Incidental cue learning in rats

Continuity theories of discrimination learning appear to say that animals learn equally about all cues impinging upon their receptors; noncontinuity theories that they learn about only one cue at a time. Experiment I showed that neither of these positions is correct: rats trained to attend to one cue learned less about a subsequently introduced incidental cue than rats given no such pretraining; but attention to one cue did not totally prevent learning about the other. A second experiment established that if rats are trained with one cue, and a second cue is then also made relevant, the amount learned about this second cue varies directly with (a) the abruptness with which it is introduced, and (b) the difficulty of the original discrimination.     

A latent class unfolding model for analyzing single stimulus preference ratings

A multidimensional unfolding model is developed that assumes that the subjects can be clustered into a small number of homogeneous groups or classes. The subjects that belong to the same group are represented by a single ideal point. Since it is not known in advance to which group of class a subject belongs, a mixture distribution model is formulated that can be considered as a latent class model for continuous single stimulus preference ratings. A GEM algorithm is described for estimating the parameters in the model. The M-step of the algorithm is based on a majorization procedure for updating the estimates of the spatial model parameters. A strategy for selecting the appropriate number of classes and the appropriate number of dimensions is proposed and fully illustrated on some artificial data. The latent class unfolding model is applied to political science data concerning party preferences from members of the Dutch Parliament. Finally, some possible extensions of the model are discussed.The first author is supported as Bevoegdverklaard Navorser of the Belgian Nationaal Fonds voor Wetenschappelijk Onderzoek. Part of this paper was presented at the Distancia meeting held in Rennes, France, June 1992.     

Taste/tactile cue discriminations in taste-aversion learning foIIowing depletion of noradrenaIine

Four experiments were performed to investigate the effect of noradrenaline (NA) depletion, following systemic DSP4 treatment, upon a tastehactile discrimination in taste-aversion learning. In Experiments 1 and 2 , noisy bottle (A) + lithium chloride pairings were alternated with saccharin (B) + saline pairings, and vice versa, during Phase I conditioning. The particular order of reinforcement presentation in each case was then reversed, so that a noisy bottle (A) + saline pairing was now altered with a saccharin (B) + lithium chloride pairing, etc., during Phase II (reversal) conditioning. In Experiments 3 and 4 , saccharin in noisy bottle (AB) + lithium chloride pairings alternated with either noisy bottle (A) + saline or saccharin (B) + saline pairings, and vice versa, during Phase I conditioning; the order of reinforcement presentation was then reversed, as above. None of the four experiments performed offered any evidence of impairments of the discrimination task as a result of NA depletion. These results are discussed in the context of associative preparedness and of discrimination learning in operant tasks and recent findings on compound conditioning, following the loss of NA.     

Social preference in rats

Rats were given repeated choices between social and nonsocial outcomes, and between familiar and unfamiliar social outcomes. Lever presses on either of 2 levers in the middle chamber of a 3-chamber apparatus opened a door adjacent to the lever, permitting 45-s access to social interaction with the rat in the chosen side chamber. In Experiment 1, rats preferred (a) social over nonsocial options, choosing their cagemate rat over an empty chamber, and (b) an unfamiliar over a familiar rat, choosing a non-cagemate over their cagemate. These findings were replicated in Experiment 2 with 2 different non-cagemate rats. Rats preferred both non-cagemate rats to a similar degree when pitted against their cagemate, but were indifferent when the 2 non-cagemates were pitted against each other. Similar preference for social over nonsocial and non-cagemate over cagemate was seen in Experiment 3, with new non-cagemate rats introduced after every third session. Response rates (for both cagemate and non-cagemate rats) were elevated under conditions of nonsocial (isolated) housing compared to conditions of social (paired) housing, demonstrating a social deprivation effect. Together, the experiments contribute to an experimental analysis of social preference within a social reinforcement framework, drawing on methods with proven efficacy in the analysis of reinforcement more generally.     

A room with a cue: personality judgments based on offices and bedrooms

The authors articulate a model specifying links between (a) individuals and the physical environments they occupy and (b) the environments and observers' impressions of the occupants. Two studies examined the basic phenomena underlying this model: Interobserver consensus, observer accuracy, cue utilization, and cue validity. Observer ratings based purely on offices or bedrooms were compared with self- and peer ratings of occupants and with physical features of the environments. Findings, which varied slightly across contexts and traits, suggest that (a) personal environments elicit similar impressions from independent observers, (b) observer impressions show some accuracy, (c) observers rely on valid cues in the rooms to form impressions of occupants, and (d) sex and race stereotypes partially mediate observer consensus and accuracy. Consensus and accuracy correlations were generally stronger than those found in zero-acquaintance research.     

