发展行为遗传学简介

发展行为遗传学是发展心理学与行为遗传学的交叉学科, 旨在探明遗传与环境对人类心理与行为发展是否存在影响, 如何产生影响, 以及该影响及其作用机制是否随年龄增长而发展变化的问题。该学科与行为遗传学在研究对象、设计和内容等方面存在不同; 开展发展行为遗传学研究需要综合运用心理测量法和行为遗传学研究方法; 未来研究应拓宽和深化候选基因与行为关联性的考察, 并着力探析基因与环境的相互作用机制。     

发展性阅读困难的行为遗传学研究

发展性阅读困难是学龄儿童常见的学习障碍,其病源学问题极其复杂,很多行为遗传学家针对遗传和环境对阅读困难的影响进行了大量的研究。该文对阅读困难的行为遗传学研究进行了回顾,特别是综合介绍了分子遗传学研究所取得的重要成果及不足。最后指出了研究所面临的困难和将来的方向,并对与教育的关系进行了总结与评价。     

人格行为遗传学研究的两类取向

随着行为主义衰落和生物学技术发展,长期遭受“冷遇”的人格行为遗传学研究近些年成为颇受关注的领域,并由数量遗传学取向发展到分子遗传学取向.数量遗传学取向主张运用双生子研究、收养研究等设计来估计群体中遗传因素对人格表现型方差的贡献率,在人格特质、人格障碍、态度与偏好等人格方面做了大量研究.分子遗传学取向主张在DNA水平上用基因测定方法研究特定基因对人格表现型的影响效应,着重从多巴胺、5-羟色胺和去甲肾上腺素三种神经递质路径考察了基因与人格的关系.未来研究要强调在数量遗传设计中加入对特定基因型的直接测量,注重多学科和多范式的有效整合,扩大对健康人群积极人格品质的研究,加强基因对人格的深层作用机制研究和分子医学层面的人格干预研究.     

行为遗传学：从宏观到微观的生命研究

行为遗传学是在多门学科发展的基础上形成的一门交叉学科。从19世纪末期到现在,行为遗传学已跨入第三个世纪。从孟德尔单基因遗传定律到多基因系统与环境交互作用影响复杂的人类行为,从传统的计量遗传学研究到连锁、关联研究再到功能基因组学技术的应用,无论在思想体系还是研究方法上,行为遗传学都取得了突破性进展。尽管行为遗传学在阐明基因究竟怎样影响行为的道路上仍处于起步阶段,但毋庸置疑,这一学科的进步将有助于人类了解自身行为,减轻人类病痛,并最终推动整个社会健康发展。     

多动症的遗传学研究概述

多动症多始于儿童期,并能持续至成年期。传统的家庭、双生子和养子女研究表明,多动症是受遗传影响的。双生子研究现在被用来定义多动症表型,分析性别差异,测试基因对持续性和共病的影响,以及研究遗传与环境的互动。多动症的分子遗传学研究集中在功能候选基因的关联分析上。多动症与DRD4和DRD5的关系比较一致。最新的研究也显示COMT的影响。关联分析（linkage analysis）显示这些单个基因的影响都不大。这个领域还有待于大规模的“全基因关联”分析。至今为止的证据显示,研究基因-表型关联以及基因与环境互动对多动症的影响将日趋重要     

人格研究中的行为遗传学取向的发展

人格的行为遗传学研究,是以研究遗传和环境的差异来解释人格的个体差异的程度为目的,为探讨遗传和环境在个体发展中的作用提供了新的研究途径。该文以天性和教养为突破口,紧紧围绕行为遗传学在人格研究领域的发展脉络:遗传力、环境、特定基因的研究,进一步探讨在个体人格发展过程中遗传和环境的交互作用的关系。     

主动性攻击和反应性攻击的遗传基础研究述评

根据攻击行为的意图可以将攻击分为主动性攻击和反应性攻击。近年来, 研究者对遗传和环境在主动性攻击和反应性攻击发展中的作用进行了探讨, 并获得了两类攻击具有不同遗传和环境基础的重要发现。既有研究主要采用定量行为遗传学研究的范式考察两类攻击的遗传基础, 未来研究应从确定与两类攻击相关的候选基因、遗传基因与环境的交互作用机制、遗传基因作用于两类攻击的神经生物机制等方面展开。     

