An object-oriented simulation of a brain system underlying human aggression

Neural structures involved in aggression were incorporated into a model on the basis of neuro-anatomical data. A software program written in Smalltalk, the Brain Structure Simulator (Seguin, 1994) was used to simulate the effects of activity levels of different brain structures. Relationships among brain structures were then tested by changing activity levels of key structures. Results were consistent with research reports on the brain basis of aggression (Albert, Walsh, & Jonik, 1993; Pontius, 1984).     

Need-informational interaction of brain structures

The data presented deal with the role of four main brain structures in the development of emotional states and the organization of purposeful behavior. According to these data, the frontal neocortex orients behavior towards signals of highly probable events (reinforcement), whereas the hypothalamus is the basis for satisfaction of the dominant need. Unlike the neocortex, the hippocampus reacts to events of low probability, which is typical of emotionally stressed brain activity. Unlike the hypothalamus, the amygdala creates the balance, the dynamic coexistence, of competing needs (motivations) and emotions generated by such needs, which makes behavior more adequate. Individual characteristics of the interaction among the four brain structures is the basis for the individual types of higher nervous activity.     

Shadows of music-language interaction on low frequency brain oscillatory patterns

Electrophysiological studies investigating similarities between music and language perception have relied exclusively on the signal averaging technique, which does not adequately represent oscillatory aspects of electrical brain activity that are relevant for higher cognition. The current study investigated the patterns of brain oscillations during simultaneous processing of music and language using visually presented sentences and auditorily presented chord sequences. Music-syntactically regular or irregular chord functions were presented in sync with syntactically or semantically correct or incorrect words. Irregular chord functions (presented simultaneously with a syntactically correct word) produced an early (150-250 ms) spectral power decrease over anterior frontal regions in the theta band (5-7 Hz) and a late (350-700 ms) power increase in both the delta and the theta band (2-7 Hz) over parietal regions. Syntactically incorrect words (presented simultaneously with a regular chord) elicited a similar late power increase in delta-theta band over parietal sites, but no early effect. Interestingly, the late effect was significantly diminished when the language-syntactic and music-syntactic irregularities occurred at the same time. Further, the presence of a semantic violation occurring simultaneously with regular chords produced a significant increase in later delta-theta power at posterior regions; this effect was marginally decreased when the identical semantic violation occurred simultaneously with a music syntactical violation. Altogether, these results show that low frequency oscillatory networks get activated during the syntactic processing of both music and language, and further, these networks may possibly be shared.     

SIMPOLYCAT: An SAS program for conducting CAT simulation based on polytomous IRT models

A real-data simulation of computerized adaptive testing (CAT) is an important step in real-life CAT applications. Such a simulation allows CAT developers to evaluate important features of the CAT system, such as item selection and stopping rules, before live testing. SIMPOLYCAT, an SAS macro program, was created by the authors to conduct real-data CAT simulations based on polytomous item response theory (IRT) models. In SIMPOLYCAT, item responses can be input from an external file or generated internally on the basis of item parameters provided by users. The program allows users to choose among methods of setting initial ?, approaches to item selection, trait estimators, CAT stopping criteria, polytomous IRT models, and other CAT parameters. In addition, CAT simulation results can be saved easily and used for further study. The purpose of this article is to introduce SIMPOLYCAT, briefly describe the program algorithm and parameters, and provide examples of CAT simulations, using generated and real data. Visual comparisons of the results obtained from the CAT simulations are presented.     

MAOA基因与环境对反社会行为的交互作用及其可能的脑机制

反社会行为具有重要的遗传学基础。MAOA基因是反社会行为的重要候选基因,该基因与环境对反社会行为具有交互作用,然而其内在作用机制尚不清楚。与情绪管理相关的脑区和神经回路,以及与工作记忆能力相关的脑区和神经回路在其中起重要作用。未来研究可从多基因-环境交互作用、理论模型验证、脑结构与功能的中介作用等方面进一步深化MAOA基因与反社会行为的关系研究。     

Dichoptic interaction of visual structure and light flashes

Perceptual interaction between monocular flashes and different amounts of continuously visible target structure shown to the other eye was investigated. A response variable called dominance of the flashes is defined and found to be a direct function of flash intensity and an inverse function of contraocular target structure. The dominance variable is distinguished from subjective brightness of the flashes and subjective complexity of the targets. The observed effects are attributed to limited central processing capacity with increased informational load.     

