Type of physical exercise and inhibitory function in older adults: An event-related potential study

ObjectivesThe present study was to examine the relationship between exercise type and inhibitory function in older adults using neuroelectric indices.DesignA cross-sectional design was employed in the present study.MethodSixty adults (M = 69.42 years) were categorized into open-skill, closed-skill, and irregular exercise groups according to their history of exercise participation. The participants conducted a flanker task while their behavioral performance and event-related brain potentials were assessed.ResultsThe results indicated that regular exercisers, regardless of exercise type, exhibited a faster reaction time across conditions of the flanker task compared to irregular exercisers. For the P300 amplitude of the open-skill exerciser group, the peak amplitude was larger at the vertex site compared to the frontal site, whereas no site differences were observed in the closed-skill and irregular exerciser groups.ConclusionsThese findings extend current knowledge by suggesting that, for older adults, participation in physical exercise involving increased cognitive demand is associated with better neural efficiency in resource allocation for tasks that require interference control.     

Similar improvements in inhibitory control following low-volume high-intensity interval exercise and moderate-intensity continuous exercise

ObjectivesWe previously demonstrated that a traditional high-volume (HV) high-intensity interval exercise (HIIE) was more effective in improving post-exercise inhibitory control (IC) than moderate-intensity continuous exercise (MCE). Nevertheless, because HV-HIIE is performed with a higher volume and longer duration, it may result in decreased adherence to this exercise for some individuals. In this study, we compared the effect of a practical low-volume (LV) HIIE to that of MCE on post-exercise IC improvements.DesignTwenty healthy males performed both LV-HIIE and MCE on a cycle ergometer in a crossover design.MethodLV-HIIE was consisted of ten 1-min bouts at 90% of the peak oxygen consumption (VO_{2 peak}) with 1-min active recovery at 30% of VO_{2 peak}, which had a total duration of 20 min. MCE was performed for 40 min at 60% of VO_{2 peak}. To evaluate IC, the Stroop test was administered before exercise, immediately after exercise, and every 10 min during the 30-min post-exercise recovery period.ResultsIC significantly improved immediately after LV-HIIE and MCE compared with that before each exercise (both Ps < 0.05). The improved IC remained significant until the 20-min post-exercise recovery period for both protocols (all Ps < 0.05). The degrees of post-exercise IC improvements throughout the 30-min post-exercise recovery period did not differ significantly between protocols.ConclusionsThese findings demonstrated that despite lower exercise volume and shorter exercise duration, LV-HIIE could improve post-exercise IC similar to MCE.     

The relationship between physical fitness and inhibitory ability in children with attention deficit hyperactivity disorder: An event-related potential study

ObjectivesThe purpose of the current study was to examine the relationship between physical fitness and interference control by comparing higher and lower fitness children with attention deficit hyperactivity disorder (ADHD) using event-related potentials (ERPs) and behavioral indices.DesignCross-sectional design was employed.MethodEighty children, previously diagnosed with ADHD, were evaluated on their inhibitory ability as measured during their participation in the flanker task, and this ability was examined in relationship to measures of their physical fitness. Only children in the top 40% or in the bottom 40% of the distribution for each fitness components were included in the statistical analysis.ResultsThe results showed that children with higher levels of muscular endurance, muscular power, and aerobic capacity had shorter reaction times (RT) and larger P3 amplitudes compared to less fit children. In addition, children with lower body composition had shorter reaction times and shorter P3 latencies compared to those with higher body composition.ConclusionsBetter physical fitness, especially muscular endurance, muscular power, aerobic capacity, and body composition, were associated with enhanced interference control in children with ADHD. Our findings suggest the need for a closer examination of the possible impact of different aspects of fitness on the general relationship between physical fitness and cognition.     

