躯体疾病和抑郁障碍共病的诊断、评估及治疗原则

躯体疾病和抑郁障碍共病已经成为一个越来越严重的临床和全球公共健康问题.共病的躯体疾病与抑郁障碍之间存在着双向的联系,即一种疾病对另一种疾病的发生、发展、预后以及治疗有消极的作用.本文就躯体疾病和抑郁障碍共病的流行病学、临床评估、诊断及治疗原则作一综述.     

抑郁焦虑共病研究及其辩证思维

抑郁、焦虑障碍是临床上很常见的两种疾病,两者之间的症状具有重叠性,共病率很高;目前由于两者的病因和发病机制不太明了,很难做出全面系统的判断.对抑郁、焦虑共病现象采取辩证的思维方法、科学的研究方法,以期探讨共病现象的本质及其规律,为临床诊断、治疗、预防提供更全面、更有效的措施与方案.     

当代精神病学的现状与思考

1 当代精神病学的标志性成果 1.1临床精神病学方面 1.1.1诊断标准[1] 很长一段时期,精神疾病的诊断没有一个公认的标准.诊断主要是根据患者的临床表象和医生自身的临床经验而作出的,可变性和随意性都很大,因而诊断的不一致性在精神科医生之间是一个司空见惯的现象.美国华盛顿大学的精神科医师Feighner制定了第一个操作性较强的精神分裂症的诊断标准,此后美国的DSM、WHO的ICD和我国的CCMD系统均制定了较全面的精神疾病的诊断标准.尽管它们的分类理论和制定诊断标准的规则不尽相同,也尽管每个系统的诊断标准都还很有必要进行不断的完善和修订,但是,诊断标准为消除医生之间、学派之间的诊断分歧功莫大焉,无论对精神病学的临床和研究工作,都是一个划时代的进步.     

抑郁焦虑共病研究及其辩证思维

抑郁、焦虑障碍是临床上很常见的两种疾病,两者之间的症状具有重叠性,共病率很高;目前由于两者的病因和发病机制不太明了,很难做出全面系统的判断。对抑郁、焦虑共病现象采取辩证的思维方法、科学的研究方法,以期探讨共病现象的本质及其规律,为临床诊断、治疗、预防提供更全面、更有效的措施与方案。     

躯体形式障碍的优化诊治

躯体形式障碍是精神科常见的一种神经症,该病具有较高的发病率,占用了大量的医疗资源,但临床识别率和有效治疗率却相当低.围绕躯体形式障碍的特点及其优化诊治作一些探讨,利于提高社会和非精神科医生对该病的认识,减少医疗资源的过度消耗,使疾病得到早期有效治疗.     

当代精神病学的现状与思考

1当代精神病学的标志性成果1.1临床精神病学方面1.1.1诊断标准[1]很长一段时期,精神疾病的诊断没有一个公认的标准。诊断主要是根据患者的临床表象和医生自身的临床经验而作出的,可变性和随意性都很大,因而诊断的不一致性在精神科医生之间是一个司空见惯的现象。美国华盛顿大学     

由网络成瘾列为精神疾病反思医学化倾向

由于精神疾病的诊断特点,精神科中的医学化现象尤为突出.但精神科的这种现象会产生不当的行为控制、个体与社会的隔阂等弊端.一些网络成瘾的矫治措施限制或剥夺被矫治青少年的人身自由,有的已经带有对精神病性障碍患者进行强制性医疗的色彩.网络成瘾目前归为精神疾病的科学依据不足、容易引起误解和误导,是医学化在精神科中的又一表现.     

美国人格障碍共病问题研究介评

在美国,自从DSM体系建立起来,人格障碍就一直受到研究者及临床人员的关注。随着DSM-III将人格障碍归于独立的一轴,发展起全新的诊断思路,人格障碍的共病问题就尤其受到了重视。该文首先介绍了共病问题的状况及主要的几种解释模型,然后就该领域出现的应对方式及研究方案作了系统总结,最后还就如何认识共病问题等提出了思考     

用生物心理社会医学模式指导疾病的诊治

惊恐障碍作为一种精神科疾病,由于伴有明显的躯体化症状,使大多患者首诊于综合医院非精神科,极易引起该病的误诊误治,同时也浪费了大量的卫生资源.针对这一情况,本期"临床决策研究"栏目中熊新英撰写的"从惊恐障碍看生物心理社会医学模式的必要性和紧迫性",对于惊恐障碍就诊于综合医院误诊率高的原因及高误诊率导致的后果进行了分析,并提出了相应的对策.     

