Orienting reaction habituation in chronic alcoholics

A polygraphic study on resistance to habituation of the somatic (EMG), autonomic (finger plethysmogram, galvanic skin reaction, respiration) and EEG (acoustic-evoked potential and EEG-blocking reaction) components of the orienting reaction elicited by a repetitive auditory stimulus was performed in 67 chronic alcoholics and in 70 matched normal subjects (control group). The study showed a significantly lower resistance to habituation of the orienting reaction in alcoholics than in normal control subjects. The severity of this habituation disturbance depended on the patients’ age, type of alcoholism, alcohol consumption intensity and chronicity, as well as the type of resting EEG.     

Retention of orienting reaction habituation in chronic alcoholics

A polygraphic study on resistance to habituation of the somatic (EMG), autonomic (finger plethysmogram, galvanic skin reaction, respiration) and EEG (acoustic-evoked potential and EEG-blocking reaction) components of the orienting reaction, elicited by a repetitive auditory stimulus during successive (weekly) sessions was performed in 67 chronic alcoholics and in 70 matched normal subjects (control group). The study showed significant retention disturbances of orienting reaction habituation (i.e., of learning), or the “saving” of stimulations, achieved from one session to the other to obtain the habituation criterion, the savings being less in alcoholics than in control subjects. The severity of habituation retention disturbances depended on patients’ ages, types of alcoholism, alcohol consumption intensity and chronicity, as well as the type of resting EEG.     

Retention of orienting reaction habituation in patients with postmeningoencephalitic epilepsy

A polygraphic study on habituation of the somatic, autonomic, and EEG components of the orienting reaction elicited by a repetitive auditory stimulus during successive (weekly) sessions was performed in 29 patients with postmeningoencephalic epilepsy (PME) and in 116 control subjects. The study evidenced significant retention disturbances of orienting reaction habituation (i.e., of learning), the “saving” of stimulation, achieved from one session to another to obtain the habituation criterion, being lesser in PME patients than in control subjects. The severity of habituation retention disturbances depended on seizure frequency, electroclinical form, and history, as well as on features of EEG tracings.     

Retention of orienting reaction habituation in patients with epileptogenic cerebral tumors

An electrographic study on habituation of the somatic (EMG), autonomic (finger plethysmogram, galvanic skin reaction, respiration, pulse) and EEG (acoustic evoked potential and EEG-blocking reaction) components of the orienting reaction elicited by a repetitive auditory stimulus during successive (weekly) sessions was performed in 41 patients with epileptogenic cerebral tumors (ECT) and in 128 control subjects. The study evidenced significant retention disturbances of orienting reaction habituation (i.e., of learning), the “saving” of stimulations, achieved from one session to the other to obtain the habituation criterion, being lesser in ECT patients than in control subjects. The severity of habituation retention disturbances depended on the tumor site and size, as well as on the electro-clinical form and frequency of seizures. Thus, the most marked habituation retention disturbances were found in patients with temporal or predominantly temporal epileptogenic tumors, in cases with large hemispheric epileptogenic tumors (over 6 cm), in patients with generalized or generalized plus partial seizures, as well as in those with frequent (daily) seizures.     

Orienting reaction in patients with multiple sclerosis

A polygraphic study of the somatic (EMG), autonomic (finger plethysmogram, galvanic skin reaction, respiration, pulse, and EEG (acoustic-evoked potential and EEG-blocking reaction) components of the orienting reaction elicited by an auditory stimulus was performed in 71 patients with multiple sclerosis and in 74 matched normal subjects (control group). The study showed a significantly less intense orienting reaction in patients with multiple sclerosis than in control normal subjects. The severity of this responsiveness disturbance depended on the patients’ age at symptom onset, major symptom types on admission, and the relapse frequency. The orienting reaction changes found in patients with multiple sclerosis may be ascribed to the diffuse demyelinating lesions in the nervous system of these patients, which generate, apart from the so polymorphous clinical manifestations of this disease, also important responsiveness disturbances.     

