Autonomic Responses to Head-Up Tilt Test in Children with Autism Spectrum Disorders

Autism Spectrum Disorders (ASD) is a group of neurodevelopmental disorders often manifested by social and behavioral deficiencies. Autonomic dysfunction is frequently reported in the autistic population but the mechanisms remain largely unknown. We aimed to characterize the cardiac autonomic profile of children with autism during a head-up tilt test. Thirty-nine male children were recruited: 19 controls (9.9 ± 1.6 years) and 20 children with ASD without intellectual disability (10.7 ± 1.2 years). Each child underwent a head-up tilt test on a motorized tilt table. After a 10 min resting period in the supine position, subjects were tilted head-up to 70° on the table for 10 min. Heart rate and blood pressure variabilities were continuously recorded using non-invasive Nexfin monitoring. The head-up tilt test significantly altered heart rate variability (p < 0.001 for both groups) and greater parasympathetic responses were found in the ASD group compared to controls (p < 0.05). In the supine position baroreflex sensitivity was higher in children with ASD than in the controls (p < 0.05) and significantly decreased during the tilt test in the ASD group, but not in controls. Our results showed that children with ASD did not have clinical signs of dysautonomia in response to a head-up tilt test. However, in children with ASD higher parasympathetic responses with the same sympathetic modulations during orthostatic stress suggest parasympathetic dominance in this population.     

Psychosocial Factors Associated with Quality of Life Among Individuals Attending Genetic Counseling for Hereditary Cancer

The aim of this multicenter study was to explore associations between psychosocial factors (general self-efficacy, perceived availability of social support, cancer-related distress) and health-related quality of life, among individuals at risk for hereditary cancer. One-hundred and twenty one participants with a family history of breast-cancer or colorectal cancer answered a questionnaire 2-4 weeks prior to genetic counseling. The two dimensions of the health-related quality of life measure, mental and physical health were both used as outcome variables. Multiple regression (linear) analyses revealed that increasing degrees of cancer-related distress was related to decreasing degrees of mental health whereas increasing degrees of self-efficacy and social support were related to increasing degrees of this outcome variable. Self-efficacy, self-esteem support and tangible aid seemed to moderate the relationship between cancer-related distress and mental health. These results suggest that self-efficacy and certain resources of social support buffer the negative association between cancer-related distress and mental health, and might be suitable for interventional efforts. Implications for genetic counseling practice are discussed.     

Crafting a Better Life

This is a review of “The Craftsman” by Richard Sennett, published by Yale University Press, 2008.     

Factors Associated with Psychological Maladjustment of Mexican Adolescents Living in Poverty

The objectives of this study were to test the replicability of the Youth Self-Report structure in Mexican adolescents living in poverty; to determine gender and rurality differences in internalizing and externalizing problems; and to identify predictors of internalizing and externalizing problems. Data were collected from a probabilistic sample of households that are beneficiaries of the Oportunidades program, including the heads of those households, their spouses and their adolescent children. The self-reports of parents and children were analyzed using structural equation modeling. Results confirmed the Youth Self-Report structure in Mexican adolescents, and indicated higher levels of emotional disorders in females, higher levels of behavioral disorders in males, and higher levels in all the Youth Self-Report scales in rural adolescents. Internalizing and externalizing problems were mediated by the presence of loneliness, oppositional behavior and stress, through which the model’s other latent variables exerted indirect influence on the determination of youth psychopathology.     

Psychological Factors Associated with Emotional Responses to Receiving Genetic Risk Information

This study identified levels of distress, and predictors of levels of distress, in women undergoing assessment for genetic risk of breast/ovarian cancer based on their family history. It comprised a cohort study following 154 women who completed questionnaires at entry into a cancer genetic assessment programme and following risk provision. Independent significant associates of anxiety following risk provision were age, neuroticism, feeling hopeless about developing cancer, a perceived lack of control over developing cancer, lack of a social confidant, and a coping response involving acceptance/resignation. Depression was associated with age, neuroticism, feeling hopeless about developing cancer, lack of social confidant, and a coping response involving acceptance/resignation. To avoid high levels of psychological morbidity in future cohorts undergoing cancer genetic risk assessment, information should be given that emphasises that some degree of control over health outcomes through behaviour change or increased surveillance is possible.     

