睡眠剥夺对大鼠短时记忆和记忆保持的影响

本实验应用小站台水环境方法剥夺REM(快速眼动相)睡眠。观察到REM睡眠剥夺对大鼠跳台回避反应短时记忆的影响,其影响程度随睡眠剥夺时间的延长而加大;同时观察到睡眠剥夺也影响大鼠跳台回避反应记忆的保持。但在本实验条件下,未见到睡眠剥夺对大鼠学习该模式的能力有影响。作者对上述实验结果进行了讨论。     

睡眠剥夺时大鼠电休克阈值的变化

我们在研究睡眠剥夺影响大鼠记忆巩固的实验中,观察到睡眠剥夺引起大鼠条件反射的反应时(R T_(CR))明显缩短。我们认为,这可能反映了动物在睡眠剥夺后脑的兴奋性有所升高,本实验用电休克阈值作指标验证这一看法。     

一夜睡眠剥夺对大学生短时记忆的影响

我们研究了一夜睡眠剥夺对大学生短时记忆的影响。我们在动物身上也进行了初步实验。研究结果表明:睡眠剥夺对于动物的短时记忆也可能有不利影响,其跳台模式短时记忆受损程度的大小与睡眠剥夺时间的长短有关系。本研究比较了一夜睡眠剥夺对于青年人五项分测验短时记忆的影响,其目的是为探讨睡眠与记忆的关系提供参考资料。     

雏鸡左眼视剥夺不同时程后记忆形成过程与脑内Jun样蛋白表达差异的研究

本实验采用一次性味觉厌恶回避学习,研究２日龄雏鸡左眼视剥夺２４小时后的记忆形成过程,并与左眼视剥夺２小时后的记忆形成过程进行比较,同时利用免疫组化技术,观察并比较单眼视剥夺不同时程及单眼学习后Ｊｕｎ样蛋白在雏鸡脑内不同区域（ＨＶ和ＬＰＯ）的表达。结果表明：１．视剥夺左眼２４小时后对雏鸡的短时记忆、中时记忆和长时记忆均无明显影响,但中时记忆保持水平略低于双眼学习条件下的中时记忆保持水平。这与视剥夺２     

睡眠剥夺影响恐惧情绪加工的认知神经机制

睡眠剥夺与恐惧情绪加工的各个过程息息相关。睡眠剥夺损害了恐惧的习得过程, 而且影响着杏仁核、内侧前额叶的活动及它们之间的功能连接; 睡眠剥夺削弱了恐惧记忆的巩固和再巩固过程, 不仅破坏了恐惧记忆再巩固过程相关蛋白质和酶的合成, 同时也影响着海马、杏仁核、内侧前额叶的活动以及它们之间的功能连接; 睡眠剥夺损害了恐惧的消退, 同时也改变了海马、杏仁核等相关脑区的活动模式。未来的研究应从睡眠剥夺影响恐惧情绪加工的认知神经机制、睡眠剥夺与恐惧情绪相关障碍的关系等角度展开, 力图深入理解睡眠剥夺影响恐惧情绪加工的认知神经机制。     

单眼视剥夺2小时对雏鸡记忆保持的影响

以2日龄雏鸡为研究对象,采用一次性被动回避学习模型,以不透明胶纸封贴一侧眼的方法,研究2日龄雏鸡单侧眼视剥夺2小时后对视觉学习记忆的影响,并与双眼学习条件下的记忆情况进行比较;试图探讨雏鸡在视觉信息加工过程中左、右半球的作用。实验结果表明：剥夺一侧眼（无论左或右）2小时后对雏鸡的短时记忆无影响,明显干扰雏鸡的中期和长时记忆,特别是剥夺左眼干扰更明显。     

荷苞牡丹碱对雏鸡单眼视剥夺后记忆形成过程的改善作用

了雏鸡左眼视剥夺２小时后,进行一次性被动回避学习的记忆形成过程;以及ｒ一氨基丁酸（ｒ－ａｍｉｎｏ－ｂｕｔｙｒｉｃａｃｉｄＧＡＢＡ）的受体颉颌颃剂荷苞牡丹碱（ｂｉｃｕｃｕｌｌｉｎｅＢｉｃ）,对雏鸡左眼视剥夺后记忆形成过程的改善作用。实验结果表明：１．雏鸡左眼视剥夺２小时后,仅能形成较好的短时记忆,中时记忆和长时记忆难以形成;２．训练前１０分钟颅内注射荷苞牡丹碱,对雏鸡左眼视剥夺２小时后的记忆缺失有明显的改善作用,形成了较好的中时记忆和长时记忆。     

睡眠对恐惧学习的影响及其认知神经机制

睡眠问题可能会诱发恐惧相关情绪障碍(焦虑、创伤性应激障碍、恐怖症等),研究睡眠影响恐惧学习的认知神经机制,有助于增强对恐惧相关情绪障碍的预测、诊断和治疗。以往研究表明睡眠剥夺影响恐惧习得和消退主要是通过抑制vmPFC活动,阻碍其与杏仁核的功能连接,从而导致恐惧习得增强或是消退学习受损。进一步研究发现睡眠不同阶段对恐惧学习相关脑区有独特的影响:剥夺(缺乏)快速眼动睡眠会抑制vmPFC活动、增强杏仁核、海马激活,导致恐惧习得增强,消退学习受损,此外边缘皮层的功能连接减少破坏了记忆巩固(恐惧记忆和消退记忆);而慢波睡眠主要与海马变化有关,慢波睡眠期间进行目标记忆重激活可促进恐惧消退学习。未来研究需要增加睡眠影响恐惧泛化的神经机制研究、及昼夜节律中断对恐惧消退的影响,以及关注动物睡眠研究向人类睡眠研究转化中存在的问题。     

