Type of physical exercise and inhibitory function in older adults: An event-related potential study

ObjectivesThe present study was to examine the relationship between exercise type and inhibitory function in older adults using neuroelectric indices.DesignA cross-sectional design was employed in the present study.MethodSixty adults (M = 69.42 years) were categorized into open-skill, closed-skill, and irregular exercise groups according to their history of exercise participation. The participants conducted a flanker task while their behavioral performance and event-related brain potentials were assessed.ResultsThe results indicated that regular exercisers, regardless of exercise type, exhibited a faster reaction time across conditions of the flanker task compared to irregular exercisers. For the P300 amplitude of the open-skill exerciser group, the peak amplitude was larger at the vertex site compared to the frontal site, whereas no site differences were observed in the closed-skill and irregular exerciser groups.ConclusionsThese findings extend current knowledge by suggesting that, for older adults, participation in physical exercise involving increased cognitive demand is associated with better neural efficiency in resource allocation for tasks that require interference control.     

Executive and attentional contributions to Theory of Mind deficit in attention deficit/hyperactivity disorder (ADHD)

Attention deficit/hyperactivity disorder (ADHD) in children has been associated with attentional and executive problems, but also with socioemotional difficulties possibly associated with deficits in Theory of Mind (ToM). Socioemotional problems in ADHD are associated with more negative prognoses, notably interpersonal, educational problems, and an increased risk of developing other psychiatric disorders that emphasize the need to clarify the nature of their ToM deficits. In this study, we hypothesized that ToM dysfunction in children with ADHD is largely attributable to their attentional and/or executive deficits. Thirty-one children with ADHD (8–12 years, IQ > 85) and 31 typically developing (TD) children were assessed using executive functions (inhibition, planning, and flexibility) and attentional tasks, as well as two advanced ToM tasks (Reading the Mind in the Eyes and Faux Pas) involving different levels of executive control. Children with ADHD performed more poorly than TD children in attentional, executive function, and ToM tasks. Linear regression analyses conducted in the ADHD group indicated that inhibition scores predicted performance on the “Faux Pas” task the best, while attention scores were the best for predicting performance on the Reading the Mind in the Eyes task. When controlled for inhibition and attentional variables, ToM performance in children with ADHD was actually similar to TD children. Contrarily, controlling for ToM scores did not normalize performance for inhibition and attentional tasks in children with ADHD. This unidirectional relationship suggests that deficits in the EF and attentional domains are responsible for ToM deficits in ADHD, which therefore may contribute to their socioemotional difficulties.     

Prepotent response inhibition predicts treatment outcome in attention deficit/hyperactivity disorder

Objective: Inhibition deficits, including deficits in prepotent response inhibition and interference control, are core deficits in ADHD. The predictive value of prepotent response inhibition and interference control was assessed for outcome in a 10-week treatment trial with methylphenidate. Methods: Thirty-four children with ADHD (ages 8–12) received 10 weeks of methylphenidate treatment. At pretest prepotent response inhibition was assessed using the Stop-Signal Task; interference control was assessed using the Stroop Color-Word task. Methylphenidate was individually titrated to an optimal dose. Treatment outcome was assessed by parent- and teacher-rated ADHD behavior. Results: Only stop-signal reaction time of the Stop-Signal Task was a significant predictor of parent-rated levels of inattention and hyperactivity/impulsivity at outcome. Children with lower levels of inhibition showed worse outcome after 10 weeks of treatment, independent of medication dose. Conclusions: Low levels of prepotent response inhibition are associated with worse response to treatment with methylphenidate. Prepotent response inhibition may be an intermediate phenotypical predictor of treatment outcome.     

Effects of a single bout of moderate-to-vigorous physical activity on executive functions in children with attention-deficit/hyperactivity disorder: A systematic review and meta-analysis

ObjectivesThe aim of this study was to systematically review the literature investigating the acute effects of moderate-to-vigorous physical activity (MVPA) on executive functions (EFs) in children with attention-deficit/hyperactivity disorder (ADHD) and perform a meta-analysis of the effects of MVPA on task components that require lower and higher EF demand in this population.MethodsThe systematic review and meta-analysis followed the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines. Six electronic databases, i.e., PubMed, Scopus, Web of Science, Embase, SPORTDiscus, and Education Resources Information Center (ERIC), were searched for eligible studies. Random-effects weights were used to pool the effect sizes. Publication bias was assessed by Egger’s regression test and Rosenthal’s fail-safe N. This study is registered on PROSPERO, number CRD42020184082.ResultsThe electronic database search yielded 12 studies, which met the inclusion criteria, comprising a total of 375 participants. Eleven studies with data from 275 participants were included in the meta-analysis to examine the acute effects of MVPA on tasks with lower and higher EF demand. A single bout of MVPA had a small positive effect on tasks with lower (n = 10, g = 0.32, 95% CI = 0.123–0.517) and higher (n = 10, g = 0.25, 95% CI = 0.13–0.371) EF demand. No publication bias was found.ConclusionsA single bout of MVPA may have a general facilitative effect on cognition, indicating that acute MVPA may be a transient nonpharmacological adjunctive treatment for childhood ADHD.     