Reduced emotional stress reactivity to a real-life academic examination stressor in students participating in a 20-week aerobic exercise training: A randomised controlled trial using Ambulatory Assessment

ObjectivesTo examine if a preventive 20-week aerobic exercise intervention (AET) can improve emotional stress reactivity during real-life stress.DesignRandomised controlled trial; within-subject design.MethodSixty-one inactive students were randomly assigned to a waiting control and an AET group. To capture the situation-specific, intra-individual data in real life, electronic diaries were used. Participants reported their moods and perceived stress (PS) repeatedly over two days during their daily routines pre- and post-intervention. The pre-intervention baseline assessment was scheduled at the beginning of the semester, and the post-intervention assessment was scheduled at a real-life stressful episode, an academic examination. For the aerobic fitness assessment, both groups completed a cardiopulmonary exercise test on the treadmill before and after the intervention. Multilevel models (MLMs) were conducted to compare within- and between-subject associations.ResultsSignificant emotional stress reactivity was evident in both groups during all assessment periods. However, participants in the AET group showed lower emotional stress reactivity compared with their control counterparts after the 20-week training programme during the real-life stress episode (the academic examination).ConclusionsAET conferred beneficial effects on emotional stress reactivity during an academic examination, which is likely an extremely stressful real-life situation for students.AET appears to be a promising strategy against the negative health effects of accumulated emotional stress reactivity.     

The effects of aerobic exercise on working memory in methamphetamine-dependent patients: Evidence from combined fNIRS and ERP

ObjectiveTo explore the effect of aerobic exercise on working memory according to exercise intensity in patients with methamphetamine (MA) dependence.DesignTwelve-week randomized controlled trial.MethodForty-five MA-dependent patients were divided randomly into three groups participating in 12-week moderate- and high-intensity aerobic exercise interventions and no intervention (control), respectively. Working memory performance was assessed using a 2-back task, and a combined functional near-infrared spectral imaging–event-related potential measure was used to identify spatial and temporal components of the neurofunctional underpinnings of this performance.ResultsHigh-intensity exercise significantly enhanced the discernment aspect of working memory. It also decreased N1 and P2 amplitudes, and increased neural activity in the left dorsolateral prefrontal cortex.ConclusionsThe findings of this study suggest that high-intensity aerobic exercise can enhance working memory and neural activity in MA-dependent patients, and thus that it may serve as an effective therapeutic tool for these patients.     

Rhythmic Auditory Music Stimulation increases task-distraction during exercise among cardiac rehabilitation patients: A secondary analysis of a randomized controlled trial

ObjectiveThe aim of this study was to determine the mechanisms by which Rhythmic Auditory Music Stimulation (RAMS) improves exercise among patients participating in cardiac rehabilitation.Methods168 English speaking patients over the age of 18 years, were recruited from the Cardiac Rehabilitation and Prevention Program. Participants were randomly assigned to one of three groups (n = 56 each) as part of a 12-week intervention: (1) RAMS (2) preference-based audiobooks, or (3) white noise or silence audio-controls. All participants received an iPod with the audio intervention to maintain blinding. Study outcomes included pace-deviation between actual vs. prescribed exercise, self-reported arousal, perceived exertion, task-attentiveness during exercise and perceptual experiences associated with the audio-content itself.Trial registryClinicaltrials. gov NCT02946060.ResultsAn individual's actual exercise pace was highly correlated with their prescribed exercise pace, with no significant differences in pace deviation across interventions (P = 0.61). Patients randomized to RAMS or audiobooks reported significantly lower arousal scores during exercise (P = 0.01), lower exercise-attentiveness (P < 0.001), and modestly lower perceived exertion (P = 0.06) during exercise than did controls. Participants assigned to RAMS and audiobooks reported being more attentive to, and happy with, their overall audio-experiences during exercise than controls (P < 0.001).ConclusionsRAMS playlists and audiobooks induced a mood-enhancing task-distraction effect during exercise. Such findings may underscore the potential benefits of preference-based audio-content during exercise.     

Neuropsychological and neurophysiological effects of strengthening exercise for early dementia: A pilot study

ABSTRACT

Research demonstrates a positive effect of aerobic exercise on cognitive functioning in older adults. Unfortunately, aerobic exercise is often contraindicated for older adults due to cardiovascular and functional limitations. Low-intensity strengthening exercise may offer a practical alternative, but the neuropsychological benefits and potential neurophysiological mechanisms are less well understood. The current study evaluated the effects of a 10-week strengthening exercise intervention on cognitive functioning and EEG in a sample of 13 older adults with early dementia, and 9 normative controls. Results revealed beneficial effects of strengthening exercise on verbal memory coupled with frontal beta and delta power asymmetries and N200 amplitude asymmetry. Results point to increased cognitive efficiency following 10 weeks of strengthening exercise. The findings suggest it is feasible to conduct a strengthening intervention with early dementia patients, and to gather neuropsychological and neurophysiological data to evaluate outcomes. Strengthening exercise may serve as a useful alternative to aerobic exercise.     

