Computational analyses in cognitive neuroscience: in defense of biological implausibility

Because cognitive neuroscience researchers attempt to understand the human mind by bridging behavior and brain, they expect computational analyses to be biologically plausible. In this paper, biologicallyimplausible computational analyses are shown to have critical and essential roles in the various stages and domains of cognitive neuroscience research. Specifically, biologically implausible computational analyses can contribute to (1) understanding and characterizing the problem that is being studied, (2) examining the availability of information and its representation, and (3) evaluating and understanding the neuronal solution. In the context of the distinct types of contributions made by certain computational analyses, the biological plausibility of those analyses is altogether irrelevant. These biologically implausible models are nevertheless relevant and important for biologically driven research.     

Self-awareness: behavior analysis and neuroscience

Self-awareness is a specific type of autoclitic discriminative behavior and inferential generalization to similar performances exhibited by other people. Brain imaging findings take on special importance within behavior analysis when they indicate that dysfunctions in these areas are related to differential effects of our interventions, with some acquiring substantially typical self-awareness skills and others failing to do so. It appears that those individuals whose brain dysfunctions are limited to these areas, and are not part of more generalized brain abnormalities, are amenable to substantial acquisition of those most basic of human skills called self-awareness, whereas individuals with more generalized brain dysfunction are not so disposed. Through a combination of less or more effective teaching contingencies during childhood, and degrees of dysfunction of those brain structures, some children grow up lacking self-reflective abilities and self-insight, whereas others are extraordinarily astute at those capacities. Among children with autism spectrum disorders who lack those skills due to abnormal brain development, approximately half of them can acquire those skills, at least to some degree through the use of effective, intensive, early behavior therapy methods.     

Structures,dynamics and mechanisms in neuroscience: an integrative account

Proponents of mechanistic explanations have recently proclaimed that all explanations in the neurosciences appeal to mechanisms. The purpose of the paper is to critically assess this statement and to develop an integrative account that connects a large range of both mechanistic and dynamical explanations. I develop and defend four theses about the relationship between dynamical and mechanistic explanations: that dynamical explanations are structurally grounded, that they are multiply realizable, possess realizing mechanisms and provide a powerful top-down heuristic. Four examples shall support my points: the harmonic oscillator, the Haken–Kelso–Bunz model of bimanual coordination, the Watt governor and the Gierer–Meinhardt model of biological pattern formation. I also develop the picture of “horizontal” and “vertical” directions of explanations to illustrate the different perspectives of the dynamical and mechanistic approach as well as their potential integration by means of intersection points.     

Integrating psychology and neuroscience: functional analyses as mechanism sketches

We sketch a framework for building a unified science of cognition. This unification is achieved by showing how functional analyses of cognitive capacities can be integrated with the multilevel mechanistic explanations of neural systems. The core idea is that functional analyses are sketches of mechanisms, in which some structural aspects of a mechanistic explanation are omitted. Once the missing aspects are filled in, a functional analysis turns into a full-blown mechanistic explanation. By this process, functional analyses are seamlessly integrated with multilevel mechanistic explanations.     

Introduction to the special section on social neuroscience: promise and caveats

This special issue of the Journal of Personality and Social Psychology: Attitudes and Social Cognition is devoted to theory and research at the interface of social psychology and neuroscience. The 5 empirical articles represent the theoretical and methodological breadth of issues considered by social neuroscientists. The methods span brain lesion work to neuroendocrinology to psychophysiological indicators of brain activity to functional magnetic resonance imaging indicators of brain activity. The remaining 2 articles consider explicitly some of the promises and pitfalls of social neuroscience; these authors, although noting the power of neuroscience methods, remind readers of the serious challenges posed in trying to examine the biological processes underlying or associated with social psychological phenomena. These articles help to reveal the richness of social neuroscience and the power of neuroscientific methods to address processes and mechanisms that would not be possible with traditional social psychology methods.     