Effectiveness of “neutral,” habituated,shock-related,and food-related stimuli as CSs for avoidance learning in goldfish

Four groups of 11 goldfish were given different kinds of experiences with a light stimulus later to be used as a CS for two-way, active avoidance conditioning. For one group, the light was repeatedly paired with food; for another, the light was paired with inescapable shock; a third group received light-only presentations (habituation); a control group never experienced the light before testing. In avoidance conditioning testing, the shock-related and food-related groups performed significantly better than the control group, which in turn outperformed the habituated group. It is concluded that the acquisition of an orienting reaction to a CS outweighs the positive-vs-negative source of that OR.     

Overextinction of the orienting reaction

Sokolov’s 1963 report of return of the orienting reaction (OR) to repeated stimulus presentations following habituation was examined in 18 S’s using the galvanic skin response (GSR) component of the OR and an auditory stimulus of 60 db intensity and 1000 cps. Both group and individual S data analysis indicated a return of the OR which habituated quickly. The number of stimulus presentations to the OR return point showed an inverse relationship to rate of initial OR habituation for individual S’s.     

Orienting responses to pleasant stimuli when expecting pleasant or unpleasant events

The aim was to investigate further the effect of more vigorous orienting to stimuli denoting common fears than to neutral stimuli in subjects threatened with shock. In two experiments, orienting responses (ORs) to pleasant and to neutral words were compared. In Experiment I, the subjects were expecting shock and, in Experiment II, pleasant music. In neither experiment were there differences either in the magnitudes or in the habituation rates of the electrodermal ORs. For clarification, there should be control both of the subjective salience of the stimuli and also of the level of expectation.     

Cortical evoked potentials as indicators of auditory-visual cross-modal association in young adults

Auditory evoked potentials (AEPs) were studied from scalp locations Cz and Oz on 37 adults aged 20–22 years during sensori-sensorial association of a weak sound (S) and a strong flash of light (L). After sound alone repetition (habituation), S-L association modified AEP: first, it caused a generalized orienting response expressed as increasing of Cz and Oz amplitude AEPs. Then, this pattern gave way to an activation limited to the Oz lead: the increase of amplitude was then concomitant with shortened latencies when compared to sound-alone-habituated responses. Inter-individual differences were observed since these occipital modifications were recorded only on 26 subjects. The other 11 subjects did not exhibit any occipital modifications following S-L association. For them, the main modification was a strong decrease of Cz AEP induced by S-L association. These two groups also differed in their capacity to ignore irrelevent stimuli which is higher in the first group (AEP amplitude habituation with sound-alone repetition) than in the second one (no AEP habituation).     

A Review of: “The Mask of Shame: Stigma of Mental Illness and an Agenda for Change,by Steven P. Hinshaw”

This case report describes the successful treatment of a 5-year-old girl who, subsequent to an accident in which she received burns covering 30% of her body, experienced nightmares and night terrors as often as 15-20 times every night. In addition to the night terrors, she developed a strong phobic reaction to a wide range of fire-related stimuli. Treatment involved multiple stages which included a response prevention procedure, extinction, and systematic desensitization.     

Changes in orienting and habituation in the rat following administration of chlorpromazine

Chlorpromazine (0.5-3.0 mg/kg) significantly reduced orienting to a novel auditory stimulus, but subsequent habituation after repeated presentations of the stimulus was not prevented nor significantly impaired. These results support the suggestion that the mechanisms underlying orienting and habituation are independent.     

The effects of delay on neonatal retention of habituated head-turning

Recovery of neonatal head orientation following auditory habituation was used to examine the effects of intertrial delay. One of two words served as stimuli with criterion orienting and habituation established before the delay. Fifty-six full-term neonates were assigned randomly to one of four delay groups: 10 (control), 55, 100, or 145 s. The percentage of head-turns toward the sound source (with one turn per trial) for blocks of three trials served as the principal dependent variable. Recovery of localized head-turning increased as length of delay increased, with the 100- and 145-s groups showing greater recovery than the 10- and 55-s groups. Infants presented with control trials systematically turned away from the sound source following habituation. Selective sensory adaptation, spontaneous recovery, and short-term memory interpretations of these data are considered.     