Real-time kinematic biofeedback improves scapulothoracic control and performance during scapular-focused exercises: A single-blind randomized controlled laboratory study

Emerging evidence suggests that scapular-focused therapeutic exercises hold promise for shoulder dynamic stability retraining. While recent findings show that therapeutic exercises can alter scapular neuromuscular function measured with muscle electromyography, no study has yet addressed the effects of kinematic biofeedback for improving scapulothoracic control and performance. The aim of this study was to assess the effectiveness of kinematic biofeedback on motor relearning transfer during shoulder flexion and a daily activity, on the quality of scapular-focused exercise performance, and on execution time. Thirty healthy young adults were randomly distributed into two groups. Skin mounted electromagnetic sensors were used to collect kinematic data of the thorax, scapula and humerus while subjects performed a shoulder flexion and a daily activity, prior to and after scapular-focused exercises. For both groups, the exercise execution error and the execution time determined the scapulothoracic control and performance. Significant statistical differences were found in the exercise execution error results within the experimental group (z = 5.313; p = 0.037) and between groups (u = 37.00; p = 0.001; u = 64.00; p = 0.024). This study’s results demonstrate that real-time kinematic biofeedback improves scapulothoracic control and performance during scapular-focused exercise execution.     

Individual differences in executive functioning and theory of mind: An investigation of inhibitory control and planning ability

This research examined the relative contributions of two aspects of executive function-inhibitory control and planning ability-to theory of mind in 49 3- and 4-year-olds. Children were given two standard theory of mind measures (Appearance-Reality and False Belief), three inhibitory control tasks (Bear/Dragon, Whisper, and Gift Delay), three planning tasks (Tower of Hanoi, Truck Loading, and Kitten Delivery), and a receptive vocabulary test (Peabody Picture Vocabulary Test [PPVT-3]). Multiple regression analyses indicated that two inhibition tasks (Bear/Dragon and Whisper) were significantly related to theory of mind after accounting for age, receptive vocabulary, and planning. In contrast, the planning tasks did not share unique variance with theory of mind. These results increase our understanding of the specific nature of executive function-theory of mind relations during early childhood.     

The effectiveness of a school mindfulness-based intervention on the neural correlates of inhibitory control in children at risk: A randomized control trial

Interest in the applications of mindfulness practice in education is growing in the scientific community. Recent research has shown that mindfulness practice in schools may be beneficial for executive functions (EFs) which are abilities crucial for healthy development. The study of the effects of mindfulness practices on children's neural correlates of EFs, particularly inhibitory control, may provide relevant information about the impact and mechanisms of mindfulness-based interventions (MBIs) in children. The aim of the present study was to investigate the effects of a MBI in elementary school children on the neural correlates of inhibitory control via a randomized controlled trial. Children from two 4th grade classrooms and two 5th grade classrooms located in a school identified as having low socioeconomic status in Santiago de Chile were randomly assigned to either receive a MBI or serve as active controls and receive a social skills program. Both before and after the interventions, electroencephalographic activity was recorded during a modified version of the Go/Nogo task in a subsample of children in each group. Additionally, teachers completed questionnaires of students’ EFs and students completed self-report measures. Results revealed increases in EFs assessed by questionnaires together with improved P3 amplitude associated with successful response inhibition in children who received the MBI compared to active controls. These results contribute to the understanding of the ways in which mindfulness practices can promote the development of inhibitory control together with EF improvement, factors identified as critical for children's social and emotional development and positive mental health.

Research Highlights

• This study investigated the effects of a mindfulness-based intervention in children from a low socioeconomic status school on neural correlates of EFs.
• Children performed a Go/Nogo task while electroencephalographic activity was recorded and completed questionnaires before and after a MBI or an active control program.
• Improvements in EFs assessed by questionnaires together with an increased Nogo-P3 activity associated with successful inhibition in children who received the MBI were found.
• The results could contribute to understand how mindfulness practice can promote the development of inhibitory control in children from vulnerable populations.

