The neural underpinnings of prosody in autism

This study examines the processing of prosodic cues to linguistic structure and to affect, drawing on fMRI and behavioral data from 16 high-functioning adolescents with autism spectrum disorders (ASD) and 11 typically developing controls. Stimuli were carefully matched on pitch, intensity, and duration, while varying systematically in conditions of affective prosody (angry versus neutral speech) and grammatical prosody (questions versus statement). To avoid conscious attention to prosody, which normalizes responses in young people with ASD, the implicit comprehension task directed attention to semantic aspects of the stimuli. Results showed that when perceiving prosodic cues, both affective and grammatical, activation of neural regions was more generalized in ASD than in typical development, and areas recruited reflect heightened reliance on cognitive control, reading of intentions, attentional management, and visualization. This broader recruitment of executive and "mind-reading" brain areas for a relative simple language-processing task may be interpreted to suggest that speakers with high-functioning autism (HFA) have developed less automaticity in language processing and may also suggest that "mind-reading" or theory of mind deficits are intricately bound up in language processing. Data provide support for both a right-lateralized as well as a bilateral model of prosodic processing in typical individuals, depending upon the function of the prosodic information.     

The Comprehension of Syntactic and Affective Prosody by Adults with Autism Spectrum Disorder Without Accompanying Cognitive Deficits

The present study investigates the comprehension of syntactic and affective prosody in adults with autism spectrum disorder without accompanying cognitive deficits (ASD w/o cognitive deficits) as well as age-, education- and gender-matched unimpaired adults, while processing orally presented sentences. Two experiments were conducted: (a) an on-line sentence completion task containing local subject/object ambiguities and (b) an affective prosody task exploring the comprehension of six emotions. The syntactic prosody task revealed that the experimental group performed similar to the control group on the fillers and the object condition. On the other hand, the ASD w/o cognitive deficits group manifested lower accuracy compared to the unimpaired controls in the subject reading condition, as well as slower reaction times in all conditions. In the affective prosody task, the experimental group performed significantly worse than the controls in the recognition of the emotion of surprise, whereas no differences between the experimental and the control group were attested in the recognition of all other emotions. A positive correlation was found between the two tasks in the ASD w/o cognitive deficits group. Thus, individuals with ASD w/o cognitive deficits face slight difficulties with the decoding of prosody, both the syntactic and the affective one. More specifically, these difficulties are attested in the most difficult conditions, i.e. the subject reading and the emotion of surprise.     

The specificity of age-related decline in interpretation of emotion cues from prosody

Older adults are not as good as younger adults at decoding prosodic emotions. We sought to determine the specificity of this finding. Performance of older and younger adults was compared on a prosodic emotion task, a "pure" prosodic emotion task, a linguistic prosody task, and a "pure" linguistic prosody task. Older adults were less accurate at interpreting prosodic emotion cues and nonemotional contours, concurrent semantic processing worsened interpretation, and performance was further degraded when identifying negative emotions and questions. Older adults display a pervasive problem interpreting prosodic cues, but further study is required to clarify the stage at which performance declines.     

Lateralization of visuospatial attention across face regions varies with emotional prosody

It is well-established that linguistic processing is primarily a left-hemisphere activity, while emotional prosody processing is lateralized to the right hemisphere. Does attention, directed at different regions of the talker’s face, reflect this pattern of lateralization? We investigated visuospatial attention across a talker’s face with a dual-task paradigm, using dot detection and language comprehension measures. A static image of a talker was shown while participants listened to speeches spoken in two prosodic formats, emotional or neutral. A single dot was superimposed on the speaker’s face in one of 4 facial regions on half of the trials. Dot detection effects depended on emotion condition—in the neutral condition, discriminability was greater for the right-, than for the left-, side of the face image, and at the mouth, compared to the eye region. The opposite effects occurred in the emotional prosody condition. The results support a model wherein visuospatial attention used during language comprehension is directed by the left hemisphere given neutral emotional prosody, and by the right hemisphere given primarily negative emotional prosodic cues.     

Exogenous and endogenous attention orienting in autism spectrum disorders.

