从认知神经的角度看内隐记忆和外显记忆的分离

当前的一些理论观点认为,内隐记忆和外显记忆依赖于两种不同的记忆系统,它们与大脑的不同区域相联系。该文通过回顾以往相关研究,从神经心理学及神经成像两方面对两种记忆系统的分离现象进行概述：在神经心理学领域发现的证据表明内隐记忆在神经解剖上与外显记忆是分离的;使用fMRI和PET技术,研究者观察到与内隐记忆有关的枕颞区及左下前额区中衰减的神经活动,以及与外显记忆有关的内侧颞区、前额皮层和后内侧顶皮层中增强的活动;使用ERP技术,研究也发现了两种记忆神经系统在时空上的不同特征     

A developmental trajectory in implicit memory is revealed by picture fragment completion

Dissociations between performance on implicit and explicit tasks have often been taken as evidence that different neural structures subserve the two types of memory. One such dissociation involves developmental differences that emerge in explicit tasks, but which appear to be absent in implicit tasks. Such findings are consistent with the idea that implicit memory is subserved by a more primitive system that evolves earlier at both phylogenetic and ontogenetic levels. The present paper reviews previous studies that claimed to find evidence that implicit memory is fully developed in very young children. Issues of measurement error, ceiling effects, and insufficient power brought up questions about those studies with respect to the developmental issue. The present study compares performance on implicit (picture fragment completion) and explicit (free recall and recognition) memory tasks with groups ranging in age from 5-28 years. We find a reliable developmental trend in both implicit and explicit performance in which the former cannot be attributed to the operation of explicit memory processes. Thus, we conclude that implicit memory, like explicit memory, develops with age.     

A Developmental Trajectory in Implicit Memory is Revealed by Picture Fragment Completion

Dissociations between performance on implicit and explicit tasks have often been taken as evidence that different neural structures subserve the two types of memory. One such dissociation involves developmental differences that emerge in explicit tasks, but which appear to be absent in implicit tasks. Such findings are consistent with the idea that implicit memory is subserved by a more primitive system that evolves earlier at both phylogenetic and ontogenetic levels. The present paper reviews previous studies that claimed to find evidence that implicit memory is fully developed in very young children. Issues of measurement error, ceiling effects, and insufficient power brought up questions about those studies with respect to the developmental issue. The present study compares performance on implicit (picture fragment completion) and explicit (free recall and recognition) memory tasks with groups ranging in age from 5–28 years. We find a reliable developmental trend in both implicit and explicit performance in which the former cannot be attributed to the operation ofexplicit memory processes. Thus, we conclude that implicit memory, like explicit memory, develops with age.     

A comparison of working memory skills and learning in children with developmental coordination disorder and moderate learning difficulties

The present study compared 6–11 years old with developmental coordination disorder (DCD) and those with moderate learning difficulties (MLD) on measures of memory (verbal short‐term and working memory, visuo‐spatial short‐term and working memory), literacy and numeracy, and IQ. The findings indicate that children with DCD appear to be impaired in all four areas of memory function; in particular they performed at significantly lower levels than children with MLD in measures of verbal short‐term memory, visuo‐spatial short‐term and working memory. In contrast, performance of children with MLD in the memory measures was within age‐expected levels, with deficits observed only in verbal working memory tasks. There were also differential links between memory and attainment between the two groups, and these were significant even after statistically accounting for the contribution of IQ. Reasons for why working memory contributes to learning in these two developmental groups are discussed. Copyright © 2006 John Wiley & Sons, Ltd.     

