Changes in frontal and posterior cortical activity underlie the early emergence of executive function

Executive function (EF) is a key cognitive process that emerges in early childhood and facilitates children's ability to control their own behavior. Individual differences in EF skills early in life are predictive of quality‐of‐life outcomes 30 years later (Moffitt et al., 2011). What changes in the brain give rise to this critical cognitive ability? Traditionally, frontal cortex growth is thought to underlie changes in cognitive control (Bunge & Zelazo, 2006; Moriguchi & Hiraki, 2009). However, more recent data highlight the importance of long‐range cortical interactions between frontal and posterior brain regions. Here, we test the hypothesis that developmental changes in EF skills reflect changes in how posterior and frontal brain regions work together. Results show that children who fail a “hard” version of an EF task and who are thought to have an immature frontal cortex, show robust frontal activity in an “easy” version of the task. We show how this effect can arise via posterior brain regions that provide on‐the‐job training for the frontal cortex, effectively teaching the frontal cortex adaptive patterns of brain activity on “easy” EF tasks. In this case, frontal cortex activation can be seen as both the cause and the consequence of rule switching. Results also show that older children have differential posterior cortical activation on “easy” and “hard” tasks that reflects continued refinement of brain networks even in skilled children. These data set the stage for new training programs to foster the development of EF skills in at‐risk children.     

A one-year follow-up of the cognitive and psycho-behavioural skills in artistic gymnastics

A good set of cognitive and psycho-behavioural skills are beneficial for young athletes to overcome and benefit from developmental challenges. Unfortunately, there is still a dearth of knowledge on how both these cognitive (i.e., executive functions; EF) and psycho-behavioural (i.e., psychological characteristics of developing excellence; PCDE) skills develop in youth athletes. Especially for athletes in early specialisation sports such as artistic gymnastics, the early EF and PCDE development might be important to be able to cope with the pressure and challenges that comes with a transition to the next stage. In the current study, artistic gymnasts between 9 and 22 years old were tested twice with a 12-month interval to investigate the changes in EF and PCDE. Results showed that EF developed within the youngest stage, but plateaued at the later stages. Most PCDE did not seem to change over time within each stage. Furthermore, the transition to a new stage does not seem to coincide with an increased improvement of PCDE. However, with a case study approach in the oldest stages, still inter-individual differences in EF and PCDE scores over time were observed. This study shows that EF and PCDE develop over time, albeit in a non-linear way, and along a variety of developmental trajectories.     

Fonctions exécutives et théorie de l’esprit chez le jeune enfant : une relation réciproque ?

The aim of this study was to assess the specific relation between 18-month-olds’ performance on tasks measuring language skills, executive function (EF) and theory of mind (ToM). The ToM tasks included measures of intention and false-belief understanding whereas working memory and inhibitory control were assessed with three EF tasks. Expressive vocabulary was assessed with the MacArthur Communicative Development Inventory. The main findings showed that both aspects of ToM are strongly linked at this age to inhibitory control, but not to working memory abilities. Language skills were not associated with either ToM or EF abilities. With regard to inter-tasks coherence within EF and ToM, we replicated previous findings with no consistency across EF tasks but an association between false-belief and intention understanding. Overall, these findings provide evidence for a link between executive function and theory of mind at the youngest age ever tested. They also challenge the view that EF is not required to succeed on the false-belief task based on spontaneous responses.     

From terrible twos to sassy sixes: The development of vocabulary and executive functioning across early childhood

Across the early childhood period of development, young children exhibit considerable growth in their executive functioning (EF) and vocabulary abilities. Understanding the developmental trajectory of these seemingly interrelated processes is important as both early vocabulary and EF have been shown to predict critical academic and socio-emotional outcomes later in childhood. Although previous research suggests that EF and vocabulary are correlated in early childhood, much of the existing longitudinal research has focused on unidirectional relations among preschool child samples. The current large-scale study, therefore, sought to examine whether children's vocabulary and EF abilities are bidirectionally related over time across four measurement waves in early childhood (i.e., at ages 2, 3, 4, and 6). At each timepoint, children's vocabulary skills were positively correlated with their concurrent EF abilities. After controlling for child sex and maternal education status, the best-fitting, cross-lagged panel model was a unidirectional model whereby children's early vocabulary scores predicted their later EF performance at each timepoint. Although age 2 EF significantly predicted age 3 vocabulary size, this association was no longer significant after accounting for maternal education status. Our results illustrate that vocabulary size plays an important role in predicting children's later EF performance across various timepoints in early childhood, even after controlling for children's initial EF scores. These findings have important implications for intervention research as fostering early vocabulary acquisition may serve as a possible avenue for improving EF outcomes in young children.