Fifteen children with high-functioning Autism Spectrum Disorder (ASD) and 15 children with typical development completed an attentional cuing task using peripheral cues (exogenous orienting) and central cues (endogenous orienting). Results showed that participants with ASD had impaired exogenous and intact endogenous orienting. The pattern of exogenous orienting was related to motor functioning. Individuals with ASD who had poor motor functioning displayed slowed exogenous orienting. However, individuals with ASD who had relatively good motor functioning showed typical levels of exogenous orienting when given a short time but decreased orienting when given a longer amount of time. These results suggest attention impairments in ASD may not be specific to social orienting and instead may represent a more general orienting impairment.     

口语加工中的词语切分线索

词是语言的基本结构单位, 对词语进行切分是语言加工的重要步骤。口语语流中的切分线索来自于语音、语义和语法三个方面。语音线索包括概率信息、音位配列规则和韵律信息, 韵律信息中还包括词重音、时长和音高等内容, 这些线索的使用在接触语言的早期阶段就逐渐被个体所掌握, 而且在不同的语言背景下有一定的特异性。语法和语义线索属于较高级的线索机制, 主要作用于词语切分过程的后期。后续研究应从语言的毕生发展和语言的特异性两个方面考察口语语言加工中的词语切分线索。     

Low-level visual attention and its relation to joint attention in autism spectrum disorder

Visual attention is integral to social interaction and is a critical building block for development in other domains (e.g., language). Furthermore, atypical attention (especially joint attention) is one of the earliest markers of autism spectrum disorder (ASD). The current study assesses low-level visual attention and its relation to social attentional processing in youth with ASD and typically developing (TD) youth, aged 7 to 18 years. The findings indicate difficulty overriding incorrect attentional cues in ASD, particularly with non-social (arrow) cues relative to social (face) cues. The findings also show reduced competition in ASD from cues that remain on-screen. Furthermore, social attention, autism severity, and age were all predictors of competing cue processing. The results suggest that individuals with ASD may be biased towards speeded rather than accurate responding, and further, that reduced engagement with visual information may impede responses to visual attentional cues. Once attention is engaged, individuals with ASD appear to interpret directional cues as meaningful. These findings from a controlled, experimental paradigm were mirrored in results from an ecologically valid measure of social attention. Attentional difficulties may be exacerbated during the complex and dynamic experience of actual social interaction. Implications for intervention are discussed.     

Behind the wheels with autism and ADHD: Brain networks involved in driving hazard detection

Driving is a cognitively challenging task, and many individuals with autism spectrum disorder (ASD) or with attention-deficit/hyperactivity disorder (ADHD) struggle to drive safely and effectively. Previous evidence suggests that core neuropsychological deficits in executive functioning (EF) and theory of mind (ToM) may impact driving in ASD and ADHD. This functional magnetic resonance imaging (fMRI) study compares the brain mechanisms underlying ToM and EF during a hazard perception driving task. Forty-six licensed drivers (14 ASD, 17 ADHD, 15 typically developing (TD)), ages 16–27 years, viewed a driving scenario in the MRI scanner and were instructed to respond to driving hazards that were either “social” (contained a human component such as a pedestrian) or “nonsocial” (physical objects such as a barrel). All groups of participants recruited regions part of the “social brain” (anterior insula, angular gyrus, right middle occipital gyrus, right cuneus/precuneus, and right inferior frontal gyrus) when processing social hazards, and regions associated with motor planning and object recognition (postcentral gyrus, precentral gyrus, and supplementary motor area) when processing nonsocial hazards. While there were no group differences in brain activation during the driving task, years licensed was predictive of greater prefrontal and temporal activation to social hazards in all participants. Findings of the current study suggest that high-functioning ASD and ADHD licensed drivers may be utilizing similar cognitive resources as TD controls for decisions related to driving-related hazard detection.     

