反应抑制的心理加工模型与神经机制

反应抑制是指抑制不符合当前需要的或不恰当行为反应的能力, 也是执行控制加工的重要成分。解释反应抑制的心理加工模型有两种: 反应与抑制相互独立的赛马模型和交互作用的赛马模型。近年来对反应抑制神经机制的研究表明: 额叶－基底神经节系统内的超直接通路和间接通路可能共同负责对优势反应的抑制, 而额下回、辅助运动区/辅助运动前区和前部扣带回皮层等脑区可能是抑制控制的关键脑区; 反应抑制与反应选择、工作记忆和注意的神经加工之间存在密切联系, 它们的激活脑区既相互重叠, 又相互区别; 右背外侧前额皮层的激活可能反映与抑制任务相关的注意和工作记忆的加工。未来的研究需要将脑损伤、神经功能成像和经颅磁刺激等多种技术结合起来, 进一步阐明上述脑区在反应抑制中的相互作用机制。     

反应抑制的训练:内容、效果与机制

近期的研究发现,个体的反应抑制能力具有一定的可塑性。研究者多采用双盲随机对照实验设计,训练的对象包括儿童、成人和特殊群体,研究者通过Go/Nogo、Stop-signal等任务进行为期1周至3周,45至7200试次不等的抑制控制能力训练,并结合行为、脑电以及脑成像等技术对训练效果进行评估,研究结果发现,接受了抑制控制训练的个体其抑制能力得到提升,并伴随脑神经活动的变化。另外,研究者发现,抑制控制能力的训练效果还可以迁移至个体日常生活中的表现。但是,也有些研究并未发现抑制控制训练的效果。训练任务的设置,评估任务的选择以及被试反应策略的差异等因素可能会影响训练的效果。抑制控制训练引发行为与大脑活动的变化可能是由于训练导致了个体建立了自上而下有意识的抑制控制模式和自下而上的自动抑制模式。反应抑制和冲突抑制可塑性的比较,儿童与老年人抑制功能的训练以及训练效果的追踪研究将成为该领域日后研究的重点问题。     

启动和重复抑制:启动神经机制的研究述评

启动是经验对当前任务的易化作用.重复抑制是刺激重复导致的皮层神经活动减少.大量研究表明启动与重复抑制密切相关.该文以理论假设对启动研究结果的解释效力为依据,对近期认知领域内有关启动和重复抑制的研究进行梳理,评介三种理论解释启动神经机制的适用性和局限性.指出未来研究可以考虑细化启动成分和重复抑制的具体关系,并尝试在此基础上建立神经元、重复抑制和行为启动的整合理论.这将对启动神经机制的理解具有重要意义.     

奖赏动机对自动反应抑制的影响

本研究把奖赏线索和目标导向的自动反应抑制范式相结合,来考察奖赏动机对自动反应抑制的影响。结果显示,基线阶段具有nogo颜色的侧翼字母会触发自动反应抑制,产生了反向兼容效应。奖赏阶段,奖赏条件下,go和nogo颜色的侧翼字母对反应时的影响不存在显著差异;非奖赏条件下,nogo颜色侧翼字母会产生更大的抑制效应,两种条件下nogo颜色的侧翼字母均没有引起反向兼容效应。结果表明：奖赏动机对自动反应抑制产生显著的影响,并且能够灵活地改变具有目标属性的侧翼字母的编码方式。     

无意识信息引发的认知控制及其神经机制

对无意识信息引发的认知控制的研究是揭示意识的功能与局限的重要方法和步骤.在无意识认知控制研究中主要采用模式掩蔽和偏对比掩蔽创设无意识条件,使用客观测量方法对意识状态进行测量.作者从无意识抑制控制、无意识冲突控制和无意识错误加工三个方面回顾了近年对无意识认知控制及其神经机制的研究.已有研究从行为和认知神经研究两个方面强有力地证明了无意识认知控制的存在,揭示了其神经机制.这些研究拓展了人们对意识信息广度和深度的认识,也为未来进一步揭示意识的起源等问题奠定了一定的基础.未来的研究可以从无意识认知控制和有意识认知控制的相互转化等方面进行进一步研究.     