Effects of alcohol on person perception: a social cognitive neuroscience approach

The acute effects of alcohol on cognitive processing of expectancy violations were investigated using event-related brain potentials and a cued recall task to index attentional and working memory processes associated with inconsistency resolution. As predicted, expectancy-violating behaviors elicited larger late positive potentials (LPP) and were recalled better than expectancy-consistent behaviors. These effects were moderated by alcohol and the valence of initial expectancies. For placebo group participants, positive targets performing negative behaviors elicited the largest LPP responses and were recalled best. For those in the alcohol groups, negative targets behaving positively elicited the largest LPP and recall responses. These findings suggest that alcohol does not globally impair working memory processes in person perception but instead changes the nature of valenced information processing. Findings are discussed in the context of alcohol's effects on working memory processes, reward sensitivity, and the prefrontal cortical structures thought to mediate them.     

Being imitated, conformity, and social influence: An integrative review

The recently developed literature on the effects of being imitated and the social influence function of imitation are reviewed, as is related literature on conformity from social psychology. Then, this research is considered within a number of theoretical contexts, but especially within the conceptual framework of Byrne's elaboration of effectance motivation. Finally, questions are raised which need to be addressed in future research.     

Unfixed action patterns: social behavior and the brain

The 2000 Karger Workshop: ‘Social Modulation of Brain and Behavior’, New Orleans, LA, USA, 3 November 2000.     

Models of human social behavior and their application to health psychology

Abstract

Theoretical models popular in the health domain differ in level of generality. Some were developed to deal with any human social behavior and then applied to health psychology, others were specifically designed to deal with health-related issues. Content-specific theories, such as the health-belief model and the perceptual-cognitive approach, outline in detail factors relevant for our understanding of health-related beliefs and actions. In contrast, it is only in the course of empirical research that content-free models, such as social cognitive theory and the theory of planned behavior, obtain the specific information required for understanding. Their advantage lies in their applicability across behavioral domains. Whether content-specific or content-free, the major utility of models developed to date has been to organize and communicate knowledge about health-related behavior. Few profound insights have as yet resulted from their application, with the possible exception of the recognition that self-regulation, and especially self-efficacy, plays a major role in all aspects of health, illness, and recovery.     

Alcohol and social behavior II: the helpful drunkard

Can alcohol make people more helpful, and if so, how? We hypothesized that alcohol would increase helping when, if the person were sober, the helping response would be under high inhibitory conflict--that is, when it would be affected by strong instigating and inhibiting pressures. Alcohol's damage to inhibitory processing should then allow instigating pressures to have more influence on the response, increasing helping. We expected that under low inhibitory conflict, when either or both of these response pressures would be weak under sobriety, alcohol would have little effect on helping. In two experiments we examined this reasoning. In Study 1, a mild dose of alcohol increased helping among high-conflict subjects pressured to help with a task they did not like, but did not increase helping among low-conflict subjects who either liked the task or were weakly pressured to help. In Study 2, a somewhat stronger dose of alcohol increased helping among all high-conflict subjects pressured to help with an undesirable task, yet again had no effect among low-conflict subjects weakly pressured to help. These studies provided an experimental demonstration of the role of inhibitory response conflict in mediating alcohol's social effects, and show that this process generalizes to prosocial behavior. Additional evidence from both experiments helped to rule out alternative explanations concerning drinking expectancies, alcohol's ability to enhance mood, and its ability to make the task more bearable.     

