Deviant ERP response to spoken non-words among adolescents exposed to cocaine in utero

Concern for the impact of prenatal cocaine exposure (PCE) on human language development is based on observations of impaired performance on assessments of language skills in these children relative to non-exposed children. We investigated the effects of PCE on speech processing ability using event-related potentials (ERPs) among a sample of adolescents followed prospectively since birth. This study presents findings regarding cortical functioning in 107 prenatally cocaine-exposed (PCE) and 46 non-drug-exposed (NDE) 13-year-old adolescents.PCE and NDE groups differed in processing of auditorily presented non-words at very early sensory/phonemic processing components (N1/P2), in somewhat higher-level phonological processing components (N2), and in late high-level linguistic/memory components (P600).These findings suggest that children with PCE have atypical neural responses to spoken language stimuli during low-level phonological processing and at a later stage of processing of spoken stimuli.     

Impact of mother interactive style on infant affect among babies exposed to alcohol in utero

This study examined the ability of infants prenatally exposed to alcohol to regulate their affect during and after a stressor. Specifically, the Still‐Face Paradigm (Tronick, Als, Adamson, Wise, ' Brazelton, 1978) was used as a stress induction paradigm to assess both mother‐infant interaction and infant self‐regulation. In addition to the mothers' interactive style, the effect of mothers' drinking during and after pregnancy on the infant was explored. Participants were 76 six‐month‐old infants and their mothers. Infant affect and maternal interaction style was coded second‐by‐second for the 6 min of the Still‐Face Paradigm. Results indicated that infants whose mothers made fewer attempts at engaging them during the play portion of the still‐face (e.g., either watched their infant or paid minimal attention to their infant) showed greater negative affect in contrast to infants whose mothers played in an interactive manner. A gender effect was found among female infants. That is, female infants whose mothers drank more during pregnancy showed greater negative affect. The study demonstrates the possibility of early identification of negativity in infants with prenatal alcohol exposure. The impact of mother‐child relationship on emotional regulation of infants prenatally alcohol exposed may be a target of future intervention and further study.     

Group exercise reduces depression in obese women without weight loss

Given participation in a 6-mo. exercise and relaxation training 8 obese women showed significant change in scores on the Beck Depression Inventory over the 6-mo. interval, but not on Body Mass Index or Medical Outcome Study Short-Form-36.     

Visuospatial working memory in school-aged children exposed in utero to cocaine.

OBJECTIVE: Among the neurocognitive impairments reported as associated with prenatal cocaine exposure, slower response time, and less efficient learning in school-aged children are common to findings from several laboratories. This study presents performance data on a spatial working memory task in 75 prenatally cocaine exposed (CE) and 55 nondrug-exposed (NDE) 8- to 10-year-old children. METHODS: Children were administered a novel neuropsychological measure of immediate- and short-term memory for visuospatial information, the Groton Maze Learning Test (GMLT), a computer-based hidden maze learning test that consists of a "timed chase test" (a simple measure of visuomotor speed), eight learning trials followed by a delayed recall trial after an 8-minute delay and a reverse learning trial. Performance is expressed as correct moves per second and number of errors per trial. RESULTS: Across all trials, the cocaine-exposed group showed significantly slower correct moves per second and made significantly more errors. There were no significant main effects for amounts of alcohol, tobacco, or marijuana exposure. After an 8-minute delay and compared to the eighth trial, cocaine-exposed children showed less consolidation in learning compared to nonexposed children. When asked to complete the maze in reverse, cocaine-exposed children showed a greater decrement in performance (decreased correct moves per second and increased errors) compared to the eighth learning trial. CONCLUSIONS: Children exposed in utero to cocaine exhibit a possible impairment in procedural learning and diminished efficiency in creating and accessing an internal spatial map to master the hidden maze.     

