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Cholesterol performs a number of important roles in normal brain functioning, including the formation of myelin sheaths and communication between cells, and it has been theorised that statin use could disrupt these roles leading to deficits in cognition. Relevant research was identified via the La Trobe University library SummonTM search tool, using search terms including “statin cognition,” “statins cognition,” “statin brain,” “cholesterol cognition,” “cholesterol brain,” and “statin adverse effects” in addition to examination of the reference lists of the retrieved research articles. Research was examined from the published literature across several different research modalities: systematic reviews and meta‐analyses, randomised control trials, cohort studies, and case reports. On the basis of the surveyed literature, it is not possible to indicate any consistent caution or limitation with regard to the use of statins and their effects upon cognitive functioning due to the contradictory and inconsistent results arising from this literature. In summary, it is not possible to conclusively determine whether there are either cognitive benefits or detriments associated with the use of the statins. The determination of the effect of these agents on neuropsychological functioning requires more methodologically controlled long‐term longitudinal follow‐up studies of these treatments due to the complex and multisystem effects of these agents.  相似文献   

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《Philosophical Papers》2012,41(1):55-68
Abstract

Temporal externalism (TE) is the thesis (defended by Jackman (1999)) that the contents of some of an indvidual's thoughts and utterances at time t may be determined by linguistic developments subsequent to t. TE has received little discussion so far, Brown (2000) and Stoneham (2002) being exceptions. I defend TE by arguing that it solves several related problems concerning the extension of natural kind terms in scientifically ignorant communities. Gary Ebbs (2000) argues that no theory can reconcile our ordinary, practical judgments of sameness of extension over time with the claim that linguistic usage determines word extensions. I argue that Ebbs shows at most that no theory other than TE can effect this reconciliation. Furthermore, while Ebbs' argument undermines Jessica Brown's solutions to two closely related problems about natural kind term extensions (Brown 1998), TE can solve both problems without difficulty. Some criticisms of TE are briefly addressed as well.  相似文献   

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This article reviews the literature related to studies measuring various cognitive properties in suicidal patients. It provides a structural framework with which to classify the studies, and employs the categories of suicidal logic, cognitive style, social cognition, and cognitive control. The methodological issues discussed include: sample characteristics, operational definitions of suicidal behaviors, use of appropriate control groups, and the temporal nature of assessment. Improvements in experimental design are suggested for use in future research.  相似文献   

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社会认知的理论模型综述   总被引:15,自引:1,他引:14  
王沛  林崇德 《心理科学》2002,25(1):73-75
社会认知一般涉及社会信息的辨别、归类、采择、判断、推理等心理成分,即林崇德所提出的涉及人对社会性客体之间的关系等的认知,以及对这种认知与人的社会行为之间的关系的理解和推断。关于社会认知的近期研究探讨了人们关于群体及其成员的知识是如何在记忆中表征以及该知识是如何在后继判断过程中使用等问题,并且形成了一些具有代表性的理论模型。  相似文献   

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20世纪末期兴起的内隐社会认知研究,从揭示社会认知无意识成分的角度。为探究社会心理的实质提供了新思路。该文就内隐社会认知的理论发展及其研究方法沿革进行综述,并对国内该领域研究的社会意义及应用价值做一述评。  相似文献   

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Displacement of the cerebellar tonsils in Chiari type I malformation (CMI) can affect functions controlled by the cerebellum and brainstem. While playing an integral role in the control of movement, the cerebellum also has widespread cortical connections, influencing a range of cognitive process. A systematic literature review was conducted to examine the relationship between cognition and CMI, assessing evidence for general or domain-specific cognitive change. The search protocol examined the AMED, CINAHL, Cochrane Library, EMBASE, MEDLINE, PsycINFO, and Scopus databases. Articles meeting the following criteria were included in this review (i) examined children or adults with a clinically defined diagnosis of CMI, (ii) assessed cognitive function with a prospective examination, (iii) included at least one standardized instrument designed to measure general or specific domains of cognitive function, and (iv) were published in English in a peer-reviewed journal. Twelve articles were identified, including 783 cases aged 3 months to 64 years. General cognition, processing speed, and learning and memory appeared less affected, while language deficits appeared to diminish with age. Executive dysfunction was the most commonly reported cognitive impairment, while attention and working memory, and visuospatial and perceptual skills also appeared vulnerable. Numerous methodological limitations were identified that should be considered in interpreting the impact of CMI and planning future investigations. Overall, there is currently insufficient evidence to describe a valid and reliable profile of cognitive impairment in CMI. Further research is required to confirm these preliminary psychometric results and integrate them with pathophysiological models  相似文献   

