Mood-congruent attention and memory bias in dysphoria: Exploring the coherence among information-processing biases

Recent studies indicate that depression is characterized by mood-congruent attention bias at later stages of information-processing. Moreover, depression has been associated with enhanced recall of negative information. The present study tested the coherence between attention and memory bias in dysphoria. Stable dysphoric (n = 41) and non-dysphoric (n = 41) undergraduates first performed a spatial cueing task that included negative, positive, and neutral words. Words were presented for 250 ms under conditions that allowed or prevented elaborate processing. Memory for the words presented in the cueing task was tested using incidental free recall. Dysphoric individuals exhibited an attention bias for negative words in the condition that allowed elaborate processing, with the attention bias for negative words predicting free recall of negative words. Results demonstrate the coherence of attention and memory bias in dysphoric individuals and provide suggestions on the influence of attention bias on further processing of negative material.     

Affective orientation influences memory for emotional and neutral words

Memory is better for emotional words than for neutral words, but the conditions contributing to emotional memory improvement are not entirely understood. Elsewhere, it has been observed that retrieval of a word is easier when its attributes are congruent with a property assessed during an earlier judgment task. The present study examined whether affective assessment of a word matters to its remembrance. Two experiments were run, one in which only valence assessment was performed, and another in which valence assessment was combined with a running recognition for list words. In both experiments, some participants judged whether each word in a randomized list was negative (negative monitoring), and others judged whether each was positive (positive monitoring). We then tested their explicit memory for the words via both free recall and delayed recognition. Both experiments revealed an affective congruence effect, such that negative words were more likely to be recalled and recognized after negative monitoring, whereas positive words likewise benefited from positive monitoring. Memory for neutral words was better after negative monitoring than positive monitoring.Thus, memory for both emotional and neutral words is contingent on one's affective orientation during encoding.     

Preserved word-stem-completion priming of semantically encoded information in Alzheimer's disease

Alzheimer's disease (AD) patients and normal elderly control subjects completed 80 standardized sentence frames with single words, yielding a measure of semantic memory. Memory for best fit sentence endings was then tested either explicitly, with a forced-choice recognition task, or implicitly, with a word-stem-completion task. The patients completed fewer sentences with best fit word endings than did the control subjects. Explicit retention was markedly defective in the AD group, but word-stem completion was normal. The preserved word-stem completion in AD is discussed in terms of encoding operations and transfer-appropriate processing.     

Acute alcohol effects on repetition priming and word recognition memory with equivalent memory cues

Acute alcohol intoxication effects on memory were examined using a recollection-based word recognition memory task and a repetition priming task of memory for the same information without explicit reference to the study context. Memory cues were equivalent across tasks; encoding was manipulated by varying the frequency of occurrence (FOC) of words in the study lists. Twenty-two female and male social drinkers (age 21-24 years) completed equivalent versions of the memory tasks in two counterbalanced sessions (alcohol challenge, no-alcohol). Alcohol and the FOC manipulation affected recollection-based memory processing, but not repetition priming. Results supported alcohol's dissociative effects on memory systems.     

Influences of emotion on context memory while viewing film clips

Participants listened to words while viewing film clips (audio off). Film clips were classified as neutral, positively valenced, negatively valenced, and arousing. Memory was assessed in three ways: recall of film content, recall of words, and context recognition. In the context recognition test, participants were presented a word and determined which film clip was showing when the word was originally presented. In two experiments, context memory performance was disrupted when words were presented during negatively valenced film clips, whereas it was enhanced when words were presented during arousing film clips. Free recall of words presented during the negatively valenced films was also disrupted. These findings suggest multiple influences of emotion on memory performance.     

The effect of divided attention on memory for items and their context.

