Reading and controlling human brain activation using real-time functional magnetic resonance imaging

Understanding how to control how the brain's functioning mediates mental experience and the brain's processing to alter cognition or disease are central projects of cognitive and neural science. The advent of real-time functional magnetic resonance imaging (rtfMRI) now makes it possible to observe the biology of one's own brain while thinking, feeling and acting. Recent evidence suggests that people can learn to control brain activation in localized regions, with corresponding changes in their mental operations, by observing information from their brain while inside an MRI scanner. For example, subjects can learn to deliberately control activation in brain regions involved in pain processing with corresponding changes in experienced pain. This may provide a novel, non-invasive means of observing and controlling brain function, potentially altering cognitive processes or disease.     

Types of creativity

Psychonomic Bulletin & Review - Imagine the impact if we were to understand, and thus could reliably enhance, something – anything – about how creativity works in the brain. The...     

The neurobiology of virtual reality pain attenuation.

During the past decade, virtual reality (VR) has gained recognition as a means of attenuating pain during medical procedures. However, while investigators have examined the effects of virtual environments on level of distraction, subjective pain intensity, and brain activity, there have been only a handful of investigations into the neurobiological mechanisms associated with VR's efficacy. In an effort to explain how VR may alter pain perception and produce analgesia, as well as to guide the development of novel and improved VR pain treatments, this review aims to link the wealth of empirical data examining the neurobiology of pain to the growing field of VR. This review is separated into three main sections: (a) a brief overview of the current literature on the use of VR for the treatment of pain; (b) a review of the basic neurobiology of how pain is detected, processed, and controlled by the brain; and (c) an exploration into how current VR pain treatments may impact the pain system to produce analgesia. In addition, the future of VR for pain treatment is discussed, including how current treatments might be improved and novel ways to use VR to treat pain might be developed. Speculation on future VR interventions is based on our current understanding of how the brain processes pain and how VR appears to alter this process and produce analgesia.     

The Christianization of African Traditional Religions

In studies of the historical growth and spread of Christianity in Africa, the focus has been too much on Christianizing African social and religious institutions and structures, and not enough on African traditional religion itself, which needs to be addressed by Christianity. This article addresses the core – that is, the theology and worldview – of the African traditional religion. It argues that this core needs to be Christianized and shows how this can be done. In order to achieve this task, the article uses a new theological method, a “systematic theology” of African traditional religion, as the basis for a theological method of engagement and interaction of religions and worldview. This new method explains in practical terms how Christianity can effectively Christianize African traditional religions and worldviews.     

Love Your Neighbour as Yourself

This paper examines the many ways interreligious dialogue and interreligious relationship-building interact with and serve how we live out – with others – the moral core of the Christian faith, which is the love of God and neighbour. I take as an example the contemporary Poor People’s Campaign in the United States. The campaign originated with the Rev. Dr Martin Luther King Jr, the Rev. Ralph Abernathy, and others involved in the civil rights movements of the early 1960s. While the Poor People’s Campaign was initiated by and is led by Christians, it is intentionally inclusive of people of many different faiths and those with no particular faith, all of whom share the commitment to love and to serve the poor.     

Universal stories: How narratives satisfy core motives

Abstract

For millennia, narratives have been a primary mode of oral discourse. Narrative presentation of information has been shown to facilitate interpersonal and group communication. However, research indicates that narratives are more than merely an adaptive mode of communication. Narrative is a fundamental – and perhaps foundational – element of social and cultural life. The present article posits that the centrality of narrative in social life is due to narrative’s ability to help satisfy the five core social motives, as identified by Fiske belonging, understanding, control, self-enhancement, and trust. In so doing, this article reviews empirical and theoretical work examining basic narrative processes, autobiographical narratives, and entertainment narrative consumption to illustrate how narrative thought helps to satisfies core human motives and in turn, how the narrative construction process informs self and identity formation.     