Decreased parahippocampal activity in associative priming: evidence from an event-related fMRI study

In recent years, there has been intense debate on the neural basis of associative priming, particularly on the role of the medial temporal lobe (MTL) in retrieving associative information without awareness. In this study, event-related fMRI was used while healthy subjects performed a perceptual identification task on briefly presented unrelated word pairs and an associative recognition memory task. Contamination of priming by explicit memory was successfully controlled, as associative priming and explicit memory were dissociated on the behavioral level. The fMRI results showed a functional dissociation within the MTL with respect to associative priming effects. The right parahippocampal cortex, but not the hippocampus, showed decreased activation for old vs. new pairs and old vs. recombined pairs (associative priming). The bilateral hippocampus and the right parahippocampal cortex were involved in explicit associative memory. These data provide evidence that subregions of the MTL participate in associative priming even when explicit involvement was controlled. Thus, different regions within the MTL play distinct roles in explicit and implicit associative memory.     

Just lying there,remembering: Improving recall of prose in amnesic patients with mild cognitive impairment by minimising interference

The hallmark of amnesia is poor explicit long‐term memory along with normal short‐term memory. It is often stated that information encountered by amnesic patients is forgotten within 1 minute of presentation. However, previous work has not distinguished between forgetting as a function of time versus the interfering material occupying that time. We show that there is a marked benefit of reduced interference in amnesic patients with mild cognitive impairment (MCI), a condition that is characterised by anterograde amnesia in the absence of other neuropsychological deficits and carries an increased risk for Alzheimer's disease. The result suggests that long‐term memory is encoded in these patients to a greater extent than had been realised but that their memory is highly vulnerable to interference.     

Implicit and explicit measures of prejudice and stereotyping: do they assess the same underlying knowledge structure?

Do implicit and explicit measures of ethnic attitudes assess the same underlying knowledge structure in long term memory? This study uses both a correlational and an experimental design (N = 133) in order to address this central question. In the first part, we suggest that self‐presentational strategies can partly explain why the relation between implicit and explicit measures is inconsistent in the existing literature. More specifically, we show that when there are strong norms against prejudice, implicit and explicit measures are significantly negatively related. In the second part, an experimental manipulation of relative gratification (RG), the opposite of relative deprivation, reveals that when the level of explicit prejudice increases (RG condition), a similar effect is also observed at the implicit level. Together, these results suggest that implicit and explicit measures assess similar knowledge structure. Copyright © 2004 John Wiley & Sons, Ltd.     

Working memory moderates the effect of the integrative process of implicit and explicit autonomous motivation on academic achievement

In previous research, autonomous motivation (AM) has been found to be associated with school achievement, but the relation has been largely heterogeneous across studies. AM has typically been assessed with explicit measures such as self‐report questionnaires. Recent self‐determination theory (SDT) research has suggested that converging implicit and explicit measures can be taken to characterize the integrative process in SDT. Drawing from dual‐process theories, we contended that explicit AM is likely to promote school achievement when it is part of an integrated cognitive system that combines easily accessible mental representations (i.e., implicit AM) and efficient executive functioning. A sample of 272 university students completed a questionnaire and a lexical decision task to assess their explicit and implicit AM, respectively, and they also completed working memory capacity measures. Grades were obtained at the end of the semester to examine the short‐term prospective effect of implicit and explicit AM, working memory, and their interaction. Results of moderation analyses have provided support for a synergistic interaction in which the association between explicit AM and academic achievement was positive and significant only for individuals with high level of implicit AM. Moreover, working memory was moderating the synergistic effect of explicit and implicit AM. Explicit AM was positively associated with academic achievement for students with average‐to‐high levels of working memory capacity, but only if their motivation operated synergistically with high implicit AM. The integrative process thus seems to hold better proprieties for achievement than the sole effect of explicit AM. Implications for SDT are outlined.     