绝对音高者对音乐的加工及其神经机制

绝对音高感是一种特殊的音高命名能力。通过论述绝对音高能力与音乐加工的关系,发现绝对音高者具有对音高、音程和旋律的加工优势,但他们对相对音高的加工存在劣势。同时,与非绝对音高者相比,绝对音高者大脑结构和功能都表现出特殊性。未来研究应进一步厘清音乐训练对绝对音高者音乐加工的影响。     

自我信息的反应抑制优势：来自神经振荡的证据

为探明个体对自我信息的反应抑制神经机制,记录了被试在完成面孔识别的停止信号任务时的脑电信号。神经振荡结果显示,反应任务中,加工自我面孔引发了更大的同步化δ节律和去同步化β节律;停止任务中,自我面孔引发了更大的去同步化β节律,特别在大脑前额区和中线上。表明,自我信息的反应抑制优势发生在抑制控制阶段,在于增强的β节律的去同步化促进了运动准备,提高了后续的动作抑制的速度。     

准备状态对反应抑制的影响

从事件因素和时间因素两个方面探讨了准备状态对反应抑制的影响。事件准备可降低反应模式的不确定性 ,而时间准备则与降低反应时间的不确定性有关。线索、反应概率以及刺激呈现时间等因素不仅导致反应时间出现变化 ,还可引起反应力、心跳间期以及LRP和CNV等脑电指标发生变化。传统的反应抑制研究以反应时为指标 ,不能揭示反应抑制的内部过程 ,而心理生理学方法能弥补这一缺陷。生理指标与行为指标的结合 ,以及生理指标之间的结合 ,可更有效地探讨准备状态对反应抑制的效应。     

决策信心的认知机制与神经基础

决策信心是指在进行判断或决策时, 个体对其决策最优性或正确性的信心程度。决策信心的单过程理论认为决策与信心评估是并行的同一加工过程; 而决策后理论认为决策和信心评估是串行的两个加工过程。决策信心存在两种典型的偏差效应：过分自信和信心不足。决策信心的神经机制研究指出, 信心评估可能是决策过程中最基本并且普遍存在的一个成分; 对决策信心评估敏感的脑区包括扣带回、背外侧前额叶和顶上小叶等。未来研究应该在决策信心产生的机制、信心与决策如何交互的心理及神经机制等领域展开大量研究。     

面孔认知及其神经机制的独特性

面孔识别与物体识别都是人类社会生活中的重要功能,但两者之问是否有着相同的脑机制呢?是否采用两个分离的认知系统呢?发展心理学家、心理生理学家和神经心理学家对此有着不同的看法。Farah提出了三个衡量面孔识别与物体识别差异的标准：①脑定位标准：参与面孔识别与物体识别的脑结构与脑机制不同;②加工系统标准：即每个系统独立运作而不依靠另外一个系统;③信息处理方式标准：两个系统按照不同的方式来处理信息。本文就此三条标准结合近年来心理学、神经科学和神经心理学的研究来阐明面孔识别与物体识别的差异。     

The effect of methylphenidate on three forms of response inhibition in boys with AD/HD

The current study was aimed at (a) investigating the effect of three doses methylphenidate (MPH) and placebo on inhibition of a prepotent response, inhibition of an ongoing response, and interference control in Attention Deficit/Hyperactivity Disorder (AD/HD), and (b) studying dose-response relations for the three forms of response inhibition. To meet these aims, the following tasks were selected: two versions of the Stop Paradigm for inhibition of a prepotent response, a Circle Tracing Task and a recently developed Follow Task for inhibition of an ongoing response, and the Stroop Color-Word Test and an Eriksen Flanker Task for interference control. These tasks were administered to 23 boys with AD/HD during four treatment conditions: 5 mg MPH, 10 mg MPH, 20 mg MPH, and placebo. A pseudorandomized, multiple-blind, placebo-controlled, within-subject design was used. As hypothesized, inhibitory control in children with AD/HD improved under MPH compared to placebo. However, this effect was only significant for inhibition of a prepotent response and inhibition of an ongoing response (as measured by the Follow Task), but not for interference control. The relation between treatment condition and response was linear. However, this linear relation was due to improved inhibitory control under MPH compared to placebo, because no effects of MPH dose were observed for any of the response inhibition measures.     