     

A randomized controlled trial of Internet-based self-help training for recurrent headache in childhood and adolescence

Two different self-help training programs (multimodal cognitive-behavioral training (CBT) and applied relaxation (AR)) presented via the Internet were compared with an educational intervention (EDU) in an RCT. Sixty-five children and adolescents (mean age: 12.7 years) with recurrent headache (at least 2 attacks per month) were each assigned to one of the three treatment conditions. The main outcome variables related to changes in headache frequency, intensity and duration as well as the responder rate (50% reduction of headache frequency) and NNTs. Secondary outcome variables were pain catastrophizing and general well-being (depression, psychopathological symptoms and health-related quality of life). All groups showed significant reduction in headache frequency, duration and pain catastrophizing, but not in headache intensity, depression, psychopathological symptoms or health-related quality of life at post-assessment. NNTs were 2.0 for the comparison CBT and EDU; 5.2 for the comparison of AR and EDU at post-treatment. The highest responder rates at post were from CBT (63%), significantly different compared to AR (32%) and EDU (19%), whereas at follow-up no significant differences were found (CBT: 63%, AR: 56%, EDU: 55%) reflecting in the NNTs.The effects remain stable in headache frequency, pain catastrophizing and psychopathological symptoms across all groups at follow-up assessment. CBT showed the highest within-effect size in headache frequency, duration and pain catastrophizing. The results support the use of Internet programs for pediatric recurrent headache, especially given their accessibility and suitability for children and adolescents. Further studies are needed to improve their quality and efficacy.     

Effects of an acute bout of localized resistance exercise on cognitive performance in middle-aged adults: A randomized controlled trial study

ObjectivesTo examine the effect of an acute bout of resistance exercise on cognitive performance in healthy middle-aged adults.DesignA randomized controlled trial design.MethodsForty-one adults (M_age = 49.10 years, SD = 8.73) were randomly assigned to either resistance exercise or a control condition. The resistance exercise condition consisted of 2 sets of 10 repetitions for 6 exercises, and the control condition involved reading about resistance exercise for a time period approximating the duration of the exercise condition. The Stroop Test and the Trail Making Test (TMT) were completed at baseline and immediately following performance of the treatment.ResultsResults indicated that resistance exercise significantly benefits speed of processing (Stroop Word and Stroop Color), and that there is a trend towards resistance exercise benefiting performance on an executive function task (Stroop Color–Word) that requires shifting of the habitual response. However, the results for the TMT were not significant which demonstrates that acute resistance exercise has a limited effect on inhibition.ConclusionThe present findings extend the literature by indicating that an acute bout of resistance exercise has a positive impact on automatic cognitive processes and on particular types of executive function in middle-aged adults.     

The potential mediating role of anxiety sensitivity in the impact of mindfulness training on anxiety and depression severity and impairment: A randomized controlled trial

The benefits of mindfulness-based interventions to alleviate anxiety and depression have been supported by many studies. Given the effectiveness of mindfulness-based interventions on anxiety and depression, the underlying mechanisms need to be explored. Using a randomized waitlist-controlled design, this study investigated whether anxiety sensitivity was a potential mechanism for the impact of mindfulness training on anxiety and depression. Participants with high psychological distress were randomly assigned to an eight-week mindfulness intervention (N = 35) or a wait-list control group (N = 34). Before and after the intervention or corresponding waitlist period, participants completed measures of anxiety and depression severity and impairment and anxiety sensitivity. Separate mixed ANOVA demonstrated significant group (intervention vs. control group) × time (pre- vs. post-test) interactions for anxiety sensitivity and overall anxiety severity and impairment and marginally significant interaction for overall depression severity and impairment. Moreover, simple mediation models showed that reductions of anxiety sensitivity from pre- to post-test mediated the impact of mindfulness training on changes in anxiety and depression severity and impairment. The findings suggest that anxiety sensitivity is a potential mechanism underlying the effect of mindfulness training on anxiety and depression, which provides a new perspective for the study of processes of change of mindfulness-based interventions.     

