Beyond positive or negative: variability in daily parent-adolescent interaction quality is associated with adolescent emotion dysregulation

Previous work on the contribution of family environments to adolescent emotion dysregulation has tended to focus on broad parenting characteristics (such as warmth); however, it is possible that day-to-day variability in parenting may also relate to emotion dysregulation. The current study sought to test whether inconsistency in the quality of daily parent-youth interactions related to multiple indices of emotion dysregulation in adolescents. Two-hundred-twenty-two adolescents (ages 13–16; 53% female) participated with one parent. Adolescents completed 14-days of diary reporting on the quality of interactions with their parent (negative/neutral/positive) and their emotion dysregulation experiences for each day. Analyses reveal that, beyond the effects of average interaction quality, adolescents with greater variability in the quality of their interactions with their parent reported greater average emotion dysregulation across the days of diary recording and demonstrated greater variability in their ratings of daily emotion dysregulation. Findings were not accounted for by parental warmth or hostility, parent-reported trait-level emotion regulation, or day-level associations between study variables. In these ways, greater variability – and not merely greater negativity – during interactions between parents and adolescents was related to adolescent emotion dysregulation, suggesting that consistency in parent–adolescent relationships may be an important dimension of psychosocial risk to consider within families.     

Associations between serotonin transporter gene promoter region (5-HTTLPR) polymorphism and gaze bias for emotional information

The serotonin transporter promoter region polymorphism (5-HTTLPR) is associated with neural response to negative images in brain regions involved in the experience of emotion. However, the behavioral implications of this sensitivity have been studied far less extensively. The current study used eye-tracking methodology to examine how individuals genotyped for the 5-HTTLPR, including the single nucleotide polymorphism (SNP) rs25531, allocated attention during prolonged (30-s) exposure to face stimuli depicting positive and negative emotion. Short 5-HTTLPR allele carriers and carriers of the long allele with guanine at the sixth nucleotide (S/LG) displayed a stronger gaze bias (total fixation time, number of fixations, mean fixation length) for positive than for sad, threat, or neutral stimuli. In contrast, those homozygous for the long 5-HTTLPR allele with adenine at the sixth nucleotide (LA) viewed the emotion stimuli in an unbiased fashion. Time course analyses indicated no initial 5-HTTLPR group differences; however, S/LG 5-HTTLPR allele carriers were more likely than LA 5-HTTLPR homozygotes to direct gaze toward happy than toward sad stimuli over time. This bias toward positive stimuli during the later stages of information processing likely reflects a strategic effort to downregulate heightened reactivity to negative stimuli among 5-HTTLPR S/LG allele carriers.     

注意偏向训练对广泛性焦虑障碍负性情绪注意偏向的影响

采用改良的点探测任务,探讨了注意偏向训练能否改变GAD患者的负性情绪注意偏向并缓解其焦虑状态,及注意偏向训练的作用机制。结果发现,与控制组相比,训练组被试的负性注意偏向分数显著降低,具体表现为训练后训练组的负性注意解除能力显著高于控制组,两组被试的负性注意警觉在前后测均未有显著变化;注意偏向训练引起了GAD患者积极情绪的变化,缓解了状态焦虑。这证明了注意偏向训练对改变GAD患者负性情绪注意偏向及缓解其焦虑状态的有效性,并揭示这种改变主要是通过提升其对负性刺激的注意解除能力来实现的。     

Eye movements reveal mechanisms underlying attentional biases towards threat

Mechanisms underlying attentional biases towards threat (ABTs), such as attentional avoidance and difficulty of disengagement, are still unclear. To address this issue, we recorded participants' eye movements during a dot detection task in which threatening or neutral stimuli served as peripheral cues. We evaluated response times (RTs) in trials where participants looked at the central fixation cross (not at the cues), as they were required, and number and duration of (unwanted) fixations towards threatening or neutral cues; in all analyses trait anxiety was treated as a covariate. Difficulty in attentional disengagement (longer RTs) was found when peripheral threatening stimuli were presented for 100?ms. Moreover, we observed significantly shorter (unwanted) fixations on threatening than on neutral peripheral stimuli, compatible with an avoidance bias, for longer presentation times. These findings demonstrate that, independent of trait anxiety levels, disengagement bias occurs without eye movements, whereas eye movements are implied in threat avoidance.     