青少年焦虑、抑郁与偏差行为的行为遗传学研究

焦虑、抑郁和偏差行为等问题的行为遗传学研究有助于了解人类情绪与行为受遗传和环境交互影响的内在机制。近年来,行为遗传学研究方法的迅速发展使科学家们能够更深入地探讨了基因与环境的作用和影响。文章了分析了焦虑、抑郁和偏差行为的行为遗传学研究进展,介绍了国内外双生子研究的发展情况,提出在我国建立双生子数据库,开展有关青少年焦虑、抑郁和偏差行为的行为遗传学研究     

儿童认知发展研究的前沿与动向

近一二十年,得益于认知发展理论的进步和研究方法的新发展,儿童认知发展研究取得了长足的进步。这体现在婴儿研究方兴未艾,一些新课题的出现使一些传统的研究领域重新恢复了活力。同时．发展认知神经科学和认知行为遗传学这两个边沿交叉学科研究蓬勃发展,应用认知发展心理学研究迅速发展,对认知发展心理学研究均产生了巨大的影响。     

儿童虐待与问题行为：基因与环境的作用

当前预防虐待之所以成为儿童保护的重要内容,不仅是法理上的儿童权益保护,也因虐待关联的基因与环境作用对人发展的长期影响。儿童虐待与问题行为关系复杂,已有研究显示,虐待特征、受害者特点是其关联因素,但其内在机制并不清楚。随着分子遗传学的兴起,MAOA、COMT、5-HTT等基因为解释儿童虐待与问题行为的机制提供新视角,重要候选基因可能调节这一关系。未来研究可从动物模型和纵向追踪角度去探究儿童虐待与问题行为关系的易感期、保护因子,完善儿童虐待与个体发展关系的研究图谱。     

人类基因组研究与遗传学的历史教训

第１８届国际遗传学大会达成的八点共识对于人类基因组的研究及其应用具有重要意义,也指明了在遗传学及其应用问题上不同文化之间如何解决它们之间分歧的最佳途径。纳粹德国的优生实践和前苏联李森科学派的兴衰都给我们留下了不可忘记的教训。围绕中国母婴保健法的争论反映了科学、伦理和政策的交叉。我们的基因组研究和遗传服务是为了增进个人的健康和促进家庭的幸福,而不能也不应以减少残疾人口为目标。在基因组研究和遗传服务中     

美国成人学习不良研究及其启示

随着儿童、青少年学习不良研究的逐步深入,近年来,成人学习不良成为美国等西方国家教育心理学研究新的热点。在回顾了成人学习不良概念的提出与确立后,介绍了美国学术界对成人学习不良的筛查和界定标准,并对该领域主要成果从学业发展、阅读困难、元认知和干预研究四个方面进行了概括和分析,指出成人学习不良界定标准的不统一、长期追踪研究的缺乏以及针对成人学习不良心理咨询体系的滞后等已成为当前该领域急待解决的问题。我国应在吸取国外研究成果和经验的基础上,尽快制定出符合自身国情的筛查和诊断标准,掌握学习不良在我国成人群体当中的发生率和分布状况,同时加强相关基础研究和追踪研究,争取在较短时间内建立起我国成人学习不良研究的体系。     

出版视阈中的民国时期中国心理学发展史考察——基于民国时期心理学图书的计量分析

中国科学心理学是在20世纪初复杂的社会背景下通过传入西方心理学而建立和发展起来的.在这一过程中,心理学图书的出版和传播起到了重要作用.文章以《民国时期总书目》中收录的心理学图书为研究对象,通过对心理学图书的年出版量、编著与译著的比较、出版数量的地域差异、分支学科的出版特征等四个方面的出版状况进行计量分析,探讨其形成原因和历史背景,试图从出版视角对民国时期科学心理学在中国的发展做微观的历史考察.     