Sex and menstrual cycle differences in the habituation and spontaneous recovery of the electrodermal orienting reaction

Sex and menstrual cycle differences have been widely observed in electrodermal activity. The aim of this study was to investigate these differences in the electrodermal orienting reaction employing a habituation-spontaneous recovery procedure. According to previous research it was predicted that men and preovulatory women should show higher electrodermal responses, higher skin conductance levels, and slower habituation rates. Thirty-two subjects (16 males and 16 females) were presented with two series of tones, 10 in the first series and eight in the second, with a 4-min rest period between the two series. Half of the subjects received the same 5-sec tone (80 dB, 1000 Hz) in each presentation while the other half received 80-dB, 5-sec tones which varied randomly in frequency (100, 500, 1000 Hz). Women were divided into two groups; preovulatory (n = 7) and postovulatory (n = 8) according to their answers to a retrospective questionnaire. The mean response amplitude was higher in the group of males, who habituated later than females. Postovulatory women showed lower orienting reactions in the first series, and habituated faster than did preovulatory women in the two series. There were neither significant differences between males and females, nor between preovulatory and postovulatory women in tonic conductance levels. These results support the existence of greater electrodermal reactivity in males and in preovulatory women.     

Cardiac orienting responses of 6- and 16-week-old infants

Since previous data suggested that the magnitude of orienting evidenced by cardiac deceleration increased over the first 16 weeks of life, 6- and 16-week-old infants were compared on various characteristics of orienting: habituation, dishabituation, and magnitude of deceleration to stimulus offset as well as to stimulus onset. Neither the change in stimulus following habituation trials nor the stimulus offset produced a large enough response to confidently evaluate age differences suggested by the data. Stimulus onset elicited a pronounced deceleration which for the two age groups was of equivalent magnitude on initial trials and declined similarly with stimulus repetition. It was suggested that similarity of the two age groups on these parameters was due to control of state within a narrow alert range, and that, in general, younger infants are less likely than older infants to show orienting when conditions for orienting are marginal.     

Heart-rate and electrodermal orienting responses to visual stimuli differing in complexity

Orienting response (OR) theory predicts that amount of information in the stimulus, or stimulus complexity, should be an important determinant of OR elicitation and habituation, more intense and more slowly habituating ORs being expected to complex than to simple stimuli. This prediction was tested in an experiment where subjects were exposed to simple and complex visual stimuli in randomized order, while heart-rate and skin conductance were measured. Complex stimuli evoked a more pronounced deceleratory heartrate response than did simple stimuli. However, the two conditions did not differ in rate of habituation of this response. For skin conductance responses, on the other hand, the complex stimulus took more trials than the simple stimulus to reach habituation, whereas the two conditions did not differ in response magnitude. Thus, the hypothesis of more intense orienting to complex stimuli was supported by the heart-rate data, and that of slower habituation to complex stimuli, of the skin conductance data.     

Contextual control of long-term habituation in rats

This study examined contextual control of long-term habituation and whether such effects are dependent on the habituating response system. Habituation of the acoustic startle response transferred from the home cage to the testing context, whereas habituation of lick suppression was context specific (Experiments 1 and 2). Contextual control of habituation was demonstrated between 2 experimental contexts for lick suppression to a tone (Experiment 3) and bar-press suppression to a light (Experiment 4). Experiment 5 extinguished habituation of lick suppression and the orienting response to a tone with 27 exposures to the habituation context. Context specificity of both responses also was found. Previous failures to demonstrate contextual control of habituation may be due to the choice of response system and to less sensitive procedures to detect response recovery. The habituation mechanism for startle is independent from the process or processes that underlie habituation in other response systems, but the nature of these mechanisms is not yet known.     

Aging, selective attention, and inhibitory processes: a psychophysiological approach.

The present study investigated the efficiency with which younger and older adults allocate attention to relevant and irrelevant stimuli. The model of attention guiding this research links the orienting response with the allocation of attention and habituation with the inhibition of the allocation of attention. We adapted a paradigm developed by Iacono and Lykken (1983) in which subjects are instructed unambiguously either to attend to or to ignore a series of innocuous tones, and the skin conductance orienting response elicited by each tone is measured. Results revealed that young subjects instructed to ignore the tones habituated more quickly than did those instructed to attend to the tones. However, older adults exhibited nondifferential orienting across the 2 instruction conditions. These results suggest an age-related deficit in the ability to inhibit attention to irrelevant stimuli.     

