Associations of cardiorespiratory fitness and moderate-to-vigorous physical activity with latent cognitive abilities in older adults

It has been demonstrated that physical activity has a small but positive effect on cognition in old age, which suggests that it may be possible to alter the trajectory of age-related cognitive decline. However, our understanding of which aspects of physical activity that are important for modifying cognition remains incomplete. Adopting an exploratory approach in a sample of 115 healthy older adults (65–75 years), the present cross-sectional study used structural equation modelling to investigate the dissociable associations of physical activity (moderate-to-vigorous activity, derived from 7-day accelerometry) and cardiorespiratory fitness (VO₂ max, derived from maximal treadmill ergometer test) with multiple latent cognitive abilities (working memory, episodic memory, spatial and verbal reasoning). The results showed a significant positive association between fitness and working memory, when physical activity was statistically controlled for, and a positive association of similar point magnitude between physical activity and episodic memory, when fitness was statistically controlled for, although the latter association did not reach statistical significance. The results add to the foundation for a more careful investigation of the dissociable associations of moderate-to-vigorous physical activity and fitness with cognition in old age, and encourages future research to test the hypothesis that cardiorespiratory fitness benefits working memory via general cerebrovascular effects on grey matter volume, whilst moderate-to-vigorous physical activity benefits episodic memory via effects on neuroplastic processes.     

Type of physical exercise and inhibitory function in older adults: An event-related potential study

ObjectivesThe present study was to examine the relationship between exercise type and inhibitory function in older adults using neuroelectric indices.DesignA cross-sectional design was employed in the present study.MethodSixty adults (M = 69.42 years) were categorized into open-skill, closed-skill, and irregular exercise groups according to their history of exercise participation. The participants conducted a flanker task while their behavioral performance and event-related brain potentials were assessed.ResultsThe results indicated that regular exercisers, regardless of exercise type, exhibited a faster reaction time across conditions of the flanker task compared to irregular exercisers. For the P300 amplitude of the open-skill exerciser group, the peak amplitude was larger at the vertex site compared to the frontal site, whereas no site differences were observed in the closed-skill and irregular exerciser groups.ConclusionsThese findings extend current knowledge by suggesting that, for older adults, participation in physical exercise involving increased cognitive demand is associated with better neural efficiency in resource allocation for tasks that require interference control.     

COMT gene polymorphisms,cognitive performance,and physical fitness in older adults

ObjectiveIt is well known that genetic predispositions might influence cognitive performance, particularly in older adults. One gene related to executive functioning is the COMT gene with met/met carriers outperforming val/val carriers in cognitive tasks. Further, it has been shown that fitness is positively related to cognitive functioning in older adults. As both, the COMT genotype and physical exercise have been shown to influence dopamine availability and as changes in dopamine metabolism seem to play a key role in cognitive aging, the aim of this study was to analyze the association of the COMT gene polymorphisms with the relationship between fitness and cognition.DesignWe used a cross-sectional design.MethodSixty-eight healthy older adults between 62 and 79 years of age were analyzed in this study. DNA was extracted from capillary blood samples. Participants performed a modified version of the Flanker Task as an indicator of executive control and a battery of motor and physical tests as indicators of fitness.ResultsHierarchical regression analyses revealed a positive influence of overall fitness and an interactive effect of fitness and COMT polymorphisms on Flanker accuracy performance. Val/val carriers revealed the highest positive correlation between fitness and cognition.ConclusionsOur data suggest that particularly val/val allele carriers benefit from exercise by improved cognitive functioning whereas met/met carriers already perform closer at their optimum level.     

Views on aging and emotional benefits of physical activity: Effects of an exercise intervention in older women

Objectives

This intervention study evaluated the effects of exercise in old age on views on one’s own aging and on direct approach motivation for physical activity. It further examined the mechanism between these variables.

Design

Two hundred forty-seven healthy women aged 70−93 years were randomized to an exercise course (n = 86), an active (n = 85), or a passive control group (n = 76) for a 6-month participation in Berlin, Germany. Activity interventions (3 × 1.5 h/wk) were conducted using standardized manuals.

Method

Group differences in changes of views on aging and direct approach were evaluated by analyses of covariance adjusted for baseline. A mediating effect of direct approach between exercise participation and views on aging was tested with percentile-based bootstrapping.

Results

In contrast to both the active and the passive control groups, higher direct approach, F(2, 226) = 6.97, p = .001, and less aging dissatisfaction, F(2, 225) = 5.39, p = .005, were observed in the exercise group after 6 months. Exercise had an indirect beneficial effect on aging dissatisfaction through direct approach, B = −0.31, 95% CI = −0.68 to −0.05.

Conclusion

In women above 70 years, exercise participation increases direct approach motivation which in turn leads to lower aging dissatisfaction. This shows that exercise holds the potential to overcome subjective ageist bias.     

Benefits of physical exercise on executive functions in older people with Parkinson’s disease

The benefits of physical exercise on cognitive functioning have been reported in the literature, but the potential benefits to slow the eventual decline in executive functioning (EF) caused by neurodegeneration from Parkinson’s Disease (PD) have rarely been studied. Thus the objective of this study was to analyze the effects of a multimodal physical exercise program on EF in older people with Parkinson’s disease. The EF of the older people was evaluated by neuropsychological testing, and for confounding variables such as attention, depressive symptoms and anxiety, before and after intervention. The 20 participants were assigned into Control (CG) and Trained (TG) Groups. The TG participated in generalized physical training for 6 months. The ANOVA showed a significant interaction (p < .05) that indicated a beneficial contribution of training on EF. No significant interactions were found in the results for confounding variables between groups and pre- and post-intervention, which supports the beneficial findings of physical exercise training on EF.     