Psychological Factors Associated with Support for Suicide Bombing in the Muslim Diaspora

A robust literature on ingroup versus outgroup conflict suggests that perceived discrimination may be an important factor in intergroup aggression. Yet, to date, no studies have tested the hypothesis that the perception of being the victim of anti‐Muslim discrimination might be associated with support for anti‐Western political violence. We undertook an analysis of two Pew Global Attitudes Surveys: (1) a 2006 data set surveying 1,627 adult Muslim residents of Great Britain, France, Germany, and Spain and (2) a 2007 data surveying 1,050 adult Muslim residents of the United States. Our analyses support the conclusions that younger age and perceived discrimination are both associated with support of suicide bombing in these Muslim diaspora populations. Study 1 found that a bad experience of discrimination increased the odds of justifying suicide bombing among European Muslims by a factor of 3.4. Study 2 found that experienced discrimination was associated with justification of suicide bombing among American Muslims. If further investigations confirm that perceived discrimination is a risk factor for support for political violence, initiatives to reduce discrimination would theoretically reduce the risk of terrorism. We discuss the challenge of breaking the vicious cycle of intergroup prejudice and radicalization.     

Speech and Language Difficulties Along with Other Child and Family Factors Associated with Health Related Quality of Life of Australian Children

Speech and/or language difficulties (SaLD) can potentially compromise a child’s health-related quality-of-life (HRQoL). Very few studies have examined associations between SaLD, other child and family factors and HRQoL and none have been undertaken in Australia. We explore these associations using data from a nationally representative Australian sample of 4–5 year old children, extracted from the Longitudinal Study of Australian Children (LSAC) (n?=?4386). The Disability-Stress-Coping Model informed variable selection. Three domains of HRQoL were examined, and assessed on physical, emotional and social functioning subscales of the Pediatric Quality of Life Inventory (PedsQL). SaLD measures included parent concern about speech/language (Parents’ Evaluation of Developmental Status) and receptive vocabulary ability (adapted Peabody Picture Vocabulary Test-III). Multiple regression analyses revealed that various child and family factors representing all constructs from the Disability-Stress-Coping Model were significantly associated with HRQoL. Specifically, HRQoL was positively associated with parental warmth and child’s general health and negatively associated with parent speech/language concerns and maternal depression across all domains. Parents with concerns about their pre-school child’s speech and language rate the quality of their child’s health more poorly across physical, emotional and social domains. Associations between parent speech/language concerns and HRQoL were notable for being apparent in a (non-clinical) population sample and for persisting independent of factors such as maternal depression, parenting style and the child’s general health.     

癌症病人的生活质量及心理干预研究

本研究在前期研究的基础上进一步探讨癌症病人的生活质量状况和心理干预的效果。运用病例对照实验设计 ,选用生活质量问卷 (QLQ C3 0 )作为主要测查工具 ,采用两因素混合实验方差分析统计方法 ,对 1 2 0名住院化疗病人进行了比较分析。结果显示 :躯体功能 (PF)、角色功能 (RF)、情绪功能(EF)、认知功能 (CF)和整体生活质量 (QL)得分在治疗前后和实验与对照组之间的交互作用均显著和非常显著 ;症状量表和单项症状中交互作用显著和非常显著的有 :疲乏 (FA)、呼吸困难 (DY)、失眠 (SL)、食欲丧失 (AP)。因此 ,化疗对病人的生活质量有明显的影响 ,经心理干预后癌症病人的各种功能状况和症状得到不同程度的改善。     

Personality Factors Associated With Psychological Distress in Testicular Cancer Survivors