Anxiety sensitivity and attentional bias to threat interact to prospectively predict anxiety

The purpose of the present study was to examine anxiety sensitivity, attentional bias to threat (ABT), and the aggregate influence of these constructs as prospective predictors of anxiety. Participants (N = 176) completed a baseline assessment session which included the completion of self-report measures of anxiety and anxiety sensitivity, as well as an eye-tracking task in which eye movements were recorded during the viewing of neutral and threat images. Measures of anxiety and anxiety sensitivity were completed again as part of an online questionnaire battery at a 1-year follow-up session. As predicted, baseline anxiety sensitivity and ABT predicted anxiety at 1-year follow-up even after accounting for baseline anxiety. However, these main effects were qualified by a significant interaction effect such that those high in anxiety sensitivity at baseline reported relatively higher anxiety at the 1-year follow-up, but only if they also exhibited higher levels of ABT at baseline. Results suggest that individuals with this combination of vulnerability factors (high levels of both anxiety sensitivity and ABT) may be at particularly high risk for developing anxiety and may benefit from preemptive efforts to reduce ABT.     

高焦虑个体对威胁性刺激的注意偏向特点*

采用点探测实验范式,将图片按照威胁性分为高威胁性和一般威胁性,探讨焦虑程度不同的个体对不同威胁性刺激的注意特点。采用状态-特质焦虑问卷从265个大学生中选取了33名高焦虑被试和31名对照组被试。结果发现：（1）高焦虑组个体对一般威胁性刺激有显著注意偏向,对高威胁性刺激有注意回避趋势;（2）对照组个体对一般威胁性刺激没有表现出注意偏向,对高威胁刺激有注意偏向趋势。结论：（1）即使是一般威胁性图片也能引起高焦虑被试的注意偏向 （2）高威胁性图片才能引起对照组个体产生注意偏向的趋势。     

高低强迫清洗倾向个体对负性情绪注意偏向的差异

摘 要 本研究采用返回抑制范式,以诱发厌恶、恐惧和中性情绪的图片为线索,考察高、低强迫清洗倾向个体对负性情绪刺激注意偏向的差异及其发生机制。结果表明：（1）被试对诱发厌恶和恐惧的图片均产生了注意偏向且注意偏向是由注意解除困难所引起;（2）被试对诱发厌恶图片的注意偏向程度显著大于对诱发恐惧图片的注意偏向程度;（3）高、低强迫清洗倾向个体对诱发厌恶和恐惧图片的注意偏向程度之间的组间差异均不显著。     

Covert and overt orienting of attention to emotional faces in anxiety

Attentional biases for emotional faces were investigated in high, medium, and low anxiety groups (N = 54) using a probe detection task. Four types of facial expression (threat, sad, happy, neutral) were used to examine the specificity of the bias. Attentional bias measures were derived from manual reaction times (RTs) to probes and the direction of initial eye movement (EM) to the faces. The RT data indicated enhanced vigilance for threat rather than neutral faces in high and medium, but not low, state anxiety. The bias for negative faces appeared to be a combined function of stimulus threat value and the individual's anxiety level. The RT bias did not seem to depend on overt orienting, as many participants made few EMs. However, those who made frequent EMs to the faces showed concordance between the RT and EM bias measures, and so the RT measure of attentional bias for negative versus positive faces at 500 ms appears to provide a valid index of the direction of initial orienting to emotional stimuli. There was no evidence of an anxiety - related bias for happy faces (predicted by the emotionality hypothesis), nor a dysphoria - related bias for sad faces. However, increased dysphoria scores were associated with reduced attentiveness to happy faces.     