Memory for context, in comparison to memory for items, is a more demanding task and requires more attentional resources. We examined differences between item and context memory using divided attention at encoding and retrieval. Participants were presented with word lists and were instructed to learn the items (i.e., words), the intrinsic context (i.e., the colour of the cards on which each word was presented), and the extrinsic context (i.e., the temporal order of the words). Among 72 young adults, in comparison to conditions of full attention, divided attention applied at encoding only or retrieval only resulted in equally lower performance on all memory tasks; in contrast, divided attention applied at both encoding and retrieval resulted in lower performance only on memory for temporal order. The findings support the idea that memory for temporal order requires greater attentional resources and strategic processing than memory for items.     

Cognitive processing of emotional information in depression, panic, and somatoform disorder

Emotional Stroop tasks (subliminal/supraliminal exposures), implicit memory tasks (tachistoscopic word identification), and explicit memory tasks (free recall after incidental learning) with 4 word types (physical threat, positive, negative, and neutral words) were administered to patients with major depressive disorder (n=30), panic disorder (n=33), somatoform disorder (n=25), and healthy control participants (n=33). On the Stroop task, panic patients showed subliminal interferences for physical threat and negative words, depressive patients showed supraliminal interferences for negative words, and somatoform patients showed supraliminal interferences for physical threat words. No patient groups demonstrated implicit memory biases. On the explicit memory task, depressive and panic patients showed memory biases for negative words; somatoform patients showed biases for physical threat words.     

Recognition memory of retrieved sequences of words

The subject was asked to retrieve words belonging to a given category, natural or artificially created. After n words were retrieved, a recognition task was given either immediately after or after a delay (4 hours, 7, 14, or 28 days). Several probe words were presented and the subject had to decide whether each had been retrieved or not. The length of retrieval sequence, n, was systematically varied. Results of three experiments showed that, in general, mean decision time was almost independent of n. Namely, recognition regarding self-generated lists of words seems to be due to a different information processing than recognition regarding lists of words presented by the experimenter to memorize. Implications of the findings for retrieval from long term memory were discussed.     

注意促进效应的ERP研究

近期发现,采用目标探测任务作为二级任务时,目标探测条件不仅不会削弱,甚至会提高记忆成绩,产生注意促进效应（ABE）。为进一步探究目标探测的作用机制,研究采用事件相关电位（ERP）技术,对比目标与分心条件在编码和提取过程中所诱发的ERP差异。结果表明,两类条件在再认过程中所诱发的ERP差异不仅表现在早期与知觉加工相关的ERP成份上,并且一直持续到了后期与细节提取相关的ERP成分上。由此推测,ABE不仅体现在编码早期的知觉加工阶段,更会延续到后期的复述与精加工。     

Divided attention and memory: evidence of substantial interference effects at retrieval and encoding

In 5 divided attention (DA) experiments, students (24 in each experiment) performed visual distracting tasks (e.g., recognition of words, word and digit monitoring) while either simultaneously encoding an auditory word list or engaging in oral free recall of the target word list. DA during retrieval, using either of the word-based distracting tasks, produced relatively larger interference effects than the digit-monitoring task. DA during encoding produced uniformly large interference effects, regardless of the type of distracting task. Results suggest that when attention is divided at retrieval, interference is created only when the memory and concurrent task compete for access to word-specific representational systems; no such specificity is necessary to create interference at encoding. During encoding, memory and concurrent tasks compete primarily for general resources, whereas during retrieval, they compete primarily for representational systems.     

Task-dependent modulation of word processing mechanisms during modified visual search tasks

During visual search for words, the impact of the visual and semantic features of words varies as a function of the search task. This event-related potential (ERP) study focused on the way these features of words are used to detect similarities between the distractor words that are glanced at and the target word, as well as to then reject the distractor words. The participants had to search for a target word that was either given literally or defined by a semantic clue among words presented sequentially. The distractor words included words that resembled the target and words that were semantically related to the target. The P2a component was the first component to be modulated by the visual and/or semantic similarity of distractors to the target word, and these modulations varied according to the task. The same held true for the later N300 and N400 components, which confirms that, depending on the task, distinct processing pathways were sensitized through attentional modulation. Hence, the process that matches what is perceived with the target acts during the first 200?ms after word presentation, and both early detection and late rejection processes of words depend on the search task and on the representation of the target stored in memory.     