The reciprocal relation between sleep and memory in infancy: Memory‐dependent adjustment of sleep spindles and spindle‐dependent improvement of memories

Sleep spindle activity in infants supports their formation of generalized memories during sleep, indicating that specific sleep processes affect the consolidation of memories early in life. Characteristics of sleep spindles depend on the infant's developmental state and are known to be associated with trait‐like factors such as intelligence. It is, however, largely unknown which state‐like factors affect sleep spindles in infancy. By varying infants’ wake experience in a within‐subject design, here we provide evidence for a learning‐ and memory‐dependent modulation of infant spindle activity. In a lexical‐semantic learning session before a nap, 14‐ to 16‐month‐old infants were exposed to unknown words as labels for exemplars of unknown object categories. In a memory test on the next day, generalization to novel category exemplars was tested. In a nonlearning control session preceding a nap on another day, the same infants heard known words as labels for exemplars of already known categories. Central–parietal fast sleep spindles increased after the encoding of unknown object–word pairings compared to known pairings, evidencing that an infant's spindle activity varies depending on its prior knowledge for newly encoded information. Correlations suggest that enhanced spindle activity was particularly triggered, when similar unknown pairings were not generalized immediately during encoding. The spindle increase triggered by previously not generalized object–word pairings, moreover, boosted the formation of generalized memories for these pairings. Overall, the results provide first evidence for a fine‐tuned regulation of infant sleep quality according to current consolidation requirements, which improves the infant long‐term memory for new experiences.     

How is phonological processing related to individual differences in children’s arithmetic skills?

While there is evidence for an association between the development of reading and arithmetic, the precise locus of this relationship remains to be determined. Findings from cognitive neuroscience research that point to shared neural correlates for phonological processing and arithmetic as well as recent behavioral evidence led to the present hypothesis that there exists a highly specific association between phonological awareness and single‐digit arithmetic with relatively small problem sizes. The present study examined this association in 37 typically developing fourth and fifth grade children. Regression analyses revealed that phonological awareness was specifically and uniquely related to arithmetic problems with a small but not large problem size. Further analysis indicated that problems with a high probability of being solved by retrieval, but not those typically associated with procedural problem‐solving strategies, are correlated with phonological awareness. The specific association between phonological awareness and arithmetic problems with a small problem size and those for which a retrieval strategy is most common was maintained even after controlling for general reading ability and phonological short‐term memory. The present findings indicate that the quality of children’s long‐term phonological representations mediates individual differences in single‐digit arithmetic, suggesting that more distinct long‐term phonological representations are related to more efficient arithmetic fact retrieval.     

Implicit and explicit memory performance in children with attention deficit/hyperactivity disorder

The present investigation examined implicit and explicit memory in 20 children diagnosed with attention deficit/hyperactivity disorder (AD/HD) and 20 matched controls. Consistent with previous research, children with AD/HD performed more poorly than controls on an explicit test of long‐term memory for pictures. New results were that (a) there was no deficit on an implicit memory test for equivalent material and that (b) the observed deficit in explicit memory operated over and above any effects of depression/anxiety. Another finding to emerge was that AD/HD children had greater difficulty than controls in identifying pictures of objects that were presented in an unusual form, either rotated or degraded. Overall, the pattern of results is interpreted in terms of deficient effortful/resource‐intensive processes in AD/HD but intact automatic processes.     

Phonological short‐term memory and vocabulary development: further evidence on the nature of the relationship

The nature and generality of the developmental association between phonological short‐term memory and vocabulary knowledge was explored in two studies. Study 1 investigated whether the link between vocabulary and verbal memory arises from the requirement to articulate memory items at recall or from earlier processes involved in the encoding and storage of the verbal material. Four‐year‐old children were tested on immediate memory measures which required either spoken recall (nonword repetition and digit span) or recognition of a sequence of nonwords. The phonological memory–vocabulary association was found to be as strong for the serial recognition as recall‐based measures, favouring the view that it is phonological short‐term memory capacity rather than speech output skills which constrain word learning. In Study 2, the association between phonological memory skills and vocabulary knowledge was found to be strong in teenaged as well as younger children, indicating that phonological memory constraints on word learning remain significant throughout childhood. Copyright © 1999 John Wiley & Sons, Ltd.     

