项目竞争强度对网络成瘾大学生提取诱发遗忘的影响

执行功能缺陷是网络成瘾发生、维持和复发的原因之一,以往研究侧重于探讨网络成瘾者注意控制、反应抑制等执行功能成分的损伤状况,而其记忆抑制状况尚不清楚。本研究通过考察网络成瘾大学生的提取诱发遗忘（RIF）来探讨其记忆抑制的特点及RIF的产生机制。结果发现：低网络成瘾个体在高项目竞争强度下表现出显著的RIF,在低项目竞争强度下未产生;高网络成瘾个体在低项目竞争强度下表现出显著的RIF,在高项目竞争强度下未产生。结果表明网络成瘾大学生的记忆抑制能力受损严重,其在低项目竞争强度下易受相关代价与效益问题（CCB）影响而产生干扰性RIF。     

智能手机成瘾者的注意执行控制功能:心智游移的作用

智能手机成瘾可能会影响个体的注意执行控制功能,以往研究结果在该影响是否取决于实验刺激与成瘾物的相关性上存在不一致,研究关注心智游移在其中的作用。采取《大学生智能手机成瘾量表》筛选被试90人分为成瘾组和非成瘾组。实验一采用反应的持续注意任务考察不同水平智能手机成瘾者的心智游移特点,采用《白日梦量表》辅助研究,结果发现智能手机成瘾被试量表得分显著更高,在实验中更多地评估任务表现,且其心智游移与偶然性的任务疏忽、一般性任务疏忽以及反应分离状态有关。实验二采用AX版本的持续操作任务探究智能手机成瘾者的注意执行控制功能中心智游移的调节作用,结果发现高频心智游移的智能手机成瘾者比低频心智游移的智能手机成瘾者维持目标更困难。研究对于理解智能手机成瘾对个体认知的影响具有一定的启示作用。     

易感人格的工作记忆特征对药物成瘾的调节机制

药物成瘾是指持续使用成瘾药物, 出现耐受性和戒断症状并严重阻碍正常社会功能的精神疾病。工作记忆在调节药物成瘾行为中扮演了中心角色：在神经易感性和易感人格特质基础上, 低工作记忆容量导致危险决策和去抑制性, 进而影响寻求药物和复吸行为。目前的研究基于已经产生成瘾的个体, 无法区别神经易感性、人格特质以及工作记忆缺陷是药物成瘾的原因还是结果; 而且, 仅从认知角度研究药物成瘾的原因, 会忽视该行为受多个因素影响的事实。     

工作记忆训练对药物成瘾者认知功能的改善及其机制

对处于戒断期的各类药物成瘾群体进行认知训练，训练后药物成瘾个体认知能力得到改善，成瘾症状也得到了一定缓解。认知训练能够加速药物成瘾者大脑受损区域的自发性恢复，尤其是使影响个体抑制控制能力的中脑边缘多巴胺系统和前额叶系统发生功能性和结构性的积极变化，实现药物成瘾个体高级认知能力的改善。今后可以从不同类别的药物成瘾是否全部具有可逆性，设置的认知训练任务能否起到改善认知能力的效果，药物成瘾个体训练的性别差异以及训练效果的保持时间等角度进行研究。     

反应抑制的训练:内容、效果与机制

近期的研究发现,个体的反应抑制能力具有一定的可塑性。研究者多采用双盲随机对照实验设计,训练的对象包括儿童、成人和特殊群体,研究者通过Go/Nogo、Stop-signal等任务进行为期1周至3周,45至7200试次不等的抑制控制能力训练,并结合行为、脑电以及脑成像等技术对训练效果进行评估,研究结果发现,接受了抑制控制训练的个体其抑制能力得到提升,并伴随脑神经活动的变化。另外,研究者发现,抑制控制能力的训练效果还可以迁移至个体日常生活中的表现。但是,也有些研究并未发现抑制控制训练的效果。训练任务的设置,评估任务的选择以及被试反应策略的差异等因素可能会影响训练的效果。抑制控制训练引发行为与大脑活动的变化可能是由于训练导致了个体建立了自上而下有意识的抑制控制模式和自下而上的自动抑制模式。反应抑制和冲突抑制可塑性的比较,儿童与老年人抑制功能的训练以及训练效果的追踪研究将成为该领域日后研究的重点问题。     