倒班与正常班医护人员记忆特点的比较

20—35岁倒班和正常班医护人员400名经问卷调查睡眠情况之后,对其中88名受试者给予记忆测验。测验材料为“临床记忆量表”,包括指向记忆、联想学习、图象自由回忆、无意义图形再认和人像特点联系回忆五项分测验。研究结果表明:倒班医护人员在值夜班期间睡眠质量受到明显影响,在上正常白班期间睡眠质量虽有所改善,但仍不及正常班医护人员;倒班组和正常班组各项记忆测验成绩均无显著性差异,但两组记忆特点有些不同。     

眼睛运动如何与记忆相关？

很久以来,人们一直在致力于研究人的眼动与心理活动之间的关系,从而揭示其间的奥妙。众多研究表明,睡眠时的快速眼动（RapidEyeMovements,REM）及其周期对记忆的形成与巩固有重要作用。在清醒状态下,人的眼动就是为了获得视觉信息,如果涉及记忆任务,这就是编码阶段的具体行动。另外,问题解决过程也有眼动参与。总体看来,眼动和记忆之间是一种双向的关系,适当的眼动训练或许能够提高记忆成绩。     

PATTERNS OF EXPERIENCE AND THE ACQUISITION OF CONSERVATION OF LENGTH

The effects of five procedures on the acquisition of conservation of length were studied. A Müller-Lyer illusion was used to induce apparent changes in length in the test- and practice-situations. Two procedures involved practice on addition-subtraction, one a progressive increase in the strength of the Müller-Lyer illusion, and one the anticipation of the outcome of displacements of the objects. A fifth procedure was a composite of the other four. The results showed some acquisitions in all groups, with highest frequency in the anticipation group, and lowest in the increase-in-illusion group.     

不同年龄广告名人效应的心理加工机制研究

本研究从自动化加工和控制性加工这个视角研究了名人效应的心理加工机制。实验运用加工分离程序,探讨了不同年龄阶段的受众对名人广告的信息加工模式。结果发现：(1)名人效应是一个普遍存在的现象,与用一般消费者做代言人相比,青少年、成年人(大学生)以及老年人对名人广告均明显存在更多的自动化加工,且加工水平没有年龄差异。但是,老年人的控制性加工明显低于其他两组;(2)在非注意条件下,代言人的专业化程度明显地影响了大学生组的控制性加工,但与各组被试的自动化加工都关系不大。这些研究发现为广告策略的制定带来了一些新的启示。     

JUDGMENTS OF SEXISM: A COMPARISON OF THE SUBTLETY OF SEXISM MEASURES AND SOURCES OF VARIABILITY IN JUDGMENTS OF SEXISM

We compared the subtlety of four measures of sexism and sources of variation in male and female psychology students' judgments that beliefs from these scales and everyday behaviors were sexist. Participants judged traditional gender role and hostile sexist beliefs as more sexist than benevolent and modern sexist beliefs, indicating the latter were more subtle measures of sexism. Participants also judged traditional gender role behaviors as more sexist than unwanted sexual attention, suggesting the latter may less readily be identified as sexist. Variation in judgments of beliefs as sexist was related to differences in likelihood of endorsing such beliefs. This relation fully accounted for the tendency for men to be less likely to judge beliefs as sexist in comparison to women. Endorsement of Modern and Hostile Sexist beliefs was related to judgments of behaviors as sexist. The implications of the results for scale usage and identifying sexist behavior are discussed.     

ON THE EFFECTS OF NONCONTINGENT DELIVERY OF DIFFERING MAGNITUDES OF REINFORCEMENT

We conducted a parametric analysis of response suppression associated with different magnitudes of noncontingent reinforcement (NCR). Participants were 5 adults with severe or profound mental retardation who engaged in a manual response that was reinforced on variable-ratio schedules during baseline. Participants were then exposed to NCR via multielement and reversal designs. The fixed-time schedules were kept constant while the magnitude of the reinforcing stimulus was varied across three levels (low, medium, and high). Results showed that high-magnitude NCR schedules produced large and consistent reductions in response rates, medium-magnitude schedules produced less consistent and smaller reductions, and low-magnitude schedules produced little or no effect on responding. These results suggest that (a) NCR affects responding by altering an establishing operation (i.e., attenuating a deprivation state) rather than through extinction, and (b) magnitude of reinforcement is an important variable in determining the effectiveness of NCR.     

SOME NORMATIVE IMPLICATIONS OF KORSGAARD'S THEORY OF THE INTERSUBJECTIVITY OF REASON

Abstract: This article argues that Christine Korsgaard's conception of self‐constitution can be historicized by considering the impact of actual humans on our reflective activity. Because Korsgaard bases her argument on a philosophy of action rather than of intention (as Kant does), and our actions must always be concrete, the article argues that the principles for action which we develop in reflection are likewise responses to concrete human demands. It further interprets the types of demands humans make on each other as the expression of historical circumstance rather than as transcendentally anchored. The notion of universal respect that reflection seeks to achieve is thus seen as developing by a self‐correcting process of concrete human interaction. Finally, the article concludes that there can be no metaphysical proof of morality, since morality develops through human interaction that seeks to approximate the idea of respect for persons.     

大学生自尊发展的特点

采用自编《大学生自尊评定问卷》,探讨1104名大学生自尊发展的特点。结果表明：（1）随着年级的增长大学生自尊呈稳定发展趋势,重要感、胜任感、归属感三个维度上表现出显著的年级差异。（2）大学生自尊发展存在着显著的性别差异,男生发展水平显著高于女生,性别差异主要体现在归属感维度。（3）文科生外表感维度得分显著高于理科生,独生子女、城市学生以及学生干部在自尊总分及其三个维度得分显著高于非独生子女、农村学生以及非学生干部。