Emotion and Pain: A Functional Cerebral Systems Integration

Emotion and pain are psychological constructs that have received extensive attention in neuropsychological research. However, neuropsychological models of emotional processing have made more progress in describing how brain regions interact to process emotion. Theories of emotional processing can describe inter-hemispheric and intra-hemispheric interactions during emotional processing. Due to similarities between emotion and pain, it is thought that emotional models can be applied to pain. The following review examines the neuropsychology of emotion and pain using a functional cerebral systems approach. Specific comparisons are made between pain and anger. Attention is given to differences in cerebral function and physiology that may contribute to the processing of emotion and pain. Suggestions for future research in emotion and pain are given.     

阅读障碍儿童的形音捆绑缺陷及其脑神经机制

形音捆绑缺陷研究是国内外阅读障碍研究领域的一个新方向。本文阐述了形音捆绑加工的理论与定义,综述了国内外研究者经常采用的三种形音捆绑的研究范式:配对联想学习、变化检测范式和线索回忆任务,介绍并分析了各研究范式的优缺点、适用范围及主要研究发现。同时,综述与评价了国内外有关阅读障碍形音捆绑缺陷的脑机制研究的主要结论及不足。最后,本文讨论了现有研究在实验设计和理论上的贡献与不足,提出了今后的研究方向和改进建议。     

Belongingness as a core personality trait: how social exclusion influences social functioning and personality expression

People have a fundamental need for positive and lasting relationships. This need to belong is rooted in evolutionary history and gave rise to the development of traits that enable individuals to gain acceptance and to avoid rejection. Because belongingness is a core component of human functioning, social exclusion should influence many cognitive, emotional, and behavioral outcomes and personality expression. This article summarizes recent evidence that social exclusion causes an assortment of outcomes, many of which depend on whether the excluded can gain acceptance or forestall possible distress. It highlights common overlap in physical and social pain systems and how a physical painkiller can reduce the pain of social exclusion. Finally, it shows how social exclusion moderates the effects of traits on cognition, emotion, and behavior. To appreciate personality processes in social contexts, scientists should consider how people respond to social exclusion and how the need to belong influences personality expression.     

Metaphysics of Pain; Semantics of ‘Pain’

Functionalism is often used to identify mental states with physical states. A particularly powerful case is Lewis's analytical functionalism. Kripke's view seriously challenges any such identification. The dispute between Kripke and Lewis's views boils down to whether the term ‘pain’ is rigid or nonrigid. It is a strong intuition of ours that if it feels like pain it is pain, and vice versa, so that ‘pain’ should designate, with respect to every possible world, all and only states felt as pain. Hence, in order to settle the dispute, we need to check which of the two – Kripke's use of ‘pain’ as rigid, or Lewis's use of ‘pain’ as nonrigid – better meets this intuition. I show that, despite crucial differences in both their semantic and metaphysical assumptions, surprisingly, both views meet this intuition equally well. Thus it appears that this question of rigidity cannot, in principle, be solved, and so, at least with respect to this particular dispute, the jury is still out on whether mental states are identical to physical states. 1     

Beyond sympathy: Smith’s rejection of Hume’s moral theory

Adam Smith’s Theory of Moral Sentiments (TMS) has long been recognized as importantly influenced by, and in part responding to, David Hume’s earlier ethical theory. With regard to Smith’s account of the foundations of morals in particular, recent scholarly attention has focused on Smith’s differences with Hume over the question of sympathy. Whilst this is certainly important, disagreement over sympathy in fact represents only the starting point of Smith’s engagement with – and eventual attempted rejection of – Hume’s core moral theory. We can see this by recognizing the TMS’s account of moral foundations as predicated upon a rejection of Hume’s distinction between the natural and artificial virtues. Smith is in turn revealed as generating a major break with Hume – a break which, if based on a superior theory of moral foundations (as Smith thought it to be) has important consequences for how we treat Smith and Hume in both the history of philosophy and contemporary moral theory.     