Research Highlights

• Children's vocabulary size is positively correlated with their concurrent executive functioning skill at ages 2, 3, 4, and 6
• Young children's early vocabulary scores predict their later EF performance across measurement waves, even after controlling for initial EF skill
• There is stability in children's relative vocabulary size and executive functioning performance over time in early childhood

     

Old dogs learning new tricks: Neuroplasticity beyond the juvenile period

Twenty years ago, the prevalent view in Psychology was that although learning and the formation of new memories are lifelong occurrences, the neural changes associated with these events were all in the existing receptors. No new neural hardware, from synapses to neurons, was thought to appear after a protracted period early in life. In the past 20 years, another view has supplanted this one, showing that although the juvenile period is especially suited to neuroplastic adaptation, there is hard neuroplastic change later in life as well. We review a selection of evidence for this view from both animal and human models, showing how it reflects three principles of neuroplasticity: (1) earlier and later experience-induced changes to neuroarchitecture differ in degree more so than in type; (2) the types of experiences that lead to neuroplastic change narrow with age; and (3) differences in the amenability of neural circuitry to change result from basic differences in neuroarchitecture and neuroenvironment in different phases of development.     

Demographic and familial predictors of early executive function development: Contribution of a person-centered perspective

Executive function (EF) skills are integral components of young children’s growing competence, but little is known about the role of early family context and experiences in their development. We examined how demographic and familial risks during infancy predicted EF competence at 36 months of age in a large, predominantly low-income sample of nonurban families from Pennsylvania and North Carolina in the United States. Using latent class analysis, six ecological risk profiles best captured the diverse experiences of these families. Profiles with various combinations of family structure, income, and psychosocial risks were differentially related to EF. Much of the influence of early risks on later EF appears to be transmitted through quality of parent-child interactions during infancy. Findings suggest that early family environments may prove to be especially fruitful contexts for the promotion of EF development.     

A Longitudinal Assessment of Executive Function Skills and Their Association with Math Performance

The present study was designed to examine both concurrent and predictive associations between scores on a measure of executive function (EF) skills, the Contingency Naming Test (CNT), during the early school-age years. A secondary aim of the study was to examine the association between EF skills and mathematics performance. We administered tests of mathematics ability, and the CNT, to 178 children at ages 6 to 7, 8 to 9, and 10 to 11 years. From the CNT we obtained measures of response fluency/efficiency, working memory, and inhibition. The results demonstrate main effects of age on all CNT measures of EF, as anticipated, and inconsistent main effects of gender or mathematics learning disability status. Rates of improvement in EF varied as a function of the working memory demands present during a given task. There were differences in concurrent and predictive correlations for different CNT performance measures. EF scores obtained during the first assessment were as strongly associated with each other as they were with EF scores obtained four years later, suggesting a moderately stable source of individual differences on cognitive performance. EF scores at age 6 to 7 years were associated with concurrent and later mathematics scores, and most of these correlations were stronger than the significant associations found between response fluency on a baseline task (with no working memory demand) and mathematics performance. These findings have implications for the stability of EF skills during the school-age years, and the role of EF in early and later elementary school mathematics performance.     

A longitudinal assessment of executive function skills and their association with math performance.

The present study was designed to examine both concurrent and predictive associations between scores on a measure of executive function (EF) skills, the Contingency Naming Test (CNT), during the early school-age years. A secondary aim of the study was to examine the association between EF skills and mathematics performance. We administered tests of mathematics ability, and the CNT, to 178 children at ages 6 to 7, 8 to 9, and 10 to 11 years. From the CNT we obtained measures of response fluency/efficiency, working memory, and inhibition. The results demonstrate main effects of age on all CNT measures of EF, as anticipated, and inconsistent main effects of gender or mathematics learning disability status. Rates of improvement in EF varied as a function of the working memory demands present during a given task. There were differences in concurrent and predictive correlations for different CNT performance measures. EF scores obtained during the first assessment were as strongly associated with each other as they were with EF scores obtained four years later, suggesting a moderately stable source of individual differences on cognitive performance. EF scores at age 6 to 7 years were associated with concurrent and later mathematics scores, and most of these correlations were stronger than the significant associations found between response fluency on a baseline task (with no working memory demand) and mathematics performance. These findings have implications for the stability of EF skills during the school-age years, and the role of EF in early and later elementary school mathematics performance.     