Behavior of neonates exposed in utero to methadone as assessed on the Brazelton scale

Twenty-nine infants exposed in utero to methadone and 37 comparison infants were examined on the Neonatal Behavioral Assessment Scale at early and late neonatal ages. All infants were full-term at birth, over 2500 g, and not yet circumcised at the early assessment. None of the methadone-exposed infants were breast-fed or were being treated pharmacologically for withdrawal. During the first week of life, methadone-exposed neonates differed from comparison ones in motoric behavior. Relative to comparison-group infants, they were jerkier and more tremulous, tense, active, and better able to put hand in mouth. By the end of the first month these differences diminished, although there was still a tendency for the methadone-exposed infants to have elevated body tonus. Neither perinatal complications, birth weight, nor sex of infant could explain the early neonatal differences between the methadone and comparison groups. Past the early stage of acute withdrawal, neonates exposed prenatally to methadone behave not unlike their nonexposed peers.     

Responses to collective risk: Appraisal and coping among workers exposed to occupational health hazards

Appraisals of occupational health risks and coping alternatives were examined in a study of 670 steelworkers. Three forms of coping were considered: emotion focused, problem focused, and system oriented. Path analysis was used to test a model of coping as a function of primary appraisals of occupational exposures, secondary appraisals of coping options, reappraisal of health concerns, and background characteristics. Results show that each element in the proposed model contributes significantly to all three coping types. In addition, distinctive patterns of secondary appraisal were observed for each type of coping. Future use of the concept of system-oriented coping is suggested for investigating problems not easily solved by individual action.     

Changing eating behaviour vs. losing weight: the role of goal focus for weight loss in overweight women

A 6-week longitudinal study with N?=?126 overweight women participating in a weight-loss programme investigated the hypothesis that focusing on the process (dietary behaviours) rather than on the outcome of dieting (weight loss) is associated with more successful goal pursuit and achievement. As expected, process focus was related positively to subjective daily success in dieting as well as to actual weight loss, and negatively to deviations from the diet. In contrast, outcome focus had a negative impact on successful dieting: focusing on weight loss was marginally negatively related to actual weight loss and was associated with more disinhibition after lapses. Confirming hypotheses, self-regulation failure (i.e. deviations from the diet, disinhibition) was negatively related to daily affective well-being. Contrary to hypotheses, however, goal focus was not directly associated with affective well-being but only indirectly through self-regulation. Focusing on the process rather than on the outcome of dieting, then, might help achieving difficult health-related goals and support self-regulation but does not contribute directly to affective well-being.     

N-of-1 study of weight loss maintenance assessing predictors of physical activity,adherence to weight loss plan and weight change

Objective: Behaviour change interventions are effective in supporting individuals to achieve clinically significant weight loss, but weight loss maintenance (WLM) is less often attained. This study examined predictive variables associated with WLM.

Design: N-of-1 study with daily ecological momentary assessment combined with objective measurement of weight and physical activity, collected with wireless devices (Fitbit?) for six months. Eight previously obese adults who had lost over 5% of their body weight in the past year took part. Data were analysed using time series methods.

Main outcomes measures: Predictor variables were based on five theoretical themes: maintenance motives, self-regulation, personal resources, habits, and environmental influences. Dependent variables were: objectively estimated step count and weight, and self-reported WLM plan adherence.

Results: For all participants, daily fluctuations in self-reported adherence to their WLM plan were significantly associated with most of the explanatory variables, including maintenance motivation and satisfaction with outcomes, self-regulation, habit, and stable environment. Personal resources were not a consistent predictor of plan adherence.

Conclusion: This is the first study to assess theoretical predictions of WLM within individuals. WLM is a dynamic process including the interplay of motivation, self-regulation, habit, resources, and perceptions of environmental context. Individuals maintaining their weight have unique psychological profiles which could be accounted for in interventions.     

Planning to lose weight: randomized controlled trial of an implementation intention prompt to enhance weight reduction among overweight and obese women.

