Mood induced cognitive and emotional reactivity, life stress, and the prediction of depressive relapse

This study examined a group of participants who were fully remitted from a previous episode of major depressive disorder, and evaluated the role of cognitive and emotional reactivity to a mood challenge, and life stress in the prediction of relapse. Fifty-two participants were evaluated during remission, and their reactivity (i.e., change in dysfunctional attitudes and emotional state) to a depressed mood induction was evaluated. The cohort was followed up 12 months after the initial assessment. Thirty-five percent of the sample experienced a relapse during the follow-up period. Relapse was predicted by higher rates of life stress, and lower levels of emotional reactivity (specifically less reduction in happiness) to the mood induction during the initial assessment. Cognitive reactivity to the mood induction did not predict relapse, nor did the interaction between cognitive reactivity and life stress. These findings are discussed in terms of recent literature suggesting that depression is associated with insensitivity to emotion context, such that depressed individuals display blunted emotional responses to affective stimuli, including sadness-inducing stimuli. These findings suggest that insensitivity to emotional context may also be a characteristic of euthymic individuals at risk of relapse.     

Perceptual negativity predicts greater reactivity to negative events in daily life

Reinforcement sensitivity theory includes the idea that people differ in their sensitivity to negative events, but relevant process-based assessments have not been developed. The present studies assessed sensitivity to negative events in terms of the extent to which negative word stimuli were perceived to be larger than neutral word stimuli. There was a general tendency to overestimate the size of negative relative to neutral words, but individuals differed substantially in this form of what is termed perceptual negativity. Of more importance, two studies (total N = 151) found systematic relationships between individual differences in perceptual negativity and reactivity to negative events in daily diary protocols. Study 1 found that within-person variations in the occurrence of daily negative events undermined goal-related optimism to a greater extent at higher, relative to lower, levels of perceptual negativity. Study 2 conceptually replicated this interaction in the context of within-person associations between the occurrence of daily negative events and antisocial behavior. These findings are important in advancing reinforcement sensitivity theory, in operationalizing a particular component of it, and in extending it to reactivity processes in daily life.     

Sleep quality in healthy and mood-disordered persons predicts daily life emotional reactivity

Disordered sleep has been linked to impaired emotional functioning in healthy and depressed individuals. Little is known, however, about how chronic sleep problems influence emotional reactivity in everyday life. Participants with major or minor unipolar depressive disorder (n?=?60) and healthy controls (n?=?35) reported on sleep and emotional responses to daily life events using a computerised Experience Sampling Method. We examined whether impaired sleep quality influenced emotional reactivity to daily events, and if this relationship was altered by unipolar mood disorders. Among healthy individuals, sleep difficulties were associated with enhanced negative affect (NA) to unpleasant events and a dulled response to neutral events. However, among mood-disordered persons, sleep difficulties were associated with higher NA across all types of everyday life events. Impaired sleep quality differentially affects daily life emotional reactions as a function of depression.     

Mood trajectories following daily life events

Little is known about the magnitude and duration of mood responses to daily negative events as a function of gender, history of mood disorder, and current substance use. Using computerized ambulatory monitoring techniques, perceived negativity of minor daily events and state affect were prospectively examined every 3 h on average for a 7-day period. Event negativity was associated with depressed mood for 6–9 h following event occurrence, and was associated with happy mood for 3–6 h. Gender and substance use moderated the relationship between event negativity and mood states concurrently, and remained influential for approximately 3 h following the event. History of mood disorder did not moderate any within- or across-day relationships between event negativity and mood. No evidence was found for mood uplifts following daily events in either within- or across-day analyses. The findings are discussed relative to assessment timing in investigations of vulnerability-stress theories.     

Change in emotional processing during a dialectical behavior therapy-based skills group for major depressive disorder

Across studies, paying attention to and analyzing one's emotions has been found to be both positively and negatively correlated with depression symptoms. One way of reconciling these seemingly contradictory findings is the possibility that attending to emotions in a skillful manner may help to reduce depression whereas attending to emotions with limited skill may be counterproductive. Dialectical behavior therapy (DBT) is a clinical intervention designed to foster adaptive awareness, expression, regulation, tolerance, and acceptance of emotions. Results of the present report come from a pilot study of a 16-week DBT-based skills training group for treatment-resistant major depressive disorder (MDD) as an adjunctive treatment to pharmacotherapy. Patients were randomized to treatment or a waitlist control group. A significant interaction revealed that increases in emotional processing were associated with decreases in depression symptoms in the DBT-based skills group; however, increases in emotional processing in the waitlist condition were associated with increases in depression. Results offer preliminary support for the idea that participating in DBT-based skills training may help individuals with treatment-resistant MDD to develop skills that facilitate processing emotions in a way that helps to reduce rather than exacerbate depression symptoms.     