中国心理学原创性的缺失及应对策略

本文从社会历史、科学、文化、哲学以及研究者和学科层面,分析了我国心理学原创性缺失的原因。提出了面向中国传统文化和哲学,推进本土心理学的研究,强化我国科学技术的创新能力以及用涵化的方式处理引进与发展、创新的关系等策略,以提升我国心理学的原创性。     

Duty of Care,Safety, Normalisation and the Mental Capacity Act: A Discourse Analysis of Staff Arguments about Facilitating Choices for People with Learning Disabilities in UK Services

The benefits of having choice and control for people with learning disabilities 1 are well documented, and front‐line carers often make efforts ensuring that these are facilitated. However, despite this, government policy reports that disempowerment within learning disability services in the UK is a persistent problem. Using critical discursive psychology, 15 interviews with support workers about empowering people with learning disabilities were analysed. Interpretative repertoires about ‘duty of care’, ‘safety’ and ‘normalisation’ and discursive strategies involving ‘comparative evaluations’ were found, which opened speaker positions of granting or withholding choice, assuming responsibility for those in care and constructing service users as lacking capacity. These resources also allowed speakers to regulate the choices of service users and to normalise limited choice in ways that undermined taking up more empowering practices. The findings may explain the persistence of disempowerment within services by indicating how such discourses are deeply entrenched in service talk and are invoked to justify disempowering practices. This is discussed in view of the implications for empowerment and also current legislative frameworks such as the Mental Capacity Act. Copyright © 2014 John Wiley & Sons, Ltd.     

Action-state orientation and the theory of planned behavior: A study of job search in China

Job search is an important element of people’s careers and is especially critical for unemployed individuals. The current study surveyed a sample of 328 unemployed job seekers in China to test hypotheses related to the theory of planned behavior and action-state orientation theory. Results of the three-wave longitudinal study demonstrated that the theory of planned behavior was effective in modeling job-search intention and job-search intensity. Action-state orientation moderated the relationship between attitude and intention, as well as the relationship between intention and intensity. The current study sheds light on the motivational and self-regulatory process of job search and reemployment for Chinese unemployed job seekers.     

Attitudes to Marriage and Sexual Behaviors: A Survey of Gender and Culture Differences in China and United Kingdom

This paper reports a survey carried out among 505 university students in China and 338 students in the United Kingdom. The survey included questions on attitudes toward mate-selection preferences, marriage, and sexual behavior. The findings show that traditional values in mate-selection preferences persist more in China than in the United Kingdom and indicate that, despite a profound social revolution over the last two decades, a relatively conservative sexual culture still exists in China today. Traditional morality and attitudes prevail especially among women. Gender and culture differences are discussed.     

Research priorities in the psychological therapies: View from the British Association for Counselling and Psychotherapy

This paper seeks to summarise recent discussions within the British Association for Counselling and Psychotherapy (BACP) about the strategic direction and priorities for the organisation, the profession as a whole and, ultimately, the service users. The standing research policy commitment to a pluralist approach to research is affirmed and a number of competing approaches are briefly considered. The direction of general policy and specific aims are noted. The paper does not seek to define a BACP position, as such, and is intended to stimulate further debate and discussion which will feed directly into the development of the BACP research policies and activities during this crucial development period.     

The Etiology of Behavior Problems in 7-Year-Old Twins: Substantial Genetic Influence and Negligible Shared Environmental Influence for Parent Ratings and Ratings by Same and Different Teachers

Parent ratings of behavior problems in childhood show substantial genetic influence and modest shared environmental influence. However, few studies have compared these results to teacher ratings and no previous studies have compared same-teacher ratings to different-teacher ratings. 3,714 7-year-old twin pairs in the Twins Early Development Study were rated by parents and teachers on the Strengths and Difficulties Questionnaire. Substantial heritability and negligible shared environmental influence were found for data from all three raters for total behavior problems, hyperactivity, prosocial behavior, peer problems, conduct problems, and emotional symptoms. Sex-limitation models revealed similar results for males and females, although there was some evidence for greater heritability for boys, especially when twins were rated by the same teacher.     

Genetic,Maternal, School,Intelligence, and Media Use Predictors of Adult Criminality: A Longitudinal Test of the Catalyst Model in Adolescence through Early Adulthood

The catalyst model suggests that adult criminality arises from the interaction of genetic and proximal social influences such as family influences, but that distal social influences such as media exposure have only negligible influence. This article uses data from a 13-year longitudinal study of adolescent health to examine the catalyst model. As expected by the catalyst model, adult criminality was best explained by a confluence of genetic and proximal social risk factors. The influence of media exposure on adult criminality was negligible. Implications of these findings for both theory and policy are discussed.