有关精神疾病共病研究的几点思考

在过去的 2 0年中 ,许多研究已证实 ,精神障碍中存在大量共病[1] ,并且共病研究具有重要的临床意义[2 ] 。但由于种种原因 ,很难找到可比较的有关共病研究的资料。本文就影响共病研究的几个问题作一阐述。1　样本问题1 1　患病率具有很高患病率的两种障碍 ,许多人只是偶然地患上了两种障碍。这种偶然共患的障碍可能影响人群中这些障碍共病的基础发生率。1 2　样本临床样本的共病率很可能比普通人群高。因为患多个障碍的患者比患单个障碍的患者具有较高的寻求治疗的可能性 ,并且一个人由于一种特定的障碍寻求治疗的概率可能会因一种继发的共…     

Systematic approach to the diagnosis of lysosomal storage disorders

Disorders that arise as a result of lysosomal dysfunction represent some of the most challenging diagnostic problems in medicine. Not only are these disorders infrequently seen, but they may also present with signs and symptoms that mimic perinatal injury, food intolerance, or the sequellae of neonatal infection. Misidentification can lead to significant delay in diagnosis. Ironically, as the prevailing economic climate places increasing time constraints on practicing physicians, medical research is providing treatment strategies and management techniques that are most effective if applied early in the course of the disease. Most lysosomal storage disorders can now be definitively diagnosed once the signs are recognized. In many cases the benefits of early diagnosis, enlightened management, and appropriate referral are considerable. The aim of this paper is to demystify this elusive class of diseases, to promote clinical vigilance in their detection, and to provide a systematic approach to diagnosis when clinical suspicion is aroused.     

Differentiating Sexual Thoughts in Obsessive-Compulsive Disorder From Paraphilias and Nonparaphilic Sexual Disorders

Recurrent sexual thoughts characterize several different psychological disorders, most notably obsessive-compulsive disorder (OCD), paraphilias, and nonparaphilic sexual disorders (NPSDs). Many clinicians are aware of the rule of thumb that sexual thoughts in OCD are personally distressing, whereas sexual thoughts in paraphilias and NPSDs are not distressing to the individual experiencing these thoughts, and they rely on this heuristic to inform diagnosis. This is problematic because distress alone is not a reliable diagnostic differentiator; as a result, misdiagnosis is common. Given the negative consequences of misdiagnosis, including worsening of symptoms, treatment dropout, and potential harm to individuals experiencing these thoughts or those who are targets of these thoughts, the purpose of this paper is to help clinicians identify and differentiate repetitive sexual obsessions in OCD from repetitive sexual thoughts in paraphilias and NPSDs. A clinical case example is provided along with pivotal areas of questioning to aid in differential diagnosis.     

Eine Schlafstörung kommt selten allein

In the clinical routine insomnia disorders are often merely seen as symptoms of the underlying disease and are therefore not considered relevant enough for diagnostic clarification and initiation of specific treatment. The following article intends to give an overview of the differential diagnosis of nonorganic insomnia and underlines the importance of cognitive behavioral therapy in this context, which is substantiated by two case studies.     

儿童支气管哮喘诊断的几点思考

支气管哮喘（以下简称哮喘）是小儿常见的慢性气道疾病。5岁及以下儿童哮喘的诊断极为困难,是富有挑战性的;因为诊断只能依靠临床判断、症状评价和体征分析。病毒感染所至的喘息在婴幼儿期很常见,与哮喘鉴别较困难。目前还没有诊断婴幼儿期哮喘的特异检测手段和方法,因此诊断需要综合考虑,包括反复喘息的类型、特异体质病史、哮喘危险因素、长期随访、广泛鉴别诊断和观察对支气管舒张剂及抗炎治疗的反应。     

Therapieresistente Depression – eine differenzialdiagnostische Herausforderung

Background

Diagnosis and treatment of major depression is part of daily routine in psychiatric practice. We therefore rely on the latest ICD-10 and the described symptoms. However, is this decision always obvious, and which differential diagnostic considerations should be made, especially for patients with treatment-resistant depression or in elderly patients?