OBJECTIVE: The trial investigates the effects of augmenting an established weight-reduction intervention with implementation intention prompts. DESIGN: Fifty-five overweight or obese women (ages 18 to 76 years; body mass index from 25.28 to 48.33) enrolled in a commercial weight reduction program were randomly assigned to either an implementation intention prompt or a control condition. Data were collected twice, with a time gap of 2 months. MAIN OUTCOME MEASURES: The primary outcome was participants' change in weight and body mass index from preintervention to follow-up. RESULTS: Repeated measures analysis of variance revealed a significant Time = Condition interaction: On average, implementation intention prompt participants lost 4.2 kg (95% confidence interval = 3.19, 5.07), whereas control participants lost 2.1 kg (95% confidence interval = 1.11, 3.09). The change in frequency of planning mediated the effects of the intervention on weight and body mass index change. CONCLUSION: Among obese or overweight women participating in a commercial weight loss program, those who learn to form implementation intentions can achieve greater weight reduction. Planning facilitation is a key mechanism explaining enhanced weight loss generated by implementation intention formation.     

The impact of self-efficacy on behavior change and weight change among overweight participants in a weight loss trial.

Despite considerable clinical interest, attempts to link perceived self-efficacy with successful weight control have had mixed success. Definitive data on prospective associations between self-efficacy and weight loss are particularly sparse. This study examined relationships between self-efficacy beliefs, weight control behaviors, and weight change among individuals participating in a weight loss trial (N = 349, 87% women). Cross-sectionally, eating and exercise self-efficacy beliefs were strongly associated with corresponding weight loss behaviors. Self-efficacy beliefs prospectively predicted weight control behavior and weight change during active treatment but not during follow-up. Mediational models indicate that people's weight control behaviors mediate the impact of self-efficacy on weight change.     

Self-rated competence, current weight, and body-image among college women

125 female undergraduates (M age = 19.7 yr.) self-rated their academic, social, and psychological competence and were assessed with respect to current weight, weight concern, and body attitudes. Self-rated academic, social, and psychological competence were not related to current weight; however, less positive self-evaluations of social competence were related to weight concern, negative appraisals of appearance, and dissatisfaction with body parts. Subjective ratings of academic and psychological competence were not significantly associated with any of these variables.     

Impaired performance of children exposed in utero to cocaine on a novel test of visuospatial working memory

The present study examines the potentially harmful effects of prenatal cocaine exposure on later visuospatial memory functions. A novel neuropsychological measure of immediate- and short-term memory for visuospatial information was administered to 40 children, who were identified as cocaine-exposed, and 11 age and socioeconomic status matched controls (all children were 8-9 years old). The Groton Maze Learning Test is a computer-based hidden maze learning test that consists of a 'timed chase test' (a simple measure of visuomotor speed), 5 learning trials on a hidden maze, followed by a delayed recall trial after an 8 min delay. The specific test parameters are chosen based on the age cohort of the subjects. The cocaine-exposed group performed significantly slower on the 'timed chase test,' the last 3 learning trials, and the delayed recall trial (p < or = .05 for all comparisons). Although there was a modest trend for the cocaine-exposed group to make more errors throughout the learning trials, there were no significant group differences. These results suggest that children who were exposed in utero to cocaine exhibit slowed visuomotor speed, a possible impairment in procedural learning, and diminished efficiency in accessing and using the internal spatial map that subjects create to master the maze.     

Value self-confrontation as a method to aid in weight loss

The impact on weight loss of an adaptation of the Rokeach (1973) value self-confrontation method was investigated in a field experiment. This method confronts people who have ranked their own values with information about the value priorities that discriminate between a positive and a negative reference group. A preliminary study revealed that successful weight losers differ from unsuccessful weight losers in valuing "wisdom" more than "happiness." Eighty-seven overweight adults were randomly assigned to one of three conditions: value self-confrontation, group discussion, or non-treatment control. Value self-confrontation subjects lost more weight than the other subjects over 2 months, and this weight loss persisted for an additional year. Changes in value priorities during the first 2 months suggest that weight loss was mediated by an increase in the importance attributed to wisdom relative to happiness. Implications for the theory of value-behavior relations and for practical application in weight loss programs are discussed.     