Effect of auditory isolation on activity-based anorexia

The objective was to study male and female rats exposed to Activity-Based Anorexia (ABA; simultaneous exposition to food restriction and free access to an activity wheel) under two conditions of sound attenuation, by means of different arrangements of wheels (standard versus isolation) in the laboratory room. Regardless of the sound attenuation condition, all but one male and one female with access to wheels had to be removed from the experiment, but extended ABA endurance was found in rats in the sound attenuation condition. Furthermore, significantly lower levels of running were observed in both males and females under the sound attenuation arrangement in the isolation condition. The results suggest that external stimulation plays a role in the activity displayed by rats exposed to ABA, and that the reduction of external stimulation diminishes running but does not protect rats from developing ABA.     

ERP evidence on the interaction between information structure and emotional salience of words

Both emotional words and words focused by information structure can capture attention. This study examined the interplay between emotional salience and information structure in modulating attentional resources in the service of integrating emotional words into sentence context. Event-related potentials (ERPs) to affectively negative, neutral, and positive words, which were either focused or nonfocused in question_–answer pairs, were evaluated during sentence comprehension. The results revealed an early negative effect (90–200 ms), a P2 effect, as well as an effect in the N400 time window, for both emotional salience and information structure. Moreover, an interaction between emotional salience and information structure occurred within the N400 time window over right posterior electrodes, showing that information structure influences the semantic integration only for neutral words, but not for emotional words. This might reflect the fact that the linguistic salience of emotional words can override the effect of information structure on the integration of words into context. The interaction provides evidence for attention–emotion interactions at a later stage of processing. In addition, the absence of interaction in the early time window suggests that the processing of emotional information is highly automatic and independent of context. The results suggest independent attention capture systems of emotional salience and information structure at the early stage but an interaction between them at a later stage, during the semantic integration of words.     

Amygdala modulation of memory consolidation: interaction with other brain systems

There is a strong consensus that the amygdala is involved in mediating influences of emotional arousal and stress on learning and memory. There is extensive evidence that the basolateral amygdala (BLA) is a critical locus of integration of neuromodulatory influences regulating the consolidation of several forms of memory. Many drug and stress hormone influences converge in activating the release of norepinephrine (NE) within the BLA. Evidence from studies using in vivo microdialysis and high-performance liquid chromatography indicates that increases in amygdala NE levels assessed following inhibitory avoidance training correlate highly with subsequent retention. Other evidence indicates that NE influences on memory consolidation require muscarinic cholinergic activation within the BLA provided by projections from the nucleus basalis magnocellularis (NB). Evidence from several experiments indicates that activation of the BLA plays an essential role in modulating memory consolidation processes involving other brain regions. These findings provide strong support for the hypothesis that the BLA plays a critical role in regulating the consolidation of lasting memories of significant experiences.     

The experience of feeling fat for women with anorexia nervosa: An interpretative phenomenological analysis

Feeling fat has been implicated as a maintenance factor in anorexia nervosa (AN), despite limited research into the experience. This study expanded the literature by exploring the lived experience of feeling fat for women with a diagnosis of AN. Seven women participated in this study and data was collected through semi-structured interviews. Interpretive Phenomenological Analysis (IPA) was employed to explore the participants’ experience of ‘feeling fat’ and its relevance for clinical treatment. Four main themes emerged from the data: ‘negative sense of self’, ‘feeling out of control’, ‘coping with feeling fat’, and ‘making sense of feeling fat is complex’. These results highlight feeling fat as a significant experience and maintenance factor for women with a diagnosis of AN. Implications for addressing feeling fat within psychological therapy are explored.     

The interaction of payoff structure and regulatory focus in classification

This report brings together research on motivation and learning by exploring how fit of regulatory focus affects people's ability to acquire new categories. Perceptual categories were learned by people with a promotion focus (a situationally determined sensitivity to gains) or a prevention focus (a sensitivity to losses). Classification performance was closest to optimal (as determined by models fit to individual subjects' data) when the regulatory focus matched the structure of the payoffs for the categories. Promotion-focus subjects performed best when the payoffs consisted of all gains. Prevention-focus subjects performed best when the payoffs consisted of all losses.     

A program for the analysis of intragroup interaction based on spatial dynamics

This paper describes the salient features of a computer program used in the analysis of the activity of a group of long-tail macaques. The principal feature concerns the time variation of the separation of selected dyads, although individual activity is also summarized. The program has been written such that it is adaptable to any enclosed group of Ss.