Method

A clinical case report is described, taking into consideration the results of a literature search and national and international guidelines.

Results

Major depression is usually part of daily routine in the psychiatric hospital. It is one of the most common diagnoses; the estimated lifetime prevalence of unipolar major depression is 12?% and continues to increase. But what should be done, if symptoms continue to deteriorate, despite guideline-based treatment? The following case report shows that in this situation further diagnostic procedures are needed and necessary. An 80-year-old man is transferred to a psychiatric ward because of depressive symptoms. Despite adequate treatment, the psychiatric state deteriorates. Finally, the diagnosis of normal pressure hydrocephalus (NPH) is made with the direct consequence of further treatment options. Especially the possible overlap of symptoms for depression, dementia, and NPH are shown, thus, making the differential diagnosis challenging.

Conclusion

In 80?% of cases, NPH remains unrecognized and untreated. Similarities in the symptoms lead to the difficulty of distinguishing NPH from other neurodegenerative disorders and, as in this case report, also from major depression. In case of NPH, early diagnosis and treatment are important because if the disease is too advanced, clinical improvement is unlikely. Therefore, in cases of treatment-resistant major depression it is advisable to perform additional diagnostic tests and to consult with interdisciplinary neurology and neuroradiology teams.     

Somatic complaints in anxious children

Although stomachaches and headaches are considered characteristic of children with anxiety disorders, there is converging evidence that a broader range of somatic symptoms may be associated with children's expressions of anxiety. The purpose of this study was to determine the prevalence of somatic complaints in anxious children. The results indicated that children with anxiety disorders endorsed the presence of many different somatic complaints, and that contrary to clinical intuition, stomaches and headaches were not among the most commonly reported symptoms. In addition, the anxious children endorsed significantly more somatic complaints when compared to normal controls. Furthermore, the symptom pattern reported by anxious children indicated the presence of both the somatic and cognitive components usually associated with panic attacks, although none of the children met diagnostic criteria for panic disorder. The results are discussed in terms of the contribution of somatic symptoms to the understanding of anxiety disorders in children.     

Differential diagnosis of malingering and factitious disorder with physical symptoms

The present article attempts to clarify the difficult diagnostic discrimination between malingering and factitious disorder with physical symptoms. It is proposed that diagnostic evaluations focusing on the patient's observed symptomatology will be limited in their accuracy and utility. Instead, a longitudinal approach is needed to include the course of the disorder over time, its response to treatment, and the proposed etiology of the disorder. It is hoped that with a better understanding of these two disorders, prompt and accurate diagnosis can lay the foundation for effective management of both malingering and factitious disorders.     

Begutachtung von somatoformen Störungen

As a result of their prevalence somatoform disorders represent a substantial burden not only for health care systems but also for social security and pension programs around the world. In fact, in recent years there has been a steady increase in the number of applicants filing for disability pensions due to such disorders. Recent studies focus on the relationship between biological, psychological and social factors and the subjective experience of somatoform symptoms and their concomitant impairments. Despite this progress, diagnostic work in general remains a challenge. The purpose of this paper is first to discuss a dimensional diagnostic system for somatoform disorders. Secondly based on the dimensions of this diagnostic system, considerations regarding the differentiation of the diagnosis “pain disorder” will be made. Furthermore, considerations concerning the severity and prognosis of somatoform disorders are presented. These considerations should help to assess vocational disability.     

Die Abschaffung der somatoformen Störungen durch DSM-5 – ein akademischer Schildbürgerstreich?

The new fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) has introduced “somatic symptom disorder” as a diagnosis which is no longer differentiated into medically unexplained and explained physical symptoms. As a consequence, the status of somatoform disorders as an independent clinical group is called into question. Against all original intentions, the semantic, conceptual and practical problems of the previous classification have not been solved. The validity of the new diagnosis is doubtful because of its over-inclusive character. Further points of criticism are the less than optimal selection of psychological features, the abandonment of hypochondriasis as a homogeneous concept and imprecise workmanship of the diagnostic criteria where exclusion criteria needed for differential diagnosis are missing.