Beliefs about age-related changes in physical functioning across the adult life span and their relationship with physical activity levels of older adults

Physical activity declines across the adult life span despite the well-established links between physical activity and health-related, psychological, cognitive, and social benefits. We contrasted the beliefs young and older adults hold about how aging affects both physical abilities and physical activity and determined whether older adults’ beliefs about physical aging relate to their engagement in physical activity. Using visual rating scales, 56 young and 49 community-dwelling older adults indicated the extent to which a typical woman or typical man aged 20–90 possesses six different physical abilities and engages in three different types of physical activity. Stereotypes of physical aging were ability- and activity-specific, and older adults endorsed more positive views than their younger peers. Stereotypical beliefs predicted older adults’ engagement in moderate-intensity activity. This study offers intriguing avenues for future research and suggests that better understanding physical aging stereotypes may contribute toward designing interventions that promote lifelong physical activity.     

Habit as mediator of the relationship between prior and later physical activity: A longitudinal study in older adults

ObjectivesHabit has been proposed as an explanation of why prior behavior is a good predictor of later behavior. This study examined whether habit mediates the relationship between prior and later physical activity (PA), within the framework of the attitude-social influences-efficacy (ASE) model and the theory of planned behavior (TPB).DesignA longitudinal design was used.MethodsA total of 1976 older adults completed questionnaires on ASE/TPB constructs and PA at baseline, intention at three months, habit at six months, and PA at twelve months.ResultsPath analyses showed that habit significantly mediates the relationship between prior and later PA, after ASE/TPB variables were taken into account.ConclusionsHabit is a partial solution to the question why prior PA is a good predictor of later PA. It is recommended to incorporate habit into the ASE/TPB model.     

A trial-by-trial analysis reveals more intense physical activity is associated with better cognitive control performance in attention-deficit/hyperactivity disorder

Hyperactivity is a key symptom and the most observable manifestation of attention-deficit/hyperactivity disorder (ADHD). The over-activity associated with ADHD can cause specific challenges in academic settings, extracurricular activities and social relationships. Cognitive control challenges are also well established in ADHD. The current study included 44 children between the ages of 10 and 17 diagnosed with ADHD or who were typically developing (TD), all of whom had no psychiatric co-morbidity or significant learning disorders. Participants wore an actometer on their ankle while performing a flanker paradigm in order to objectively measure their rates of activity in association with cognitive control. Analyses assessed the relationship between frequency and intensity of activity to task accuracy on a trial-by-trial basis. A significant interaction effect between group and performance revealed that more intense movement was associated with better performance in the ADHD group but not in the TD group. The ADHD group demonstrated more intense activity than the TD group during correct (but not error) trials. Within-group, children with ADHD generated higher intensity movements in their correct trials compared to their error trials, whereas the TD group did not demonstrate any within-group differences. These findings suggest that excessive motoric activity associated with clinically significant ADHD symptoms may reflect compensatory efforts to modulate attention and alertness. Future research should systematically explore the relationship between motion in ADHD and how it might be used to improve cognitive performance.     

Effects of behaviour change interventions on physical activity in people with spinal cord injury: A systematic review and meta-analysis

ObjectivesThis review investigated the effectiveness of behaviour-change interventions to improve physical activity (PA) participation in individuals with a spinal cord injury. Additionally, the review sought to analyse the change in PA behaviour that might be expected by utilising behaviour change in PA interventions and what specific intervention characteristics, application of behaviour change theories, and behaviour change techniques are most efficacious.MethodsThe protocol was prospectively registered on PROSPERO: CRD42021252744, and the Preferred Reporting Items for Systematic Reviews and Meta-Analysis guidelines were followed in this review. Eight databases were comprehensively searched using a well-defined strategy developed in collaboration with an academic liaison librarian. Randomised, non-randomised controlled, and non-controlled studies were included in this review; however, controlled and non-controlled studies were analysed separately. Studies were included if participants were older than 16 years and had an SCI of any cause, level or severity, regardless of the time since injury. The behaviour change technique taxonomy version 1 was used to code the intervention characteristics for behaviour modification. The combined effects across studies were pooled in a meta-analysis, and the risk of bias was assessed using the Cochrane Risk of Bias 2 tool.ResultsThe search retrieved 10,155 titles and abstracts. After duplicate removal and screening against the eligibility criteria, 23 studies were included. The overall effect estimate of the change in PA participation in the controlled trials post-intervention was medium (d = 0.50, 95% CI = 0.31–0.70) in favour of behaviour-targeted interventions. The mean difference in PA volume between pre- and post-intervention was an increase of 22 minutes per week (95% CI = 5.96–38.90). Interventions that provided practical support (d = 0.81, 95% CI = 0.46–1.16), which were individualised (d = 0.62, 95% CI = 0.34–0.90) and that utilised monitoring (d = 0.59, 95% CI = 0.34–0.83) had a greater effect on change to PA than those that were group-based and did not utilise those specific techniques.ConclusionsInterventions that target behaviour change to increase PA in people with SCI appear effective. Utilising behaviour change frameworks and specific behaviour change techniques augments PA uptake and levels, and interventions aimed at improving PA in people with SCI should incorporate a behaviour modification component. More research is needed on the isolated effect of intervention structure parameters and specific behaviour change techniques.