Associations between risk factors,developmental outcomes,and executive function in neonatal intensive care unit graduates at 2 years: A retrospective study

This study explores the extent to which medical and sociodemographic variables and cognitive and language skills are associated with executive function (EF) skills in neonatal intensive care unit (NICU) graduates at 24 months of adjusted age. We explored cognitive, language, and EF skills in 42 NICU graduates who participated in a NICU follow-up programme clinic. The association between risk factors and EF and the completion of the EF assessment were explored. Correlational analyses revealed that child gender was associated with EF scores. Analyses revealed cognitive skills, language skills, and multiple gestational births were associated with EF assessment completion. Our findings are among the first to examine EF skills in NICU graduates as young as 24 months of age using a multidimensional, child completed measure. Implications for NICU follow up programmes, the consideration of early interventions aimed to positively affect EF skills, and considerations for future studies are discussed.     

Factor structure of the Behavior Rating Inventory of Executive Functions (BRIEF-P) at age three years

The preschool period is an important developmental period for the emergence of cognitive self-regulatory skills or executive functions (EF). To date, evidence regarding the structure of EF in preschool children has supported both unitary and multicomponent models. The aim of the present study was to test the factor structure of early EF as measured by the Behavior Rating Inventory of Executive Function-Preschool version (BRIEF-P). BRIEF-P consists of five subscales and three broader indexes, hypothesized to tap into different subcomponents of EF. Parent ratings of EF from a nonreferred sample of children recruited from the Norwegian Mother and Child Cohort Study (N = 1134; age range 37–47 months) were subjected to confirmatory factor analyses (CFA). Three theoretically derived models were assessed; the second-order three-factor model originally proposed by the BRIEF-P authors, a “true” first-order one-factor model and a second-order one-factor model. CFA fit statistics supported the original three-factor solution. However, the difference in fit was marginal between this model and the second-order one-factor model. A follow-up exploratory factor analysis (EFA) supported the existence of several factors underlying EF in early preschool years, with a considerable overlap with the five BRIEF-P subscales. Our results suggest that some differentiation in EF has taken place at age 3 years, which is reflected in behavior ratings. The internal consistency of the BRIEF-P five clinical subscales is supported. Subscale interrelations may, however, differ at this age from those observed in the preschool group as a whole.     

Maternal Coping Skills as a Moderator Between Depression and Stressful Life Events: Effects on Children's Behavioral Problems in an Intervention Program

In this study, I report secondary analyses using data from the Infant Health and Development Program (IHDP). The IHDP included parent-targeted as well as child-targeted components as an integral part of early intervention programs. I examined three questions: (1) Do the IHDP early intervention services enhance adaptive maternal coping skills? (2) Do maternal coping skills moderate the relationship between stressful life events and maternal depression? (3) Are maternal coping skills associated with children's behavioral scores? Mothers in the treatment group have more adaptive coping skills than follow-up only mothers, and these effects are moderated by maternal characteristics. Adaptive coping skills moderate the effects of negative life events on maternal depression. Adaptive maternal coping skills are significantly associated with fewer behavioral problems for children at age three. These effects are moderated by the intervention. Implications for early intervention programs are discussed.     

Better early or late? Examining the influence of age of exposure and language proficiency on executive function in early and late bilinguals

Previous research has shown that early and late bilinguals differ in their language learning experiences and linguistic outcomes. However, evidence of differences between these bilinguals on measures of executive function (EF) has been mixed. As a result, the current study sought to (1) determine whether early and late bilinguals vary from one another and (2) exhibit cognitive advantages in EF relative to monolinguals. One hundred and five participants (42 monolinguals, 40 early bilinguals and 23 late bilinguals) completed the study. Participants' EF skills were assessed using the Auditorily Cued Number Numeral Task. Overall, the results did not reveal clear advantages for the early bilinguals compared to the two other groups. In fact, early bilinguals and monolinguals were equivalent in their performance on the EF task, whereas the late bilinguals were less accurate, relative to the other two groups. The differences in the performance of early and late bilinguals are discussed in terms of the competition model of second-language learning proposed in previous research. Taken together, these findings indicate that individual differences in EF influence the observed differences found in EF across language groups.     