新生儿语音感知的神经基础:元分析

语言习得能力是人类在进化中获得的重要能力之一。语言认知的核心功能是语音加工, 因此, 语音加工的脑机制是认知心理学研究的重要课题。我们采用元分析方法, 对使用近红外技术考察新生儿语音感知的结构检测、偏差检测和母语感知的研究进行系统的定量分析, 探究新生儿的典型语音感知脑机制以及这三类语音加工相关脑区的异同。结果显示, 左侧额下回是新生儿检测语音结构的关键脑区; 双侧颞叶在新生儿语音偏差刺激检测中发挥关键作用; 新生儿的母语语音加工存在左侧化优势。     

Pleasures of the brain

How does the brain cause positive affective reactions to sensory pleasure? An answer to pleasure causation requires knowing not only which brain systems are activated by pleasant stimuli, but also which systems actually cause their positive affective properties. This paper focuses on brain causation of behavioral positive affective reactions to pleasant sensations, such as sweet tastes. Its goal is to understand how brain systems generate 'liking,' the core process that underlies sensory pleasure and causes positive affective reactions. Evidence suggests activity in a subcortical network involving portions of the nucleus accumbens shell, ventral pallidum, and brainstem causes 'liking' and positive affective reactions to sweet tastes. Lesions of ventral pallidum also impair normal sensory pleasure. Recent findings regarding this subcortical network's causation of core 'liking' reactions help clarify how the essence of a pleasure gloss gets added to mere sensation. The same subcortical 'liking' network, via connection to brain systems involved in explicit cognitive representations, may also in turn cause conscious experiences of sensory pleasure.     

Development and the epigenome: the ‘synapse’ of gene–environment interplay

This paper argues that there is a revolution afoot in the developmental science of gene–environment interplay. We summarize, for an audience of developmental researchers and clinicians, how epigenetic processes – chromatin structural modifications that regulate gene expression without changing DNA sequences – may offer a strong, parsimonious account for the convergence of genetic and contextual variation in the genesis of adaptive and maladaptive development. Epigenetic processes may play a plausible explanatory role in understanding: divergent trajectories and sexual dimorphisms in brain development; statistical interactions between genes and environments; the biological embedding of early psychosocial adversities; the linkages of such adversities to disorders of mental health; the striking individual variation in the strength of those linkages; the molecular origins of critical and sensitive periods; and the transgenerational inheritance of risk and protection. Taken together, these arguments converge in a claim that epigenetic processes constitute a promising and illuminating point of connection – a ‘synapse’ – between genes and environments.     

Distinction between mental pain and psychic suffering as separate entities in the patient's experience

Abstract

Mental pain and psychic suffering are herein defined as two separate concepts in psychoanalysis. The concept of mental pain lies at the core of psychoanalysis; it was introduced by Freud and was further elaborated by a number of investigators, mostly by Bion. Mental pain refers to a pain that the patient reports as being impossible to describe in words, and lacking any associations, whereas psychic suffering can be both named and described by the patient. Mental pain is derived from non-tolerance on the part of the psychic apparatus when it is harmed by very painful emotions. In contrast to psychic suffering, mental pain resists elaboration and transformation by dream-work. How to address and transform the patient's mental pain is a major challenge facing the analyst in his clinical work because mental pain may halt or slow the progression of the analytical process. To overcome this hindrance, the work of the analyst is focused on helping patients to modify their mental pain into psychic suffering, that is, to reactivate in the patient the chain of transformations that generates thought. The analyst is also challanged with the mental pain of the patients because he has himself to tolerate the mental patient induced by counter transference. Suggestions for the analyst on how to deal with the mental pain of the patient during psychoanalytic therapy are proposed.     