The aim of this study was to investigate symptoms of anxiety and depression in testicular cancer survivors (TCSs) and to identify personality traits associated with psychological distress in these patients by means of the MMPI (Hathaway &; McKinley, 1943 Hathaway, S. R. and McKinley, J. C. 1943. The Minnesota Multiphasic Personality Inventory, Minneapolis: University of Minnesota Press.  [Google Scholar]). A total of 50 TCSs and 50 age-adjusted healthy men participated in the study, and we used the following self-report instruments: Montgomery–Asberg Depression Rating Scale (Montgomery &; Asberg, 1979 Montgomery, S. and Åsberg, M. 1979. A new depression scale designed to be sensitive to change. British Journal of Psychiatry, 134: 382–389. [Crossref], [PubMed], [Web of Science ®] , [Google Scholar]), Hamilton Anxiety Rating Scale (Hamilton, 1959 Hamilton, M. 1959. The assessment of anxiety states by rating. British Journal of Medical Psychology, 32: 50–55. [Crossref], [PubMed], [Web of Science ®] , [Google Scholar], 1969 Hamilton, M. 1969. Diagnosis and rating of anxiety. British Journal of Psychiatry, 3: 76–79.  [Google Scholar]), Spielberger's State–Trait Anxiety Inventory (Spielberger, 1970 Spielberger, C. D. 1970. “Anxiety as an emotional state”. In Anxiety: Current trends in theory and research, Edited by: Spielberger, C. New York: Academic.  [Google Scholar], 2005 Spielberger, C. D. 2005. State–Trait Anxiety Inventory for adults, Redwood City, CA: Mind Garden.  [Google Scholar]), and the MMPI. TCSs displayed higher rates on all psychopathology scales studied compared to controls, but the majority of the patients' scores were within the “normal range,” indicating rather mild psychological distress. TCSs' MMPI profiles showed higher rates on Scales 1, 3, 6, and 9 compared to controls; and within the TCSs sample, symptoms of depression were most closely associated with Scales 3 and 5. Similarly, anxiety symptoms were mainly associated with Scale 3. These findings indicate that TCSs present mild symptoms of psychological distress, mainly anxiety and depressive symptoms, suggesting that careful assessment and consultation in TC patients is essential to help them deal with distress after treatment and to minimize possible risk factors.     

Hope as a Psychological Factor Affecting Quality of Life in Patients With Psoriasis

Clinical observations and medical reports indicate that psoriasis has a tremendous impact on patients’ lives, lowering their quality in many important areas. However, the vast majority of research deals only with health-related issues. This study aimed to compare the general quality of life of psoriasis patients and healthy volunteers by examining psychological variables thought to modify the quality of life. 42 patients with psoriasis and 42 healthy volunteers matched for gender, age and education level were tested. Flanagan Quality of Life Scale was used to evaluate general quality of life. Basic hope level was assessed with Basic Hope Inventory. Trait hope was estimated using Trait Hope Scale. Psoriasis Area Severity Index was used to assess the severity of the disease. Psoriasis patients have a significantly lower overall quality of life (p?=?0.05), modified by Physical and Material Well-being (p?=?0.01), Personal Development and Fulfillment (p?=?0.03), and Recreation (p?=?0.04). They also have lower levels of trait hope (p?=?0.04) and its agency component (p?=?0.01). There were moderate, negative significant correlations with basic hope and such components of quality of life as Physical and Material Well-being (p?=?0.03, r?=?? 0.34) and Relations with other People (p?=?0.02, r?=?? 0.35). These results support the hypothesis of a reduced general quality of life and trait hope in psoriatics. Thus, psychological help for people suffering from dermatological disorders might be as important as medical intervention. Basic hope can be treated as a resource in coping with these disorders and trait hope as a resource conducive to well-being.     

The Relationships Between Spiritual Well-Being,Quality of Life,and Psychological Factors Before Radiotherapy for Prostate Cancer

Journal of Religion and Health - Given shifting trends of religious identities in the USA, better understanding the impact of patients’ religious identities on health-related quality of life...     

Comparing Binary Transgender and Nonbinary People: Factors Associated with Psychological Well-Being Among a Predominately People of Color Sample

Binary transgender and nonbinary people face interpersonal and societal discrimination which can contribute to minority stress and negative mental health. Thus, it is important that family therapists understand what factors contribute to psychological well-being to be able to offer helpful and inclusive therapy services to these communities. This study addresses a gap in the literature regarding differences in factors contributing to psychological well-being between binary transgender and nonbinary people as well as understanding these factors in a predominantly People of Color (POC) sample. Utilizing secondary data from the Social Justice Sexuality Project (Battle and DeFreece in Women Gend Fam Color 2(1):1–31. https://doi.org/10.5406/womgenfamcol.2.1.0001, 2014; Battle et al. in Social justice sexuality survey: cumulative codebook, City University of New York-Graduate Center, New York, 2012), this study examined the relationships between perceived family support, religiosity, community connectedness and psychological well-being in a sample of binary transgender and nonbinary people. Results from a multiple group path analysis show that perceived family support, religiosity and being connected to an LGBT community were significantly associated with psychological well-being for binary transgender people, while only LGBT community connectedness was significantly associated with psychological well-being for nonbinary people. Implications for family therapists include helping families support binary transgender and nonbinary family members, deconstructing non-affirming religious messages about gender identity and connecting clients to affirmative religions and religious leaders, and being knowledgeable about community resources for binary transgender and nonbinary POC.

