘We Are All the Same,We All Are Mestizos’: Imagined Populations and Nations in Genetics Research in Colombia

In Colombia, as in other Latin American countries, current population genetics research is based on the understanding that Colombians constitute a mestizo nation, given the admixture process that took place between Africans, Amerindians, and Europeans during colonial times. The mestizo is a pervasive category used by geneticists to conduct, organise, and publish research studies that deal with the continent's peopling process and the genetic makeup of its contemporary population(s). It is also the dominant imaginary for the Colombian population and a key nation-building ideology. By tracing how this category moves and is used across four Colombian genetics laboratories, it is possible to discern that despite its apparently clear-cut boundaries, the mestizo is contingent, contested, and flexible, allowing for multiple understandings and usages. This flexibility and multiplicity are visible in the quantification of genetic ancestry, the divisions of geographical location, and the understanding of gender. Such understandings allow one to think about a homogeneous nation (inclusive) that is simultaneously heterogeneous (exclusive); they provide multiple but not necessarily contradictory possibilities of being mestizo, allowing the coexistence of images of the nation that could otherwise seem contradictory; and they permit navigation around contested terms such as race, while simultaneously thinking of mixed races or racialised individuals. Finally, these flexible and multiple constructions of the mestizo (re)produce various subjects as ‘other’, whether they are women, the Indigenous, the black/dark, or the poor.     

Barriers to and Motivations for Physician Referral of Patients to Cancer Genetics Clinics

Although it is well known that under-referral of colon cancer patients to cancer genetics clinics is a chronic problem, no study has yet examined why physicians may be ordering testing independently rather than referring patients to cancer genetics clinics. The current study explored variables which may impact a physician’s preference for ordering testing independently or referring patients to outside cancer genetics experts. An online questionnaire, distributed to the membership of the American College of Gastroenterology and the American Society of Colorectal Surgeons, yielded responses from 298 physicians. Motivations to refer to cancer genetics clinics rather than order testing independently included fear of genetic discrimination and a belief that patients benefit from genetic counseling about the risks, benefits and consequences of testing. These results suggest that in order to increase referrals, genetic counselors must educate physicians about the unique benefits patients receive from participating in genetic counseling.     

‘Things said or done long ago are recalled and remembered’: The ethics of mindfulness in early Buddhism,psychotherapy and clinical psychology

I argue that current theoretical understandings of mindfulness as an attention regulation strategy for psychological stress reduction and enhanced adaptation to society may produce de-ethicised therapeutic applications. I show how understandings of mindfulness in early Buddhism, psychotherapy and clinical psychology have changed over time. Current understandings of mindfulness as a skill or technique of bringing non-judgmental awareness (or bare attention) to present moment experience are historically recent and differ from early Buddhist understandings in at least one crucial respect: definitions of mindfulness as attentional control or metacognitive awareness lack an emphasis on deep ethical reflection. As such, we need to re-ethicise our conceptual understanding of mindfulness by remembering early Buddhist texts, where mindfulness involves the cultivation of an ethically sensitive style of remembering, which has largely been lost in contemporary definitions.     

‘You beat ‘em,we feed ‘em!’: Enfolding laughter and pride

In this article I use the affective politics of laughter as an entry point into broadening understandings of the political potentiality of the everyday geographies of pride, centralizing in my analysis a safe house for women involved in street level sex work. I look to the ways in which the encounters between laughter and pride in this space expose its inextricability from bodily vitality and survival, feelings of collective belonging, and structural realities and inequalities. Using Gilles Deleuze's concept of the fold to structure my analysis, I use laughter as a lens to advance an understanding of pride that emphasizes its entanglement with collective affect and its immanent multiplicity as it is embodied through everyday encounters with difference. I emphasize the affective component of laughter's foldings as a means to think through the way vibrational pulls, pushes, tenors and tones work to move bodies toward or away from collectives, spaces, politics, ideas, relationships and ways of living. Exploring pride through the affective politics of laughter is a way to advance understandings of pride as emerging always in relation to collectives, histories, and spaces, rather than as an individual trait. Such a reframing has implications for understanding affective politics as a resource for social justice projects.     

Low Prospects and High Risk: Structural Determinants of Health Associated with Sexual Risk Among Young African American Women Residing in Resource-Poor Communities in the South

African American women at increased risk of HIV/sexually transmitted infection (STI) may engage in risky sex as a coping mechanism for depressed economic conditions. This study examines the association between high-risk sexual behavior and structural determinants of sexual health among a sample of young African American women. 237 young African American women (16–19 years old) from economically disadvantaged neighborhoods in North Carolina were enrolled into a randomized trial testing the efficacy of an adapted HIV/STI prevention intervention. Logistic regression analyses predicted the likelihood that young women reporting lack of food at home, homelessness and low future prospects would also report sexual risk behaviors. Young women reporting a lack of food at home (22 %), homelessness (27 %), and low perceived education/employment prospects (19 %) had between 2.2 and 4.7 times the odds as those not reporting these risk factors of reporting multiple sex partners, risky sex partners including older men and partners involved in gangs, substance use prior to sex, and exchange sex. Self-reported structural determinants of sexual health were associated with myriad sexual risk behaviors. Diminished economic conditions among these young women may lead to sexual risk due to hopelessness, the need for survival or other factors.     