Driven by distraction: An integrative review of social facilitation theory and research

Social facilitation refers to the enhancement of an organism's dominant responses by the simple physical presence of species-mates, independent of any informational or interactional influences the others may exert. This phenomenon represents the consequences of the most elementary transition from a nonsocial to a social environment, and is one of the first research areas in experimental social psychology. The present analysis examines the status of three different explanations for socially facilitated behavior. Substantial weaknesses exist in the propositions that the presence of others elicits a reflexive alertness or preparedness response (Mere Presence) and that the presence of others increases drive through classically conditioned anticipations of positive and negative outcomes (Learned Drive). A third proposition argues for increased drive due to response conflict involving incompatible tendencies to attend to others and to ongoing task requirements (Distraction/Conflict). The basic assumptions of the Distraction/Conflict hypothesis are found to have considerable empirical support, and a wide variety of apparently anamolous results are integrated into the attentional conflict framework. Finally, a synthesis of the three approaches is proposed wherein slightly modified versions of the Mere Presence and Learned Drive theories serve to specify two common antecedents for the arousal of attentional conflict (the Attentional Processes model). Connections between the Attentional Processes model and past and future research are explored.     

Comparisons in research and reasoning: Toward an integrative theory of social induction

Strong scientific theories give coherence to a body of research findings, make precise predictions about key phenomena, and guide the search for new discoveries. In social psychology, some contemporary theories fall short of this ideal. Mini-theories are prevalent (cf. Van Lange, Higgins, & Kruglanski, 2011), many predictions are merely directional (like this one!) and theorizing post-hoc. Guided by experimental reasoning, many researchers emphasize—and reify—empirical differences. Taking the experimental method as an epistemological gold standard, they regard comparative thinking as a criterion of rational thinking. Using examples from social judgment and decision making, we show how comparative reasoning can constrain theoretical development and bias assessments of human rationality. To encourage movement toward stronger theory, we describe a model of inductive reasoning in social contexts.     

Understanding biological and social influences on religious affiliation, attitudes, and behaviors: a behavior genetic perspective

Although the transmission of religiousness has been assumed to be purely cultural, behavior genetic studies have demonstrated that genetic factors play a role in the individual differences in some religious traits. This article reviews the extant behavior genetic literature and presents new analyses from the "Virginia 30,000" on the causes of variation in religious affiliation, attitudes, and practices, and relates these to personality as construed by Eysenck. Results indicate that religious affiliation is primarily a culturally transmitted phenomenon, whereas religious attitudes and practices are moderately influenced by genetic factors. Further, Eysenck's personality traits do not mediate genetic influences on religiousness, but significant negative genetic correlations are found between church attendance and liberal sexual attitudes. Implications and possibilities for future studies are discussed.     

On the social nature of global self-esteem: a replication study

Few researchers have considered the relationship between global self-esteem and the reflected appraisal of others in one's life, or how reflected appraisals and global self-esteem may change as a result of interpersonal feedback. In this study, the authors collected data from 110 undergraduate students on (a) their global self-esteem and the reflected appraisals of multiple others in their lives and (b) how these dimensions changed in hypothetical interpersonal-feedback situations. Results showed that participants' global self-esteem was related to the reflected appraisals of their fathers, teachers, and friends. The results also indicated that others' reflected appraisals and the individual's global self-esteem fluctuated according to the nature (i.e., positive vs. negative) of the hypothetical interpersonal feedback. Overall, the findings emphasize the social nature and regulation of global self-esteem.     

A systems neuroscience approach to autism: biological,cognitive, and clinical perspectives

Autism is a behaviorally defined disorder characterized by a broad constellation of symptoms. Numerous studies directed to the biological substrate demonstrate clear effects of neurodevelopmental differences that will likely point to the etiology, course, and long-term outcomes of the disorder. Consistently replicated research on the neural underpinnings of autism is reviewed. In general, results suggest several main conclusions: First, autism is a heterogeneous disorder and is likely to have multiple possible etiologies; second, structural brain studies have indicated a variety of diffuse anatomical differences, reflective of an early developmental change in the growth or pruning of neural tissue, rather than localized lesions; similarly, neurochemical studies suggest early, neuromodulatory discrepancies rather than gross or localized abnormalities; and finally, there are a number of limitations on studies of brain activity that to date preclude definitive answers to questions of how the brain functions differently in autism. The large number of active research programs investigating the cognitive neuroscience of autism spectrum disorders, in combination with the exciting development of new methodologies and tools in this area, indicates the drama and excitement of work in this area.