Twenty-four hours of total sleep deprivation selectively impairs attentional networks

Performance decrements after sleep loss have been extensively studied and are usually attributed to generic attentional deficits. This claim, however, is based on the view of attention as a unitary construct, despite evidence that it should be considered a multidimensional cognitive ability. The aim of the present study was to evaluate the impact of one night of sleep deprivation on the efficiency of three attentional networks, defined by Posner and Raichle (1994) in anatomical and functional terms, as alerting, orienting, and executive control. Thirty participants performed the Attention Network Test at 9:00 a.m. following two different sleep conditions: baseline (a normal night of sleep) and deprivation (24 hrs of wakefulness). Results showed an overall slowing in reaction times and a significant decrease in accuracy after sleep deprivation. Sleep deprivation selectively affected the three attentional networks, given that only executive control efficacy significantly decreased after sleep deprivation. By contrast, phasic alerting and orienting showed no differences in the two sleep conditions. Thus, performance deficits following sleep deprivation do not reflect global attentional deficits.     

Change in the event-related skin conductivity: an indicator of the immediate importance of elaborate information processing?]

In recent psychophysiological conceptualizations of the orienting response (OR) within the framework of information processing, the OR is increasingly considered a "call for processing resources", something which is especially inferred from variations in the event-related skin conductance response (SCR). The present study, therefore, was concerned with certain implications arising from this framework or perspective, particularly in regard to the question of whether stimuli eliciting skin conductance responses obligatorily receive/evoke processing priority or not. In order to examine whether these electrodermal responses denote a capturing of attention or merely a call for processing resources, short (1 s) pure sine tones of 65 dB with sudden onset (commonly used as orienting stimuli) were inserted in a reaction time paradigm with an additional memory load. This demand was primarily given because memory processes play a key role in theories of orienting and habituation. The task was run under two different conditions of complexity, factorially combined with a novelty variation of the added auditory stimuli. The results revealed a substantial deterioration of task performance subsequent to the occurrence of the tones, which, however, was dependent on task complexity and on novelty of the tones. The task impairment is particularly remarkable as subjects were asked to avoid distractions by paying attention to the task and as the tones were introduced as subsidiary and task-irrelevant. Together with the missing effects of task complexity on phasic and tonic electrodermal activity, results suggest that information-processing conceptualizations of the OR can only be a meaningful heuristic contribution to theoretical developments about human orienting and its habituation if the setting of processing priority, its conditions, as well as its implications are adequately taken into account. In addition, it seems to be promising to consider the strength of the SCR as an index of urgency of elaborate, attention-demanding processing and not as a peripheral physiological manifestation of the OR, or, respectively, of a call for unspecific processing resources. Such a view would also do justice to the aspect of prioritization. The sufficient conditions for an OR's occurrence could, in this context, be equated with, among others, some of those which activate a mechanism subserving selective attention and, as a possible result, which lead to further and more elaborate processing of potentially important information.     

Automatic attentional orienting to other people’s gaze in schizophrenia

Explicit tests of social cognition have revealed pervasive deficits in schizophrenia. Less is known of automatic social cognition in schizophrenia. We used a spatial orienting task to investigate automatic shifts of attention cued by another person’s eye gaze in 29 patients and 28 controls. Central photographic images of a face with eyes shifted left or right, or looking straight ahead, preceded targets that appeared left or right of the cue. To examine automatic effects, cue direction was non-predictive of target location. Cue–target intervals were 100, 300, and 800?ms. In non-social control trials, arrows replaced eye-gaze cues. Both groups showed automatic attentional orienting indexed by faster reaction times (RTs) when arrows were congruent with target location across all cue–target intervals. Similar congruency effects were seen for eye-shift cues at 300 and 800?ms intervals, but patients showed significantly larger congruency effects at 800?ms, which were driven by delayed responses to incongruent target locations. At short 100-ms cue–target intervals, neither group showed faster RTs for congruent than for incongruent eye-shift cues, but patients were significantly slower to detect targets after direct-gaze cues. These findings conflict with previous studies using schematic line drawings of eye-shifts that have found automatic attentional orienting to be reduced in schizophrenia. Instead, our data indicate that patients display abnormalities in responding to gaze direction at various stages of gaze processing—reflected by a stronger preferential capture of attention by another person’s direct eye contact at initial stages of gaze processing and difficulties disengaging from a gazed-at location once shared attention is established.