Phoneme‐Order Encoding During Spoken Word Recognition: A Priming Investigation

In three experiments, we examined priming effects where primes were formed by transposing the first and last phoneme of tri‐phonemic target words (e.g., /byt/ as a prime for /tyb/). Auditory lexical decisions were found not to be sensitive to this transposed‐phoneme priming manipulation in long‐term priming (Experiment 1), with primes and targets presented in two separated blocks of stimuli and with unrelated primes used as control condition (/mul/‐/tyb/), while a long‐term repetition priming effect was observed (/tyb/‐/tyb/). However, a clear transposed‐phoneme priming effect was found in two short‐term priming experiments (Experiments 2 and 3), with primes and targets presented in close temporal succession. The transposed‐phoneme priming effect was found when unrelated prime‐target pairs (/mul/‐/tyb/) were used as control and more important when prime‐target pairs sharing the medial vowel (/pys/‐/tyb/) served as control condition, thus indicating that the effect is not due to vocalic overlap. Finally, in Experiment 3, a transposed‐phoneme priming effect was found when primes sharing the medial vowel plus one consonant in an incorrect position with the targets (/byl/‐/tyb/) served as control condition, and this condition did not differ significantly from the vowel‐only condition. Altogether, these results provide further evidence for a role for position‐independent phonemes in spoken word recognition, such that a phoneme at a given position in a word also provides evidence for the presence of words that contain that phoneme at a different position.     

Dissociations between implicit and explicit memory in children: the role of strategic processing and the knowledge base

A review of the literature shows that explicit memory develops substantially from three years of age to adulthood, while implicit memory remains stable across this age range. Previously, this developmental dissociation has been attributed to different memory systems, or to confounds with perceptual vs. conceptual processing. Prompted by an alternative developmental framework, the experiments reported here provide evidence against both interpretations. Instead, it will be argued that (a) the implicit-explicit developmental dissociation reflects differences in strategic processing (strategy use and metamemory) across childhood and (b) that implicit memory can show development if a child's knowledge base in the tested domain is developing with age.     

The origins of word learning: Brain responses of 3‐month‐olds indicate their rapid association of objects and words

The present study explored the origins of word learning in early infancy. Using event‐related potentials (ERP) we monitored the brain activity of 3‐month‐old infants when they were repeatedly exposed to several initially novel words paired consistently with each the same initially novel objects or inconsistently with different objects. Our results provide strong evidence that these young infants extract statistic regularities in the distribution of the co‐occurrences of objects and words extremely quickly. The data suggest that this ability is based on the rapid formation of associations between the neural representations of objects and words, but that the new associations are not retained in long‐term memory until the next day. The type of brain response moreover indicates that, unlike in older infants, in 3‐month‐olds a semantic processing stage is not involved. Their ability to combine words with meaningful information is caused by a primary learning mechanism that enables the formation of proto‐words and acts as a precursor for the acquisition of genuine words.     

Effects of working memory load on long‐term word priming

Three experiments assessed the role of verbal and visuo‐spatial working memory in supporting long‐term repetition priming for written words. In Experiment 1, two priming tasks (word stem completion and category‐exemplar production) were included with three levels of load on working memory: (1) without memory load, (2) memory load that involved storing a string of six digits, and (3) memory load that involved storing a graphic shape. Experiments 2 and 3 compared the effects of a verbal (Experiment 2) or a visual (Experiment 3) working memory load at encoding on both an implicit (word stem completion) and an explicit test (cued recall). The results show no effect of memory load in any of the implicit memory tests, suggesting that priming does not rely on working memory resources. By contrast, loading working memory at encoding causes a significant disruptive effect on the explicit memory test for words when the load is verbal but not visual.     

Very long‐term recall and recognition of well‐learned material

Three experiments examined very long‐term verbatim memory (from 4 months to 28 years) for lengthy, complex material. Experiments 1 and 2 found that recall (12 and 20 months after the material was last accessed) was at or near ceiling for many participants, and was significantly higher than free‐choice recognition, with recognition failure for recallable words (RF) being observed. The magnitude of the effect corresponded to that predicted by the Tulving–Wiseman ( 1975 ) function. Experiment 3 found that recall was at or near ceiling for 3 years, then declined dramatically as the retention interval increased. However, given equal amounts of context as retrieval cues, forced‐choice recognition remained relatively strong for as long as 28 years. These findings provide evidence of long‐term memory for exact details of complex discourse far in excess of previous demonstrations, and, under certain circumstances, extend the RF phenomenon to lengthy, well‐learned texts over long retention intervals. Copyright © 2002 John Wiley & Sons, Ltd.     