Attentional biases and memory for emotional stimuli in men and male rhesus monkeys

We examined attentional biases for social and non-social emotional stimuli in young adult men and compared the results to those of male rhesus monkeys (Macaca mulatta) previously tested in a similar dot-probe task (King et al. in Psychoneuroendocrinology 37(3):396–409, 2012). Recognition memory for these stimuli was also analyzed in each species, using a recognition memory task in humans and a delayed non-matching-to-sample task in monkeys. We found that both humans and monkeys displayed a similar pattern of attentional biases toward threatening facial expressions of conspecifics. The bias was significant in monkeys and of marginal significance in humans. In addition, humans, but not monkeys, exhibited an attentional bias away from negative non-social images. Attentional biases for social and non-social threat differed significantly, with both species showing a pattern of vigilance toward negative social images and avoidance of negative non-social images. Positive stimuli did not elicit significant attentional biases for either species. In humans, emotional content facilitated the recognition of non-social images, but no effect of emotion was found for the recognition of social images. Recognition accuracy was not affected by emotion in monkeys, but response times were faster for negative relative to positive images. Altogether, these results suggest shared mechanisms of social attention in humans and monkeys, with both species showing a pattern of selective attention toward threatening faces of conspecifics. These data are consistent with the view that selective vigilance to social threat is the result of evolutionary constraints. Yet, selective attention to threat was weaker in humans than in monkeys, suggesting that regulatory mechanisms enable non-anxious humans to reduce sensitivity to social threat in this paradigm, likely through enhanced prefrontal control and reduced amygdala activation. In addition, the findings emphasize important differences in attentional biases to social versus non-social threat in both species. Differences in the impact of emotional stimuli on recognition memory between monkeys and humans will require further study, as methodological differences in the recognition tasks may have affected the results.     

Health anxiety,anxiety sensitivity,and attentional biases for pictorial and linguistic health‐threat cues

The study investigated attentional biases for pictorial and linguistic health‐threat stimuli in high and low health anxious individuals, who were selected from the upper and lower quartile ranges of a normal sample using a screening measure of health anxiety. Attentional bias was assessed using a visual probe task which presented health‐threat and neutral pictures and words at two exposure durations, 500 ms and 1250 ms. The prediction that the high health anxious group would show a greater attentional bias for health‐threat cues than the low health anxious group was not supported despite the groups being well‐differentiated on a general measure of health anxiety, the Illness Attitudes Scale (IAS). Instead, the results indicated that individuals with high levels of anxiety sensitivity showed a significantly greater initial attentional bias for threat pictures compared with those with low anxiety sensitivity, as assessed by the Anxiety Sensitivity Index (ASI).     

面孔表情和声音情绪信息整合对返回抑制的影响

返回抑制(inhibition of return, IOR)与情绪刺激都具有引导注意偏向、提高搜索效率的特点, 但二者间是否存在一定的交互作用迄今为止尚不明确。研究采用“线索-目标”范式并在视听双通道呈现情绪刺激来考察情绪刺激的加工与IOR的交互作用。实验1中情绪刺激以单通道视觉面孔或一致的视听双通道呈现, 实验2通过在视听通道呈现不一致的情绪刺激进一步考察视听双通道情绪一致刺激对IOR的影响是否是由听觉通道一致的情绪刺激导致的, 即是否对听觉通道的情绪刺激进行了加工。结果发现, 视听双通道情绪一致刺激能够削弱IOR, 但情绪不一致刺激与IOR之间不存在交互作用, 并且单双通道的IOR不存在显著差异。研究结果表明仅在视听双通道呈现情绪一致刺激时, 才会影响同一阶段的IOR, 这进一步支持了IOR的知觉抑制理论。     

