Karen Horney's biocultural dialectic

The function of these [neurotic] trends can be better understood if we take a look at their genesis. They develop early in life through the combined effect of given temperamental and environmental influences. Whether a child becomes submissive or rebellious under the pressure of parental coercion depends not only on the nature of the coercion but also on given qualities, such as the degree of his vitality, the relative softness or hardness of his nature.Since we we know less of the constitutional factors than of the environmental ones, and since the latter are the only ones susceptible of change, I shall comment only on these. (Karen Horney,Self-Analysis. New York: Norton, 1942. Emphasis added)