The influence of overlapping response sets on task inhibition

The aim of the present study was to examine the contribution of overlapping response sets to the occurrence of task inhibition, measured as n-2 task repetition cost. We had subjects switch among four tasks. Three tasks overlapped on both stimulus set and response set. A fourth, neutral, univalent task never overlapped on the stimulus set but, across three experiments, varied in terms of the degree of overlap in the response set. We found that overlap in response set affects task inhibition. We suggest that response set overlap increases the competition among tasks and, thus, triggers task inhibition to resolve this competition.     

The time course effect of moderate intensity exercise on response execution and response inhibition

This research aimed to investigate the time course effect of a moderate steady-state exercise session on response execution and response inhibition using a stop-task paradigm. Ten participants performed a stop-signal task whilst cycling at a carefully controlled workload intensity (40% of maximal aerobic power), immediately following exercise and 30 min after exercise cessation. Results showed that moderate exercise enhances a subjects’ ability to execute responses under time pressure (shorter Go reaction time, RT without a change in accuracy) but also enhances a subjects’ ability to withhold ongoing motor responses (shorter stop-signal RT). The present outcomes reveal that the beneficial effect of exercise is neither limited to motor response tasks, nor to cognitive tasks performed during exercise. Beneficial effects of exercise remain present on both response execution and response inhibition performance for up to 52 min after exercise cessation.     

A general latent trait model for response processes

The purpose of the current paper is to propose a general multicomponent latent trait model (GLTM) for response processes. The proposed model combines the linear logistic latent trait (LLTM) with the multicomponent latent trait model (MLTM). As with both LLTM and MLTM, the general multicomponent latent trait model can be used to (1) test hypotheses about the theoretical variables that underlie response difficulty and (2) estimate parameters that describe test items by basic substantive properties. However, GLTM contains both component outcomes and complexity factors in a single model and may be applied to data that neither LLTM nor MLTM can handle. Joint maximum likelihood estimators are presented for the parameters of GLTM and an application to cognitive test items is described.This research was partially supported by the National Institute of Education grant number NIE-6-7-0156 to Susan Embretson (Whitely), principal investigator. However the optinions expressed herein do not necessarily reflect the position or policy of the National Institute of Education, and no official endorsement by the National Institute of Education should be inferred.     

Effects of stimulus-stimulus compatibility and stimulus-response compatibility on response inhibition

Previous studies demonstrated that interference control in stimulus–stimulus compatibility tasks slowed down stopping in the stop signal task (e.g., Kramer, A. F., Humphrey, D. G., Larish, J. F., Logan, G. D., & Strayer, D. L. (1994). Aging and inhibition: beyond a unitary view of inhibitory processing in attention. psychology and aging, 9, 491–512). In the present study, the impact of stimulus–stimulus compatibility and stimulus–response compatibility on response inhibition is further investigated. In Experiment 1, the stop signal task was combined with a traditional horizontal Simon task and with a vertical variant. For both dimensions, stopping responses was prolonged in incompatible trials, but only when the previous trial was compatible. In Experiment 2, the Simon task was combined with a spatial Stroop task in order to compare the effects of stimulus–stimulus and stimulus–response compatibility. The results demonstrated that both types of compatibility influenced stopping in a similar way. These findings are in favor of the hypothesis that response inhibition in the stop signal task and interference control in conflict tasks rely on similar mechanisms.     