情绪韵律调节情绪词识别的ERP研究

采用韵律/词汇干扰范式和延迟匹配任务, 通过两个ERP实验, 考察了汉语口语中情绪韵律能否、以及如何调节情绪词的识别。实验一中, 不同类型的情绪韵律分组呈现, ERP结果显示, 同与情绪韵律效价一致的情绪词相比, 与情绪韵律效价不一致的情绪词诱发了走向更负的P200、N300和N400成分; 实验二中, 不同类型的情绪韵律随机呈现, 上述效价一致性效应依然存在。实验结果表明, 情绪韵律能够调节情绪词识别, 主要表现在对情绪词的音韵编码和语义加工的双重易化上。     

韵律特征研究

介绍从知觉、认知和语料库分析角度对汉语韵律特征进行的一系列研究。（1）韵律特征知觉：用实验心理学和知觉标注的语料库分析方法,研究汉语语调和音高下倾与降阶问题,语句和语篇中知觉可以区分的韵律层级及相关的声学线索。研究结果支持汉语语调的双线模型理论和语句音高下倾的存在;证明语篇中知觉可以区分的韵律边界是小句、句子和段落,及其知觉相关的声学线索。（2）韵律特征与其他语言学结构的关系：在标注的语料库的基础上,用常规统计方法研究语句常规重音分布规律、语篇信息结构与重音的关系、并用决策树方法研究根据文本信息确定韵律短语边界和焦点的规则。（3）韵律特征在语篇理解中的作用：用实验心理学方法和脑电指标研究韵律对语篇信息整合和指代理解的影响,揭示其作用的认知和神经机制。讨论了这些研究结果对语音工程、语音学理论和心理语言学研究的实践和理论意义     

Systems Factorial Technology provides new insights on global-local information processing in autism spectrum disorders

Previous studies of global-local processing in autism spectrum disorders (ASDs) have indicated mixed findings, with some evidence of a local processing bias, or preference for detail-level information, and other results suggesting typical global advantage, or preference for the whole or gestalt. Findings resulting from this paradigm have been used to argue for or against a detail focused processing bias in ASDs, and thus have important theoretical implications. We applied Systems Factorial Technology, and the associated Double Factorial Paradigm (both defined in the text), to examine information processing characteristics during a divided attention global-local task in high-functioning individuals with an ASD and typically developing controls. Group data revealed global advantage for both groups, contrary to some current theories of ASDs. Information processing models applied to each participant revealed that task performance, although showing no differences at the group level, was supported by different cognitive mechanisms in ASD participants compared to controls. All control participants demonstrated inhibitory parallel processing and the majority demonstrated a minimum-time stopping rule. In contrast, ASD participants showed exhaustive parallel processing with mild facilitatory interactions between global and local information. Thus our results indicate fundamental differences in the stopping rules and channel dependencies in individuals with an ASD.     

“Hunting with a knife and … fork”: Examining central coherence in autism,attention deficit/hyperactivity disorder,and typical development with a linguistic task

A local processing bias, referred to as “weak central coherence,” has been postulated to underlie key aspects of autism spectrum disorder (ASD). Little research has examined whether individual differences in this cognitive style can be found in typical development, independent of intelligence, and how local processing relates to executive control. We present a brief and easy-to-administer test of coherence requiring global sentence completions. We report results from three studies assessing (a) 176 typically developing (TD) 8- to 25-year-olds, (b) individuals with ASD and matched controls, and (c) matched groups with ASD or attention deficit/hyperactivity disorder (ADHD). The results suggest that the Sentence Completion Task can reveal individual differences in cognitive style unrelated to IQ in typical development, that most (but not all) people with ASD show weak coherence on this task, and that performance is not related to inhibitory control. The Sentence Completion Task was found to be a useful test instrument, capable of tapping local processing bias in a range of populations.     

Resolving ambiguity: a psycholinguistic approach to understanding prosody processing in high-functioning autism

Individuals with autism exhibit significant impairments in prosody production, yet there is a paucity of research on prosody comprehension in this population. The current study adapted a psycholinguistic paradigm to examine whether individuals with autism are able to use prosody to resolve syntactically ambiguous sentences. Participants were 21 adolescents with high-functioning autism (HFA), and 22 typically developing controls matched on age, IQ, receptive language, and gender. The HFA group was significantly less likely to use prosody to disambiguate syntax, but scored comparably to controls when syntax alone or both prosody and syntax indicated the correct response. These findings indicate that adolescents with HFA have difficulty using prosody to disambiguate syntax in comparison to typically developing controls, even when matched on chronological age, IQ, and receptive language. The implications of these findings for how individuals with autism process language are discussed.     