Attributes of successful approaches to weight loss and control

Most weight loss treatments result in only temporary losses, followed by slow regain. This paper examines those factors that are correlated with the most favorable results in terms of loss and maintenance of loss. Weight loss is positively related to self-monitoring, goal setting, social support, and length of treatment. Maintenance of weight loss is correlated with regular physical activity, self-monitoring, and continued contact with therapists. Regain is associated with inconsistent and restrictive dieting, life stress, negative coping style, and emotional or binge eating patterns. The implications drawn from these findings are (a) normalize eating patterns, (b) emphasize exercise, (c) ensure social support, (d) set realistic goal weights, (e) focus on health rather than appearance, (f) focus on self-esteem, and (g) target binge eating.     

Perceived calorie intake and state body-image satisfaction in women attempting weight loss: A preliminary investigation

State body-image satisfaction levels (BIS) can be predicted by appearance concerns, eating attitudes and body mass index (BMI). Determinants of state BIS and its variability were examined in women attempting weight loss. Little is known about contextual cues that influence state BIS; therefore the effect of eating on BIS was examined. Forty-six females attending a commercial weight loss group completed measures of shape and weight concerns, appearance beliefs and dietary restraint, followed by completion of a diary that assessed state BIS, mood and perceived calorie intake immediately following evening meals. Regression analysis indicated that after controlling for mood, state BIS was associated with higher BMI and dietary restraint. Greater variability in state BIS was associated with greater variability in perceived calorie intake. This relationship was fully mediated by greater variability in mood. The findings imply that state BIS warrants investigation as a process that may influence weight loss management.     

The differential importance of weight and body image among college men and women

Among a sample of American college students, body image and the degree of desired weight change were associated with academic self-rankings, with social and psychological well-being, and with the development of eating difficulties. The effects of body image and desired weight change on eating disorders were generally found to be greater for women than for men, and their effects on student self-rankings of academic ability, social, and psychological traits were more pervasive for women than for men. The less attractive a woman perceived herself to be and the more weight she wanted to lose, the greater was her overall sense of academic, social, and psychological impairment. Women who had poor body images and who desired to lose weight were more likely to report eating difficulties.     

Biases in orienting and maintenance of attention among weight dissatisfied women: an eye-movement study

Despite evidence indicating fatness and thinness information are processed differently among weight-preoccupied and eating disordered individuals, the exact nature of these attentional biases is not clear. In this research, eye movement (EM) tracking assessed biases in specific component processes of visual attention (i.e., orientation, detection, maintenance and disengagement of gaze) in relation to body-related stimuli among 20 weight dissatisfied (WD) and 20 weight satisfied young women. Eye movements were recorded while participants completed a dot-probe task that featured fatness-neutral and thinness-neutral word pairs. Compared to controls, WD women were more likely to direct their initial gaze toward fatness words, had a shorter mean latency of first fixation on both fatness and thinness words, had longer first fixation on fatness words but shorter first fixation on thinness words, and shorter total gaze duration on thinness words. Reaction time data showed a maintenance bias towards fatness words among the WD women. In sum, results indicated WD women show initial orienting, speeded detection and initial maintenance biases towards fat body words in addition to a speeded detection – avoidance pattern of biases in relation to thin body words. In sum, results highlight the importance of the utility of EM-tracking as a means of identifying subtle attentional biases among weight dissatisfied women drawn from a non-clinical setting and the need to assess attentional biases as a dynamic process.     

A summer day camp approach to adolescent weight loss

Twenty-five overweight adolescents completed a summer weight loss day camp program on the Stanford University campus. All participants attended camp four days per week for four hours to learn and practice eating and exercise skills conducive to weight loss. Parents met weekly to discuss the program content and to explore their role in their adolescent's weight management. At posttreatment, reductions were achieved in weight, percent overweight, and skinfold, with greater changes observed for the eight-week group than for the four-week group. Improvements were also evident in participants' self-reported habits and knowledge of weight management concepts. Parent and participant assessment of the camp experience was very positive. The results of the summer weight loss day camp suggest that an intensive program of eating and exercise habit instruction, practice, and monitoring, which allows the participants to remain in the home setting, may provide benefits not found in other more traditional approaches to adolescent weight loss.