冲动性对不同成瘾行为发展的调控及其神经机制

近年来越来越多的研究证据提示, 个体冲动性在成瘾疾患发生发展机制中具有关键作用, 可能成为成瘾行为的潜在易感标记以及早期识别和干预的重要靶点, 但冲动性对不同成瘾行为变化发展的调控机制尚不明确。项目拟综合跨成瘾谱系比较、纵向追踪设计、冲动行为干预等研究途径, 采用人格测量、神经认知、神经影像等技术, 首先比较尼古丁依赖者与网络游戏成瘾者的冲动性结构及其在前额叶–纹状体环路的结构功能改变; 然后采用混合分组设计筛选出具有高低冲动性的非成瘾青少年进行连续追踪研究, 考察冲动性对尼古丁依赖与网络游戏成瘾的预测效力; 并采用认知行为训练, 对吸烟成瘾者与网络游戏成瘾者进行冲动干预, 考察行为干预对冲动性水平及前额叶–纹状体环路功能的改变, 以及对不同成瘾行为发展的抑制后效。旨在探索冲动性作为成瘾的潜在易感标记及干预靶点的效力。     

基于驱动与控制相互作用的成瘾冲动性结构与机制

物质成瘾者具有明显的冲动性特征, 表现为难以戒断的成瘾物质使用。这种行为的产生除了抑制控制的问题外, 源于多个维度的驱动力也是重要的原因。低弱的抑制力无法抵挡驱力的作用, 出现不平衡状态, 形成难以控制的渴求下的强迫性用药或习惯性用药行为倾向。驱动力来源于多方面, 奖赏效应, 通过条件作用形成的S-R式相关线索反应以及感觉寻求等人格特质; 控制成分则包括了反应抑制与无法延迟满足的执行控制功能。     

经颅直流电刺激对健康人群反应抑制的影响

反应抑制是指抑制不恰当的或不符合当前需要的行为的能力, 研究表明反应抑制主要与额下回、背外侧前额叶和前辅助运动区的功能有关。经颅直流电刺激(tDCS)是一种非侵入式脑刺激技术, 近年来对健康人群使用tDCS刺激相应脑区从而影响反应抑制功能的研究日益增多, 但主要研究结果不一致。阐明tDCS影响反应抑制具体的神经机制、减少tDCS研究的异质性、探索更有效的tDCS刺激方式和确定tDCS效果的年龄依赖性差异已成为目前亟待解决的问题。     

吸烟对反应抑制的影响:证据、原因和争论

近期研究发现,吸烟会使个体的反应抑制能力受到一定程度的影响。与不吸烟的健康人群相比,吸烟者在测量反应抑制能力的Go/No Go任务和Stop-Signal任务上的虚报率较高,反应时间较长;吸烟者的反应抑制能力在反应抑制加工阶段受到影响,而在冲突监控阶段并未与正常被试表现出差异;另外,研究还发现,与不吸烟者相比,吸烟者左侧丘脑、左侧额中回和左侧前扣带回灰质体积较小。尼古丁的摄入对前额叶和中脑边缘多巴胺系统的影响可能是导致吸烟者反应抑制能力受到影响的原因。但是,一些研究并未发现吸烟对反应抑制能力存在影响,这可能与实验任务以及研究对象的选取有关。比较不同香烟剥夺状态下个体的反应抑制能力、比较吸烟者与其他药物成瘾者(酒精、毒品)反应抑制能力的差异并且比较使用双选择oddball范式与Go/No Go任务和Stop-Signal任务在对吸烟者反应抑制能力的研究上所得结果的异同以及对吸烟者反应抑制能力的干预和训练将成为该领域日后研究的重点。     

大学生网络成瘾的同伴传染：一项社会网络分析研究

以大二到大四475名大学生为被试,采用中文网络成瘾量表(CIAS-R)及同伴提名法测量其网络成瘾情况及人际关系网络特征指标,考察大学生网络成瘾的同伴影响。结果显示：(1)男生比女生更多居于同伴团体的中心位置,且与他人的“距离”更近;(2)标准化入接近中心度对个体网络成瘾有显著的负向预测作用,表明个体越处在人际网络中心,越不容易网络成瘾;(3)同伴团体网络成瘾对个体网络成瘾有显著正向预测作用。个体人际关系网络特征对网络成瘾的同伴传染调节效应不显著,即不论个体社交地位如何,网络成瘾的同伴影响不存在显著差异。由此推论,良好的同伴关系是个体网络成瘾的保护因素,网络成瘾存在同伴传染效应。     

Is Clinical Anxiety a Risk or a Protective Factor for Executive Functioning in Youth with ADHD? A Meta-regression Analysis