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Little is known about the combined effects of aging and alcoholism on cognitive function, in spite of the potential importance of this knowledge. Studies reported to date have focused on whether aging and alcoholism have shared mechanisms (i.e., the premature aging hypothesis) or independent mechanisms. Most have concluded that the effects of aging and alcoholism on cognition operate through independent mechanisms. However, there are reasons to doubt this conclusion. Many of the studies were not optimally designed to discover shared mechanisms because they used a limited range of ages, included several different groups in their analyses, or had low statistical power. Furthermore, interpretation of the patterns of main effects and interactions between aging and alcoholism is not straightforward. Assumptions must be made about the nature of the impairments in order to interpret the data. This review uses several theories of cognitive aging as an organizing heuristic for interpreting the extant data on aging, cognition, and alcoholism. Some potential shared mechanisms for cognitive deficits in aging and alcoholism are identified, such as information processing speed and proactive interference in working memory. In contrast, some potential independent mechanisms are also identified, such as decay from working and long-term memory. These mechanisms should be used as a base to guide necessary further research.  相似文献   

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内部工作模型、护送模型、相关模型从不同侧重点出发,为儿童的社会关系认知研究提供了各自的理论基础.对儿童的社会关系认知研究有必要多情境、多维度地综合考虑,以期整合、动态地揭示儿童社会关系认知的发展规律.  相似文献   

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作为人类古老现象的权力,却是社会心理学的一个崭新课题。近年来,社会心理学家从社会认知的视角对权力心理进行了很多具有启发性的研究。理论和实证研究表明,权力的存在或激发广泛地影响了个体有意和无意的社会认知、情绪和社会行为,这些心理和行为既包含消极的成分,也包含中性和积极的成分。文章指出了权力心理学具有“强调社会认知、基础认知甚至神经机制”等特点和趋势。  相似文献   

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Cognitive dysfunction is highly prevalent, disabling, and poorly-managed in persons with multiple sclerosis (MS). Recent evidence suggests that exercise might have beneficial effects on cognition in this population. The current systematic, evidence-based review examined the existing literature on exercise, physical activity, and physical fitness effects on cognition in MS to accurately describe the current status of the field, offer recommendations for clinicians, and identify study-specific and participant-specific characteristics for providing future direction for ongoing MS research. We performed an open-dated search of Medline, PsychInfo, and CINAHL in December 2015. The search strategy involved using the terms ‘exercise’ OR ‘physical activity’ OR ‘physical fitness’ OR ‘aerobic’ OR ‘resistance’ OR ‘balance’ OR ‘walking’ OR ‘yoga’ OR ‘training’ OR ‘rehabilitation’ AND ‘multiple sclerosis’. Articles were eliminated from the systematic review if it was a review article, theoretical paper, or textbook chapter; did not involve persons with MS; involved only persons with pediatric-onset MS; did not involve neuropsychological outcomes; did not include empirical data to evaluate outcomes; involved pharmacological interventions; or was not available in English. The selected articles were first classified as examining exercise, physical activity, or physical fitness, and were then randomly assigned to 2 independent reviewers who rated each article for level of evidence based on American Academy of Neurology criteria. Reviewers further completed a table to characterize important elements of each study (i.e., intervention characteristics), the cognitive domain(s) that were targeted, participant-specific characteristics, outcome measures, and study results. The present review resulted in 26 studies on the effects of exercise, physical activity, and physical fitness on cognition in persons with MS. This included 1 Class I study, 3 Class II studies, 8 Class III studies, and 14 Class IV studies. Of the 26 total studies, 6 were randomized controlled trials. Overall, there is conflicting evidence for the effects of exercise on cognition in MS, and overall positive, but not definitive evidence for the effects of physical activity and physical fitness, respectively, on cognition in this population. Collectively, there is insufficient well-designed research to definitively conclude that exercise, physical activity, and physical fitness are effective for improving cognition in MS. This is based, in part, on methodological issues of Class I and II studies, such as inclusion of cognition as a secondary outcome (35 % of reviewed studies), poorly-developed exercise interventions, and paucity of research that included cognitively-impaired MS samples. However, promising evidence from Class III and Class IV studies may be useful for informing the development of better intervention research.  相似文献   