A note on cue probability learning: what conditioning data reveal about cue contrast

In a probabilistic learning task with two complementary cues (C₁ and C₂) and two events (E₁ and E₂) the subject has a tendency to infer that E₂ will occur when C₂ occurs after he/she has observed that E₁ frequently goes with C₁. This phenomenon was termed cue contrast because it reflects the belief that C₂ contrasts with C₁ and should indicate E₂. Two kinds of predictions following from the notion of cue contrast were tested on response proportions from the first block of trials in four previously published experiments on cue probability learning. Of a total of 15 independent observations (eight within-group comparisons; seven between-group comparisons) 13 confirmed the predictions (sign test, p<0.005). It was concluded that cue utilization is both an inductive process based on association between cues and events and an inferential process based on contrast.     

Statistical inference based on latent ability estimates

The quality of approximations to first and second order moments (e.g., statistics like means, variances, regression coefficients) based on latent ability estimates is being discussed. The ability estimates are obtained using either the Rasch, or the two-parameter logistic model. Straightforward use of such statistics to make inferences with respect to true latent ability is not recommended, unless we account for the fact that the basic quantities are estimates. In this paper true score theory is used to account for the latter; the counterpart of observed/true score being estimated/true latent ability. It is shown that statistics based on the true score theory are virtually unbiased if the number of items presented to each examinee is larger than fifteen. Three types of estimators are compared: maximum likelihood, weighted maximum likelihood, and Bayes modal. Furthermore, the (dis)advantages of the true score method and direct modeling of latent ability is discussed.     

Estrogen abolishes latent inhibition in ovariectomized female rats

Estrogen is frequently prescribed as a method of birth control and as hormone replacement therapy for post-menopausal women with varied effects on cognition. Here the effects of estrogen on attention were examined using the latent inhibition (LI) behavioral paradigm. Ovariectomized (OVX) female rats were given either estrogen benzoate (EB, 10 or 100 microg/ml/kg; SC) or sesame oil vehicle. Males and OVX females receiving vehicle displayed normal LI. In contrast, LI was abolished in OVX females receiving EB. The lack of LI in OVX females receiving EB was a result of low suppression ratios, reflecting strong conditioning between the tone and the shock in these subjects even if they were pre-exposed to the tone. Thus, estrogen impaired the ability of OVX females to ignore irrelevant stimuli. Since different cognitive tasks vary in their required ability to ignore irrelevant stimuli, these results may account for some of the variations in the current literature on estrogen and cognition.     

Saline preference in rats determined by contingent licking

The albino rat's preference for .1 molar NaCl solution when paired with distilled water was measured using a lick contingent method. The method precluded position bias and revealed some fluid-deprivation influences in the resulting measured preference. Rats were trained to lick at a drinking tube containing water in order to obtain another tube containing the saline solution, under several levels of water deprivation. When tube contents were varied, the patterns of licking varied concurrently. Preference data was collected at low levels of fluid deprivation. It was shown that the saline solution was the primary controlling stimulus.     

Ingestive behavior in rat pups is modified by maternal sodium depletion

Developmental programming by maternal stress during pregnancy is found to influence behavioral development in the offspring. The main objective of this study was to investigate the effect of maternal sodium depletion in rats during pregnancy on the development of thirst mechanisms in the offspring. Pregnant rats underwent 3 episodes of saline depletion, induced by injecting sc 10 mg of Furosemide in saline (0.5 ml). The treatment, given on the 14th, 17th and 20th days post-conception, is thought to induce acute sodium depletion on dams. The offspring were tested for their drinking responses to Isoproterenol (500 μg/kg sc). In accordance to the known sequence of ontogenic development of drinking mechanisms, all groups of pups drunk after being stimulated with Isoproterenol at 6 days of age. The offspring from Furosemide-treated dams drank significantly less than the control group after Isoproterenol (p<0.001). Nevertheless, basal intake (water drunk after vehicle-saline only) was also significantly lower in these pups (p<0.001). In conclusion, offspring exposed to saline depletion in utero, modify their thirst responses at 6 day of age. This confirms that in utero conditions determine thirst responses in the offspring and they could provide adaptive advantages.     

Distractor effect on the latent inhibition of conditioned flavor aversion in rats

Using a conditioned flavor aversion procedure with rats as subjects, the effect of the addition of a distractor stimulus on the magnitude of the latent inhibition effect was examined. Experiment 1 showed that latent inhibition to vinegar was attenuated by the addition of sucrose during preexposure. On the other hand, sucrose added during conditioning to vinegar did not attenuate latent inhibition. It was also found that the degree of latent inhibition to the vinegar-sucrose compound solution was less when vinegar alone was preexposed (i.e., when sucrose was added only during conditioning) than when the compound solution was preexposed (i.e., when sucrose was added both during preexposure and during conditioning). Experiment 2 gave similar results but with sucrose assigned as the target flavor and vinegar as the distractor. These findings are in full agreement with the generalization decrement account of latent inhibition.