     

Optimism and Prostate Cancer-Specific Expectations Predict Better Quality of Life after Robotic Prostatectomy

We examined the relations among generalized positive expectations (optimism), prostate-cancer specific expectations, and prostate cancer-related quality of life in a prospective sample of 83 men who underwent robotic assisted laparoscopic prostatectomy (RALP) for prostate cancer. Optimism was significantly associated with higher prostate cancer-specific expectations, β = .36, p < .001. In addition, optimism and prostate cancer-specific expectations were independent prospective predictors of better scores on the following prostate cancer-related quality of life scales: Sexual Intimacy and Sexual Confidence; Masculine Self-Esteem (specific expectations only), Health Worry, Cancer Control, and Informed Decision Making (βs > .21, ps < .05). When considered simultaneously, both optimism and specific expectations contributed uniquely to better Health Worry and Cancer Control scores, optimism was a unique predictor of better Sexual Intimacy and Sexual Confidence scores, and specific expectations uniquely predicted higher scores on Informed Decision Making. Although optimism and prostate-cancer specific expectations are related, they contribute uniquely to several prostate cancer-related quality of life outcomes following RALP and may be important targets for quality of life research with this population.     

Patient and Partner Quality of Life and Psychosocial Adjustment Following Radical Prostatectomy

We prospectively examined differences in quality of life and psychosocial adjustment in 80 prostate cancer patients and their partners (n = 65) beginning before radical prostatectomy and proceeding across the first year postsurgery. Both members of the couple experienced significant changes associated with the patient's cancer, however their experiences differed in some regards. Patients experienced reprieve from emotional distress and negative affect immediately following surgery despite worsened physical functioning. Partner quality of life and psychosocial adjustment scores were generally more constant from presurgery to postsurgery, with improvements noted 1 year later. For both patients and partners, cancer-specific stress symptoms declined progressively over the year. We also obtained partial support for the effectiveness of a single-session communication intervention on patient social/family wellbeing and partner general stress. Findings have implications for patient and partner adjustment following radical prostatectomy, and attest to the importance of incorporating partner evaluations into psychosocial oncology research.     

Factors Associated with Psychological Distress among Women of African Descent at High Risk for BRCA Mutations

Little is known about psychological distress among women of African descent who are at high risk for a BRCA mutation. This is a group for whom breast cancer risk reduction is critical due to the group’s high rates of breast cancer mortality. Distress is important to consider as it may reduce the potential benefit of genetic counseling and negatively affect decision making related to risk reduction. The goals of the current study were to examine breast cancer-specific distress and depressive symptoms in women of African descent at who are at high risk for a BRCA mutation and to identify background factors associated with these outcomes. Participants were 148 high-risk African American and Caribbean women who were part of a larger study that offered participants BRCA counseling at no cost. Participants completed the Impact of Events Scale, which assessed breast cancer-specific distress, and the Center of Epidemiological Studies-Depression Scale, which assessed depressive symptoms. Results of analyses revealed that almost half of the sample achieved scores indicating high and clinically significant breast cancer-specific distress, while almost one-third had clinically significant depression scores. Results further showed that low income was significantly associated with cancer-specific distress, while having a cancer diagnosis was significantly associated with depressive symptoms. These results underscore the need for targeted psychological support throughout the genetic risk assessment process for this particular high-risk group.     

心理干预对产褥期精神障碍患者生活质量的影响

探讨心理干预对产褥期精神障碍患者生活质量的影响。将85例产褥期精神障碍患者随机分为研究组45例和对照组40例,两组均给予精神科常规护理,研究组在此基础上根据患者的具体情况,实施有针对性的心理护理干预。于心理护理干预后采用Hamilton抑郁量表（HAMD）、Hamilton焦虑量表（HAMA）和生存质量量表（SF－36...