The effect of information distribution on collaborative inhibition

Two experiments examined collaborative memory for information that was studied by all group members (shared items) and information that was studied by only a subset of group members (unshared items). In both experiments significant collaborative inhibition (reduced output of the collaborative groups relative to the pooled output of individuals) was obtained for both shared and unshared information. In Experiment 1 the magnitude of collaborative inhibition was larger for unshared items than for shared items, possibly because unshared items were less likely to be acknowledged and thus incorporated into the groups’ recall. In Experiment 2 the magnitude of collaborative inhibition for shared and unshared information was equivalent once all participants were provided with the category name associated with the shared and unshared items. The results of the experiments are discussed in relation to the retrieval strategy disruption hypothesis of collaborative inhibition and the role of social process variables, such as acknowledgement, in influencing collaborative inhibition across situations involving memory of shared and unshared information.     

Search asymmetry, sustained attention, and response inhibition

In the present experiment, we used search asymmetry to test whether the sustained attention to response task is a better measure of response inhibition or sustained attention. Participants performed feature present and feature absent target detection tasks using either a sustained attention to response task (SART; high Go low No-Go) or a traditionally formatted task (TFT; high No-Go low Go) response format. In addition to performance, we employed functional near infrared spectroscopy (fNIRS) to measure lateral cerebral oxygenation levels and self-reports of Tense Arousal, Energetic Arousal, task related and unrelated thoughts occurring during the tasks. Detections were lower and reaction times longer in the feature absent search than the feature present search regardless of response format. Detections were lower, but reaction times shorter in the SART than the TFT regardless of feature search. Greater right than left frontal hemisphere activation occurred in the SART than the TFT. In addition, the SART was more fatiguing based on self-reports than the TFT, but there were no differences in Task-Unrelated Thoughts across task conditions. Overall, the results suggest the SART places high response inhibition, not necessarily sustained attention, demands on participants.     

Reliability and plasticity of response inhibition and interference control

This study investigated the internal reliability, temporal stability and plasticity of commonly used measures of inhibition-related functions. Stop-signal, go/no-go, antisaccade, Simon, Eriksen flanker, Stroop and Continuous Performance tasks were administered twice to 23 healthy participants over a period of approximately 11 weeks in order to assess test–retest correlations, internal consistency (Cronbach’s alpha), and systematic between as well as within session performance changes. Most of the inhibition-related measures showed good test–retest reliabilities and internal consistencies, with the exception of the stop-signal reaction time measure, which showed poor reliability. Generally no systematic performance changes were observed across the two assessments with the exception of four variables of the Eriksen flanker, Simon and Stroop task which showed reduced variability of reaction time and an improvement in the response time for incongruent trials at second assessment. Predominantly stable performance within one test session was shown for most measures. Overall, these results are informative for studies with designs requiring temporally stable parameters e.g. genetic or longitudinal treatment studies.     

The "sense of agency" and its underlying cognitive and neural mechanisms

The sense of agency is a central aspect of human self-consciousness and refers to the experience of oneself as the agent of one’s own actions. Several different cognitive theories on the sense of agency have been proposed implying divergent empirical approaches and results, especially with respect to neural correlates. A multifactorial and multilevel model of the sense of agency may provide the most constructive framework for integrating divergent theories and findings, meeting the complex nature of this intriguing phenomenon.     

Age of acquisition: its neural and computational mechanisms

The acquisition of new skills over a life span is a remarkable human ability. This ability, however, is constrained by age of acquisition (AoA); that is, the age at which learning occurs significantly affects the outcome. This is most clearly reflected in domains such as language, music, and athletics. This article provides a perspective on the neural and computational mechanisms underlying AoA in language acquisition. The authors show how AoA modulates both monolingual lexical processing and bilingual language acquisition. They consider the conditions under which syntactic processing and semantic processing may be differentially sensitive to AoA effects in second-language acquisition. The authors conclude that AoA effects are pervasive and that the neural and computational mechanisms underlying learning and sensorimotor integration provide a general account of these effects.