The mediating role of joint attention in the relationship between motor skills and receptive and expressive language in siblings at risk for autism spectrum disorder

Language problems are highly prevalent in younger siblings of children with autism spectrum disorder (HR-sibs), yet little is known about early predictors. There is growing evidence that motor and language development are linked and this connection might be mediated by joint attention. Developmental changes in motor abilities change how children interact with objects and people (e.g., by showing), which may influence language development. This association has however not yet been studied in HR-sibs. The interrelationship between motor, joint attention and language skills was explored in younger siblings of typically developing children (LR-sibs, N = 31) and HR-sibs (N = 32). In both groups, motor skills (composite of fine and gross motor skills) at 10 months influenced receptive and expressive language at 36 months directly and indirectly through joint attention at 14 months. Group status moderated this direct and indirect effect with mainly significant effects in HR-sibs. This indicates that lower motor skills can have cascading effects on joint attention and language in HR-sibs. Consequently, assessment of early motor skills in HR-sibs might hold promise for early identification of motor difficulties but can also be indicative of language difficulties later in life, especially when difficulties with joint attention are also present.     

Verbal and nonverbal predictors of executive function in early childhood

The study of executive function (EF) has become increasingly popular in multiple areas of research. A wealth of evidence has supported the value of EF in shaping notable outcomes across typical and atypical development; however, little evidence has supported the cognitive contributors to early EF development. The current study used data from a large longitudinal sample of healthy children to investigate the differential influence of verbal and nonverbal cognition on later EF. Participants were assessed at 2 years of age using the Mullen Scales of Early Learning, and Mullen scores were used to calculate nonverbal and verbal developmental quotients. Executive function was measured at 6 years using assessments from the Stanford-Binet, Cambridge Neuropsychological Test Automated Battery, and the Behavior Rating Inventory of Executive Function. Results suggested that early nonverbal cognition was a better predictor of 6-year EF as measured by task-based laboratory assessments, whereas verbal cognition was a better predictor of parent-reported EF. Findings are discussed in regard to EF development and characteristics of EF measurement.     

Development of Different Forms of Skill Learning Throughout the Lifespan

The acquisition of complex motor, cognitive, and social skills, like playing a musical instrument or mastering sports or a language, is generally associated with implicit skill learning (SL). Although it is a general view that SL is most effective in childhood, and such skills are best acquired if learning starts early, this idea has rarely been tested by systematic empirical studies on the developmental pathways of SL from childhood to old age. In this paper, we challenge the view that childhood and early school years are the prime time for skill learning by tracking age‐related changes in performance in three different paradigms of SL. We collected data from participants between 7 and 87 years for (1) a Serial Reaction Time Task (SRT) testing the learning of motor sequences, (2) an Artificial Grammar Learning (AGL) task testing the extraction of regularities from auditory sequences, and (3) Probabilistic Category Learning in the Weather Prediction task (WP), a non‐sequential categorization task. Results on all three tasks show that adolescence and adulthood are the most efficient periods for skill learning, since instead of becoming less and less effective with age, SL improves from childhood into adulthood and then later declines with aging.     

The role of executive functioning in CBT: a pilot study with anxious older adults

Cognitive behavior therapy (CBT) is an effective treatment for late life anxiety and depression. The successful use of CBT is assumed to rely on cognitive skills known as executive functions (EF; e.g., hypothesis generation, allocation of attention, self-monitoring) governed by the prefrontal cortex. Because older adults sometimes have executive deficits as a consequence of normal aging, EF may be a mediator of CBT outcome in older samples. The current pilot study tested the hypothesis that older adults with executive deficits (as measured by neuropsychological tests) would show decreased therapeutic benefit from CBT for generalized anxiety disorder, as compared to a group with intact EF. Results indicated differential response to CBT within the dysfunction group depending on the stability (and possibly, the etiology) of executive deficits from pre- to posttreatment. Those whose EF scores remained low from pre- to posttreatment did not respond to CBT, while those whose scores improved responded quite well, similar to an Intact EF group. Results indicate that some, but not all, older adults with executive dysfunction show decreased benefit from CBT, and are consistent with the assumption that executive skills are important for the successful use of CBT. However, some participants may show improvement on both mood and cognitive skills during treatment, which is discussed further.     