Perceptual asymmetries in normal children and children with attention deficit/hyperactivity disorder

Perceptual asymmetries in normal right-handed children (7-12 years of age) and children with attention deficit/hyperactivity disorder (ADHD), combined type, were investigated using various chimeric stimuli in free-viewing conditions. In the face-matching task, participants indicated which of two symmetrical face chimeras more closely resembled the original; in the chimeric faces task, participants indicated which of a pair of faces appeared happier; and in the grey scales task participants indicated which of two shaded rectangles appeared to be darker overall. Leftward biases were found for normal children with no effects of age. Contrary to expectations, normal leftward biases were also found for ADHD children in the face-matching and the chimeric faces tasks; however, a significant leftward bias was not observed in the grey scales task. The absence of anomalous perceptual bias in ADHD children on these purely perceptual tasks, suggests that anomalous perceptual asymmetries observed in other tasks (line bisection and cancellation tasks) may have been confounded by the motor response, and/or the explicit spatial components of those tasks.     

Prospective associations between physical fitness and executive function in adolescents: The UP&DOWN study

IntroductionThe objective of the present work is to investigate the prospective associations between physical fitness components (cardiorespiratory fitness, motor fitness, and muscular strength) and two domains of executive function (working memory and inhibitory control) in adolescents.MethodsA total of 422 Spanish adolescents (13.35 ± 1.54 years, at baseline) from the UP&DOWN study with assessments at baseline and at 2-year follow-up were included in the analysis. Physical fitness was assessed using the ALPHA Fitness Test Battery. Working memory was measured by the n-back task and inhibitory control by the go/no-go task. Relationships of physical fitness components with working memory and inhibitory control were examined using linear regression models, adjusted for confounders.ResultsHigher baseline levels of the three physical fitness components (cardiorespiratory fitness, motor fitness, and muscular strength) individually predicted better performance on the working memory (β_ranged, from .159 to .207; all p < .012) and inhibitory control (β_ranged, from 0.168 to 0.263; all p < .004) tasks at the 2-year follow-up. Muscular strength was the only component associated with inhibitory control independent of the other 2 physical fitness components (β = 0.266; p = .005).ConclusionsAll components of adolescents’ physical fitness at baseline were individually associated with better working memory and inhibitory control at 2-year follow-up. Specifically, our results revealed that muscular strength was the component showing the strongest association with executive function, and even the only fitness component associated with inhibitory control independent of the other fitness components. These findings may have important public health and educational implication, since promoting exercise programs that improve physical fitness, and particularly, muscular strength, may positively influence cognitive health.     

Use of peer-mediated intervention in children with attention deficit hyperactivity disorder

The present experiment extended and replicated the use of functional analysis and a peer-mediated intervention to decrease disruptive behavior displayed by children diagnosed with attention deficit hyperactivity disorder in an afterschool program. After determining that the participants displayed off-task behavior maintained by peer attention via a functional analysis, peer-implemented differential reinforcement of other behavior with extinction was effective in reducing participants' off-task behaviors. The use of peers as behavior-change agents is discussed, as are avenues for future research.     

Narrative abilities in children with attention deficit hyperactivity disorder and normal peers

A story retelling task was used to assess narrative abilities in 30 boys with attention deficit hyperactivity disorder (ADHD) and 30 normally developing boys, matched on age and IQ. Each boy listened to two stories and retold them for another child. Results indicated that the two groups did not differ in their ability to comprehend and extract the main ideas from the stories, but did differ in the production of narratives. Boys with ADHD provided less information overall, and their stories were more poorly organized and less cohesive and contained more inaccuracies. As a result, their stories were often confused and hard to follow. Organization and monitoring of information are functions of executive control. Thus the observed deficits in narrative production in children with ADHD may reflect underlying deficits in executive processes.This work was supported by funds from Health and Welfare Canada (NHRDP) and Medical Research Council of Canada. Portions of this paper were presented at the annual meeting of the Society for Research in Child and Adolescent Psychopathology, Zandvoort, The Netherlands, June 1991. The authors gratefully acknowledge Michael Marriott and Patricia Fulford for their assistance with data collection and two anonymous reviewers for their insightful comments.     