Influence of dysphoria on positive and negative cognitive reactivity to daily mood fluctuations

We used an experience sampling design to investigate the influence of dysphoria on positive and negative cognitive reactivity. Participants recorded their thoughts and mood four times per day on PDA devices for one week. We hypothesized that those higher in dysphoria would demonstrate a greater increase in negative thinking in response to negative mood, and a weaker increase in positive cognitions in response to positive mood. These hypotheses were largely supported. For those participants who reported higher initial dysphoria, there was a stronger association between negative mood and thinking and a weaker link between positive mood and thinking. Regression analyses indicated that positive and negative cognitive reactivity were independently related to dysphoria, suggesting that they represent distinct processes. Our results highlight the importance of understanding levels of both negative and positive cognitive reactivity and underscore the benefits of assessing mood and cognition with repeated measurements in "real-time," in order to better understand the antecedent effects of mood on thinking.     

Effects of daily events on mood states in major depressive disorder

Major depressive disorder (MDD) is characterized by high negative affect (NA) and low positive affect (PA), but little is known about emotional reactivity in daily life. The authors used experience sampling methodology to investigate changes in NA and PA following minor daily events in MDD compared with healthy participants. Contrary to expectation, MDD participants did not report more frequent negative events, although they did report fewer positive events. Multilevel regression showed that both NA and PA responses to negative events were blunted in the MDD group, whereas responses to positive events were enhanced. NA responses to negative events persisted longer in MDD participants. Depressed participants with a positive family history or longer current episodes showed relatively greater NA responses to negative events.     

Skin conductance responses as predictor of emotional responses to stressful life events

Preferential preattentive processing towards threat has been proposed to play a casual role in the development of anxiety, mainly because it reliably predicts emotional responding to stressful events. However, in the investigation of the predictive value of preferential preattentive processing towards threat, the emotional Stroop task has exclusively being used. This study was designed to prospectively investigate the predictive value of skin conductance reactivity in response to masked (i.e., preattentively perceived) threatening pictures on emotional responding following stressful life events. To collect skin conductance data, the picture perception task was administered to 136 police recruits due to enroll into active duty within 2-4 months. To assess psychological distress following emotionally stressful life events, the impact of event scale were administered approximately 24 months later. Controlling for trait anxiety, analyses indicated that enhanced skin conductance reactivity in response to masked threatening pictures (relative to neutrals) was a strong predictor of emotional responding to stressful life events. This finding support preferential preattentive processing towards threat as a relatively independent factor predictive of emotional responding.     

Emotional intelligence and psychological resilience to negative life events

This study investigated the relative importance of six emotional intelligence (EI) dimensions in the prediction of psychological resilience to multiple negative life events. The strength of relations between life events and distress varied markedly across three latent classes of participants, reflecting vulnerable, average and resilient profiles. Discriminant function analysis indicated that class membership varied as a function of four EI dimensions, with higher scores predicting membership to the resilient class. Across the 414 participants, Emotional Self-Awareness, Emotional Expression, Emotional Self-Control and particularly Emotional Self-Management appeared central to psychological resilience in the aftermath of multiple negative life events.     

Emotional reactivity to daily events in major and minor depression

Although emotional dysfunction is an important aspect of major depressive disorder (MDD), it has rarely been studied in daily life. Peeters, Nicolson, Berkhof, Delespaul, and deVries (2003) observed a surprising mood-brightening effect when individuals with MDD reported greater reactivity to positive events. To better understand this phenomenon, we conducted a multimethod assessment of emotional reactivity to daily life events, obtaining detailed reports of appraisals and event characteristics using the experience-sampling method and the Day Reconstruction Method (Kahneman, Krueger, Schkade, Schwarz, & Stone, 2004) in 35 individuals currently experiencing a major depressive episode, 26 in a minor depressive (mD) episode, and 38 never-depressed healthy controls. Relative to healthy controls, both mood-disordered groups reported greater daily negative affect and lower positive affect and reported events as less pleasant, more unpleasant, and more stressful. Importantly, MDD and mD individuals reported greater reductions in negative affect following positive events, an effect that converged across assessment methods and was not explained by differences in prevailing affect, event appraisals, or medications. Implications of this curious mood-brightening effect are discussed.     