Comorbidity rates between ADHD and anxiety disorders (AD) are high, but little is known about the nature of this co-occurrence. A dominant idea is that AD may intensify some (i.e., attention and working memory) and attenuate other (i.e., inhibition) ADHD symptoms. Results are mixed, potentially because of between-study differences. To investigate this further we performed a meta-regression analysis on 11 studies (n ‘ADHD-only’ = 695; n ‘ADHD + AD’ = 608), containing 35 effect sizes on attention, inhibition and working memory. Main results were: (1) no evidence of a negative effect of AD on attention and working memory; (2) better response inhibition in children with ADHD with AD than those with only ADHD (medium ES g = ? .40); (3) medication moderated this association: the effect seemed limited to studies that included medication-naïve participants; (4) the difference between the two groups increased with age for attention and with proportion of boys for working memory ability. There was no effect of comorbid disruptive behavior disorder. In conclusion, AD seems to be a protective factor for inhibition problems as assessed with laboratory tasks in ADHD, especially in children who are medication naïve. Further, AD may have a protective function for attention in older children, and for working memory in boys with ADHD. It is therefore important to screen for AD when diagnosing ADHD, and to educate those with comorbid AD about the possible positive function of feeling anxious. Potential negative effects of ADHD medication on inhibition in children with comorbid AD should be considered.     

Examining the costs and benefits of inhibition in memory retrieval

Inhibitory control is thought to serve an adaptive function in controlling behavior, with individual differences predicting variation in numerous cognitive functions. However, inhibition is more properly construed as inducing both benefits and costs to performance. Benefits arise at the point when inhibition prevents expression of an unwanted or contextually inappropriate response; costs arise later, when access to the inhibited representation is required by other processes. Here we illustrate how failure to consider both the costs and benefits of inhibition has generated confusion in the literature on individual differences in cognitive control. Using retrieval-induced forgetting as a model case, we illustrate this by showing that changing the way that retrieval-induced forgetting is measured to allow greater expression of the benefits of inhibition together with the costs can reduce and even reverse the theoretically predicted correlation between motor and memory inhibition. Specifically, we show that when the final test in a retrieval-induced forgetting procedure employs item-specific cues (i.e., category-plus-stem cued recall and item-recognition) that better isolate the lingering costs of inhibition, better motor response inhibition (faster stop-signal reaction times) predicts greater retrieval-induced forgetting. In striking contrast, when the final test is less well controlled, allowing both the costs and benefits of inhibition to contribute, motor response inhibition has the opposite relationship with retrieval-induced forgetting. These findings underscore the importance of considering the correlated costs and benefits problem when studying individual differences in inhibitory control. More generally, they suggest that a shared inhibition mechanism may underlie people’s ability to control memories and actions.     

The role of response inhibition in temporal preparation: Evidence from a go/no-go task

During the foreperiod (FP) of a warned reaction task, participants engage in a process of temporal preparation to speed response to the impending target stimulus. Previous neurophysiological studies have shown that inhibition is applied during FP to prevent premature response. Previous behavioral studies have shown that the duration of FP on both the current and the preceding trial codetermine response time to the target. Integrating these findings, the present study tested the hypothesis that the behavioral effects find their origin in response inhibition on the preceding trial. In two experiments the variable-FP paradigm was combined with a go/no-go task, in which no-go stimuli required explicit response inhibition. The resulting data pattern revealed sequential effects of both FP (long or short) and response requirement (go or no-go), which could be jointly understood as expressions of response inhibition, consistent with the hypothesis.     

The study of inhibitory processes in aging with the Faust et al. paradigm (1997): methodological issues

Information provided by a word activates various potential meanings. Comprehension involves the suppression of inappropriate meanings of ambiguous words in order to finetune the intended meaning of sentences. If older adults become less efficient at inhibiting contextually irrelevant information, then multiple meanings of ambiguous words would be activated regardless of contextual bias. An alternative to multiple access was that older adults activate only the most dominant meaning of ambiguous words. According to this reservation, support for an inhibition deficit would require evidence that older adults activated the multiple meanings of ambiguous words. The effects of aging on both activation and inhibition of different meanings of ambiguous words were studied using Faust et al. (1997) paradigms. Results showed that both activation and inhibition response latency differed for the dominant and subordinate target and that the dominant meaning for one subject was not the same for another one. The implication of these results is that studies of inhibition should take dominance meaning of ambiguous word for each subject into account.     