The effects of mindfulness training on beginners' skill acquisition in dart throwing: A randomized controlled trial

ObjectivesThe present study was into whether or not mindfulness training, based on the mindfulness-acceptance-commitment approach (MAC), can improve beginners' skill acquisition of dart throwing.DesignRandomised controlled trial.MethodsA total of 43 first-year college students who had not played darts professionally prior to the study were randomly assigned to either an attention control group (n = 21) or a mindfulness training group (n = 22) during an eight-week dart training program. Dart throwing and psychological variables were assessed at pre-intervention, post-intervention, and two-week follow-up.ResultsTwo-way repeated measures ANOVA revealed that the mindfulness group, but not the attention control group had significant improvements in mindfulness, experiential acceptance, and flow at post-intervention and follow-up. Although both groups improved dart throwing performance after the intervention, the improvement of the mindfulness group was statistically higher in comparison to that of the attention control group.ConclusionsIt was concluded that the MAC approach could improve the performance and adaptive sport experience of beginners in dart throwing.     

Space Fortress game training and executive control in older adults: A pilot intervention

ABSTRACT

We investigated the feasibility of using the Space Fortress (SF) game, a complex video game originally developed to study complex skill acquisition in young adults, to improve executive control processes in cognitively healthy older adults. The study protocol consisted of 36 one-hour game play sessions over 3 months with cognitive evaluations before and after, and a follow-up evaluation at 6 months. Sixty participants were randomized to one of three conditions: Emphasis Change (EC) – elders were instructed to concentrate on playing the entire game but place particular emphasis on a specific aspect of game play in each particular game; Active Control (AC) – game play with standard instructions; Passive Control (PC) – evaluation sessions without game play. Primary outcome measures were obtained from five tasks, presumably tapping executive control processes. A total of 54 older adults completed the study protocol. One measure of executive control, WAIS-III letter–number sequencing, showed improvement in performance from pre- to post-evaluations in the EC condition, but not in the other two conditions. These initial findings are modest but encouraging. Future SF interventions need to carefully consider increasing the duration and or the intensity of the intervention by providing at-home game training, reducing the motor demands of the game, and selecting appropriate outcome measures.     

Combined cognitive and parent training interventions for adolescents with ADHD and their mothers: A randomized controlled trial

This study examined the individual and combined effects of two nonpharmacological treatments for attention deficit/hyperactivity disorder (ADHD): Cogmed working memory training (CWMT) for adolescents and behavioral parent training (BPT) for mothers. Ninety-one adolescents (ages 11–15) and their mothers were randomized to one of four CWMT and BPT treatment and active control (placebo) group combinations of 5-week interventions. At pre- and posttest, mothers and teachers completed rating forms, and adolescents completed neuropsychological measures of working memory (WM). Individual intervention effects showed that treatment CWMT significantly improved WM spans, whereas there were no significant differences for treatment or control BPT on reports of parent-related outcomes. Combined treatment effects indicated an overall pattern of greatest improvements for the control CWMT/treatment BPT group, as compared to the other three groups, on adolescent WM deficit, behavioral regulation problems, and global executive deficit. Most significant effects for outcomes were main effects of improvements over time. A combination of CWMT and BPT did not result in increased treatment gains. However, potential effects of combined treatment may have been masked by greater perceived benefits arising from lack of struggle in the nonadaptive, CWMT active control condition. Future combined intervention research should focus on specific, theoretically driven WM deficits among individuals with ADHD, should include possible adaptations to the standard CWMT program, should examine effectiveness of cognitive treatments combined with contextual interventions and should utilize appropriate control groups to fully understand the unique and combined effects of interventions.     

Latent structure of executive function in five- and six-year-old children: A longitudinal study

This longitudinal study analyses the structure of executive function in children assessed at five and six years of age and examines the longitudinal relationships between the executive function dimensions identified at the two age levels. Confirmatory factor analysis was used to examine the latent structure of executive function at both age levels. The best fit to the data at both age levels was a two-factor model in which inhibition was distinguished, while working memory and shifting emerged as a unitary component. Some variables show a moderate longitudinal stability and the inhibitory control tasks display reduced continuity across ages.     