Mindful attention predicts greater recovery from negative emotions,but not reduced reactivity

This study investigated the role of dispositional mindful attention in immediate reactivity to, and subsequent recovery from, laboratory-induced negative emotion. One hundred and fourteen undergraduates viewed blocks of negative pictures followed by neutral pictures. Participants’ emotional responses to negative pictures and subsequent neutral pictures were assessed via self-reported ratings. Participants’ emotional response to negative pictures was used to index level of emotional reactivity to unpleasant stimuli; emotional response to neutral pictures presented immediately after the negative pictures was used to index level of emotional recovery from pre-induced negative emotion (residual negativity). Results indicated that mindful attention was not associated with the emotional response to negative pictures, but it was associated with reduced negative emotion in response to the neutral pictures presented immediately after the negative pictures, suggesting better recovery as opposed to reduced reactivity. This effect was especially pronounced in later experimental blocks when the accumulation of negative stimuli produced greater negative emotion from which participants had to recover. The current study extends previous findings on the relationship between dispositional mindfulness and reduced negative emotion by demonstrating that mindful attention may facilitate better recovery from negative emotion, possibly through more effective disengagement from previous stimuli.     

Examination of emotional Stroop interference in obsessive-compulsive disorder

Previous research has produced conflicting findings on whether or not patients with subclinical or manifest obsessive-compulsive disorder (OCD) share an attentional bias for anxiety-related material. In the present study, 35 OCD patients were compared with 20 healthy controls on their performance in an emotional Stroop paradigm. Nine different stimulus conditions were compiled, including sets for depression-related and anxiety-related words as well as stimuli from two constructs with a potential relevance for the pathogenesis and maintenance of OCD symptomatology: responsibility and conscientiousness. Patients did not show enhanced interference for any of the conditions. Syndrome subtype and severity, avoidance and speed of information processing did not moderate results. The present study concurs with most prior research that OCD patients display no interference effect for general threat words. It deserves further consideration, that emotional interference effects in OCD as seen in other anxiety disorders occur when using idiosyncratic word material with a direct relation to the individual's primary concerns.     

Comparing emotional reactivity and regulation in infants born ELGA and VLGA

Emotional reactivity and regulation behaviors were compared in infants born extremely low gestational age (ELGA) and very low gestational age (VLGA) during the still-face procedure. Infants born ELGA demonstrated greater emotional reactivity and displayed less frequent gaze avoidance, more frequent gestures, and more self-comforting behaviors.     

Ruminative self-focus, negative life events, and negative affect

Ruminative thinking is believed to exacerbate the psychological distress that follows stressful life events. An experience-sampling study was conducted in which participants recorded negative life events, ruminative self-focus, and negative affect eight times daily over one week. Occasions when participants reported a negative event were marked by higher levels of negative affect. Additionally, negative events were prospectively associated with higher levels of negative affect at the next sampling occasion, and this relationship was partially mediated by momentary ruminative self-focus. Depressive symptoms were associated with more frequent negative events, but not with increased reactivity to negative events. Trait rumination was associated with reports of more severe negative events and increased reactivity to negative events. These results suggest that the extent to which a person engages in ruminative self-focus after everyday stressors is an important determinant of the degree of distress experienced after such events. Further, dispositional measures of rumination predict mood reactivity to everyday stressors in a non-clinical sample.     

Let it be: Accepting negative emotional experiences predicts decreased negative affect and depressive symptoms

The present studies examined whether a tendency to accept negative emotional experiences buffers individuals from experiencing elevated negative affect during negative emotional situations (Study 1) and from developing depressive symptoms in the face of life stress (Study 2). Both studies examined female samples. This research expands on existing acceptance research in four ways. First, it examined whether acceptance has beneficial correlates when it matters most: in emotionally taxing (versus more neutral) contexts. Second, in Study 2 a prospective design was used in which acceptance was measured before stress was encountered and before outcomes were measured. Third, depressive symptoms (rather than general functioning or trauma symptoms) were examined as a particularly relevant outcome in the context of stress. Fourth, to enhance generalizability, a community sample (versus undergraduates or a purely clinical sample) was recruited. Results indicated that acceptance was correlated with decreased negative affect during a negative emotion induction but not an affectively neutral condition (Study 1). In Study 2, acceptance interacted with life stress such that acceptance predicted lower levels of depressive symptoms after higher, but not lower, life stress. These results suggest that accepting negative experiences may protect individuals from experiencing negative affect and from developing depressive symptoms.     

Screening detoxifying inpatients with substance-related disorders for a major depressive disorder

The Beck Depression Inventory-Fast Screen for Medical Settings (BDI-FS; [Beck, Steer, & Brown, 2000]) and the Mood Module (MM) from the Primary Care Evaluation of Mental Disorders [Spitzer, Williams, Kroenke, Linzer, deGruy, III, Hahn, & Brody, 1995] were used to screen 100 inpatients detoxifying from alcohol, illicit substances, or both for a major depressive disorder (MDD). Receiver operating characteristic (ROC) analyses indicated that both tests were highly and comparably effective in differentiating patients who were and not diagnosed with a MDD; the ROC areas-under-curves for the BDI-FS and MM were, respectively, .87 and .84. A BDI-FS cut-off score of 10 and above had 90% sensitivity and 78% specificity rates, and a MM cut-off score of 7 and above had 90% sensitivity and 72% specificity rates for discriminating patients with and without a MDD. The clinical advantages and disadvantages of both instruments for rapidly screening detoxifying inpatients for clinical depression were discussed.     