对威胁刺激的注意偏向：注意定向加速还是注意解除困难？

对威胁刺激的注意偏向普遍存在。注意定向加速和注意解除困难在不同阶段对注意偏向产生影响。威胁刺激属性、呈现时间以及被试特征是重要的调节因素。以杏仁核为核心的杏仁核?前扣带回网络可能是注意定向加速的神经基础, 而以眶额叶为中心的前额叶皮层可能是注意解除的神经基础。未来还需要就注意定向加速与注意解除困难的关系、注意偏向的调节机制以及其神经基础做更深入的研究。     

Selective attention and avoidance on a pictorial cueing task during stress in clinically anxious and depressed participants

Although it is well established that attentional biases exist in anxious populations, the specific components of visual orienting towards and away from emotional stimuli are not well delineated. The present study was designed to examine these processes. We used a modified spatial cueing task to assess the speed of engagement and disengagement from supraliminal and masked pictorial cues depicting threat, dysphoria, or neutral content in 36 clinically anxious, 41 depressed and 41 control participants. Participants were randomly assigned to a stress or neutral condition. During stress, anxious participants were slow to disengage from masked left hemifield pictures depicting threat or dysphoria, but were quick to disengage from supraliminal threat pictures. Information processing in anxious participants during stress was characterized by early selective attention of emotional stimuli, occurring prior to full conscious awareness, followed by effortful avoidance of threat. Depressed participants were distinct from the anxious group, displaying selective attention for stimuli depicting dysphoria, but not threat, during the neutral condition. In sum, attentional biases in clinical populations are associated with difficulties in the disengagement component of visual orienting. Further, a vigilant-avoidant pattern of attentional bias may represent a strategic attempt to compensate for the early activation of a fear response.     

Mindful attention predicts greater recovery from negative emotions,but not reduced reactivity

This study investigated the role of dispositional mindful attention in immediate reactivity to, and subsequent recovery from, laboratory-induced negative emotion. One hundred and fourteen undergraduates viewed blocks of negative pictures followed by neutral pictures. Participants’ emotional responses to negative pictures and subsequent neutral pictures were assessed via self-reported ratings. Participants’ emotional response to negative pictures was used to index level of emotional reactivity to unpleasant stimuli; emotional response to neutral pictures presented immediately after the negative pictures was used to index level of emotional recovery from pre-induced negative emotion (residual negativity). Results indicated that mindful attention was not associated with the emotional response to negative pictures, but it was associated with reduced negative emotion in response to the neutral pictures presented immediately after the negative pictures, suggesting better recovery as opposed to reduced reactivity. This effect was especially pronounced in later experimental blocks when the accumulation of negative stimuli produced greater negative emotion from which participants had to recover. The current study extends previous findings on the relationship between dispositional mindfulness and reduced negative emotion by demonstrating that mindful attention may facilitate better recovery from negative emotion, possibly through more effective disengagement from previous stimuli.     

Emotion processing effects on interference resolution in working memory

The interaction between emotion and working memory maintenance, load, and performance has been investigated with mixed results. The effect of emotion on specific executive processes such as interference resolution, however, remains relatively unexplored. In this series of studies, we examine how emotion affects interference resolution processes within working memory by modifying the Recency-probes paradigm (Monsel, 1978) to include emotional and neutral stimuli. Reaction time differences were compared between interference and non-interference trials for neutral and emotional words (Studies 1 & 3) and pictures (Study 2). Our results indicate that trials using emotional stimuli show a relative decrease in interference compared with trials using neutral stimuli, suggesting facilitation of interference resolution in the former. Furthermore, both valence and arousal seem to interact to produce this facilitation effect. These findings suggest that emotion facilitates response selection amid interference in working memory.     

Attentional bias during emotional processing: evidence from an emotional flanker task using IAPS

Attention is biased towards threat-related stimuli. In three experiments, we investigated the mechanisms, processes, and time course of this processing bias. An emotional flanker task simultaneously presented affective or neutral pictures from the international affective picture system database either as central response-relevant stimuli or surrounding response-uninformative flankers. Participants’ response times to central stimuli was measured. The attentional bias was observed when stimuli were presented either for 1500?ms (Experiment 1) or 500?ms (Experiment 2). The threat-related attentional bias held regardless of the stimuli competing for attention even when presentation time was further reduced to 200?ms (Experiment 3). The results indicate that automatic and controlled mechanisms may interact to modulate the orientation of attention to threat. The data presented here shed new light on the mechanisms, processes, and time course of this long investigated by still largely unknown processing bias.     