Interactive effects of dispositional mindfulness and PETTLEP imagery training on basketball shooting performance: A randomized controlled trial

The purpose of this study was to examine the interactive effects of dispositional mindfulness and visualized PETTLEP imagery training on basketball mid-range shooting performance and retention. Seventy-three participants (M age = 20.32 ± 1.09) with high/low dispositional mindfulness (high n = 35; low n = 38) selected out of 302 college students were randomly assigned into the following six groups: (a) high mindfulness internal imagery (H-II, n = 13); (b) high mindfulness external imagery (H-EI, n = 11); (c) high mindfulness control (H–CO, n = 11); (d) low mindfulness internal imagery (L-II, n = 13); (e) low mindfulness external imagery (L-EI, n = 12); and (f) low mindfulness control (L-CO, n = 13). Participants engaged in a pretest to measure their basketball shooting performance, then participated in a 6-week (3 times/per-week) intervention, plus a posttest and retention test. A three-way 2 (high/low mindfulness) X 3 (treatments: internal-, external imagery, and control) X 3 (measurement time: pretest, posttest, and retention) mixed ANOVA statistical analysis found dispositional mindfulness interacted with treatments and measurement time. The main effects showed high dispositional mindfulness performed better than low dispositional mindfulness, and internal imagery training performed better than external imagery training on mid-range basketball performance at retention. The 3–way interaction indicated that when using either internal or external imagery, high dispositional mindfulness performed better than low mindfulness on retention but not posttest. For 2-way interaction, high dispositional mindfulness performed better than low dispositional mindfulness on retention but not posttest. Our results extended current knowledge on sport imagery and dispositional mindfulness and gained several theoretical implications for researchers. The limitations, future research directions, and practical implications were also discussed.     

Component analysis of verbal versus spatial working memory training in adolescents with ADHD: A randomized,controlled trial

Adaptive training of working memory (WM) using the Cogmed-RM intervention has recently shown some efficacy as an alternative treatment for ADHD, but this intervention may not be optimally designed. A recent component analysis of WM has suggested that maintenance in primary memory (PM) appears to be largely intact whereas recall from secondary memory (SM) appears to be deficient in ADHD relative to age-matched controls. However, extrapolating from basic research, there is reason to believe that Cogmed-RM may target the PM component more than the SM component; though training with spatial exercises may target the SM component more than training with verbal exercises. To investigate, participants diagnosed with ADHD were randomly assigned to either a verbal training condition (n?=?24) or a spatial training condition (n?=?23) using a randomized, controlled design, and both groups were instructed to complete at least 20 days of training. The PM and SM components of WM were assessed immediately before and after training using both verbal and spatial free recall tasks. The main findings showed that both versions of the intervention enhanced the maintenance of information in PM regardless of test modality, but not the recall of information from SM. Therefore, the component of WM that is improved by Cogmed-RM is not the same component of WM that is deficient in ADHD.     

The academic outcomes of working memory and metacognitive strategy training in children: A double‐blind randomized controlled trial

Working memory training has been shown to improve performance on untrained working memory tasks in typically developing children, at least when compared to non‐adaptive training; however, there is little evidence that it improves academic outcomes. The lack of transfer to academic outcomes may be because children are only learning skills and strategies in a very narrow context, which they are unable to apply to other tasks. Metacognitive strategy interventions, which promote metacognitive awareness and teach children general strategies that can be used on a variety of tasks, may be a crucial missing link in this regard. In this double‐blind randomized controlled trial, 95 typically developing children aged 9–14 years were allocated to three cognitive training programmes that were conducted daily after‐school. One group received Cogmed working memory training, another group received concurrent Cogmed and metacognitive strategy training, and the control group received adaptive visual search training, which better controls for expectancy and motivation than non‐adaptive training. Children were assessed on four working memory tasks, reading comprehension, and mathematical reasoning before, immediately after, and 3 months after training. Working memory training improved working memory and mathematical reasoning relative to the control group. The improvements in working memory were maintained 3 months later, and these were significantly greater for the group that received metacognitive strategy training, compared to working memory training alone. Working memory training is a potentially effective educational intervention when provided in addition to school; however, future research will need to investigate ways to maintain academic improvements long term and to optimize metacognitive strategy training to promote far‐transfer. A video abstract of this article can be viewed at https://youtu.be/-7MML48ZFgw