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One goal of the scientific research enterprise is to improve the lives of individuals and the overall health of societies. This goal is achieved through a combination of factors, including the composition of research portfolios. In turn, this composition is determined by a variety of scientific and societal needs. The recent history of polio research highlights the complex relations between research policy, scientific progress and societal benefits. Here, we briefly review the circumstances leading to the possibility of eradication of poliovirus, evaluate the research environment that emerged following the introduction of a vaccine, and compare and contrast the current research framework with that for other infectious diseases. From this analysis, policy lessons with general applicability to scientific research are identified. The Center for Science, Policy, & Outcomes is a project of Columbia University in the City of New York, 1 Thomas Circle NW, Suite 1075, Washington, DC 20005, USA.  相似文献   

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In a recent article, DeCato (1993) posits a fundamental dichotomy between the Comprehensive System (Exner, 1986) Rorschach interpretation, which is based on group norms, and the Perceptanalytic System (Piotrowski, 1957), which advocates validating Rorschach microfacts against the behavior of the individual. Perspective can be gained on this issue by recognizing that these approaches are actually extremes on a continuum where interpretation gradually narrows from the general to the specific. Acknowledging the funnel-shaped character of Rorschach interpretive approaches tins implications for understanding, scoring, and teaching projective techniques.  相似文献   

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Gordon and Bonkovsky describe a disturbing case of research involving minors in their article "Family Dynamics and Children in Medical Research." As presented in the case, there is little doubt that the assent obtained from the children was inadequate for the proposed research and that the institutional review board (IRB) failed to assess sufficiently the risk-benefit ratio of the research to the child-subjects.  相似文献   

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Kalichman M 《Science and engineering ethics》2002,8(2):215-8; discussion 219-22
Ethical dilemmas are the result of conflicts between potential benefits or harms for two or more competing interests. Therefore, ethical decision-making implies a responsibility to identify those interests, harms, and benefits. For this purpose, researchers have responsibilities to the research, the subjects of research, other researchers, the institution, society, the environment, and self.  相似文献   

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Jacobs and Michaels (2001) have argued that increased precision in judgments of the viewing distance to a perceived event should be attributed in part to perceptual learning. They found that observers used feedback to attune to the appropriate information variables gradually. McConnell, Muchisky, and Bingham (1998) had found that observers used feedback to calibrate event-specific scaling coefficients, that the calibration of one type of event generalized to other types, and that calibration occurred suddenly. We argue that Jacobs and Michaels must be partially correct and that, in our experiments, both calibration and perceptual attunement were required for accurate and precise judgments.  相似文献   

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Linhares and Freitas (2010; LF) argue that experts use analogical or semantic similarity, similarities that are not available from direct surface representations. LF make their case using a critique of Chase and Simon (1973b) and the presentation of a few chess positions and examples from other domains. Their conclusion is that models such as CHREST (Gobet et al., 2001) and theories such as the chunking theory (Chase & Simon, 1973b) and the template theory ( [Gobet and Simon, 1996a] and [Gobet and Simon, 1996b]) are inadequate for dealing with these issues. They propose an alternative paradigm, which they call “experience recognition.” Although we find this issue an interesting one, the separation between pattern recognition and problem solving is a lot more complex than LF portray. We instead suggest that a “revolution” in our to date successful modelling is not necessary. Especially in the chess domain, LF’s examples do not make the point they claim. Furthermore, their criticisms of CS are incorrect, and they have failed to mention a large number of experimental results that have supported the hypothesis of location-specific encodings. Although we agree that experts use semantic information and similarities, these ideas already possess analogues in CHREST, which can form the basis of further evolution of the theory.  相似文献   

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