Effects of foster care intervention and caregiving quality on the bidirectional development of executive functions and social skills following institutional rearing

Institutional rearing negatively impacts the development of children's social skills and executive functions (EF). However, little is known about whether childhood social skills mediate the effects of the foster care intervention (FCG) and foster caregiving quality following early institutional rearing on EF and social skills in adolescence. We examined (a) whether children's social skills at 8 years mediate the impact of the FCG on the development of EF at ages 12 and 16 years, and (b) whether social skills and EF at ages 8 and 12 mediate the relation between caregiving quality in foster care at 42 months and subsequent social skills and EF at age 16. Participants included abandoned children from Romanian institutions, who were randomly assigned to a FCG (n = 68) or care as usual (n = 68), and a never-institutionalized group (n = 135). At ages 8, 12, and 16, social skills were assessed via caregiver and teacher reports and EF were assessed via the Cambridge Neuropsychological Test Automated Battery. Caregiving quality of foster caregivers was observed at 42 months. FCG predicted better social skills at 8 years, which in turn predicted better EF in adolescence. Higher caregiver quality in foster care at 42 months predicted better social skills at 8 and 12 years, and better EF at 12 years, which in turn predicted 16-year EF and social skills. These findings suggest that interventions targeting caregiving quality within foster care home environments may have long-lasting positive effects on children's social skills and EF.     

Executive function and theory of mind: Predictive relations from ages 2 to 4

Despite robust associations between children's theory of mind (ToM) and executive function (EF) skills, longitudinal studies examining this association remain scarce. In a socially diverse sample of 122 children (seen at ages 2, 3, and 4), this study examined (a) developmental stability of associations between ToM, EF, verbal ability, and social disadvantage; (b) continuity and change in ToM and EF; and (c) predictive relations between ToM and EF. Verbal ability and social disadvantage independently predicted changes in EF (but not ToM). Task scores improved with age and showed stable individual differences. The authors examined predictive relations between ToM and EF using partial correlations (controlling for age and verbal ability) and hierarchical regressions (that also controlled for social disadvantage and initial ToM and EF). The findings provide only partial support for the view that ToM is a prerequisite for EF but stronger support for the proposal that EF facilitates children's performance on ToM tasks.     

Wittgenstein on the grounds of religious faith: A Kantian proposal

This paper argues that there is an important continuity between Wittgenstein's early remarks on religion and his later treatment of the theme as it appears in his lectures in the 1930s and in his personal diary notes at that time. This continuity pertains to 3 features. First, the early and later Wittgenstein share a critical stance on methodological naturalism, that is, the view that the method of philosophy is relevantly similar to that of the natural sciences. Importantly, religion figures as one of Wittgenstein's examples of the limits of the factual language of natural sciences. Second, both the early and the later Wittgenstein connect religion to the problem of seeing one's life as meaningful while denying the possibility of establishing any objectively understood meaning of life. Third, both evoke the idea of different types of judgments, the conditions of which are independent of each other. Although religious faith is not grounded in factual knowledge and cannot be justified by appeal to empirical evidence or conceptual argumentation, it is not groundless either. Rather, in accordance with Kant who claims that faith may have a nontheoretical justification, Wittgenstein shows that religious faith may result from a personal experience of one's life as a meaningful whole.     

Developmental aspects of trauma and traumatic aspects of development

In this paper I try to show that inherent in healthy development are emotional experiences that are the stuff of trauma. Failure to reintegrate these experiences means that they can serve as a resonating board for difficulties in later life, adding to their traumatic impact. Focusing on global changes that occur at the end of the first year, I exemplify these developments with an infant observation and show how a six-year-old boy's failure to integrate them contributed to his experiencing a normal life event as a trauma. I then offer clinical material from the analysis of a man to demonstrate how later life events resonated with early experience associated with this period. All are linked to a complex pattern of object relations I have come across clinically, whereby feelings of grief associated with an idealized object are split off from feelings of grievance against an object experienced as persecutory because of its perceived superior status.