Sensory-motor deficits in children with developmental coordination disorder, attention deficit hyperactivity disorder and autistic disorder

Children who have been diagnosed with any one developmental disorder are very likely to meet diagnostic criteria for some other developmental disorder. Although comorbidity has long been acknowledged in childhood disorders, little is understood about the mechanisms that are responsible for the high level of comorbidity. In a series of studies, we have investigated the link between sensory-motor deficits and developmental disorders. Poor sensory-motor integration has long been implicated as a cause of motor problems in developmental disorders such as developmental coordination disorder (DCD), and our recent research has also investigated sensory-motor deficits in children with attention deficit hyperactivity disorder (ADHD) and autistic disorder. Based on a critical examination of relevant literature and some of our recent research findings, we argue that the importance of poor sensory-motor functioning in discriminating children with different disorders has been underestimated. Poor sensory-motor coordination appears to be linked to DCD, but not ADHD. Also, sensory-motor deficits in children with DCD and autistic disorder may provide insight into some of the social difficulties found in these groups of children. This research will increase our understanding of why children with one developmental disorder typically also have problems in other areas.     

The effect of conscious control on handwriting in children with attention deficit hyperactivity disorder

Two experiments were performed regarding the effect of conscious control on handwriting fluency in healthy adults and ADHD children. First, 26 healthy students were asked to write a sentence under different conditions. The results indicate that automated handwriting movements are independent from visual feedback. Second, the writing performance of 12 children with ADHD was examined on their usual medication with methylphenidate and under placebo. In comparison to placebo, medication with methylphenidate resulted in a reduced fluency of handwriting. Automated handwriting movements could be elicited in children with ADHD on medication. The results suggest that both visual and mental control of handwriting movements affect the automation of handwriting movements. Furthermore, a simple training procedure was designed and performed in a case study of a boy with ADHD.     

Family factors associated with attention deficit hyperactivity disorder and emotional disorders in children

Few well-controlled studies have identified psychosocial profiles of families of boys with ADHD and boys with emotional disorders compared with normal controls. However, the clinical and theoretical literature pinpoints four domains in which distinctive profiles would be expected to occur. In this study, twenty-two mothers and thirteen fathers of twenty-two boys with ADHD; twenty mothers and fifteen fathers of twenty boys with a mood or anxiety disorder; and twenty-six mothers and sixteen fathers of twenty-seven normal controls were compared on: (1) stress, support and quality of life; (2) current family functioning; (3) parenting style and satisfaction in the family of origin and current family; and (4) current and past parental functioning. The two clinical groups showed higher levels of stress and lower levels of both social support and quality of life than did normal controls. Both clinical groups showed deficits in current family functioning, but contrary to expectations the ADHD and emotional disorder group did not show distinctly different profiles. Parents of ADHD children reported higher levels of authoritarian parenting styles, and parents from both clinical groups reported less parenting satisfaction than did normal controls in both their current families and their families of origin. Parents of children with ADHD and emotional disorders reported greater parenting satisfaction in their families of origin than in their current families. This discrepancy was greatest for parents of ADHD children. Parents of children with ADHD and emotional disorders reported greater psychological health problems and more childhood ADHD symptomatology than did normal controls. Parents of children with ADHD and emotional disorders have significant psychosocial difficulties in family and personal functioning. Family intervention is highly appropriate for families with children who are referred for help with both types of difficulties.     

Implicit and explicit memory performance in children with attention deficit/hyperactivity disorder

The present investigation examined implicit and explicit memory in 20 children diagnosed with attention deficit/hyperactivity disorder (AD/HD) and 20 matched controls. Consistent with previous research, children with AD/HD performed more poorly than controls on an explicit test of long‐term memory for pictures. New results were that (a) there was no deficit on an implicit memory test for equivalent material and that (b) the observed deficit in explicit memory operated over and above any effects of depression/anxiety. Another finding to emerge was that AD/HD children had greater difficulty than controls in identifying pictures of objects that were presented in an unusual form, either rotated or degraded. Overall, the pattern of results is interpreted in terms of deficient effortful/resource‐intensive processes in AD/HD but intact automatic processes.     