Intergenerational transfer of individual differences in hereditary monarchs: genetic, role-modeling, cohort, or sociocultural effects?

Individual differences may be transferred across generations through either genetic inheritance, identification with role models, cohort effects, or sociocultural influences. Each of these four possible mechanisms makes different predictions regarding what traits display intergenerational continuities, the pattern of relationships between an individual and his or her relatives, as well as the relative impact of same-sex and cross-sex relationships. A sample of 342 hereditary monarchs was drawn from 14 European nations. These rulers, along with their parents, grandparents, and predecessors, were then assessed on the variables of intelligence, morality, eminence, leadership, life span, and reign span. Theoretically significant interaction effects were also operationalized using such moderator variables as genetic relationship, years of overlap in lives, age difference, difference in reign midpoints, and sex. The intergenerational transfer of intelligence and life span appears to be best explained by genetics, whereas the transfer of morality and eminence seems to be governed by role-modeling processes. The remaining variables were either transferred by more complex mechanisms (viz. leadership) or not transferred at all from one generation to the next (viz. reign span). The results contradict both Woods's (1906) belief that morality is genetically inherited and Galton's (1869) argument that eminence can served as a nearly equivalent proxy variable for intellectual genius.     

Sport-Related Concussions: A Review of Epidemiology, Challenges in Diagnosis, and Potential Risk Factors

Sport-related concussion (SRC) is a common mild traumatic brain injury among young, active individuals, affecting approximately 300,000 young American adults annually. In this review of the epidemiology of SRC, we describe the challenges in identifying concussion occurrence and review the studies describing concussion incidence in various sports. In high risk contact sports, American football, soccer (European football), hockey, lacrosse, and basketball athletes experience concussion unintentionally during the course of play. Among these, football concussion incidence is reviewed in greatest detail because it has the highest incidence among the contact sports, and some studies have shown long-term neurophysiologic and neurodegenerative outcomes. Mechanisms of injury differ significantly by sport and can be potential targets for concussion risk mitigation. Despite the apparent high incidence of SRC, risk factors determining initial concussion, recovery periods, recurrence, and long-term outcomes remain poorly understood and warrant further study exploring the influence of age, sex, genetics, and athletic factors.     

THE PERCEIVED VALUE OF DIRECT AND INDIRECT INFLUENCE STRATEGIES:

In this study, we assessed the generalizability of the Western preference for direct versus indirect influence strategies and its relation to participant sex, perceptions of participant power, and concerns for politeness among a sample of 138 American, 41 Japanese, and 44 Korean female and male college students. Regardless of cultural group or participant sex, direct strategies were reported as first choice strategies, whereas indirect strategies were cited as strategies of last resort. Participant power, not participant sex, was predictive of the students'reported strategy use. Although the American, Japanese, and Korean students were more similar than different on measures of perceived power and frequency of strategy use, concerns for politeness were reflected in the Japanese and Korean students'less confrontational strategy style.     

Understanding the Relationship between Religiosity and Caregiver–Adolescent Communication About Sex within African-American Families

Caregiver–adolescent communication about sex plays a critical role in the sexual socialization of youth. Many caregivers, however, do not engage their youth in such conversations, potentially placing them at risk for negative sexual health outcomes. Lack of caregiver–adolescent communication about sex may be particularly harmful for rural African American youth, as they often report early sex initiation and are disproportionately impacted by STIs. Moreover, sexual communication may be particularly challenging for families with strong religious backgrounds, potentially affecting the occurrence and breadth of topics covered during communication. Study aims were to: determine whether there was a relationship between caregiver religiosity and type of topics covered during communication about sex (e.g., general sexual health vs. positive aspects of sexuality) among 435 caregivers of early adolescent, African American youth; and if so, identify factors that might explain how religiosity affects communication about sex. Results indicated that caregiver religiosity was positively associated with communication about general, but not positive aspects of sexuality for caregivers of males. Attitudes towards communication about sex and open communication style mediated the relationship. There was no association between religiosity and communication about sex for caregivers of females. The findings from this study could provide a base to better understand and support the sexual socialization process within religious, African American families.     