Reinforcement sensitivity theory predicts positive and negative affect in daily life

Laboratory studies of Reinforcement Sensitivity Theory have associated sensitivity to punishment (SP) with negative affect and sensitivity to reward (SR) with positive affect. However, few studies have examined the expression of these systems and their response to cues of reward in daily life. The current study employed experience sampling methodology (ESM) to assess the association of SP and SR with affect and perceptions of situations in daily life. SP was positively associated with negative affect and negatively associated with positive affect in daily life, whereas SR was associated with positive affect and one aspect of negative affect, irritability/anger. Furthermore, high SP participants experienced smaller increases in positive affect and smaller decreases in negative affect in some situations that were perceived as positive, in comparison to low SP participants. In contrast, high SR participants experienced greater decreases in negative affect in some situations that were perceived as positive, in comparison to low SR participants.     

Mood reactivity to daily negative events in early adolescence: relationship to risk for psychopathology

Emotional responses to negative daily experiences in young adolescents may provide important clues to the development of psychopathology, but research is lacking. This study assessed momentary mood reactivity to daily events as a function of risk profile in a school sample, ages 11-14. High-risk (HR, n=25) and low-risk (LR, n=106) subgroups completed frequent self-reports of mood and events for 5 days. HR adolescents reported more negative events involving family and peers. Multilevel modeling results showed that negative events, especially if stressful, were associated with increased negative and decreased positive affects, with heightened responses in HR adolescents. HR adolescents with greater stress over the last 3 months showed additional increases in depressed mood following negative events. Altered reactivity to and dysfunctional appraisals of daily events may link adolescent risk profiles to later mental health problems.     

Child abuse and negative explicit and automatic self-associations: The cognitive scars of emotional maltreatment

Individuals reporting Childhood Abuse (CA) (i.e., emotional neglect, emotional-, physical- and sexual-abuse) are marked by increased explicit (i.e. self-reported) negative self-associations, and an increased risk to develop depression or anxiety disorders. Automatic self-associations might play an important role in the development and maintenance of affective disorders after exposure to CA, since automatic associations are assumed to be involved in uncontrolled (spontaneous) affective behavior. This study examined whether individuals reporting a history of CA show stronger automatic (and explicit) self-depression and/or self-anxiety associations than individuals who report no CA in a large cohort study (Netherlands Study of Depression and Anxiety (NESDA), n = 2981). The Implicit Association Test (IAT) was utilized to assess automatic self-depression and self-anxiety associations. We found that CA was associated with enhanced automatic (and explicit) self-depression and self-anxiety associations. Additionally, when compared to physical- and sexual-abuse, Childhood Emotional Maltreatment (CEM; emotional abuse and emotional neglect) had the strongest link with enhanced automatic (and explicit) self-depression and self-anxiety associations. In addition, automatic and explicit negative self-associations partially mediated the association between CEM and depressive or anxious symptomatology. Implications regarding the importance of CA, and CEM in particular will be discussed.     

Obsessive-compulsive disorder and the five-factor model of personality: distinction and overlap with major depressive disorder

Research on individual differences in obsessive-compulsive disorder (OCD) has focused largely on analogue models with participants experiencing sub-clinical obsessions and/or compulsions. Few studies have examined the association between normal, dimensional personality traits and obsessive-compulsive symptomatology in a clinical sample. The purpose of this study was to examine personality differences in patients with a primary diagnosis of OCD (n = 98) or major depression (n = 98) using the domains and facets of the five-factor model of personality (FFM). Patients completed the self-report version of the Revised NEO Personality Inventory (NEO PI-R). When contrasted with community controls (Revised NEO Personality Inventory (NEO-PI-R) and NEO Five-Factor Inventory (NEO-FFI) professional manual, Psychological Assessment Resources, Odessa, FL, 1992), participants with OCD were found to differ across the domains (and facets) of neuroticism, extraversion, and conscientiousness and the facets of openness and agreeableness. Further, when compared to depressed participants, those with OCD were found to be more extraverted, agreeable, conscientious and less neurotic. With the exception of the conscientiousness domain (and facets), these significant differences were maintained even after controlling for depression severity. These results highlight the unique associations between trait domains and facets of the FFM and OCD.