The role of prediction in mental processing: A process approach

Although prediction plays a prominent role in mental processing, we have only limited understanding of how the brain generates and employs predictions. This paper develops a theoretical framework in three steps. First I propose a process model that describes how predictions are produced and are linked to behavior. Subsequently I describe a generative mechanism, consisting of the selective amplification of neural dynamics in the context of boundary conditions. I hypothesize that this mechanism is active as a process engine in every mental process, and that therefore each mental process proceeds in two stages: (i) the formation of process boundary conditions; (ii) the bringing about of the process function by the operation – within the boundary conditions – of a relatively ‘blind’ generative process. Thirdly, from this hypothesis I derive a strategy for describing processes formally. The result is a multilevel framework that may also be useful for studying mental processes in general.     

Materialism and ‘the soft substance of the brain’: Diderot and plasticity

ABSTRACT

Materialism is the view that everything that is real is material or is the product of material processes. It tends to take either a ‘cosmological’ form, as a claim about the ultimate nature of the world, or a more specific ‘psychological’ form, detailing how mental processes are brain processes. I focus on the second, psychological or cerebral form of materialism. In the mid-to-late eighteenth century, the French materialist philosopher Denis Diderot was one of the first to notice that any self-respecting materialist had to address the question of the status and functional role of the brain, and its relation to our mental life. After this the topic grew stale, with knee-jerk reiterations of ‘psychophysical identity’ in the nineteenth-century, and equally rigid assertions of anti-materialism. In 1960s philosophy of mind, brain–mind materialism reemerged as ‘identity theory’, focusing on the identity between mental processes and cerebral processes. In contrast, Diderot’s cerebral materialism allows for a more culturally sedimented sense of the brain, which he described in his late Elements of Physiology as a ‘book – except it is a book which reads itself’. Diderot thus provides a lesson for materialism as it reflects on the status of the brain, science and culture.     

The Buddha was a devoted nationalist: Buddhist nationalism,ressentiment, and defending Buddhism in Myanmar

Since 2012, Buddhist nationalist movements – especially the 969 movement and Ma Ba Tha – have emerged in Burma/Myanmar seeking to defend Buddhism against mainly the Muslim minority, with monks delivering nationalist anti-Muslim sermons to huge audiences. The aim of this article is to demonstrate how a discriminatory nationalist agenda can – by appealing to the common trope of Buddhism-in-danger – appear to be justified to Buddhists. Based mainly on nationalist sermons, as well as on fieldwork and nationalist publications, this article examines discourse on the Buddha as a nationalist. First, it argues that Burmese Buddhist nationalism, analytically, should be understood as a ressentiment ideological discourse that also informs a Buddhist-nationalist discipline claimed to bring karmic merit. Second, it traces the roots of this ideology to the colonial period. Third, the article outlines and seeks to define how ‘Buddhist nationalism’ should be understood in an emic sense.     

Conditions of Cognitive Sanity and the Internalist Credo

BonJour has proposed background conditions on internalist justification, which Kornblith argues are inconsistent with a core internalist ‘credo’ – that subjects internally alike are justificationally alike – signaling the ‘death’ of internalism. The funeral arrangements are premature, though more systematic consideration of background conditions is needed. The majority of BonJour's conditions are not background conditions as their failure makes an epistemically relevant internal difference. This neutralizes Kornblith's criticisms and reveals how the proposed conditions are not departures from internalism. BonJour's background conditions are simply conditions, the credo remains intact, and Kornblith's objections do not spell problems for internalism, let alone death.     

On The Content and Character of Pain Experience

Tracking representationalism explains the negative affective character of pain, and its capacity to motivate action, by reference to the representation of the badness for us of bodily damage. I argue that there is a more fitting instantiation of the tracking relation – the badness for us of extremely intense stimuli – and use this to motivate a non‐reductive approach to the negative affective character of pain. The view of pain proposed here is supported by consideration of three related topics: the pain caused when the body is damaged, reparative pain and the messenger‐shooting objection to tracking representationalism.