Recall of morphologically complex forms is affected by memory task but not dyslexia

The authors studied the effect of morphological complexity on working memory in list recall tasks with base words (boy), inflected words (boy + 's) and derived words (boy + hood) in a morphologically rich language: Finnish. Simple serial recall was compared to complex working memory tasks, combining word recall with sentence verification in 8-year-old normally reading participants, dyslexic children, and adults. The normally reading children performed better than dyslexic children on both memory tasks and a test of morphology. Base words were better recalled than morphologically complex words. Memory was better for derived than inflected words in simple but not complex span tasks. There was no interaction between word type and reading group and thus no suggestion of dyslexia being associated with specific problems to represent complex morphology in working memory. Morphological processing in working memory appeared to depend on the task.     

Sub-chronic rolipram treatment leads to a persistent improvement in long-term object memory in rats

In the present study the effects of sub-chronic rolipram treatment in an object recognition task in 3-month-old male rats were investigated. Rats remember which object they have explored in a previous trial (T1) when they are tested 1 h later (T2). However, when tested 24 h later, they do not remember which object was presented to them in the first trial. Drug treatments may improve discrimination performance after 24 h, i.e., improve memory for the familiar object. Rats were sub-chronically treated with 0.5 mg/kg rolipram (p.o.) for five consecutive days and tested with a 24 h delay between T1 and T2. Memory performance in the object recognition task was assessed before, during and after sub-chronic treatment. In addition, we investigated whether the timing of the final dose, i.e., 24, 1, or 6 h before training, had an effect on memory performance. During sub-chronic treatment, i.e., after 2-3 days of rolipram treatment, moderate effects on memory performance were observed. Regardless of when the final administration was given, sub-chronic rolipram treatment improved long-term memory performance. Since plasma and brain rolipram levels were undetectable at 24 h before the test, and acute treatment with rolipram 24 h before training had no effects, the observed memory enhancement cannot be attributed to acute rolipram effects. The long-term memory enhancing effects of rolipram might be explained by long-lasting neuronal changes by the chronic treatment due to recurring activation of the cAMP/PKA/CREB pathway leading to CREB phosphorylation.     

防御性自尊大学生注意偏向对记忆偏向的影响

摘 要 为考查防御性自尊大学生注意偏向对记忆偏向的影响,本研究将被试分为训练组和控制组,训练组接受注意偏向训练,之后完成记忆任务。记忆任务中呈现中性和攻击性词汇,要求被试对词汇进行自由回忆。结果发现,控制组对攻击性信息存在着记忆偏向,而训练组对攻击性信息的记忆偏向消失。注意偏向训练可以即时性地改变防御性自尊大学生对攻击性信息的注意偏向,注意偏向可能是特质一致性记忆的原因之一。     

The role of controlled attention on recall in major depression

Information processing biases are hallmark features of major depressive disorder (MDD). Depressed individuals display biased memory and attention for negative material. Given that memory is highly dependent on attention for initial encoding, understanding the interplay of these processes may provide important insight into mechanisms that produce memory biases in depression. In particular, attentional control—the ability to selectively attend to task-relevant information by both inhibiting the processing of irrelevant information and disengaging attention from irrelevant material—may be one area of impairment in MDD. In the current study, clinically depressed (MDD: n = 15) and never depressed (non-MDD: n = 22) participants' line of visual gaze was assessed while participants viewed positive and negative word pairs. For each word pair, participants were instructed to attend to one word (target) and ignore one word (distracter). Free recall of study stimuli was then assessed. Depressed individuals displayed greater recall of negatively valenced target words following the task. Although there were no group differences in attentional control in the context of negative words, attention to negative targets mediated the relationship between depression status and recall of negative words. Results suggest a stronger link between attention and memory for negative material in MDD.     