Sensitivity to probabilistic orthographic cues to lexical stress in adolescent speakers with autism spectrum disorder and typical peers

Lexical stress refers to the opposition of strong and weak syllables within polysyllabic words and is a core feature of the English prosodic system. There are probabilistic cues to lexical stress present in English orthography. For example, most disyllabic English words ending with the letters "-ure" have first-syllable stress (e.g., "pasture", but note words such as "endure"), whereas most ending with "-ose" have second-syllable stress (e.g., "propose", but note examples such as "glucose"). Adult native speakers of English are sensitive to these probabilities during silent reading. During testing, they tend to assign first-syllable stress when reading a nonword such as "lenture" but second-syllable stress when reading "fostpose" (Arciuli & Cupples, 2006 ). Difficulties with prosody, including problems processing lexical stress, are a notable feature of autism spectrum disorder (ASD). The current study investigated the ability of adolescents with ASD (13-17 years of age) to show this sensitivity compared with a group of typically developing peers. Results indicated reduced sensitivity to probabilistic cues to lexical stress in the group with ASD. The implications of these findings are discussed.     

老年人群的韵律感知

老龄化导致听觉系统、认知功能有所衰退。老年人群的言语理解能力减弱, 韵律信息解析存在困难。老年人对重音、语调、语速等语言韵律感知能力退化, 对情感韵律的加工也出现问题, 特别是消极情绪韵律加工减退较快。老年疾病进一步加深韵律加工难度, 韵律感知呈现出与特定疾病的相关性。未来研究需考察不同语言背景老年人群的韵律感知表现与机制、复杂交流环境的影响、韵律感知障碍对老年疾病的预测、韵律感知的早期干预与复健等问题。     

Contextual influences of emotional speech prosody on face processing: How much is enough?

The influence of emotional prosody on the evaluation of emotional facial expressions was investigated in an event-related brain potential (ERP) study using a priming paradigm, the facial affective decision task. Emotional prosodic fragments of short (200-msec) and medium (400-msec) duration were presented as primes, followed by an emotionally related or unrelated facial expression (or facial grimace, which does not resemble an emotion). Participants judged whether or not the facial expression represented an emotion. ERP results revealed an N400-like differentiation for emotionally related prime-target pairs when compared with unrelated prime-target pairs. Faces preceded by prosodic primes of medium length led to a normal priming effect (larger negativity for unrelated than for related prime-target pairs), but the reverse ERP pattern (larger negativity for related than for unrelated prime-target pairs) was observed for faces preceded by short prosodic primes. These results demonstrate that brief exposure to prosodic cues can establish a meaningful emotional context that influences related facial processing; however, this context does not always lead to a processing advantage when prosodic information is very short in duration.     

Self-referential memory in autism spectrum disorder and typical development: Exploring the ownership effect

Owned objects occupy a privileged cognitive processing status and are viewed almost as extensions of the self. It has been demonstrated that items over which a sense of ownership is felt will be better remembered than other items (an example of the “self-reference effect”). As autism spectrum disorder (ASD) is characterised by an a typical self-concept, people with ASD may not demonstrate this “ownership effect”. Two experiments were conducted which replicate and extend Cunningham, Turk, MacDonald, and Macrae (2008). In Experiment 1, neurotypical adults completed a card sorting task and cards belonging to the ‘self’ were better remembered than cards belonging to another person. In Experiment 2, adults with ASD recalled self- and other owned items equally well. These results shed light both on the relation between sense of self and the ownership effect, and the nature of the self-concept in ASD.     

Converging evidence of configural processing of faces in high-functioning adults with autism spectrum disorders

There is conflicting evidence about whether individuals with autism spectrum disorder (ASD) demonstrate configural processing of faces. We examined two types of configural processing of unfamiliar faces in high-functioning adults with ASD: Holistic processing (processing a face as a gestalt percept) and processing of second-order relations (the spatial relations among facial features, e.g., distance between two eyes). Compared to age- and IQ-matched typical adults, 17 adults with ASD demonstrated normal holistic processing (as demonstrated by the composite face effect), normal sensitivity to second-order relations in upright faces, and the expected disruption of sensitivity to second-order relations in inverted faces. They were also normal in using the internal features and shape of the external contour to make same/different judgements about facial identity. The results provide converging evidence of configural processing of unfamiliar faces in high-functioning adults with ASD, and bring into question the generalizability of previous reports of abnormal face processing in individuals with ASD.