Making Daddies into Fathers: Community-based Fatherhood Programs and the Construction of Masculinities for Low-income African American Men

In this analysis, we explore how low-income African American fathers build understandings of successful manhood in the context of community-based responsible fatherhood programs. Drawing on life history interviews with 75 men in Illinois and Indiana, we explore men’s attempts to fulfill normative expectations of fatherhood while living in communities with limited resources. We examine the efforts of community-based fatherhood programs to shape alternative African American masculinities through facilitation of personal turning points and “breaks with the past,” use of social support and institutional interventions, and the reframing of provision as a priority of successful fatherhood. We refer to Connell’s hegemonic masculinity framework (Connell in Masculinities, Polity Press, Cambridge, 1995) and discuss how both men and programs borrow from hegemonic and street masculinities to develop alternative approaches to paternal involvement for marginalized men.     

Lack of sex differences in knowledge of, attitudes about, and behaviors related to substance use in adolescents in a sample of high school students in the Northeastern USA

As part of an ongoing investigation, data were collected on behaviors and attitudes about substance abuse and general knowledge about substances for high school students (N = 1,103) during the 2002-2003 and 2003-2004 academic years. In preliminary analyses no meaningful sex differences were found for type or frequency of use, attitudes about substance use, or knowledge about substances. Lack of meaningful sex differences were evident even when comparisons by sex group were made within this ethnic minority population as well as within school Grades 10, 11, and 12. It is suggested that being a boy or a girl may have little to do with the American middle-class adolescents' choice to use substances. Findings should be understood to suggest possible cohort effects.     

From Consumerism to Stewardship: The Troublesome Ambiguities of an Attractive Option1

Abstract : Problems with consumerism may lead Christians to project the idea of responsible stewardship as an alternative. But this would be highly problematic. Although a part of many American Christians’ experience, and apparently bolstered by the authority of Jesus himself, the construct resists normative theological definition. It is too closely allied in our culture with “the spirit of capitalism” and tends to re‐enforce secular understandings of private property. The construct stewardship, therefore, should be used sparingly, if at all, in church circles.     

Teaching About Racism: Pernicious Implications of the Standard Portrayal

Resonating with understandings prevalent among White Americans, psychologists tend to portray racism as a problem of individual prejudice rather than a systemically embedded phenomenon. An unintended consequence of this portrayal is to reproduce a narrow construction of racism as something that does not require energetic measures to combat. We describe 2 studies that provide support for this idea. Tutorials presented the topic of racism either as individual prejudice (standard condition) or as a systemic phenomenon embedded in American society (sociocultural condition). Results confirmed that perception of racism and (in Study 2) endorsement of antiracist policy were greater among participants in the sociocultural tutorial condition than among participants in the both the standard tutorial and no-tutorial control conditions. An ironic consequence of standard pedagogy may be to promote a modern form of scientific racism that understates the ongoing significance of racist oppression.     

The threat of logical inversion and our need for philosophical attention: from thought-expression to discourse and discussion

Thought-expressions are not simply good; instead, they become good for us when they make sense, empower action, and support health. From time to time, we may need to (re)consider the difference between thought-expression and discourse, or thought-expression that really makes sense, and the difference between discourse and discussion, or a discourse-situation that makes genuine agreement or disagreement possible for us. In this essay, I explore a problem that D. Z. Phillips and Randy Ramal have termed “logical inversion,” and I argue that wherever logical inversions have gained a foothold in our thought-expressions, they threaten to render us incapable of authentic discourse and discussion by ensuring that we misunderstand the understandings of others such that we deceive ourselves and others by picturing the knowledge and truth of our perspective against an unreal background of conceivable falsehoods which we have falsely attributed to the perspectives of others. Where this has taken place, practices of philosophical attention and conceptual clarification are needed to help us move from a situation of endless thought expression toward authentic discourse and discussion.     

Maternal prenatal stress and infant regulatory capacity in Mexican Americans

The early postpartum period lays important groundwork for later self-regulation as infants’ dispositional traits interact with caregivers’ co-regulatory behaviors to produce the earliest forms of self-regulation. Although emerging literature suggests that fetal exposure to maternal stress may be integral in determining child self-regulatory capacity, the complex pathways that characterize these early developmental processes remain unclear. The current study considers these complex, transactional processes in a low income, Mexican American sample. Data were collected from 295 Mexican American infants and their mothers during prenatal, 6- and 12-week postpartum home interviews. Mother reports of stress were obtained prenatally, and mother reports of infant temperament were obtained at 6 weeks. Observer ratings of maternal sensitivity and infant regulatory behaviors were obtained at the 6- and 12-week time points. Study results indicate that prenatal stress predicts higher levels of infant negativity and surgency, both of which directly or interactively predict later engagement in regulatory behaviors. Unexpectedly, prenatal stress also predicted more engagement in orienting, but not self-comforting behaviors. Advancing understandings about the nature of these developmental pathways may have significant implications for targets of early intervention in this high risk population.