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随着心理无意识研究在记忆、学习和思维等领域的兴起,内隐时间认知也逐步成为时间心理学中的一个研究热点。本文分析了探究内隐时间认知的四种方法:分离范式、序列学习范式、表征动量范式和计时分布相关范式,指出内隐时间认知实验范式在无意识时间人格与社会心理学中的研究也是有相当前景的。  相似文献   

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脑功能定位在社会认知研究中的作用及其启示   总被引:4,自引:0,他引:4  
王沛  张国礼 《心理科学》2005,28(1):135-137
本文阐述了脑功能定位的具体技术及其与社会心理现象相结合的心理神经模型。这种结合的趋势有助于促进神经科学和社会心理学的发展,有助于解释社会心理现象中固有的一些具体问题。同时,由于社会心理现象的复杂性,因此并不一定都适合直接进行脑功能定位。  相似文献   

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自我的内隐社会认知研究   总被引:1,自引:0,他引:1  
自我的内隐社会认知研究具备坚实的理论基础,又有严格的实证研究方法,可以促进自我理论的深入发展。目前,内隐社会认知的自我研究已经成为自我研究的新生力量。文章最后对该取向的意义和趋势作了展望。  相似文献   

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Although the incidence of HIV in the United States is higher among men compared to women, the global proportion of women versus men who are infected has been approximately 50% since the late 1990s. Women have been under-represented in neuropsychological studies of HIV. A small number of studies have reported a significantly higher prevalence of neurocognitive impairment among HIV+ women compared to HIV− controls regardless of symptom status and with or without an AIDS diagnosis. Impairment was most evident on psychomotor tasks. The risk of neuropsychological impairment was increased among HIV+ women not on antiretroviral therapy. Age and depressive symptoms also increase neurocognitive risk. New neurocognitive studies of ovarian steroid hormones, PTSD and other psychiatric conditions are critical for addressing potential female-specific aspects of HIV-Associated Neurocognitive Disorder. Such studies will also address questions regarding involvement of the hippocampus and verbal memory, which may be of particular significance among HIV+ women.
Pauline M. MakiEmail:
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Cognition,construction of knowledge,and teaching   总被引:24,自引:0,他引:24  
The existence of objective knowledge and the possibility of communicating it by means of language have traditionally been taken for granted by educators. Recent developments in the philosophy of science and the historical study of scientific accomplishments have deprived these presuppositions of their former plausibility. Sooner or later, this must have an effect on the teaching of science. In this paper I am presenting a brief outline of an alternative theory of knowing that takes into account the thinking organism's cognitive isolation from reality. This orientation was proposed by Vico at the beginning of the 18th century, disregarded for two hundred years, and then propounded independently by Piaget as a developmentally grounded constructivist epistemology. The paper focuses specifically on the adaptive function of cognition, Piaget's scheme theory, the process of communication, and the subjective perspective on social interaction. In the concluding section it then suggests some of the consequences the shift of epistemological presuppositions might have for the practice of teaching.The only truly ubiquitous factor in cognitive developments — be it in the history of science or in the ontogeny of mind — are of a functional, not a structural kind.Piaget and Garcia, 1983, p. 38I am indebted to Jack Lochhead and John Clement for their helpful critical comments on the draft of this paper. The work that led to it was supported in part by NSF Grants to IBR. University of Georgia, and SRRI, University of Massachusetts.  相似文献   

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