Perceptual implicit memory requires attentional encoding

Perceptual implicit memory for previously attended and unattended words was measured either in a word-stem completion task or in a perceptual fluency (perceptual identification) task. Subjects (N = 144) first engaged in a focused attention task in which they were to identify one of two words presented for 100, 200, or 300 msec. Words were classified as attended if they were reported during the focused attention task and unattended if they were not. Results for both implicit memory tests indicated reliable perceptual implicit memory for attended words but not for unattended words, regardless of focused attention exposure duration. The results indicate that perceptual implicit memory tasks reflect attentional encoding processes; that is, words must undergo attentional encoding if they are to affect performance on a later perceptual implicit memory test.     

Effects of modality on the neural correlates of encoding processes supporting recollection and familiarity

Prior research has demonstrated that the neural correlates of successful encoding ("subsequent memory effects") partially overlap with neural regions selectively engaged by the on-line demands of the study task. The primary goal of the present experiment was to determine whether this overlap is associated solely with encoding processes supporting later recollection, or whether overlapping subsequent memory and study condition effects are also evident when later memory is familiarity-based. Subjects (N = 17) underwent fMRI scanning while studying a series of visually and auditorily presented words. Memory for the words was subsequently tested with a modified Remember/Know procedure. Auditorily selective subsequent familiarity effects were evident in bilateral temporal regions that also responded preferentially to auditory items. Although other interpretations are possible, these findings suggest that overlap between study condition-selective subsequent memory effects and regions selectively sensitive to study demands is not uniquely associated with later recollection. In addition, modality-independent subsequent memory effects were identified in several cortical regions. In every case, the effects were greatest for later recollected items, and smaller for items later recognized on the basis of familiarity. The implications of this quantitative dissociation for dual-process models of recognition memory are discussed.     

How arousal modulates memory: Disentangling the effects of attention and retention

Emotion may influence memory both by altering attention and perception during encoding and by affecting memory retention. To date, studies have focused on the enhancement of memory consolidation by arousal. However, they have failed to rule out a role for attention. To specifically link memory enhancement of arousing material to modulation of memory retention, we examined recognition of neutral and arousing words at two time points and under conditions that manipulate attention during encoding. Participants were briefly presented with an arousing or neutral word at the periphery, while fixating on a central word. Recognition of peripheral words was assessed either immediately or after 24 h. Whereas recognition of neutral words became worse over time, recognition of arousing words remained the same and was better than neutral word recognition at delay. The results indicate that arousal supports slower forgetting even when the difference in attentional resources allocated to stimuli is minimized.     

Visuospatial processing in memory for word location in writing

Two experiments examined how visuospatial processing engaged during text composition intervenes in memory for word location. Experiment 1 showed that in contrast to participants who performed a spatial task concurrently with composing a text, participants who performed a concurrent visual task recalled fewer word locations after the composition. Consequently, it is hypothesized that writers process the written text in order to visually represent its physical layout, and that this representation is then used when locating words. Experiment 2 tested this hypothesis by comparing a standard composition condition (with the written trace) with a condition in which the written trace was suppressed during composition, and with a condition without written trace and with added visual noise. Memory for word location only decreased with visual noise, indicating that construction of the visual representation of the text does not rely on the written trace but involves visual working memory.     

Improved segregation of simultaneous talkers differentially affects perceptual and cognitive capacity demands for recognizing speech in competing speech

Perception of speech in competing speech is facilitated by spatial separation of the target and distracting speech, but this benefit may arise at either a perceptual or a cognitive level of processing. Load theory predicts different effects of perceptual and cognitive (working memory) load on selective attention in flanker task contexts, suggesting that this paradigm may be used to distinguish levels of interference. Two experiments examined interference from competing speech during a word recognition task under different perceptual and working memory loads in a dual-task paradigm. Listeners identified words produced by a talker of one gender while ignoring a talker of the other gender. Perceptual load was manipulated using a nonspeech response cue, with response conditional upon either one or two acoustic features (pitch and modulation). Memory load was manipulated with a secondary task consisting of one or six visually presented digits. In the first experiment, the target and distractor were presented at different virtual locations (0° and 90°, respectively), whereas in the second, all the stimuli were presented from the same apparent location. Results suggest that spatial cues improve resistance to distraction in part by reducing working memory demand.