The interplay of actual and perceived physical fitness in children: Effects on motivation and physical activity

From a sport and exercise psychology perspective, both the actual and perceived physical fitness become important for motivation towards physical activity and persistent physical activity in children no later than middle childhood (Stodden et al., 2008). To date, the effects of actual and perceived physical fitness have been investigated from a variable-centered approach (Jekauc et al., 2017). However, within this approach, the accuracy of the perceived physical fitness remains unconsidered. As actual and perceived physical fitness levels can be divergent, especially in children due to greater egocentricity and hence less comparison processes (Harter, 2006), also the accuracy of perceived physical fitness should be considered.In total, 462 children from 3rd and, approximately nine months later, from 4th grade participated in this study (M_age = 8.79 years). Third-grade students were assessed on their actual physical fitness, perceived physical fitness, and physical activity. In fourth grade, students were asked to fill out questionnaires that assess motivational regulations and physical activity. Polynomial regressions with response surface analyses were conducted to analyze main effects and accuracy effects of actual and perceived physical fitness on motivation and physical activity. Analyses revealed that children with higher actual and perceived physical fitness levels show greater autonomous motivation, higher current physical activity levels and higher physical activity levels nine months later. In addition, children who perceive their physical fitness more accurately show more current physical activity. Results indicate that the interplay between actual and perceived physical fitness does not only have an effect on physical activity but also on autonomous motivation, which is a predictor for long-term physical activity. Therefore, intervention should focus on the promotion of actual and perceived physical fitness. In addition, the ability to accurately assess fitness should be promoted in this age group.     

Exercise mode and executive function in older adults: An ERP study of task-switching

The purpose of this study was to investigate the relationship between exercise mode and executive function and its effect on behavior and neuroelectric activity. Forty-eight older adults were classified into open-skill, closed-skill, and irregular exercise groups based on their experience of exercise participation. Executive function was measured via a task-switching paradigm, in which the behavioral indices and event-related potentials elicited by task-switching were assessed. The results revealed that the exercise groups, regardless of the exercise mode, exhibited faster reaction times in both global and local switches than the irregular exercise group, regardless of the within-task conditions. Similarly, larger P3 amplitudes were observed in both exercise groups compared to the irregular exercise group. Moreover, additional facilitation effects of open-skill exercises on global switch costs were observed, whereas no differences in local switch costs were found among the three groups. The results replicate previous studies that have reported generally improved executive function after participation in exercises; additionally, they extend the current knowledge by indicating that these cognitive improvements in specific aspects of executive function could also be obtained from open-skill exercises.     

Aerobic exercise training ameliorates craving and inhibitory control in methamphetamine dependencies: A randomized controlled trial and event-related potential study

ObjectiveMethamphetamine (MA) usage has been recognized as a prominent substance-abuse issue. While exercise training reportedly improves fitness and mental status in the MA-dependent, how exercise training affects addiction and cognitive deficiency has yet to be established. The current study aimed to determine the effects of aerobic exercise training on both MA-associated cravings and inhibitory control among those with MA dependencies.DesignA 12-week randomized controlled trial.MethodSixty-two people with MA dependencies recruited through the Drug Rehabilitation Bureau were assigned to either an aerobic exercise or attentional control group, with 50 participants completing the trial. The aerobic exercise program involved three 30-min sessions of moderate-intensity exercise per week. Along with a pre-test assessment, craving levels were evaluated every three weeks, and data on neutral and MA-related inhibitory control as well as its elicited neuroelectric activation were collected at the end of the intervention.ResultsCompared with the control group, the exercise group experienced attenuated MA craving levels after 6 weeks of the exercise program, and the decreased trend was maintained until the termination of treatment. In the post-test, the exercise group also demonstrated more accuracy in behavioral inhibitory control as well as greater N2 amplitude in the Nogo condition of both the standard and MA-related tasks than those in the control group or pre-test.ConclusionsThe current study provides the first evidence that aerobic exercise training may be efficacious for MA-associated cravings and inhibitory control from behavioral and neuroelectric perspectives among MA-dependent individuals.     