Disentangling the facilitating and hindering effects of threat-related stimuli – A visual search study

Although large body of research has demonstrated the attention-grabbing nature of threat-related stimuli, threat could also facilitate attentional processes. Previous studies suggest a linear relationship between the facilitating effect of the arousal level conveyed by threat and performance on visual search tasks. Due to the temporal competition bias favouring stimuli with higher arousal level, this could be more pronounced for shorter onset times. Here, through two experiments we aimed to disentangle the two effects by using a visual search paradigm that allowed us to separate the emotional stimuli and the cognitive task. We manipulated stimulus onset time and threat intensity. Participants saw neutral and threatening pictures as priming stimuli, and then, they had to find numbers in ascending order in a matrix array. We measured the reaction time for finding the first number, and search time for finding all the numbers. Our results showed that when the priming stimulus is presented, longer threatening pictures produced longer reaction times compared to neutral ones, which was reversed with increase in arousal. We did not find any significant effects for the shorter onset time. Further theoretical and methodological implications are discussed.     

Selective orienting of attention to masked threat faces in social anxiety

The aims of the study were two-fold: to examine whether previous evidence of a pre-attentive bias for masked threat faces in anxious individuals could be replicated, and to assess the relationship between the predicted bias and measures of trait and social anxiety. Pairs of face stimuli were briefly displayed and masked in a modified version of the visual probe task. Results indicated that high anxious individuals were faster to respond to probes occurring in the spatial location of masked threat rather than neutral faces; consistent with their attention being automatically captured by sub-threshold threat cues. Furthermore, this vigilance effect for masked threat faces appeared to be primarily a function of social anxiety and social avoidance, rather than trait anxiety. It was also more apparent when threat faces were presented in the left visual field, suggestive of right hemisphere involvement.     

Threat-relevance impairs executive functions: negative impact on working memory and response inhibition

The effects of emotional stimulus content on attention are well-known. In contrast, the impact of emotional information on higher executive control functions is undetermined. To elucidate the role of negative emotion in cognitive control, 56 adult female participants performed a combined working memory and response inhibition task, with threat-relevant (spider and snake) and neutral (flower and mushroom) stimuli. Threat-relevant stimuli impaired performance, by causing prolonged response times to working memory items and increased response inhibition error rate relative to neutral stimuli. The impaired response inhibition was only evident when threat-relevant stimuli co-occurred with working memory matches, in line with a common resource pool view of executive functions and emotion processing. Individual differences in reported fear of spiders were associated with differences of inhibitory control, while fear of snakes was associated with impaired overall accuracy on working memory trials. The results are discussed in relation to the dual-competition framework for interaction between executive functions and emotion (Pessoa, 2009).     

An experimental investigation of emotion dysregulation in borderline personality disorder

Despite the prominent role of emotion dysregulation in theoretical accounts of borderline personality disorder (BPD), few studies have examined emotion dysregulation in BPD. This study extends extant research by providing an experimental investigation of emotion dysregulation among outpatients with BPD. Specifically, this study modified an experimental measure of distress tolerance to examine differences between outpatients with BPD (n = 17) and those without a personality disorder (n = 18) in 2 aspects of emotion dysregulation: (a) the unwillingness to experience emotional distress in order to pursue goal-directed behavior and (b) the inability to engage in goal-directed behavior when distressed. As hypothesized, BPD participants were less willing to experience distress in order to pursue goal-directed behavior. However, BPD participants did not evidence greater difficulties engaging in goal-directed behavior when distressed. Results highlight directions for future research and suggest that particular aspects of emotion dysregulation may be more or less relevant to BPD.