提取诱发遗忘中的相关代价与效益问题：反应抑制能力与项目竞争强度的影响

采用提取练习范式,通过操作反应抑制能力和项目竞争强度两个变量,考察相关代价与效益问题（CCB）对大学生提取诱发遗忘（RIF）的影响。实验为2（反应抑制能力：高、低）×2（项目竞争强度：高、低）×3（项目类型：Rp+、Rp-、Nrp）三因素混合设计。结果发现,高反应抑制能力者在高项目竞争强度下产生了RIF,在低项目竞争强度下则未产生;低反应抑制能力者在高、低项目竞争强度下均未产生RIF。这些结果表明,对反应抑制能力正常的大学生而言,需要认知资源的抑制控制加工是RIF的产生机制,且这种抑制性RIF不受CCB的影响。     

Adaptive reasoning: Componential and eye movement analysis of geometric analogy performance

The present study explored individual differences in performance of a geometric analogies task. Whereas past studies employed true/false or two-alternative items, the present research included four-alternative items and studied eye movements and confidence judgements for each item performance as well as latency and error. Item difficulty proved to be a function of an interaction between the number of response alternatives and the number of elements in items, especially for subjects lower in fluid-analytic reasoning ability. Results were interpreted using two hypothesized performance strategies: constructive matching and response elimination. The less efficient of these, response elimination, seemed to be used more by lower ability subjects on more difficult items. While two previous theories resemble one or the other of these strategies, neither alone seems to capture the complexity of adaptive problem solving. It appears that a comprehensive theory should incorporate strategy shifting as a function of item difficulty and subject ability.Componential models, based in part on past research, revealed that a justification component was activated and deactivated depending upon the nature of the analogy being solved. In addition, two new components, spatial inference and spatial application, were identified as important on some items, suggesting that different geometric analogy items invoke different cognitive processing components. Thus, a comprehensive theory should also describe component activation and deactivation.     

The time course effect of moderate intensity exercise on response execution and response inhibition

This research aimed to investigate the time course effect of a moderate steady-state exercise session on response execution and response inhibition using a stop-task paradigm. Ten participants performed a stop-signal task whilst cycling at a carefully controlled workload intensity (40% of maximal aerobic power), immediately following exercise and 30 min after exercise cessation. Results showed that moderate exercise enhances a subjects’ ability to execute responses under time pressure (shorter Go reaction time, RT without a change in accuracy) but also enhances a subjects’ ability to withhold ongoing motor responses (shorter stop-signal RT). The present outcomes reveal that the beneficial effect of exercise is neither limited to motor response tasks, nor to cognitive tasks performed during exercise. Beneficial effects of exercise remain present on both response execution and response inhibition performance for up to 52 min after exercise cessation.     

Response inhibition in the parametric go/no-go task and its relation to impulsivity and subclinical psychopathy

The current study utilizes the parametric go/no-go task (PGNG), a task that examines changes in inhibitory performance as executive function load increases, to examine the link between psychopathic traits, impulsivity, and response inhibition in a cohort of healthy participants. The results show that as executive function load increased, inhibitory ability decreased. High scores on the Cognitive Complexity subscale of the Barratt Impulsivity Scale (BIS–11) predict poor inhibitory ability in the PGNG. Similarly, high scores on the Psychopathy Personality Inventory–Revised (PPI–R) Blame Externalization subscale predict response inhibition deficits in the PGNG, which loads more on the executive functions than the standard go/no-go task. The remaining BIS–11 as well as PPI–R subscales did not interact with inhibitory performance in the PGNG highlighting the specificity of associations between aspects of personality and impulsivity with inhibitory performance as cognitive load is increased. These data point towards the sensitivity of the PGNG in studying response inhibition in the context of highly impulsive populations and its utility as a measure of impulsivity.     

The efficacy of progressive relaxation in systematic desensitization and a proposal for an alternative competitive response--the relaxation response.

The theoretical basis of systematic desensitization is reciprocal inhibition in which an alternative, competitive response to anxiety is conditioned to arousal-producing, phobic stimuli. Abbreviated training in progressive relaxation is believed to serve as a competitive response to anxiety by decreasing autonomic nervous system activity. However, physiologic studies of progressive relaxation have not substantiated that its practice is associated with such decreased autonomic activity. Consequently, the use of progressive relaxation has been a confounding factor in the determination of the function of reciprocal inhibition in systematic desensitization. To confirm and refine the theoretical constructs of reciprocal inhibition, it is necessary to test the effects of a response which is competitive to the anxiety response. Such a response may be the relaxation response which is characterized by physiologic changes consistent with decreased autonomic nervous system activity. Derived from meditational practices, techniques which ehcit the relaxation response incorporate the element of focused attention which has been implicated as a critical factor in systematic desensitization. Thus, the use of the relaxation response should be a more appropriate method than progressive relaxation if the therapeutic usefulness of systematic desensitization is indeed due to reciprocal inhibition.