Evaluating reading and metacognitive deficits in children and adolescents with attention deficit hyperactivity disorder

The reading achievement of children and adolescents with Attention Deficit Hyperactivity Disorder (ADHD) has scarcely been explored in research conducted in the Spanish language and when it has, the results have been contradictory. The focus of the present research is to analyze participants' reading competency and metacognitive strategies as they carry out reading comprehension tasks. The sample was comprised of 187 Argentine schoolchildren aged 9 to 13 years old. 94 constituted the control group and the clinical group consisted of 93 schoolchildren diagnosed with ADHD. The metacognitive assessment was made up of two metacognitive tests, the Reading Awareness Scale (ESCOLA; acronym in Spanish) and a Spanish adaptation of Metacognitive Awareness of Reading Strategies Inventory (MARSI), and one test of reading comprehension, the Evaluation of Reading Processes for Secondary Education Students (PROLEC-SE; acronym in Spanish). Students with ADHD had lower achievement on tests o reading comprehension compared to the control group. Nevertheless, our results suggest their difficulties did not stem from readin comprehension problems, but rather from alterations in their Executive Functions, because when subjects' reading comprehensio was equalized, students with ADHD still exhibited a lower level of Metacognition, particularly when it came to planning.     

Evaluation of pharmacological treatment of impulsivity in children with attention deficit hyperactivity disorder

We used an assessment that involved competing reinforcer dimensions in a concurrent-schedules arrangement to examine the effects of stimulant medication on impulsivity (i.e., sensitivity of choices to reinforcer immediacy relative to rate, quality, and effort) with 4 students with attention deficit hyperactivity disorder. The assessments were administered in the context of a double-blind, placebo-controlled, counterbalanced reversal design. Reinforcer immediacy was the most influential dimension for 3 of the students and the second most influential dimension for 1 of the students across placebo and medication conditions; medication did not affect these sensitivities.     

Visual exogenous and endogenous attention and visual memory in preschool children who stutter

PurposeAttention develops gradually from infancy to the preschool years and beyond. Exogenous attention, consisting of automatic responses to salient stimuli, develops in infancy, whereas endogenous attention, or voluntary attention, begins to develop later, in the preschool years. The purpose of this study was to examine (a) exogenous and endogenous attention in young children who stutter (CWS) and children who do not stutter (CWNS) through two conditions of a visual sustained selective attention task, and (b) visual short-term memory (STM) between groups within the context of this task.Method42 CWS and 42 CWNS, ages 3;0–5;5 (years;months), were pair-matched in age, gender (31 males, 11 females per group), and socioeconomic status. Children completed a visual tracking task (Track-It Task; Fisher et al., 2013) requiring sustained selective attention and engaging exogenous and endogenous processes. Following each item, children were asked to recall the item they had tracked, as a memory check.ResultsThe CWS group demonstrated significantly less accuracy in overall tracking and visual memory for the tracked stimuli, compared to the CWNS group. Across groups, the children performed better in sustained selective attention when the target stimuli were more salient (the condition tapping both exogenous and endogenous attention) than when stimuli were less so (the condition tapping primarily endogenous processes).ConclusionsRelative to peers, preschool-age CWS, as a group, display weaknesses in visual sustained selective attention and visual STM.     

Lack of inhibition: a motivational deficit in children with attention deficit/hyperactivity disorder and children with traumatic brain injury.

Recent research has demonstrated that both brain-injured children and children with attention deficit/hyperactivity disorder (ADHD) suffer from response inhibition deficits. To investigate whether these deficits can be influenced by motivational factors, the stop-signal task was performed with and without reward contingencies for successful inhibition. Three groups of children between 8 and 12 years of age, participated in the study: 31 children with ADHD, 37 with traumatic brain injuries (TBI), and 26 normal controls. Results indicated that, although all groups showed comparable learning effects, reward contingencies had different effects on the groups. Whereas the performance of children with ADHD under reward contingencies were brought up to the performance level of normal controls, rewards were found less effective at improving response inhibition in children with TBI. The results further support a motivational/energetic explanation of the inhibitory deficit in children with ADHD, and of a primary response inhibition deficit due to structural brain damage in children with TBI.     

The mediating role of neurocognitive functions in the relation between physical competencies and academic achievement of primary school children

Previous studies into associations between physical, neurocognitive and academic skills have reported inconsistent results. This study aimed to get more insight into these relations by examining all three domains simultaneously, testing a complete mediational model including measures of physical competencies (cardiovascular fitness and motor skills), neurocognitive skills (attention, information processing, and core executive functions), and academic achievement (reading, mathematics, and spelling). Dutch primary school students (n = 891, 440 boys, mean age 9.17 years) were assessed on the Shuttle Run Test (cardiovascular fitness), items of the Körperkoordinationstest für Kinder and Bruininks-Oseretsky Test-II (fundamental motor skills), computerized neurocognitive tests, and standardized academic achievement tests. A multilevel structural equation model showed that physical competencies were only indirectly related to academic achievement, via specific neurocognitive functions depending on the academic domain involved. Results provide important implications, highlighting the importance of well-developed physical competencies in children.