Listening comprehension in preschoolers: The role of memory

The current study analyzed the relationship between text comprehension and memory skills in preschoolers. We were interested in verifying the hypothesis that memory is a specific contributor to listening comprehension in preschool children after controlling for verbal abilities. We were also interested in analyzing the developmental path of the relationship between memory skills and listening comprehension in the age range considered. Forty‐four, 4‐year‐olds (mean age = 4 years and 6 months, SD =4 months) and 40, 5‐year‐olds (mean age = 5 years and 4 months, SD =5 months) participated in the study. The children were administered measures to evaluate listening comprehension ability (story comprehension), short‐term and working memory skills (forward and backward word span), verbal intelligence and receptive vocabulary. Results showed that both short‐term and working memory predicted unique and independent variance in listening comprehension after controlling for verbal abilities, with working memory explaining additional variance over and above short‐term memory. The predictive power of memory skills was stable in the age range considered. Results also confirm a strong relation between verbal abilities and listening comprehension in 4‐ and 5‐year‐old children.     

Differences in brain morphology and working memory capacity across childhood

Working memory (WM) skills are closely associated with learning progress in key areas such as reading and mathematics across childhood. As yet, however, little is known about how the brain systems underpinning WM develop over this critical developmental period. The current study investigated whether and how structural brain correlates of components of the working memory system change over development. Verbal and visuospatial short‐term and working memory were assessed in 153 children between 5.58 and 15.92 years, and latent components of the working memory system were derived. Fractional anisotropy and cortical thickness maps were derived from T1‐weighted and diffusion‐weighted MRI and processed using eigenanatomy decomposition. There was a greater involvement of the corpus callosum and posterior temporal white matter in younger children for performance associated with the executive part of the working memory system. For older children, this was more closely linked with the thickness of the occipitotemporal cortex. These findings suggest that increasing specialization leads to shifts in the contribution of neural substrates over childhood, moving from an early dependence on a distributed system supported by long‐range connections to later reliance on specialized local circuitry. Our findings demonstrate that despite the component factor structure being stable across childhood, the underlying brain systems supporting working memory change. Taking the age of the child into account, and not just their overall score, is likely to be critical for understanding the nature of the limitations on their working memory capacity.     

Neural correlates of conceptual implicit memory and their contamination of putative neural correlates of explicit memory

During episodic recognition tests, meaningful stimuli such as words can engender both conscious retrieval (explicit memory) and facilitated access to meaning that is distinct from the awareness of remembering (conceptual implicit memory). Neuroimaging investigations of one type of memory are frequently subject to the confounding influence of the other type of memory, thus posing a serious impediment to theoretical advances in this area. We used minimalist visual shapes (squiggles) to attempt to overcome this problem. Subjective ratings of squiggle meaningfulness varied idiosyncratically, and behavioral indications of conceptual implicit memory were evident only for stimuli given higher ratings. These effects did not result from perceptual-based fluency or from explicit remembering. Distinct event-related brain potentials were associated with conceptual implicit memory and with explicit memory by virtue of contrasts based on meaningfulness ratings and memory judgments, respectively. Frontal potentials from 300 to 500 msec after the onset of repeated squiggles varied systematically with perceived meaningfulness. Explicit memory was held constant in this contrast, so these potentials were taken as neural correlates of conceptual implicit memory. Such potentials can contaminate putative neural correlates of explicit memory, in that they are frequently attributed to the expression of explicit memory known as familiarity. These findings provide the first neural dissociation of these two memory phenomena during recognition testing and underscore the necessity of taking both types of memory into account in order to obtain valid neural correlates of specific memory functions.